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Volumn 26, Issue 37, 2006, Pages 9462-9470

Activated c-Jun N-terminal kinase is required for axon formation

Author keywords

ATF 2; Axon; Axon formation; Axonogenesis; c Jun N terminal kinase; JIP 1; JNK; SP600125

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BIOLOGICAL MARKER; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR 2; UNCLASSIFIED DRUG;

EID: 33748689930     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2625-06.2006     Document Type: Article
Times cited : (139)

References (60)
  • 1
    • 0033950501 scopus 로고    scopus 로고
    • Axon formation: A molecular model for the generation of neuronal polarity
    • Andersen SS, Bi GQ (2000) Axon formation: a molecular model for the generation of neuronal polarity. BioEssays 22:172-179.
    • (2000) BioEssays , vol.22 , pp. 172-179
    • Andersen, S.S.1    Bi, G.Q.2
  • 2
    • 29144502438 scopus 로고    scopus 로고
    • Key regulators in neuronal polarity
    • Arimura N, Kaibuchi K (2005) Key regulators in neuronal polarity. Neuron 48:881-884.
    • (2005) Neuron , vol.48 , pp. 881-884
    • Arimura, N.1    Kaibuchi, K.2
  • 4
    • 0035822634 scopus 로고    scopus 로고
    • Bistability in the JNK cascade
    • Bagowski CP, Ferrell Jr JE (2001) Bistability in the JNK cascade. Curr Biol 11:1176-1182.
    • (2001) Curr Biol , vol.11 , pp. 1176-1182
    • Bagowski, C.P.1    Ferrell Jr., J.E.2
  • 7
    • 21844475890 scopus 로고    scopus 로고
    • Constitutively active cytoplasmic c-Jun N-terminal kinase 1 is a dominant regulator of dendritic architecture: Role of microtubule-associated protein 2 as an effector
    • Björkblom B, Östman N, Hongisto V, Komarovski V, Filen JJ, Nyman TA, Kallunki T, Courtney MJ, Coffey ET (2005) Constitutively active cytoplasmic c-Jun N-terminal kinase 1 is a dominant regulator of dendritic architecture: role of microtubule-associated protein 2 as an effector. J Neurosci 25:6350-6361.
    • (2005) J Neurosci , vol.25 , pp. 6350-6361
    • Björkblom, B.1    Östman, N.2    Hongisto, V.3    Komarovski, V.4    Filen, J.J.5    Nyman, T.A.6    Kallunki, T.7    Courtney, M.J.8    Coffey, E.T.9
  • 8
    • 0346037264 scopus 로고    scopus 로고
    • JNK1 is required for maintenance of neuronal microtubules and controls phosphorylation of microtubule-associated proteins
    • Chang L, Jones Y, Ellisman MH, Goldstein LS, Karin M (2003) JNK1 is required for maintenance of neuronal microtubules and controls phosphorylation of microtubule-associated proteins. Dev Cell 4:521-533.
    • (2003) Dev Cell , vol.4 , pp. 521-533
    • Chang, L.1    Jones, Y.2    Ellisman, M.H.3    Goldstein, L.S.4    Karin, M.5
  • 9
    • 0034667705 scopus 로고    scopus 로고
    • Dual roles for c-Jun N-terminal kinase in developmental and stress responses in cerebellar granule neurons
    • Coffey ET, Hongisto V, Dickens M, Davis RJ, Courtney MJ (2000) Dual roles for c-Jun N-terminal kinase in developmental and stress responses in cerebellar granule neurons. J Neurosci 20:7602-7613.
    • (2000) J Neurosci , vol.20 , pp. 7602-7613
    • Coffey, E.T.1    Hongisto, V.2    Dickens, M.3    Davis, R.J.4    Courtney, M.J.5
  • 10
    • 0029055812 scopus 로고
    • The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
    • Coso OA, Chiariello M, Yu JC, Teramoto H, Crespo P, Xu N, Miki T, Gutkind JS (1995) The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell 81:1137-1146.
    • (1995) Cell , vol.81 , pp. 1137-1146
    • Coso, O.A.1    Chiariello, M.2    Yu, J.C.3    Teramoto, H.4    Crespo, P.5    Xu, N.6    Miki, T.7    Gutkind, J.S.8
  • 12
    • 0034644522 scopus 로고    scopus 로고
    • Signal transduction by the JNK group of MAP kinases
    • Davis RJ (2000) Signal transduction by the JNK group of MAP kinases. Cell 103:239-252.
    • (2000) Cell , vol.103 , pp. 239-252
    • Davis, R.J.1
  • 14
    • 0023492528 scopus 로고
    • Experimentally induced alteration in the polarity of developing neurons
    • Dotti CG, Banker GA (1987) Experimentally induced alteration in the polarity of developing neurons. Nature 330:254-256.
    • (1987) Nature , vol.330 , pp. 254-256
    • Dotti, C.G.1    Banker, G.A.2
  • 15
    • 0023905661 scopus 로고
    • The establishment of polarity by hippocampal neurons in culture
    • Dotti CG, Sullivan CA, Banker GA (1988) The establishment of polarity by hippocampal neurons in culture. J Neurosci 8:1454-1468.
    • (1988) J Neurosci , vol.8 , pp. 1454-1468
    • Dotti, C.G.1    Sullivan, C.A.2    Banker, G.A.3
  • 16
    • 0033179590 scopus 로고    scopus 로고
    • Local presentation of substrate molecules directs axon specification by cultured hippocampal neurons
    • Esch T, Lemmon V, Banker G (1999) Local presentation of substrate molecules directs axon specification by cultured hippocampal neurons. J Neurosci 19:6417-6426.
    • (1999) J Neurosci , vol.19 , pp. 6417-6426
    • Esch, T.1    Lemmon, V.2    Banker, G.3
  • 17
    • 0036532226 scopus 로고    scopus 로고
    • Self-perpetuating states in signal transduction: Positive feedback, double-negative feedback and bistability
    • Ferrell Jr JE (2002) Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability. Curr Opin Cell Biol 14:140-148.
    • (2002) Curr Opin Cell Biol , vol.14 , pp. 140-148
    • Ferrell Jr., J.E.1
  • 19
    • 0024551137 scopus 로고
    • Experimental observations on the development of polarity by hippocampal neurons in culture
    • Goslin K, Banker G (1989) Experimental observations on the development of polarity by hippocampal neurons in culture. J Cell Biol 108:1507-1516.
    • (1989) J Cell Biol , vol.108 , pp. 1507-1516
    • Goslin, K.1    Banker, G.2
  • 20
    • 0028905076 scopus 로고
    • Transcription factor ATF2 regulation by the JNK signal transduction pathway
    • Gupta S, Campbell D, Derijard B, Davis RJ (1995) Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science 267:389-393.
    • (1995) Science , vol.267 , pp. 389-393
    • Gupta, S.1    Campbell, D.2    Derijard, B.3    Davis, R.J.4
  • 22
    • 0034931503 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis
    • Han Z, Boyle DL, Chang L, Bennett B, Karin M, Yang L, Manning AM, Firestein GS (2001) c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis. J Clin Invest 108:73-81.
    • (2001) J Clin Invest , vol.108 , pp. 73-81
    • Han, Z.1    Boyle, D.L.2    Chang, L.3    Bennett, B.4    Karin, M.5    Yang, L.6    Manning, A.M.7    Firestein, G.S.8
  • 23
    • 0035033952 scopus 로고    scopus 로고
    • Signalling for survival and death in neurones: The role of stress-activated kinases, JNK and p38
    • Harper SJ, LoGrasso P (2001) Signalling for survival and death in neurones: the role of stress-activated kinases, JNK and p38. Cell Signal 13:299-310.
    • (2001) Cell Signal , vol.13 , pp. 299-310
    • Harper, S.J.1    LoGrasso, P.2
  • 24
    • 0032444348 scopus 로고    scopus 로고
    • Inducible and constitutive transcription factors in the mammalian nervous system: Control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins
    • Herdegen T, Leah JD (1998) Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins. Brain Res Brain Res Rev 28:370-490.
    • (1998) Brain Res Brain Res Rev , vol.28 , pp. 370-490
    • Herdegen, T.1    Leah, J.D.2
  • 26
    • 33644870579 scopus 로고    scopus 로고
    • A change in the selective translocation of the kinesin-1 motor domain marks the initial specification of the axon
    • Jacobson C, Schnapp B, Banker G (2006) A change in the selective translocation of the kinesin-1 motor domain marks the initial specification of the axon. Neuron 49:797-804.
    • (2006) Neuron , vol.49 , pp. 797-804
    • Jacobson, C.1    Schnapp, B.2    Banker, G.3
  • 27
    • 0030690116 scopus 로고    scopus 로고
    • Inhibition of axonal growth by brefeldin A in hippocampal neurons in culture
    • Jareb M, Banker G (1997) Inhibition of axonal growth by brefeldin A in hippocampal neurons in culture. J Neurosci 17:8955-8963.
    • (1997) J Neurosci , vol.17 , pp. 8955-8963
    • Jareb, M.1    Banker, G.2
  • 28
    • 17844390615 scopus 로고    scopus 로고
    • Axon formation: Fate versus growth
    • Jiang H, Rao Y (2005) Axon formation: fate versus growth. Nat Neurosci 8:544-546.
    • (2005) Nat Neurosci , vol.8 , pp. 544-546
    • Jiang, H.1    Rao, Y.2
  • 29
    • 11844260672 scopus 로고    scopus 로고
    • Both the establishment and the maintenance of neuronal polarity require active mechanisms: Critical roles of GSK-3beta and its upstream regulators
    • Jiang H, Guo W, Liang X, Rao Y (2005) Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK-3beta and its upstream regulators. Cell 120:123-135.
    • (2005) Cell , vol.120 , pp. 123-135
    • Jiang, H.1    Guo, W.2    Liang, X.3    Rao, Y.4
  • 30
    • 0032519651 scopus 로고    scopus 로고
    • Peripheral axotomy induces long-term c-Jun amino-terminal kinase-1 activation and activator protein-1 binding activity by c-Jun and junD in adult rat dorsal root ganglia in vivo
    • Kenney AM, Kocsis JD (1998) Peripheral axotomy induces long-term c-Jun amino-terminal kinase-1 activation and activator protein-1 binding activity by c-Jun and junD in adult rat dorsal root ganglia in vivo. J Neurosci 18:1318-1328.
    • (1998) J Neurosci , vol.18 , pp. 1318-1328
    • Kenney, A.M.1    Kocsis, J.D.2
  • 31
    • 14544300519 scopus 로고    scopus 로고
    • A positive role of the PI3-K/Akt signaling pathway in PC12 cell differentiation
    • Kim Y, Seger R, Suresh Babu CV, Hwang SY, Yoo YS (2004) A positive role of the PI3-K/Akt signaling pathway in PC12 cell differentiation. Mol Cells 18:353-359.
    • (2004) Mol Cells , vol.18 , pp. 353-359
    • Kim, Y.1    Seger, R.2    Suresh Babu, C.V.3    Hwang, S.Y.4    Yoo, Y.S.5
  • 32
    • 20744459425 scopus 로고    scopus 로고
    • Tubulin and CRMP-2 complex is transported via kinesin-1
    • Kimura T, Watanabe H, Iwamatsu A, Kaibuchi K (2005) Tubulin and CRMP-2 complex is transported via kinesin-1. J Neurochem 93:1371-1382.
    • (2005) J Neurochem , vol.93 , pp. 1371-1382
    • Kimura, T.1    Watanabe, H.2    Iwamatsu, A.3    Kaibuchi, K.4
  • 33
    • 13644267037 scopus 로고    scopus 로고
    • Mammalian SAD kinases are required for neuronal polarization
    • Kishi M, Pan YA, Crump JG, Sanes JR (2005) Mammalian SAD kinases are required for neuronal polarization. Science 307:929-932.
    • (2005) Science , vol.307 , pp. 929-932
    • Kishi, M.1    Pan, Y.A.2    Crump, J.G.3    Sanes, J.R.4
  • 35
    • 0033054085 scopus 로고    scopus 로고
    • Co-expression of c-Jun and ATF-2 characterizes the surviving retinal ganglion cells which maintain axonal connections after partial optic nerve injury
    • Kreutz MR, Bien A, Vorwerk CK, Bockers TM, Seidenbecher CI, Tischmeyer W, Sabel BA (1999) Co-expression of c-Jun and ATF-2 characterizes the surviving retinal ganglion cells which maintain axonal connections after partial optic nerve injury. Brain Res Mol Brain Res 69:232-241.
    • (1999) Brain Res Mol Brain Res , vol.69 , pp. 232-241
    • Kreutz, M.R.1    Bien, A.2    Vorwerk, C.K.3    Bockers, T.M.4    Seidenbecher, C.I.5    Tischmeyer, W.6    Sabel, B.A.7
  • 36
    • 0038034941 scopus 로고    scopus 로고
    • Src-CrkII-C3G-dependent activation of Rap1 switches growth hormone-stimulated p44/42MAPkinase and JNK/SAPK activities
    • Ling L, Zhu T, Lobie PE (2003) Src-CrkII-C3G-dependent activation of Rap1 switches growth hormone-stimulated p44/42MAPkinase and JNK/SAPK activities. J Biol Chem 278:27301-27311.
    • (2003) J Biol Chem , vol.278 , pp. 27301-27311
    • Ling, L.1    Zhu, T.2    Lobie, P.E.3
  • 37
    • 0030840413 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase mediates epidermal growth factor-induced activation of the c-Jun N-terminal kinase signaling pathway
    • Logan SK, Falasca M, Hu P, Schlessinger J (1997) Phosphatidylinositol 3-kinase mediates epidermal growth factor-induced activation of the c-Jun N-terminal kinase signaling pathway. Mol Cell Biol 17:5784-5790.
    • (1997) Mol Cell Biol , vol.17 , pp. 5784-5790
    • Logan, S.K.1    Falasca, M.2    Hu, P.3    Schlessinger, J.4
  • 38
    • 0038004740 scopus 로고    scopus 로고
    • Targeting JNK for therapeutic benefit: From junk to gold?
    • Manning AM, Davis RJ (2003) Targeting JNK for therapeutic benefit: from junk to gold? Nat Rev Drug Discov 2:554-565.
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 554-565
    • Manning, A.M.1    Davis, R.J.2
  • 39
    • 0030703604 scopus 로고    scopus 로고
    • Regulation and function of the JNK subgroup of MAP kinases
    • Minden A, Karin M (1997) Regulation and function of the JNK subgroup of MAP kinases. Biochim Biophys Acta 1333:F85-F104.
    • (1997) Biochim Biophys Acta , vol.1333
    • Minden, A.1    Karin, M.2
  • 41
    • 0344393408 scopus 로고    scopus 로고
    • Regulation of MAP kinase signaling modules by scaffold proteins in mammals
    • Morrison DK, Davis RJ (2003) Regulation of MAP kinase signaling modules by scaffold proteins in mammals. Annu Rev Cell Dev Biol 19:91-118.
    • (2003) Annu Rev Cell Dev Biol , vol.19 , pp. 91-118
    • Morrison, D.K.1    Davis, R.J.2
  • 42
    • 0141656303 scopus 로고    scopus 로고
    • Microtubules provide directional cues for polarized axonal transport through interaction with kinesin motor head
    • Nakata T, Hirokawa N (2003) Microtubules provide directional cues for polarized axonal transport through interaction with kinesin motor head. J Cell Biol 162:1045-1055.
    • (2003) J Cell Biol , vol.162 , pp. 1045-1055
    • Nakata, T.1    Hirokawa, N.2
  • 43
    • 0034067992 scopus 로고    scopus 로고
    • Phosphorylation sites on tau identified by nanoelectrospray mass spectrometry: Differences in vitro between the mitogen-activated protein kinases ERK2, c-Jun N-terminal kinase and P38, and glycogen synthase kinase-3beta
    • Reynolds CH, Betts JC, Blackstock WP, Nebreda AR, Anderton BH (2000) Phosphorylation sites on tau identified by nanoelectrospray mass spectrometry: differences in vitro between the mitogen-activated protein kinases ERK2, c-Jun N-terminal kinase and P38, and glycogen synthase kinase-3beta. J Neurochem 74:1587-1595.
    • (2000) J Neurochem , vol.74 , pp. 1587-1595
    • Reynolds, C.H.1    Betts, J.C.2    Blackstock, W.P.3    Nebreda, A.R.4    Anderton, B.H.5
  • 44
    • 0030571014 scopus 로고    scopus 로고
    • Changes in the expression of transcription factors ATF-2 and Fra-2 after axotomy and during regeneration in rat retinal ganglion cells
    • Robinson GA (1996) Changes in the expression of transcription factors ATF-2 and Fra-2 after axotomy and during regeneration in rat retinal ganglion cells. Brain Res Mol Brain Res 41:57-64.
    • (1996) Brain Res Mol Brain Res , vol.41 , pp. 57-64
    • Robinson, G.A.1
  • 45
    • 0032724021 scopus 로고    scopus 로고
    • Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2
    • Sabapathy K, Jochum W, Hochedlinger K, Chang L, Karin M, Wagner EF (1999) Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2. Mech Dev 89:115-124.
    • (1999) Mech Dev , vol.89 , pp. 115-124
    • Sabapathy, K.1    Jochum, W.2    Hochedlinger, K.3    Chang, L.4    Karin, M.5    Wagner, E.F.6
  • 46
    • 4344594485 scopus 로고    scopus 로고
    • The sequential activity of the GT-Pases Rap1B and Cdc42 determines neuronal polarity
    • Schwamborn JC, Püschel AW (2004) The sequential activity of the GT-Pases Rap1B and Cdc42 determines neuronal polarity. Nat Neurosci 7:923-929.
    • (2004) Nat Neurosci , vol.7 , pp. 923-929
    • Schwamborn, J.C.1    Püschel, A.W.2
  • 47
    • 11144267737 scopus 로고    scopus 로고
    • Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein
    • Shaner NC, Campbell RE, Steinbach PA, Giepmans BN, Palmer AE, Tsien RY (2004) Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein. Nat Biotechnol 22:1567-1572.
    • (2004) Nat Biotechnol , vol.22 , pp. 1567-1572
    • Shaner, N.C.1    Campbell, R.E.2    Steinbach, P.A.3    Giepmans, B.N.4    Palmer, A.E.5    Tsien, R.Y.6
  • 48
    • 0037428076 scopus 로고    scopus 로고
    • Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity
    • Shi SH, Jan LY, Jan YN (2003) Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity. Cell 112:63-75.
    • (2003) Cell , vol.112 , pp. 63-75
    • Shi, S.H.1    Jan, L.Y.2    Jan, Y.N.3
  • 49
    • 0029030855 scopus 로고
    • ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents
    • van Dam H, Wilhelm D, Herr I, Steffen A, Herrlich P, Angel P (1995) ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents. EMBO J 14:1798-1811.
    • (1995) EMBO J , vol.14 , pp. 1798-1811
    • Van Dam, H.1    Wilhelm, D.2    Herr, I.3    Steffen, A.4    Herrlich, P.5    Angel, P.6
  • 50
    • 0037205044 scopus 로고    scopus 로고
    • Signaling pathways for PC12 cell differentiation: Making the right connections
    • Vaudry D, Stork PJ, Lazarovici P, Eiden LE (2002) Signaling pathways for PC12 cell differentiation: making the right connections. Science 296:1648-1649.
    • (2002) Science , vol.296 , pp. 1648-1649
    • Vaudry, D.1    Stork, P.J.2    Lazarovici, P.3    Eiden, L.E.4
  • 52
    • 0032508714 scopus 로고    scopus 로고
    • A mammalian scaffold complex that selectively mediates MAP kinase activation
    • Whitmarsh AJ, Cavanagh J, Tournier C, Yasuda J, Davis RJ (1998) A mammalian scaffold complex that selectively mediates MAP kinase activation. Science 281:1671-1674.
    • (1998) Science , vol.281 , pp. 1671-1674
    • Whitmarsh, A.J.1    Cavanagh, J.2    Tournier, C.3    Yasuda, J.4    Davis, R.J.5
  • 53
    • 19944381540 scopus 로고    scopus 로고
    • Polarity proteins in axon specification and synaptogenesis
    • Wiggin GR, Fawcett JP, Pawson T (2005) Polarity proteins in axon specification and synaptogenesis. Dev Cell 8:803-816.
    • (2005) Dev Cell , vol.8 , pp. 803-816
    • Wiggin, G.R.1    Fawcett, J.P.2    Pawson, T.3
  • 54
    • 0442276481 scopus 로고    scopus 로고
    • The control of cell motility and epithelial morphogenesis by Jun kinases
    • Xia Y, Karin M (2004) The control of cell motility and epithelial morphogenesis by Jun kinases. Trends Cell Biol 14:94-101.
    • (2004) Trends Cell Biol , vol.14 , pp. 94-101
    • Xia, Y.1    Karin, M.2
  • 55
    • 0141432134 scopus 로고    scopus 로고
    • Differential roles of ERK and JNK in early and late stages of neuritogenesis: A study in a novel PC12 model system
    • Xiao J, Liu Y (2003) Differential roles of ERK and JNK in early and late stages of neuritogenesis: a study in a novel PC12 model system. J Neurochem 86:1516-1523.
    • (2003) J Neurochem , vol.86 , pp. 1516-1523
    • Xiao, J.1    Liu, Y.2
  • 56
    • 0030835893 scopus 로고    scopus 로고
    • Specific activation of a c-Jun NH2-terminal kinase isoform and induction of neurite outgrowth in PC-12 cells by staurosporine
    • Yao R, Yoshihara M, Osada H (1997) Specific activation of a c-Jun NH2-terminal kinase isoform and induction of neurite outgrowth in PC-12 cells by staurosporine. J Biol Chem 272:18261-18266.
    • (1997) J Biol Chem , vol.272 , pp. 18261-18266
    • Yao, R.1    Yoshihara, M.2    Osada, H.3
  • 57
    • 3142712947 scopus 로고    scopus 로고
    • Phosphorylation of microtubule-associated protein tau by isoforms of c-Jun N-terminal kinase (JNK)
    • Yoshida H, Hastie CJ, McLauchlan H, Cohen P, Goedert M (2004) Phosphorylation of microtubule-associated protein tau by isoforms of c-Jun N-terminal kinase (JNK). J Neurochem 90:352-358.
    • (2004) J Neurochem , vol.90 , pp. 352-358
    • Yoshida, H.1    Hastie, C.J.2    McLauchlan, H.3    Cohen, P.4    Goedert, M.5
  • 60
    • 0032831780 scopus 로고    scopus 로고
    • The JNKK2-JNK1 fusion protein acts as a constitutively active c-Jun kinase that stimulates c-Jun transcription activity
    • Zheng C, Xiang J, Hunter T, Lin A (1999) The JNKK2-JNK1 fusion protein acts as a constitutively active c-Jun kinase that stimulates c-Jun transcription activity. J Biol Chem 274:28966-28971.
    • (1999) J Biol Chem , vol.274 , pp. 28966-28971
    • Zheng, C.1    Xiang, J.2    Hunter, T.3    Lin, A.4


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