Ventilation-induced Neutrophil Infiltration Depends on c-Jun N-Terminal Kinase

American Journal of Respiratory and Critical Care Medicine

Volumn 169, Issue 4, 2004, Pages 518-524

  Li, Li Fu ^b   Yu, Lunyin ^b   Quinn, Deborah A ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b NONE

Author keywords

Chemokine; Lung stretch; Mitogen activated protein kinase

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; MACROPHAGE INFLAMMATORY PROTEIN 2; MESSENGER RNA; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; KNOCKOUT MOUSE; LUNG; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0442329090     PISSN: 00030805     EISSN: None     Source Type: Journal    
DOI: 10.1164/rccm.200305-660oc     Document Type: Article

References (44)

1. Maunder RJ, Shuman WP, McHugh JW, Marglin SI, Butler J. Preservation of normal lung regions in the adult respiratory distress syndrome: analysis by computed tomography. JAMA 1986;255:2463-2465.
2. Dreyfuss D, Saumon G. Ventilator-induced lung injury: lessons from experimental studies. Am J Respir Crit Care Med 1998;157:294-323.
3. Tremblay L, Valenza F, Ribeiro SP, Li J, Slutsky AS. Injurious ventilatory strategies increase cytokines and c-fos mRNA expression in an isolated rat lung model. J Clin Invest 1997;99:944-952.
4. Quinn DA, Moufarrej RK, Volokhov A, Hales CA. Interactions of lung stretch, hyperoxia, and MIP-2 production in ventilator-induced lung injury. J Appl Physiol 2002;93:517-525.
5. Hales CA, Du HK, Volokhov A, Mourfarrej R, Quinn DA. Aquaporin channels may modulate ventilator-induced lung injury. Respir Physiol 2001;124:159-166.
6. Choi WI, Quinn DA, Park KM, Moufarrej RK, Jafari B, Syrkina O, Bonventre JV, Hales CA. Systemic microvascular leak in an in vivo rat model of ventilator-induced lung injury. Am J Respir Crit Care Med 2003;167:1627-1632.
7. The Acute Respiratory Distress Syndrome Network. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000;342:1301-1308.
8. Ranieri VM, Suter PM, Tortorella C, DeTullio R, Dayer JM, Brienza A, Bruno F, Slutsky AS. Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome. JAMA 1999;282:54-61.
9. Held HD, Boettcher S, Hamann L, Uhlig S. Ventilation-induced chemokine and cytokine release is associated with activation of nuclear factor-κB and is blocked by steroids. Am J Respir Crit Care Med 2001;163:711-716.
10. Belperio JA, Keane MP, Burdick MD, Londhe V, Xue YY, Li K, Phillips RJ, Strieter RM. Critical role for CXCR2 and CXCR2 ligands during the pathogenesis of ventilator-induced lung injury. J Clin Invest 2002;110:1703-1716.
11. Ingram AJ, Ly H, Thai K, Kang M, Scholey JW. Activation of mesangial cell signaling cascades in response to mechanical strain. Kidney Int 1999;55:476-485.
12. Li C, Hu Y, Mayr M, Xu Q. Cyclic strain stress-induced mitogen-activated protein kinase (MAPK) phosphatase 1 expression in vascular smooth muscle cells is regulated by Ras/Rac-MAPK pathways. J Biol Chem 1999;274:25273-25280.
13. 2-terminal kinase activation by mechanical stretch is integrin-dependent and matrix-specific in rat cardiac fibroblasts. J Clin Invest 1998;101:301-310.
14. Seko Y, Takhashi N, Tobe K, Kadowaki T, Yazaki Y. Pulsatile stretch activates mitogen-activated protein kinase (MAPK) family members and focal adhesion kinase (p125(FAK)) in cultured rat cardiac myocytes. Biochem Biophys Res Commun 1999;259:8-14.
15. Force T, Pombo CM, Avruch JA, Bonventre JV, Kyriakis JM. Stress activated protein kinases in cardiovascular diseases. Circ Res 1996;78:947-953.
16. Oudin S, Pugin J. Role of MAP kinase activation in interleukin-8 production by human BEAS-2B bronchial epithelial cells submitted to cyclic stretch. Am J Respir Cell Mol Biol 2002;27:107-114.
17. Uhlig U, Haitsma JJ, Goldmann T, Poelma DL, Lachmann B, Uhlig S. Ventilation-induced activation of the mitogen-activated protein kinase pathway. Eur Respir J 2002;20:946-956.
18. Copland IB, Kavanagh BP, Engelberts D, McKerlie C, Belik J, Post M. Early changes in lung gene expression due to high tidal volume. Am J Respir Crit Care Med 2003;168:1051-1059.
19. Li LF, Ouyang B, Choukroun G, Matyal R, Mascarenhas M, Jafari B, Bonventre JV, Force T, Quinn DA. Stretch-induced IL-8 depends on c-Jun-terminal and nuclear factor-κB-inducing kinases. Am J Physiol Lung Cell Mol Physiol 2003;285:L464-L475.
20. Dong C, Yang DD, Wysk M, Whitmarsh AJ, Davis RJ, Flavell RA. Defective T cell differentiation in the absence of Jnk1. Science 1998;282:2092-2095.
21. + T cells to Th1 cells requires MAP kinase JNK2. Immunity 1998;9:575-585.
22. Davis RJ. Signal transduction by the JNK group of MAP kinases. Cell 2000;103:239-252.
23. Mikawa K, Maekawa N, Nishina K, Takao Y, Yaku H, Obara H. Effect of lidocaine pretreatment on endotoxin-induced lung injury in rabbits. Anesthesiology 1994;81:689-699.
24. Bennet BL, Sasaki DT, Murray BW, O'Leary EC, Sakata ST, Xu W, Leisten JC, Motiwala A, Pierce S, Satoh Y, et al. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc Natl Acad Sci USA 2001;98:13681-13686.
25. Han Z, Boyle DL, Chang L, Bennett B, Karin M, Yang L, Manning AM, Firestein GS. c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis. J Clin Invest 2001;108:73-81.
26. Holtmann H, Winzen R, Holland P, Eickemeier S, Hoffmann E, Wallach D, Malinin NL, Cooper JA, Resch K, Kracht M. Induction of interleukin-8 synthesis integrates effects on transcription and mRNA degradation from at least three different cytokine-or stress-activated signal transduction pathways. Mol Cell Biol 1999;19:6742-6753.
27. Winzen R, Kracht M, Ritter B, Wilhelm A, Chen CY, Shyu AB, Muller M, Gaestel M, Resch K, Holtmann H. The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism. EMBO J 1999;18:4969-4980.
28. Morse D, Otterbein LE, Watkins S, Alber S, Zhou Z, Flavell RA, Davis RJ, Choi AMK. Deficiency in the c-Jun NH2-terminal kinase signaling pathway confers susceptibility to hyperoxic lung injury in mice. Am J Physiol Lung Cell Mol Physiol 2003;285:L250-L257.
29. Morse D, Pischke SE, Zhou Z, Davis RJ, Flavell RA, Loop Torsten, Otterbein SL, Otterbein LE, Choi AMK. Suppression of inflammatory cytokine production by carbon monoxide involves the c-Jun NH2-terminal kinase (JNK) pathway and activator protein-1 (AP-1). J Biol Chem 2003;278:36993-36998.
30. Tournier C, Hess P, Yang DD, Xu J, Turner TK, Nimnual A, Bar-Sagi D, Jones SN, Flavell RA, Davis RJ. Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science 2000;288:870-874.
31. Hochedlinger K, Wagner EF, Sabapathy K. Differential effects of JNK1 and JNK2 on signal specific induction of apoptosis. Oncogene 2002;21:2441-2445.
32. Park WY, Goodman RB, Steiberg KP, Ruzinski JT, Radella F, Park DR, Pugin J, Skerrett SJ, Hudson LD, Martin TR. Cytokine balance in the lungs of patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 2001;164:1896-1903.
33. Ribeiro SP, Rhee K, Tremblay L, Veldhuizen R, Lewis JF, Slutsky AS. Heat stress attenuates ventilator-induced lung dysfunction in an ex vivo rat lung model. Am J Respir Crit Care Med 2001;163:1451-1456.
34. Ricard JD, Dreyfuss D, Saumon G. Production of inflammatory cytokines in ventilator-induced lung injury: a reappraisal. Am J Respir Crit Care Med 2001;163:1176-1180.
35. Kunkel SL, Standiford T, Kasahara K, Stricter RM. Interleukin-8 (IL-8): the major neutrophil chemotactic factor in the lung. Exp Lung Res 1991;17:17-23.
36. Kurdowska A, Noble JM, Steinber KP, Ruzinski JT, Hudson LD, Martin TR. Anti-interleukin 8 autoantibody: interleukin 8 complexes in the acute respiratory distress syndrome: relationship between the complexes and clinical disease activity. Am J Respir Crit Care Med 2001;163:463-468.
37. Schmal H, Shanley TP, Jones ML, Friedl HP, Ward PA. Role for macrophage inflammatory protein-2 in lipopolysaccharide-induced lung injury in rats. J Immunol 1996;156:1963-1972.
38. Cerretti DP, Kozlosky CJ, Bos TV, Nelsen N, Gearing DP, Beckmann MP. Molecular characterization of receptors for human interleukin 8, GRO/melanoma growth-stimulatory activity, and neutrophil activating peptide-2. Mol Immunol 1993;30:359-367.
39. Jaramillo M, Olivier M. Hydrogen peroxide induces murine macrophage chemokine gene transcription via extracellular signal-regulated kinase and cyclic adenosine 5′-monophosphate (cAMP)-dependent pathways: involvement of NK-kappa B, activator protein 1, and cAMP responsive element binding. J Immunol 2002;169:7026-7038.
40. Cronstein BN, Kimmel SC, Levin RI, Martiniuk F, Weissmann G. A mechanism for the antiinflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1. Proc Natl Acad Sci USA 1992;89:9991-9995.
41. Imanaka H, Shimaoka M, Matsuura N, Nishimura M, Ohta N, Kiyono H. Ventilator-induced lung injury is associated with neutrophil infiltration, macrophage activation, and TGF-β1 mRNA upregulation in rat lungs. Anesth Analg 2001;92:428-436.
42. Eichacker PQ, Gerstenberger EP, Banks SM, Cui X, Natanson C. Metaanalysis of acute lung injury and acute respiratory distress syndrome trials testing low tidal volumes. Am J Respir Crit Care Med 2002;166:1510-1514.
43. Frank JA, Gutierrez JA, Jones KD, Allen L, Dobbs L, Matthay MA. Low tidal volume reduces epithelial and endothelial injury in acid-injured rat lungs. Am J Respir Crit Care Med 2002;165:242-249.
44. Matthay MA, Zimmeran GA, Esmon C, Bhattacharya J, Coller B, Doerschuk CM, Floros J, Bimbrone MA Jr, Hoffman E, Hubmayr RD, et al. Future research directions in acute lung injury: summary of a National Heart, Lung, and Blood Institute working group. Am J Respir Crit Care Med 2003;167:1027-1035.