Converting structural information into an allosteric-energy-based picture for elongation factor Tu activation by the ribosome

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 24, 2011, Pages 9827-9832

  Adamczyk, Andrew J ^a   Warshel, Arieh ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Allostery; Enzymatic catalysis; Preorganization

Indexed keywords

AMINOACYL TRANSFER RNA; ELONGATION FACTOR TU; GUANOSINE TRIPHOSPHATASE;

ALLOSTERISM; ARTICLE; ENERGY TRANSFER; ENZYME ACTIVATION; MOLECULAR STABILITY; MUTANT; PRIORITY JOURNAL; PROTEIN STRUCTURE; QUANTITATIVE ANALYSIS; RIBOSOME; SIGNAL TRANSDUCTION; SIMULATION;

ALLOSTERIC REGULATION; BINDING SITES; CATALYTIC DOMAIN; ENZYME ACTIVATION; GTP PHOSPHOHYDROLASES; GUANOSINE TRIPHOSPHATE; HYDROLYSIS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUTATION; PEPTIDE ELONGATION FACTOR TU; PROTEIN STRUCTURE, TERTIARY; RIBOSOMES; STATIC ELECTRICITY; THERMODYNAMICS;

EID: 79959935915     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1105714108     Document Type: Article

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