Cytokine Release

Mechanical Ventilation: Clinical Applications and Pathophysiology

Volumn , Issue , 2008, Pages 216-224

  Haitsma, Jack J ^a,b   Schultz, Marcus J ^a   Slutsky, Arthur S ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b ST MICHAEL'S HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 79959823476     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-7216-0186-1.50023-5     Document Type: Chapter

References (80)

1. Bauer TT, Monton C, Torres A, et al. Comparison of systemic cytokine levels in patients with acute respiratory distress syndrome, severe pneumonia, and controls. Thorax 2000, 55:46-52.
2. Meduri GU Host defense response and outcome in ARDS. Chest 1997, 112:1154-1158.
3. Meduri GU, Kohler G, Headley S, et al. Inflammatory cytokines in the BAL of patients with ARDS: Persistent elevation over time predicts poor outcome. Chest 1995, 108:1303-1314.
4. Park WY, Goodman RB, Steinberg KP, et al. Cytokine balance in the lungs of patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 2001, 164:1896-1903.
5. Ranieri VM, Giunta F, Suter PM, et al. Mechanical ventilation as a mediator of multisystem organ failure in acute respiratory distress syndrome. JAMA 2000, 284:43-44.
6. Ranieri VM, Suter PM, Tortorella C, et al. Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: A randomized controlled trial. JAMA 1999, 282:54-61.
7. Idell S Coagulation, fibrinolysis, and fibrin deposition in acute lung injury. Crit Care Med 2003, 31:S213-220.
8. Levi M, Schultz MJ, Rijneveld AW, et al. Bronchoalveolar coagulation and fibrinolysis in endotoxemia and pneumonia. Crit Care Med 2003, 31:S238-S242.
9. Schultz MJ, Levi M, van der Poll T Anticoagulant therapy for acute lung injury or pneumonia. Curr Drug Targets 2003, 4:315-321.
10. Matthay MA, Zimmerman GA Acute lung injury and the acute respiratory distress syndrome: Four decades of inquiry into pathogenesis and rational management. Am J Respir Cell Mol Biol 2005, 33:319-327.
11. Martin TR Lung cytokines and ARDS: Roger S. Mitchell Lecture. Chest 1999, 116:2S-8S.
12. Park DR, Thomsen AR, Frevert CW, et al. Fas (CD95) induces proinflammatory cytokine responses by human monocytes and monocyte-derived macrophages. J Immunol 2003, 170:6209-6216.
13. Cox G, Crossley J, Xing Z Macrophage engulfment of apoptotic neutrophils contributes to the resolution of acute pulmonary inflammation in vivo. Am J Respir Cell Mol Biol 1995, 12:232-237.
14. Hussain N, Wu F, Zhu L, et al. Neutrophil apoptosis during the development and resolution of oleic acid-induced acute lung injury in the rat. Am J Respir Cell Mol Biol 1998, 19:867-874.
15. Li X, Shu R, Filippatos G, et al. Apoptosis in lung injury and remodeling. J Appl Physiol 2004, 97:1535-1542.
16. Matute-Bello G, Liles WC, Radella F, et al. Modulation of neutrophil apoptosis by granulocyte colony-stimulating factor and granulocyte/macrophage colony-stimulating factor during the course of acute respiratory distress syndrome. Crit Care Med 2000, 28:1-7.
17. Matute-Bello G, Liles WC, Steinberg KP, et al. Soluble Fas ligand induces epithelial cell apoptosis in humans with acute lung injury (ARDS). J Immunol 1999, 163:2217-2225.
18. Matute-Bello G, Martin TR Science review: Apoptosis in acute lung injury. Crit Care 2003, 7:355-358.
19. Teder P, Vandivier RW, Jiang D, et al. Resolution of lung inflammation by CD44. Science 2002, 296:155-158.
20. McKee CM, Penno MB, Cowman M, et al. Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages: The role of HA size and CD44. J Clin Invest 1996, 98:2403-2413.
21. Tremblay L, Valenza F, Ribeiro SP, et al. Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model. J Clin Invest 1997, 99:944-952.
22. Whitehead TC, Zhang H, Mullen B, et al. Effect of mechanical ventilation on cytokine response to intratracheal lipopolysaccharide. Anesthesiology 2004, 101:52-58.
23. Tremblay LN, Miatto D, Hamid Q, et al. Injurious ventilation induces widespread pulmonary epithelial expression of tumor necrosis factor-alpha and interleukin-6 messenger RNA. Crit Care Med 2002, 30:1693-1700.
24. Ricard JD, Dreyfuss D, Saumon G Production of inflammatory cytokines in ventilator-induced lung injury: A reappraisal. Am J Respir Crit Care Med 2001, 163:1176-1180.
25. Verbrugge SJ, Uhlig S, Neggers SJ, et al. Different ventilation strategies affect lung function but do not increase tumor necrosis factor-alpha and prostacyclin production in lavaged rat lungs in vivo. Anesthesiology 1999, 91:1834-1843.
26. Haitsma JJ, Uhlig S, Verbrugge SJ, et al. Injurious ventilation strategies cause systemic release of IL-6 and MIP-2 in rats in vivo. Clin Physiol Funct Imaging 2003, 23:349-353.
27. Chiumello D, Pristine G, Slutsky AS Mechanical ventilation affects local and systemic cytokines in an animal model of acute respiratory distress syndrome. Am J Respir Crit Care Med 1999, 160:109-116.
28. van Kaam AH, Lutter R, Lachmann RA, et al. Effect of ventilation strategy and surfactant on inflammation in experimental pneumonia. Eur Respir J 2005, 26:112-117.
29. Haitsma JJ, Uhlig S, Goggel R, et al. Ventilator-induced lung injury leads to loss of alveolar and systemic compartmentalization of tumor necrosis factor-alpha. Intensive Care Med 2000, 26:1515-1522.
30. Haitsma JJ, Uhlig S, Lachmann U, et al. Exogenous surfactant reduces ventilator-induced decompartmentalization of tumor necrosis factor alpha in absence of positive end-expiratory pressure. Intensive Care Med 2002, 28:1131-1137.
31. Nelson S, Bagby GJ, Bainton BG, et al. Compartmentalization of intraalveolar and systemic lipopolysaccharide-induced tumor necrosis factor and the pulmonary inflammatory response. J Infect Dis 1989, 159:189-194.
32. Tutor JD, Mason CM, Dobard E, et al. Loss of compartmentalization of alveolar tumor necrosis factor after lung injury. Am J Respir Crit Care Med 1994, 149:1107-1111.
33. Pugin J, Verghese G, Widmer MC, et al. The alveolar space is the site of intense inflammatory and profibrotic reactions in the early phase of acute respiratory distress syndrome. Crit Care Med 1999, 27:304-312.
34. Kawano T, Mori S, Cybulsky M, et al. Effect of granulocyte depletion in a ventilated surfactant-depleted lung. J Appl Physiol 1987, 62:27-33.
35. Pugin J, Dunn I, Jolliet P, et al. Activation of human macrophages by mechanical ventilation in vitro. Am J Physiol 1998, 275:L1040-L1050.
36. Vlahakis NE, Schroeder MA, Limper AH, et al. Stretch induces cytokine release by alveolar epithelial cells in vitro. Am J Physiol 1999, 277:L167-L173.
37. Mourgeon E, Isowa N, Keshavjee S, et al. Mechanical stretch stimulates macrophage inflammatory protein-2 secretion from fetal rat lung cells. Am J Physiol 2000, 279:L699-706.
38. Hammerschmidt S, Kuhn H, Grasenack T, et al. Apoptosis and necrosis induced by cyclic mechanical stretching in alveolar type II cells. Am J Respir Cell Mol Biol 2004, 30:396-402.
39. Tschumperlin DJ, Dai G, Maly IV, et al. Mechanotransduction through growth-factor shedding into the extracellular space. Nature 2004, 429:83-86.
40. Dos Santos CC, Slutsky AS Mechanisms of ventilator-induced lung injury: A perspective. J Appl Physiol 2000, 89:1645-1655.
41. Uhlig S Ventilation-induced lung injury and mechanotransduction: Stretching it too far?. Am J Physiol 2002, 282:L892-L896.
42. Liu M, Tanswell AK, Post M Mechanical force-induced signal transduction in lung cells. Am J Physiol 1999, 277:L667-683.
43. Kyriakis JM, Avruch J Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 2001, 81:807-869.
44. Uhlig U, Haitsma JJ, Goldmann T, et al. Ventilation-induced activation of the mitogen-activated protein kinase pathway. Eur Respir J 2002, 20:946-956.
45. Held HD, Boettcher S, Hamann L, et al. Ventilation-induced chemokine and cytokine release is associated with activation of nuclear factor-kappa B and is blocked by steroids. Am J Respir Crit Care Med 2001, 163:711-716.
46. von Bethmann AN, Brasch F, Muller KM, et al. Prolonged hyperventilation is required for release of tumor necrosis factor alpha but not IL-6. Appl Cardiopulm Pathol 1996, 6:171-177.
47. von Bethmann AN, Brasch F, Nusing R, et al. Hyperventilation induces release of cytokines from perfused mouse lung. Am J Respir Crit Care Med 1998, 157:263-272.
48. Chang L, Karin M Mammalian MAP kinase signalling cascades. Nature 2001, 410:37-40.
49. Fan J, Ye RD, Malik AB Transcriptional mechanisms of acute lung injury. Am J Physiol 2001, 281:L1037-1050.
50. Schwartz MD, Moore EE, Moore FA, et al. Nuclear factor-kappa B is activated in alveolar macrophages from patients with acute respiratory distress syndrome. Crit Care Med 1996, 24:1285-1292.
51. Uhlig U, Fehrenbach H, Lachmann RA, et al. Phosphoinositide 3-OH kinase inhibition prevents ventilation-induced lung cell activation. Am J Respir Crit Care Med 2004, 169:201-208.
52. Li LF, Yu L, Quinn DA Ventilation-induced neutrophil infiltration depends on c-Jun N-terminal kinase. Am J Respir Crit Care Med 2004, 169:518-524.
53. Levi M, Ten Cate H Disseminated intravascular coagulation. N Engl J Med 1999, 341:586-592.
54. Fourrier F, Chopin C, Goudemand J, et al. Septic shock, multiple organ failure, and disseminated intravascular coagulation: Compared patterns of antithrombin III, protein C, and protein S deficiencies. Chest 1992, 101:816-823.
55. Levi M, van der Poll T, Buller HR Bidirectional relation between inflammation and coagulation. Circulation 2004, 109:2698-2704.
56. Gunther A, Mosavi P, Heinemann S, et al. Alveolar fibrin formation caused by enhanced procoagulant and depressed fibrinolytic capacities in severe pneumonia: Comparison with the acute respiratory distress syndrome. Am J Respir Crit Care Med 2000, 161:454-462.
57. Idell S, James KK, Levin EG, et al. Local abnormalities in coagulation and fibrinolytic pathways predispose to alveolar fibrin deposition in the adult respiratory distress syndrome. J Clin Invest 1989, 84:695-705.
58. Dahlem P, Bos AP, Haitsma JJ, et al. Alveolar fibrinolytic capacity suppressed by injurious mechanical ventilation. Intensive Care Med 2005, 31:724-732.
59. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000, 342:1301-1308. ARDS Network.
60. Esteban A, Anzueto A, Frutos F, et al. Characteristics and outcomes in adult patients receiving mechanical ventilation: A 28-day international study. JAMA 2002, 287:345-355.
61. Ferring M, Vincent JL Is outcome from ARDS related to the severity of respiratory failure?. Eur Respir J 1997, 10:1297-1300.
62. Slutsky AS, Tremblay LN Multiple system organ failure: Is mechanical ventilation a contributing factor?. Am J Respir Crit Care Med 1998, 157:1721-1725.
63. Tremblay LN, Slutsky AS Ventilator-induced injury: From barotrauma to biotrauma. Proc Assoc Am Physicians 1998, 110:482-488.
64. Zhang H, Downey GP, Suter PM, et al. Conventional mechanical ventilation is associated with bronchoalveolar lavage-induced activation of polymorphonuclear leukocytes: A possible mechanism to explain the systemic consequences of ventilator-induced lung injury in patients with ARDS. Anesthesiology 2002, 97:1426-1433.
65. Parsons PE, Eisner MD, Thompson BT, et al. Lower tidal volume ventilation and plasma cytokine markers of inflammation in patients with acute lung injury. Crit Care Med 2005, 33:1-6. discussion 230-232.
66. Parsons PE, Matthay MA, Ware LB, et al. Elevated plasma levels of soluble TNF receptors are associated with morbidity and mortality in patients with acute lung injury. Am J Physiol 2005, 288:L426-L431.
67. Imai Y, Parodo J, Kajikawa O, et al. Injurious mechanical ventilation and end-organ epithelial cell apoptosis and organ dysfunction in an experimental model of acute respiratory distress syndrome. JAMA 2003, 289:2104-2112.
68. Wardle EN Acute renal failure and multiorgan failure. Nephrol Dial Transplant 1994, 4(Suppl):104-107.
69. Kuiper JW, Groeneveld AB, Slutsky AS, et al. Mechanical ventilation and acute renal failure. Crit Care Med 2005, 33:1408-1415.
70. Gurkan OU, O'Donnell C, Brower R, et al. Differential effects of mechanical ventilatory strategy on lung injury and systemic organ inflammation in mice. Am J Physiol 2003, 285:L710-718.
71. Vreugdenhil HA, Heijnen CJ, Plotz FB, et al. Mechanical ventilation of healthy rats suppresses peripheral immune function. Eur Respir J 2004, 23:122-128.
72. Donnelly SC, Strieter RM, Kunkel SL, et al. Interleukin-8 and development of adult respiratory distress syndrome in at-risk patient groups. Lancet 1993, 341:643-647.
73. Chollet-Martin S, Montravers P, Gibert C, et al. High levels of interleukin-8 in the blood and alveolar spaces of patients with pneumonia and adult respiratory distress syndrome. Infect Immun 1993, 61:4553-4559.
74. Goodman RB, Strieter RM, Martin DP, et al. Inflammatory cytokines in patients with persistence of the acute respiratory distress syndrome. Am J Respir Crit Care Med 1996, 154:602-611.
75. Headley AS, Tolley E, Meduri GU Infections and the inflammatory response in acute respiratory distress syndrome. Chest 1997, 111:1306-1321.
76. Roumen RM, Hendriks T, van der Ven-Jongekrijg J, et al. Cytokine patterns in patients after major vascular surgery, hemorrhagic shock, and severe blunt trauma: Relation with subsequent adult respiratory distress syndrome and multiple organ failure. Ann Surg 1993, 218:769-776.
77. Dehoux MS, Boutten A, Ostinelli J, et al. Compartmentalized cytokine production within the human lung in unilateral pneumonia. Am J Respir Crit Care Med 1994, 150:710-716.
78. Wrigge H, Zinserling J, Stuber F, et al. Effects of mechanical ventilation on release of cytokines into systemic circulation in patients with normal pulmonary function. Anesthesiology 2000, 93:1413-1417.
79. Wrigge H, Uhlig U, Baumgarten G, et al. Mechanical ventilation strategies and inflammatory responses to cardiac surgery: A prospective randomized clinical trial. Intensive Care Med 2005, 31:1379-1387.
80. Stüber F, Wrigge H, Schroeder S, et al. Kinetic and reversibility of mechanical ventilation-associated pulmonary and systemic inflammatory response in patients with acute lung injury. Intensive Care Med 2002, 28:834-841.