Kinetic and reversibility of mechanical ventilation-associated pulmonary and systemic inflammatory response in patients with acute lung injury

Intensive Care Medicine

Volumn 28, Issue 7, 2002, Pages 834-841

  Stuber F ^a   Wrigge, H ^a   Schroeder, S ^a   Wetegrove, S ^a   Zinserling, J ^a   Hoeft, A ^a   Putensen, C ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

Acute lung injury; Acute respiratory distress syndrome; Inflammatory cytokines; Positive pressure ventilation; Protective mechanical ventilation

Indexed keywords

INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 6; TUMOR NECROSIS FACTOR; AUTACOID;

ADULT; ARTICLE; ARTIFICIAL VENTILATION; BLOOD LEVEL; BODY WEIGHT; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; INTENSIVE CARE; KINETICS; LUNG INJURY; LUNG LAVAGE; MALE; OXYGEN TENSION; PNEUMONIA; POSITIVE END EXPIRATORY PRESSURE; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; UNIVERSITY HOSPITAL; ADULT RESPIRATORY DISTRESS SYNDROME; BLOOD; CROSSOVER PROCEDURE; GERMANY; INTENSIVE CARE UNIT; METABOLISM; PATHOPHYSIOLOGY; PROSPECTIVE STUDY; VENTILATOR;

BRONCHOALVEOLAR LAVAGE FLUID; CROSS-OVER STUDIES; GERMANY; HUMAN; INFLAMMATION MEDIATORS; INTENSIVE CARE UNITS; PNEUMONIA; POSITIVE-PRESSURE RESPIRATION; PROSPECTIVE STUDIES; RESPIRATORY DISTRESS SYNDROME, ADULT; SEPSIS SYNDROME; SUPPORT, NON-U.S. GOV'T; VENTILATORS, MECHANICAL; HUMANS; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

EID: 0036020303     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00134-002-1321-7     Document Type: Article

References (43)

1. Host defense response and outcome in ARDS
2. Relationships between lung computed tomographic density, gas exchange, and PEEP in acute respiratory failure
3. Ventilation-perfusion distributions in the adult respiratory distress syndrome
4. The relation of pneumothorax and other air leaks to mortality in the acute respiratory distress syndrome
5. Lung structure and function in different stages of severe adult respiratory distress syndrome
6. Beneficial effects of the "open lung approach" with low distending pressures in acute respiratory distress syndrome. A prospective randomized study on mechanical ventilation
7. Selecting ventilator settings according to variables derived from the quasi-static pressure/volume relationship in patients with acute lung injury
8. Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome
9. Low mortality associated with low volume pressure limited ventilation with permissive hypercapnia in severe adult respiratory distress syndrome
10. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome
11. Activation of human macrophages by mechanical ventilation in vitro
12. Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model
13. Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: A randomized controlled trial
14. Report of the American-European consensus conference on ARDS: Definitions mechanisms relevant outcomes and clinical trial coordination
15. Prognosis in acute organ-system failure
16. A simplified acute physiology score for ICU patients
17. Pressure-volume curve of total respiratory system in acute respiratory failure. Computed tomographic scan study
18. Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome
19. Tidal volume reduction for prevention of ventilator-induced lung injury in acute respiratory distress syndrome. The Multicenter Trail Group on Tidal Volume reduction in ARDS
20. Evaluation of a ventilation strategy to prevent barotrauma in patients at high risk for acute respiratory distress syndrome
21. Role of tidal volume FRC and end-inspiratory volume in the development of pulmonary edema following mechanical ventilation
22. Tidal ventilation at low airway pressures can augment lung injury
23. Stress distribution in lungs: A model of pulmonary elasticity
24. Causes of mortality in patients with adult respiratory distress syndrome
25. Improved survival of patients with acute respiratory distress syndrome (ARDS): 1983-1993
26. Interactions between respiratory epithelial cells and cytokines: Relationships to lung inflammation
27. Mechanical ventilation as a mediator of multisystem organ failure in acute respiratory distress syndrome
28. Effect of cyclic stretch on endothelial cells from different vascular beds
29. Stretch induces cytokine release by alveolar epithelial cells in vitro
30. High bronchoalveolar levels of tumor necrosis factor and its inhibitors interleukin-1 interferon and elastase in patients with adult respiratory distress syndrome after trauma shock or sepsis
31. Persistent elevation of inflammatory cytokines predicts a poor outcome in ARDS. Plasma IL-1 beta and IL-6 levels are consistent and efficient predictors of outcome over time
32. Inflammatory cytokines in the BAL of patients with ARDS. Persistent elevation over time predicts poor outcome
33. Inflammatory cytokines in patients with persistence of the acute respiratory distress syndrome
34. Cytokines derived from alveolar macrophages induce fever after bronchoscopy and bronchoalveolar lavage
35. Cardiopulmonary effects of bronchoalveolar lavage in critically ill patients
36. Safety of bronchoalveolar lavage in patients with adult respiratory distress syndrome
37. Cytokine balance in the lungs of patients with acute respiratory distress syndrome
38. Hyperventilation induces release of cytokines from perfused mouse lung
39. Production of inflammatory cytokines in ventilator-induced lung injury: A reappraisal
40. Effects of mechanical ventilation on release of cytokines into systemic circulation in patients with normal pulmonary function
41. Effect of mechanical ventilation strategy on dissemination of intratracheally instilled Escherichia coli in dogs
42. Ventilator-induced lung injury leads to loss of alveolar and systemic compartmentalization of tumor necrosis factor-alpha
43. Alterations of ambient oxygen tension modulate the expression of tumor necrosis factor and macrophage inflammatory protein-1 alpha from murine alveolar macrophages