Mechanical ventilation strategies and inflammatory responses to cardiac surgery: A prospective randomized clinical trial

Intensive Care Medicine

Volumn 31, Issue 10, 2005, Pages 1379-1387

  Wrigge, Hermann ^a   Uhlig, Ulrike ^b   Baumgarten, Georg ^a   Menzenbach, Jan ^a   Zinserling, Jörg ^a   Ernst, Martin ^b   Drömann, Daniel ^b   Welz, Armin ^a   Uhlig, Stefan ^b   Putensen, Christian ^a  

^a UNIVERSITY OF BONN   (Germany)

^b RESEARCH CENTER BORSTEL   (Germany)

Author keywords

Cardiac surgery; Cytokines; Mechanical ventilation; Ventilator induced lung injury

Indexed keywords

INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; ARTIFICIAL VENTILATION; BODY WEIGHT; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HEART SURGERY; HUMAN; INTENSIVE CARE; INTENSIVE CARE UNIT; LUNG GAS EXCHANGE; LUNG LAVAGE; MALE; POSTOPERATIVE INFLAMMATION; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL; SMOKING; TIDAL VOLUME;

AGED; CORONARY ARTERY BYPASS; CYTOKINES; FEMALE; HUMANS; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; PNEUMONIA; POSTOPERATIVE CARE; PROSPECTIVE STUDIES; PULMONARY GAS EXCHANGE; RESPIRATION, ARTIFICIAL; SMOKING;

EID: 26444498681     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00134-005-2767-1     Document Type: Article

References (38)

1. Ranieri VM, Suter PM, Tortorella C, De Tullio R, Dayer JM, Brienza A, Bruno F, Slutsky AS (1999) Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: a randomized controlled trial. JAMA 282:54-61
2. Silverman HJ, Luce JM, Lanken PN, Morris AH, Harabin AL, Oldmixon CF, Thompson BT, Bernard GR (2005) Recommendations for informed consent forms for critical care clinical trials. Crit Care Med 33:867-882
3. Parsons PE, Eisner MD, Thompson BT, Matthay MA, Ancukiewicz M, Bernard GR, Wheeler AP (2005) Lower tidal volume ventilation and plasma cytokine markers of inflammation in patients with acute lung injury. Crit Care Med 33:1-6
4. Acute Respiratory Distress Syndrome Network (2000) Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 342:1301-1308
5. Amato MB, Barbas CS, Medeiros DM, Magaldi RB, Schettino GP, Lorenzi FG, Kairalla RA, Deheinzelin D, Munoz C, Oliveira R, Takagaki TY, Carvalho CR (1998) Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med 338:347-354
6. Cremer J, Martin M, Redl H, Bahrami S, Abraham C, Graeter T, Haverich A, Schlag G, Borst HG (1996) Systemic inflammatory response syndrome after cardiac operations. Ann Thorac Surg 61:1714-1720
7. Kilger E, Weis F, Briegel J, Frey L, Goetz AE, Reuter D, Nagy A, Schuetz A, Lamm P, Knoll A, Peter K (2003) Stress doses of hydrocortisone reduce severe systemic inflammatory response syndrome and improve early outcome in a risk group of patients after cardiac surgery. Crit Care Med 31:1068-1074
8. Wrigge H, Uhlig U, Zinserling J, Behrends-Callsen E, Ottersbach G, Fischer M, Uhlig S, Putensen C (2004) The effects of different ventilatory settings on pulmonary and systemic inflammatory responses during major surgery. Anesth Analg 98:775-81, table
9. Wrigge H, Zinserling J, Stüber F, Spiegel T, Hering R, Wetegrove S, Hoeft A, Putensen C (2000) Effects of mechanical ventilation on release of cytokines into systemic circulation in patients with normal pulmonary function. Anesthesiology 93:1413-1417
10. Stewart TE, Meade MO, Cook DJ, Granton JT, Hodder RV, Lapinsky SE, Mazer CD, McLean RF, Rogovein TS, Schouten BD, Todd TR, Slutsky AS (1998) Evaluation of a ventilation strategy to prevent barotrauma in patients at high risk for acute respiratory distress syndrome. Pressure- and Volume-Limited Ventilation Strategy Group. N Engl J Med 338:355-361
11. Viitanen A, Salmenpera M, Heinonen J (1990) Right ventricular response to hypercarbia after cardiac surgery. Anesthesiology 73:393-400
12. Wrigge H, Uhlig U, Menzenbach J, Zinserling J, Uhlig S, Putensen, C (2003) Does postperative ventilatory strategy affect inflammatory response to cardiac surgery in smokers and non-smokers (abstract)? Am J Respir Crit Care Med 167[Suppl]:A905
13. Wrigge H, Uhlig U, Menzenbach J, Zinserling J, Uhlig S, Putensen, C (2003) Inflammatory effects of conventional and lower tidal volume ventilation after cardiac surgery (abstract). Intensive Care Med 29 [Suppl 1]:S307
14. Hachenberg T, Tenling A, Nystrom SO, Tyden H, Hedenstierna G (1994) Ventilation-perfusion inequality in patients undergoing cardiac surgery. Anesthesiology 80:509-519
15. Hachenberg T, Tenling A, Hansson HE, Tyden H, Hedenstierna G (1997) The ventilation-perfusion relation and gas exchange in mitral valve disease and coronary artery disease. Implications for anesthesia, extracorporeal circulation, and cardiac surgery. Anesthesiology 86:809-817
16. Boldt J, Osmer C, Linke LC, Dapper F, Hempelmann G (1995) Circulating adhesion molecules in pediatric cardiac surgery. Anesth Analg 81:1129-1135
17. Nathan N, Denizot Y, Cornu E, Jauberteau MO, Chauvreau C, Feiss P (1997) Cytokine and lipid mediator blood concentrations after coronary artery surgery. Anesth Analg 85:1240-1246
18. Berendes E, Mollhoff T, Van Aken H, Schmidt C, Erren M, Deng MC, Weyand M, Loick HM (1997) Effects of dopexamine on creatinine clearance, systemic inflammation, and splanchnic oxygenation in patients undergoing coronary artery bypass grafting. Anesth Analg 84:950-957
19. Gilliland HE, Armstrong MA, McMurray TJ (1999) The inflammatory response to pediatric cardiac surgery: correlation of granulocyte adhesion molecule expression with postoperative oxygenation. Anesth Analg 89:1188-1191
20. Milot J, Perron J, Lacasse Y, Letourneau L, Cartier PC, Maltais F (2001) Incidence and predictors of ARDS after cardiac surgery. Chest 119:884-888
21. Koner O, Celebi S, Balci H, Cetin G, Karaoglu K, Cakar N (2004) Effects of protective and conventional mechanical ventilation on pulmonary function and systemic cytokine release after cardiopulmonary bypass. Intensive Care Med 30:620-626
22. International Consensus Conferences in Intensive Care Medicine (1999) Ventilator-associated lung injury in ARDS. American Thoracic Society, European Society of Intensive Care Medicine, Societe de Reanimation Langue Francaise. Intensive Care Med 25:1444-1452
23. Miller FG, Silverman HJ (2004) The ethical relevance of the standard of care in the design of clinical trials. Am J Respir Crit Care Med 169:562-564
24. Brower RG, Bernard G, Morris A (2004) Ethics and standard of care in clinical trials. Am J Respir Crit Care Med 170:198-199
25. Montravers P, Gauzit R, Dombret MC, Blanchet F, Desmonts JM (1993) Cardiopulmonary effects of bronchoalveolar lavage in critically ill patients. Chest 104:1541-1547
26. Steinberg KP, Mitchell DR, Maunder RJ, Milberg JA, Whitcomb ME, Hudson LD (1993) Safety of bronchoalveolar lavage in patients with adult respiratory distress syndrome. Am Rev Respir Dis 148:556-561
27. Krause A, Hohberg B, Heine F, John M, Burmester GR, Witt C (1997) Cytokines derived from alveolar macrophages induce fever after bronchoscopy and bronchoalveolar lavage. Am J Respir Crit Care Med 155:1793-1797
28. Pugin J (2002) Is the ventilator responsible for lung and systemic inflammation? Intensive Care Med 28:817-819
29. Abraham E, Wunderink R, Silverman H, Perl TM, Nasraway S, Levy H, Bone R, Wenzel RP, Balk R, Allred R (1995) Efficacy and safety of monoclonal antibody to human tumor necrosis factor alpha in patients with sepsis syndrome. A randomized, controlled, double-blind, multicenter clinical trial. TNF-alpha MAb Sepsis Study Group. JAMA 273:934-941
30. Schroeder S, Borger N, Wrigge H, Welz A, Putensen C, Hoeft A, Stüber F (2003) A tumor necrosis factor gene polymorphism influences the inflammatory response after cardiac operation. Ann Thorac Surg 75:534-537
31. Tomasdottir H, Hjartarson H, Ricksten A, Wasslavik C, Bengtsson A, Ricksten SE (2003) Tumor necrosis factor gene polymorphism is associated with enhanced systemic inflammatory response and increased cardiopulmonary morbidity after cardiac surgery. Anesth Analg 97:944-949
32. Hickling KG, Henderson SJ (1990) Low mortality associated with low volume pressure limited ventilation with permissive hypercapnia in severe adult respiratory distress syndrome. Intensive Care Med 16:372-377
33. Stüber F, Wrigge H, Schroeder S, Wetegrove S, Zinserling J, Hoeft A, Putensen C (2002) Kinetic and reversibility of mechanical ventilation- associated pulmonary and systemic inflammatory response in patients with acute lung injury. Intensive Care Med 28:834-841
34. Johnson MR (1999) Low systemic vascular resistance after cardiopulmonary bypass: are we any closer to understanding the enigma? Crit Care Med 27:1048-1050
35. Tremblay L, Valenza F, Ribeiro SP, Li J, Slutsky AS (1997) Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model. J Clin Invest 99:944-952
36. Chiumello D, Pristine G, Slutsky AS (1999) Mechanical ventilation affects local and systemic cytokines in an animal model of acute respiratory distress syndrome. Am J Respir Crit Care Med 160:109-116
37. Held HD, Boettcher S, Hamann L, Uhlig S (2001) Ventilation-induced chemokine and cytokine release is associated with activation of nuclear factor-kappaB and is blocked by steroids. Am J Respir Crit Care Med 163:711-716
38. Laffey JG, O'Croinin D, McLoughlin P, Kavanagh BP (2004) Permissive hypercapnia - role in protective lung ventilatory strategies. Intensive Care Med 30:347-356