Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 4, 2009, Pages 1063-1068

  Villa, Elizabeth ^a   Sengupta, Jayati ^b,g   Trabuco, Leonardo G ^a   LeBarron, Jamie ^b   Baxter, William T ^b   Shaikh, Tanvir R ^b   Grassucci, Robert A ^c   Nissen, Poul ^d   Ehrenberg, Måns ^e   Schulten, Klaus ^a,f   Frank, Joachim ^c  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b WADSWORTH CENTER   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d AARHUS UNIVERSITY   (Denmark)

^e UPPSALA UNIVERSITY   (Sweden)

^f University of Illinois at Urbana Champaign   (United States)

^g INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

cryo EM; Decoding; Flexible fitting; GTPase; Ternary complex

Indexed keywords

AMINOACYL TRANSFER RNA; ELONGATION FACTOR TU; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATE; MOCIMYCIN; RIBOSOME PROTEIN; RIBOSOME PROTEIN L12; RICIN; RNA 16S; TRANSFER RNA; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVATION; ESCHERICHIA COLI; HYDROPHOBICITY; MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN HYDROLYSIS; PROTEIN STRUCTURE; RIBOSOME; SARCINA; SIGNAL TRANSDUCTION;

CRYOELECTRON MICROSCOPY; ENZYME ACTIVATION; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GUANOSINE TRIPHOSPHATE; HISTIDINE; HYDROLYSIS; HYDROPHOBICITY; MODELS, MOLECULAR; PEPTIDE ELONGATION FACTOR TU; PROTEIN STRUCTURE, SECONDARY; RIBOSOMAL PROTEINS; RIBOSOMES; RNA, TRANSFER; SIGNAL TRANSDUCTION;

ESCHERICHIA COLI;

EID: 59049096394     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0811370106     Document Type: Article

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