-
1
-
-
24944489213
-
Genetic insights in the pathogenesis of T-cell acute lymphoblastic leukemia
-
De Keersmaecker K, Marynen P, Cools J. Genetic insights in the pathogenesis of T-cell acute lymphoblastic leukemia. Haematologica. 2005;90(8):1116-1127. (Pubitemid 41323512)
-
(2005)
Haematologica
, vol.90
, Issue.8
, pp. 1116-1127
-
-
De Keersmaecker, K.1
Marynen, P.2
Cools, J.3
-
2
-
-
22044457152
-
HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL)
-
DOI 10.1182/blood-2004-10-3900
-
Soulier J, Clappier E, Cayuela JM, et al. HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (TALL). Blood. 2005;106(1):274-286. (Pubitemid 40967203)
-
(2005)
Blood
, vol.106
, Issue.1
, pp. 274-286
-
-
Soulier, J.1
Clappier, E.2
Cayuela, J.-M.3
Regnault, A.4
Garcia-Peydro, M.5
Dombret, H.6
Baruchel, A.7
Toribio, M.-L.8
Sigaux, F.9
-
3
-
-
17144474314
-
Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia
-
DOI 10.1016/S1535-6108(02)00018-1
-
Ferrando AA, Neuberg DS, Staunton J, et al. Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia. Cancer Cell. 2002;1(1):75-87. (Pubitemid 41039178)
-
(2002)
Cancer Cell
, vol.1
, Issue.1
, pp. 75-87
-
-
Ferrando, A.A.1
Neuberg, D.S.2
Staunton, J.3
Loh, M.L.4
Huard, C.5
Raimondi, S.C.6
Behm, F.G.7
Pui, C.-H.8
Downing, J.R.9
Gilliland, D.G.10
Lander, E.S.11
Golub, T.R.12
Look, A.T.13
-
4
-
-
70149087158
-
High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia
-
Gutierrez A, Sanda T, Grebliunaite R, et al. High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia. Blood. 2009;114(3):647-650.
-
(2009)
Blood
, vol.114
, Issue.3
, pp. 647-650
-
-
Gutierrez, A.1
Sanda, T.2
Grebliunaite, R.3
-
5
-
-
77951015381
-
Inactivation of LEF1 in T-cell acute lymphoblastic leukemia
-
Gutierrez A, Sanda T, Ma W, et al. Inactivation of LEF1 in T-cell acute lymphoblastic leukemia. Blood. 2010;115(14):2845-2851.
-
(2010)
Blood
, vol.115
, Issue.14
, pp. 2845-2851
-
-
Gutierrez, A.1
Sanda, T.2
Ma, W.3
-
6
-
-
5044225888
-
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
-
DOI 10.1126/science.1102160
-
Weng AP, Ferrando AA, Lee W, et al. Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science. 2004;306(5694):269-271. (Pubitemid 39336870)
-
(2004)
Science
, vol.306
, Issue.5694
, pp. 269-271
-
-
Weng, A.P.1
Ferrando, A.A.2
Lee, W.3
Morris IV, J.P.4
Silverman, L.B.5
Sanchez-Irizarry, C.6
Blacklow, S.C.7
Look, A.T.8
Aster, J.C.9
-
7
-
-
65449135968
-
NOTCH1/FBXW7 mutation identifies a large subgroup with favorable outcome in adult T-cell acute lymphoblastic leukemia (T-ALL): A Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL) study
-
Asnafi V, Buzyn A, Le Noir S, et al. NOTCH1/FBXW7 mutation identifies a large subgroup with favorable outcome in adult T-cell acute lymphoblastic leukemia (T-ALL): a Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL) study. Blood. 2009;113(17):3918-3924.
-
(2009)
Blood
, vol.113
, Issue.17
, pp. 3918-3924
-
-
Asnafi, V.1
Buzyn, A.2
Le Noir, S.3
-
8
-
-
0028353897
-
Oncogenic activation of the Lck protein accompanies translocation of the LCK gene in the human HSB2 T-cell leukemia
-
Wright DD, Sefton BM, Kamps MP. Oncogenic activation of the Lck protein accompanies translocation of the LCK gene in the human HSB2 T-cell leukemia. Mol Cell Biol. 1994;14(4):2429-2437. (Pubitemid 24108225)
-
(1994)
Molecular and Cellular Biology
, vol.14
, Issue.4
, pp. 2429-2437
-
-
Wright, D.D.1
Sefton, B.M.2
Kamps, M.P.3
-
9
-
-
72249120192
-
JAK1 mutations are not frequent events in adult T-ALL: A GRAALL study
-
Asnafi V, Le Noir S, Lhermitte L, et al. JAK1 mutations are not frequent events in adult T-ALL: a GRAALL study. Br J Haematol. 2010;148(1):178-179.
-
(2010)
Br J Haematol
, vol.148
, Issue.1
, pp. 178-179
-
-
Asnafi, V.1
Le Noir, S.2
Lhermitte, L.3
-
10
-
-
42249091014
-
Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia
-
DOI 10.1084/jem.20072182
-
Flex E, Petrangeli V, Stella L, et al. Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia. J Exp Med. 2008;205(4):751-758. (Pubitemid 351549874)
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.4
, pp. 751-758
-
-
Flex, E.1
Petrangeli, V.2
Stella, L.3
Chiaretti, S.4
Hornakova, T.5
Knoops, L.6
Ariola, C.7
Fodale, V.8
Clappier, E.9
Paoloni, F.10
Martinelli, S.11
Fragale, A.12
Sanchez, M.13
Tavolaro, S.14
Messina, M.15
Cazzaniga, G.16
Camera, A.17
Pizzolo, G.18
Tornesello, A.19
Vignetti, M.20
Battistini, A.21
Cave, H.22
Gelb, B.D.23
Renauld, J.-C.24
Biondi, A.25
Constantinescu, S.N.26
Foa, R.27
Tartaglia, M.28
more..
-
11
-
-
77949369691
-
ABL1 rearrangements in T-cell acute lymphoblastic leukemia
-
Hagemeijer A, Graux C. ABL1 rearrangements in T-cell acute lymphoblastic leukemia. Genes Chromosomes Cancer. 2010;49(4):299-308.
-
(2010)
Genes Chromosomes Cancer
, vol.49
, Issue.4
, pp. 299-308
-
-
Hagemeijer, A.1
Graux, C.2
-
12
-
-
0027938776
-
Candidate tumor-suppressor genes MTS1 (p16INK4A) and MTS2 (p15INK4B) display frequent homozygous deletions in primary cells from T- But not from B-cell lineage acute lymphoblastic leukemias
-
Hebert J, Cayuela JM, Berkeley J, Sigaux F. Candidate tumor-suppressor genes MTS1 (p16INK4A) and MTS2 (p15INK4B) display frequent homozygous deletions in primary cells from T- but not from B-cell lineage acute lymphoblastic leukemias. Blood. 1994;84(12):4038-4044.
-
(1994)
Blood
, vol.84
, Issue.12
, pp. 4038-4044
-
-
Hebert, J.1
Cayuela, J.M.2
Berkeley, J.3
Sigaux, F.4
-
13
-
-
6944252248
-
Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia
-
DOI 10.1038/ng1425
-
Graux C, Cools J, Melotte C, et al. Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia. Nat Genet. 2004;36(10):1084-1089. (Pubitemid 41184470)
-
(2004)
Nature Genetics
, vol.36
, Issue.10
, pp. 1084-1089
-
-
Graux, C.1
Cools, J.2
Melotte, C.3
Quentmeier, H.4
Ferrando, A.5
Levine, R.6
Vermeesch, J.R.7
Stul, M.8
Dutta, B.9
Boeckx, N.10
Bosly, A.11
Heimann, P.12
Uyttebroeck, A.13
Mentens, N.14
Somers, R.15
MacLeod, R.A.R.16
Drexler, H.G.17
Look, A.T.18
Gilliland, D.G.19
Michaux, L.20
Vandenberghe, P.21
Wlodarska, I.22
Marynen, P.23
Hagemeijer, A.24
more..
-
14
-
-
52449119447
-
Somatic mutations of JAK1 and JAK3 in acute leukemias and solid cancers
-
Jeong EG, Kim MS, Nam HK, et al. Somatic mutations of JAK1 and JAK3 in acute leukemias and solid cancers. Clin Cancer Res. 2008;14(12):3716-3721.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.12
, pp. 3716-3721
-
-
Jeong, E.G.1
Kim, M.S.2
Nam, H.K.3
-
15
-
-
77952887619
-
Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia
-
Kleppe M, Lahortiga I, El Chaar T, et al. Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia. Nat Genet. 2010;42(6):530-535.
-
(2010)
Nat Genet
, vol.42
, Issue.6
, pp. 530-535
-
-
Kleppe, M.1
Lahortiga, I.2
El Chaar, T.3
-
16
-
-
0036006288
-
The T cell protein tyrosine phosphatase is a negative regulator of Janus family kinases 1 and 3
-
DOI 10.1016/S0960-9822(02)00697-8, PII S0960982202006978
-
Simoncic PD, Lee-Loy A, Barber DL, Tremblay ML, McGlade CJ. The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3. Curr Biol. 2002;12(6):446-453. (Pubitemid 34248890)
-
(2002)
Current Biology
, vol.12
, Issue.6
, pp. 446-453
-
-
Simoncic, P.D.1
Lee-Loy, A.2
Barber, D.L.3
Tremblay, M.L.4
McGlade, C.J.5
-
17
-
-
0036318564
-
Identification of a nuclear Stat1 protein tyrosine phosphatase
-
ten Hoeve J, de Jesus Ibarra-Sanchez M, Fu Y, et al. Identification of a nuclear Stat1 protein tyrosine phosphatase. Mol Cell Biol. 2002;22(16):5662- 5668.
-
(2002)
Mol Cell Biol
, vol.22
, Issue.16
, pp. 5662-5668
-
-
Ten Hoeve, J.1
De Jesus Ibarra-Sanchez, M.2
Fu, Y.3
-
18
-
-
33947221062
-
T-cell protein tyrosine phosphatase, distinctively expressed in activated-B-cell-like diffuse large B-cell lymphomas, is the nuclear phosphatase of STAT6
-
DOI 10.1128/MCB.01234-06
-
Lu X, Chen J, Sasmono RT, et al. T-cell protein tyrosine phosphatase, distinctively expressed in activated-B-cell-like diffuse large B-cell lymphomas, is the nuclear phosphatase of STAT6. Mol Cell Biol. 2007;27(6):2166-2179. (Pubitemid 46418473)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.6
, pp. 2166-2179
-
-
Lu, X.1
Chen, J.2
Sasmono, R.T.3
Hsi, E.D.4
Sarosiek, K.A.5
Tiganis, T.6
Lossos, I.S.7
-
19
-
-
77951437714
-
ALL-associated JAK1 mutations confer hypersensitivity to the antiproliferative effect of type I interferon
-
Hornakova T, Chiaretti S, Lemaire MM, et al. ALL-associated JAK1 mutations confer hypersensitivity to the antiproliferative effect of type I interferon. Blood. 2010;115(16):3287-3295.
-
(2010)
Blood
, vol.115
, Issue.16
, pp. 3287-3295
-
-
Hornakova, T.1
Chiaretti, S.2
Lemaire, M.M.3
-
20
-
-
20444378917
-
Fusion of EML1 to ABL1 in T-cell acute lymphoblastic leukemia with cryptic t(9;14)(q34;q32)
-
DOI 10.1182/blood-2004-12-4897
-
De Keersmaecker K, Graux C, Odero MD, et al. Fusion of EML1 to ABL1 in T-cell acute lymphoblastic leukemia with cryptic t(9;14)(q34;q32). Blood. 2005;105(12):4849-4852. (Pubitemid 40807313)
-
(2005)
Blood
, vol.105
, Issue.12
, pp. 4849-4852
-
-
De Keersmaecker, K.1
Graux, C.2
Odero, M.D.3
Mentens, N.4
Somers, R.5
Maertens, J.6
Wlodarska, I.7
Vandenberghe, P.8
Hagemeijer, A.9
Marynen, P.10
Cools, J.11
-
21
-
-
79955741414
-
MOHITO, a novel mouse cytokine-dependent T-cell line, enables studies of oncogenic signaling in the T-cell context
-
Kleppe M, Mentens N, Tousseyn T, Wlodarska I, Cools J. MOHITO, a novel mouse cytokine-dependent T-cell line, enables studies of oncogenic signaling in the T-cell context. Haematologica. 2011;96(5):779-783.
-
(2011)
Haematologica
, vol.96
, Issue.5
, pp. 779-783
-
-
Kleppe, M.1
Mentens, N.2
Tousseyn, T.3
Wlodarska, I.4
Cools, J.5
-
22
-
-
33845360035
-
Ba/F3 cells and their use in kinase drug discovery
-
DOI 10.1097/CCO.0b013e328011a25f, PII 0000162220070100000011
-
Warmuth M, Kim S, Gu XJ, Xia G, Adrian F. Ba/F3 cells and their use in kinase drug discovery. Curr Opin Oncol. 2007;19(1):55-60. (Pubitemid 44885601)
-
(2007)
Current Opinion in Oncology
, vol.19
, Issue.1
, pp. 55-60
-
-
Warmuth, M.1
Kim, S.2
Gu, X.-J.3
Xia, G.4
Adrian, F.5
-
23
-
-
43049126784
-
PTP1B and TC-PTP: Regulators of transformation and tumorigenesis
-
Stuible M, Doody KM, Tremblay ML. PTP1B and TC-PTP: regulators of transformation and tumorigenesis. Cancer Metastasis Rev. 2008;27(2):215-230.
-
(2008)
Cancer Metastasis Rev
, vol.27
, Issue.2
, pp. 215-230
-
-
Stuible, M.1
Doody, K.M.2
Tremblay, M.L.3
-
24
-
-
30444437486
-
Treatment of acute lymphoblastic leukemia
-
DOI 10.1056/NEJMra052603
-
Pui CH, Evans WE. Treatment of acute lymphoblastic leukemia. N Engl J Med. 2006;354(2):166-178. (Pubitemid 43076714)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.2
, pp. 166-178
-
-
Pui, C.-H.1
Evans, W.E.2
-
25
-
-
38349053791
-
JAK2 inhibitor therapy in myeloproliferative disorders: Rationale, preclinical studies and ongoing clinical trials
-
Pardanani A. JAK2 inhibitor therapy in myeloproliferative disorders: rationale, preclinical studies and ongoing clinical trials. Leukemia. 2008;22(1):23-30.
-
(2008)
Leukemia
, vol.22
, Issue.1
, pp. 23-30
-
-
Pardanani, A.1
-
26
-
-
77953208379
-
Ruxolitinib, a selective JAK1 and JAK2 inhibitor for the treatment of myeloproliferative neoplasms and psoriasis
-
Mesa RA. Ruxolitinib, a selective JAK1 and JAK2 inhibitor for the treatment of myeloproliferative neoplasms and psoriasis. IDrugs. 2010;13(6):394-403.
-
(2010)
IDrugs
, vol.13
, Issue.6
, pp. 394-403
-
-
Mesa, R.A.1
|