-
1
-
-
0036550559
-
Effector and memory Tcell differentiation: Implications for vaccine development
-
Kaech, S. M., Wherry, E. J., Ahmed, R. (2002) Effector and memory Tcell differentiation: implications for vaccine development. Nat. Rev. Immunol. 2, 251-262.
-
(2002)
Nat. Rev. Immunol
, vol.2
, pp. 251-262
-
-
Kaech, S.M.1
Wherry, E.J.2
Ahmed, R.3
-
2
-
-
0037432787
-
Requirement for CD4 T cell help in generating functional CD8 T cell memory
-
Shedlock, D. J., Shen, H. (2003) Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 300, 337-339.
-
(2003)
Science
, vol.300
, pp. 337-339
-
-
Shedlock, D.J.1
Shen, H.2
-
3
-
-
0037432776
-
Defective CD8 T cell memory following acute infection without CD4 T cell help
-
Sun, J. C., Bevan, M. J. (2003) Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 300, 339-342.
-
(2003)
Science
, vol.300
, pp. 339-342
-
-
Sun, J.C.1
Bevan, M.J.2
-
4
-
-
0037456367
-
CD4_ T cells are required for secondary expansion and memory in CD8+ T lymphocytes
-
Janssen, E. M., Lemmens, E. E., Wolfe, T., Christen, U., von Herrath, M. G., Schoenberger, S. P. (2003) CD4_ T cells are required for secondary expansion and memory in CD8_ T lymphocytes. Nature 421, 852-856.
-
(2003)
Nature
, vol.421
, pp. 852-856
-
-
Janssen, E.M.1
Lemmens, E.E.2
Wolfe, T.3
Christen, U.4
von Herrath, M.G.5
Schoenberger, S.P.6
-
5
-
-
33646686040
-
HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells
-
Betts, M. R., Nason, M. C., West, S. M., De Rosa, S. C., Migueles, S. A., Abraham, J., Lederman, M. M., Benito, J. M., Goepfert, P. A., Connors, M., Roederer, M., Koup, R. A. (2006) HIV nonprogressors preferentially maintain highly functional HIV-specific CD8_ T cells. Blood 107, 4781-4789.
-
(2006)
Blood
, vol.107
, pp. 4781-4789
-
-
Betts, M.R.1
Nason, M.C.2
West, S.M.3
de Rosa, S.C.4
Migueles, S.A.5
Abraham, J.6
Lederman, M.M.7
Benito, J.M.8
Goepfert, P.A.9
Connors, M.10
Roederer, M.11
Koup, R.A.12
-
6
-
-
0034123842
-
The role of CD4(+) T helper cells in the cytotoxic T lymphocyte response to HIV-1
-
Altfeld, M., Rosenberg, E. S. (2000) The role of CD4(+) T helper cells in the cytotoxic T lymphocyte response to HIV-1. Curr. Opin. Immunol. 12, 375-380.
-
(2000)
Curr. Opin. Immunol
, vol.12
, pp. 375-380
-
-
Altfeld, M.1
Rosenberg, E.S.2
-
7
-
-
0030665257
-
+ T cell responses associated with control of viremia
-
+ T cell responses associated with control of viremia. Science 278, 1447-1450.
-
(1997)
Science
, vol.278
, pp. 1447-1450
-
-
Rosenberg, E.S.1
Billingsley, J.M.2
Caliendo, A.M.3
Boswell, S.L.4
Sax, P.E.5
Kalams, S.A.6
Walker, B.D.7
-
8
-
-
67649876115
-
New insights into the regulation of T cells by γ (c) family cytokines
-
Rochman, Y., Spolski, R., Leonard, W. J. (2009) New insights into the regulation of T cells by _(c) family cytokines. Nat. Rev. Immunol. 9, 480-490.
-
(2009)
Nat. Rev. Immunol
, vol.9
, pp. 480-490
-
-
Rochman, Y.1
Spolski, R.2
Leonard, W.J.3
-
9
-
-
33746547247
-
The biology of interleukin-2 and interleukin-15: Implications for cancer therapy and vaccine design
-
Waldmann, T. A. (2006) The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design. Nat. Rev. Immunol. 6, 595-601.
-
(2006)
Nat. Rev. Immunol
, vol.6
, pp. 595-601
-
-
Waldmann, T.A.1
-
10
-
-
42449106871
-
IL-15 as a mediator of CD4+ help for CD8+ T cell longevity and avoidance of TRAIL-mediated apoptosis
-
Oh, S., Perera, L. P., Terabe, M., Ni, L., Waldmann, T. A., Berzofsky, J. A. (2008) IL-15 as a mediator of CD4_ help for CD8_ T cell longevity and avoidance of TRAIL-mediated apoptosis. Proc. Natl. Acad. Sci. USA 105, 5201-5206.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 5201-5206
-
-
Oh, S.1
Perera, L.P.2
Terabe, M.3
Ni, L.4
Waldmann, T.A.5
Berzofsky, J.A.6
-
11
-
-
21244447927
-
Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help
-
Kutzler, M. A., Robinson, T. M., Chattergoon, M. A., Choo, D. K., Choo, A. Y., Choe, P. Y., Ramanathan, M. P., Parkinson, R., Kudchodkar, S., Tamura, Y., Sidhu, M., Roopchand, V., Kim, J. J., Pavlakis, G. N., Felber, B. K., Waldmann, T. A., Boyer, J. D., Weiner, D. B. (2005) Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help. J. Immunol. 175, 112-123.
-
(2005)
J. Immunol
, vol.175
, pp. 112-123
-
-
Kutzler, M.A.1
Robinson, T.M.2
Chattergoon, M.A.3
Choo, D.K.4
Choo, A.Y.5
Choe, P.Y.6
Ramanathan, M.P.7
Parkinson, R.8
Kudchodkar, S.9
Tamura, Y.10
Sidhu, M.11
Roopchand, V.12
Kim, J.J.13
Pavlakis, G.N.14
Felber, B.K.15
Waldmann, T.A.16
Boyer, J.D.17
Weiner, D.B.18
-
12
-
-
0028356759
-
An epitope in hepatitis C virus core region recognized by cytotoxic T cells in mice and humans
-
Shirai, M., Okada, H., Nishioka, M., Akatsuka, T., Wychowski, C., Houghten, R., Pendleton, C. D., Feinstone, S. M., Berzofsky, J. A. (1994) An epitope in hepatitis C virus core region recognized by cytotoxic T cells in mice and humans. J. Virol. 68, 3334-3342.
-
(1994)
J. Virol
, vol.68
, pp. 3334-3342
-
-
Shirai, M.1
Okada, H.2
Nishioka, M.3
Akatsuka, T.4
Wychowski, C.5
Houghten, R.6
Pendleton, C.D.7
Feinstone, S.M.8
Berzofsky, J.A.9
-
13
-
-
0023256436
-
Cytotoxic T lymphocytes recognize a fragment of influenza virus matrix protein in association with HLA-A2
-
Gotch, F., Rothbard, J., Howland, K., Townsend, A. R. M., McMichael, A. J. (1987) Cytotoxic T lymphocytes recognize a fragment of influenza virus matrix protein in association with HLA-A2. Nature 326, 881-882.
-
(1987)
Nature
, vol.326
, pp. 881-882
-
-
Gotch, F.1
Rothbard, J.2
Howland, K.3
Townsend, A.R.M.4
McMichael, A.J.5
-
14
-
-
60149094003
-
Effect of ex vivo culture duration on phenotype and cytokine production by mature dendritic cells derived from peripheral blood monocytes
-
Tawab, A., Fan, Y., Read, E. J., Kurlander, R. J. (2009) Effect of ex vivo culture duration on phenotype and cytokine production by mature dendritic cells derived from peripheral blood monocytes. Transfusion 49, 536-547.
-
(2009)
Transfusion
, vol.49
, pp. 536-547
-
-
Tawab, A.1
Fan, Y.2
Read, E.J.3
Kurlander, R.J.4
-
15
-
-
20844440192
-
Survival adjustment of mature dendritic cells by IL-15
-
Dubois, S. P., Waldmann, T. A., Muller, J. R. (2005) Survival adjustment of mature dendritic cells by IL-15. Proc. Natl. Acad. Sci. USA 102, 8662-8667.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 8662-8667
-
-
Dubois, S.P.1
Waldmann, T.A.2
Muller, J.R.3
-
16
-
-
57449090632
-
Dendritic cell-based human immunodeficiency virus vaccine
-
Rinaldo, C. R. (2009) Dendritic cell-based human immunodeficiency virus vaccine. J. Intern. Med. 265, 138-158.
-
(2009)
J. Intern. Med
, vol.265
, pp. 138-158
-
-
Rinaldo, C.R.1
-
17
-
-
35948999237
-
Enhanced activation of human dendritic cells by inducible CD40 and Toll-like receptor-4 ligation
-
Lapteva, N., Seethammagari, M. R., Hanks, B. A., Jiang, J., Levitt, J. M., Slawin, K. M., Spencer, D. M. (2007) Enhanced activation of human dendritic cells by inducible CD40 and Toll-like receptor-4 ligation. Cancer Res. 67, 10528-10537.
-
(2007)
Cancer Res
, vol.67
, pp. 10528-10537
-
-
Lapteva, N.1
Seethammagari, M.R.2
Hanks, B.A.3
Jiang, J.4
Levitt, J.M.5
Slawin, K.M.6
Spencer, D.M.7
-
18
-
-
0034553631
-
The role of CD4(+) T cell help and CD40 ligand in the in vitro expansion of HIV-1-specific memory cytotoxic CD8(+) T cell responses
-
Ostrowski, M. A., Justement, S. J., Ehler, L., Mizell, S. B., Lui, S., Mican, J., Walker, B. D., Thomas, E. K., Seder, R., Fauci, A. S. (2000) The role of CD4(_) T cell help and CD40 ligand in the in vitro expansion of HIV-1-specific memory cytotoxic CD8(_) T cell responses. J. Immunol. 165, 6133-6141.
-
(2000)
J. Immunol
, vol.165
, pp. 6133-6141
-
-
Ostrowski, M.A.1
Justement, S.J.2
Ehler, L.3
Mizell, S.B.4
Lui, S.5
Mican, J.6
Walker, B.D.7
Thomas, E.K.8
Seder, R.9
Fauci, A.S.10
-
19
-
-
55949118498
-
Flow cytometric detection of perforin upregulation in human CD8 T cells
-
Hersperger, A. R., Makedonas, G., Betts, M. R. (2008) Flow cytometric detection of perforin upregulation in human CD8 T cells. Cytometry A 73, 1050-1057.
-
(2008)
Cytometry A
, vol.73
, pp. 1050-1057
-
-
Hersperger, A.R.1
Makedonas, G.2
Betts, M.R.3
-
20
-
-
0037342345
-
Studies on the production of IL-15 in HIV-infected/AIDS patients
-
Ahmad, R., Sindhu, S. T., Toma, E., Morisset, R., Ahmad, A. (2003) Studies on the production of IL-15 in HIV-infected/AIDS patients. J. Clin. Immunol. 23, 81-90.
-
(2003)
J. Clin. Immunol
, vol.23
, pp. 81-90
-
-
Ahmad, R.1
Sindhu, S.T.2
Toma, E.3
Morisset, R.4
Ahmad, A.5
-
21
-
-
0032418812
-
The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses
-
Kalams, S. A., Walker, B. D. (1998) The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses. J. Exp. Med. 188, 2199-2204.
-
(1998)
J. Exp. Med
, vol.188
, pp. 2199-2204
-
-
Kalams, S.A.1
Walker, B.D.2
-
22
-
-
3543099130
-
Helping the CD8(+) T-cell response
-
Bevan, M. J. (2004) Helping the CD8(_) T-cell response. Nat. Rev. Immunol. 4, 595-602.
-
(2004)
Nat. Rev. Immunol
, vol.4
, pp. 595-602
-
-
Bevan, M.J.1
-
23
-
-
0032482337
-
A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell
-
Ridge, J. P., Di Rosa, F., Matzinger, P. (1998) A conditioned dendritic cell can be a temporal bridge between a CD4_ T-helper and a T-killer cell. Nature 393, 474-478.
-
(1998)
Nature
, vol.393
, pp. 474-478
-
-
Ridge, J.P.1
di Rosa, F.2
Matzinger, P.3
-
24
-
-
0032482356
-
Help for cytotoxic-T-cell responses is mediated by CD40 signaling
-
Bennett, S. R. M., Carbone, F. R., Karamalis, F., Flavell, R. A., Miller, J. F. A. P., Heath, W. R. (1998) Help for cytotoxic-T-cell responses is mediated by CD40 signaling. Nature 393, 478-480.
-
(1998)
Nature
, vol.393
, pp. 478-480
-
-
Bennett, S.R.M.1
Carbone, F.R.2
Karamalis, F.3
Flavell, R.A.4
Miller, J.F.A.P.5
Heath, W.R.6
-
25
-
-
0032482474
-
T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions
-
Schoenberger, S. P., Toes, R. E. M., van der Voort, E. I. H., Offringa, R., Melief, C. J. M. (1998) T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature 393, 480-483.
-
(1998)
Nature
, vol.393
, pp. 480-483
-
-
Schoenberger, S.P.1
Toes, R.E.M.2
van der Voort, E.I.H.3
Offringa, R.4
Melief, C.J.M.5
-
26
-
-
0024786954
-
Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virusseropositive patients: Independence of CD4 cell numbers and clinical staging
-
Clerici, M., Stocks, N. I., Zajac, R. A., Boswell, R. N., Lucey, D. R., Via, C. S., Shearer, G. M. (1989) Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virusseropositive patients: independence of CD4 cell numbers and clinical staging. J. Clin. Invest. 84, 1892-1899.
-
(1989)
J. Clin. Invest
, vol.84
, pp. 1892-1899
-
-
Clerici, M.1
Stocks, N.I.2
Zajac, R.A.3
Boswell, R.N.4
Lucey, D.R.5
Via, C.S.6
Shearer, G.M.7
-
27
-
-
0032433127
-
The central role of CD4(+) T cells in the antitumor immune response
-
Hung, K., Hayashi, R., Lafond-Walker, A., Lowenstein, C., Pardoll, D., Levitsky, H. (1998) The central role of CD4(_) T cells in the antitumor immune response. J. Exp. Med. 188, 2357-2368.
-
(1998)
J. Exp. Med
, vol.188
, pp. 2357-2368
-
-
Hung, K.1
Hayashi, R.2
Lafond-Walker, A.3
Lowenstein, C.4
Pardoll, D.5
Levitsky, H.6
-
28
-
-
77953118149
-
Innate and adaptive immune correlates of vaccine and adjuvant-induced control of mucosal transmission of SIV in macaques
-
Sui, Y., Zhu, Q., Gagnon, S., Dzutsev, A., Terabe, M., Vaccari, M., Venzon, D., Klinman, D., Strober, W., Kelsall, B., Franchini, G., Belyakov, I. M., Berzofsky, J. A. (2010) Innate and adaptive immune correlates of vaccine and adjuvant-induced control of mucosal transmission of SIV in macaques. Proc. Natl. Acad. Sci. USA 107, 9843-9848.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 9843-9848
-
-
Sui, Y.1
Zhu, Q.2
Gagnon, S.3
Dzutsev, A.4
Terabe, M.5
Vaccari, M.6
Venzon, D.7
Klinman, D.8
Strober, W.9
Kelsall, B.10
Franchini, G.11
Belyakov, I.M.12
Berzofsky, J.A.13
-
29
-
-
57149086082
-
In vivo expansion, persistence, and function of peptide vaccine-induced CD8 T cells occur independently of CD4 T cells
-
Assudani, D., Cho, H. I., DeVito, N., Bradley, N., Celis, E. (2008) In vivo expansion, persistence, and function of peptide vaccine-induced CD8 T cells occur independently of CD4 T cells. Cancer Res. 68, 9892-9899.
-
(2008)
Cancer Res
, vol.68
, pp. 9892-9899
-
-
Assudani, D.1
Cho, H.I.2
Devito, N.3
Bradley, N.4
Celis, E.5
-
30
-
-
76249130335
-
Interleukin-15 and its receptor augment dendritic cell vaccination against the neu oncogene through the induction of antibodies partially independent of CD4 help
-
Steel, J. C., Ramlogan, C. A., Yu, P., Sakai, Y., Forni, G., Waldmann, T. A., Morris, J. C. (2010) Interleukin-15 and its receptor augment dendritic cell vaccination against the neu oncogene through the induction of antibodies partially independent of CD4 help. Cancer Res. 70, 1072-1081.
-
(2010)
Cancer Res
, vol.70
, pp. 1072-1081
-
-
Steel, J.C.1
Ramlogan, C.A.2
Yu, P.3
Sakai, Y.4
Forni, G.5
Waldmann, T.A.6
Morris, J.C.7
-
31
-
-
0035102242
-
Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: Implications for immunotherapy
-
Waldmann, T. A., Dubois, S., Tagaya, Y. (2001) Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for immunotherapy. Immunity 14, 105-110.
-
(2001)
Immunity
, vol.14
, pp. 105-110
-
-
Waldmann, T.A.1
Dubois, S.2
Tagaya, Y.3
-
32
-
-
0033046593
-
The multifaceted regulation of interleukin- 15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens
-
Waldmann, T. A., Tagaya, Y. (1999) The multifaceted regulation of interleukin- 15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens. Annu. Rev. Immunol. 17, 19-49.
-
(1999)
Annu. Rev. Immunol
, vol.17
, pp. 19-49
-
-
Waldmann, T.A.1
Tagaya, Y.2
-
33
-
-
0036005891
-
Interleukin-2 and interleukin-15: Immunotherapy for cancer
-
Fehniger, T. A., Cooper, M. A., Caligiuri, M. A. (2002) Interleukin-2 and interleukin-15: immunotherapy for cancer. Cytokine Growth Factor Rev. 13, 169-183.
-
(2002)
Cytokine Growth Factor Rev
, vol.13
, pp. 169-183
-
-
Fehniger, T.A.1
Cooper, M.A.2
Caligiuri, M.A.3
-
34
-
-
0035169507
-
Interleukin 15: Biology and relevance to human disease
-
Fehniger, T. A., Caligiuri, M. A. (2001) Interleukin 15: biology and relevance to human disease. Blood 97, 14-32.
-
(2001)
Blood
, vol.97
, pp. 14-32
-
-
Fehniger, T.A.1
Caligiuri, M.A.2
-
35
-
-
78651260395
-
Interleukin-21 and cellular activation concurrently induce potent cytotoxic function and promote antivrial activity in human CD8 T cells
-
Parmigiani, A., Pallin, M., Schmidtmayerova, H., Lichtenheld, M., Pahwa, S. (2011) Interleukin-21 and cellular activation concurrently induce potent cytotoxic function and promote antivrial activity in human CD8 T cells. Hum. Immunol. 72, 115-123.
-
(2011)
Hum. Immunol
, vol.72
, pp. 115-123
-
-
Parmigiani, A.1
Pallin, M.2
Schmidtmayerova, H.3
Lichtenheld, M.4
Pahwa, S.5
-
36
-
-
19944434230
-
Synergy of IL-21 and IL-15 in regulating CD8+ T-cell expansion and function
-
Zeng, R., Spolski, R., Finkelstein, S. E., Oh, S., Kovanen, P. E., Hinrichs, C. S., Pise-Masison, C. A., Radonovich, M. F., Brady, J. N., Restifo, N. P., Berzofsky, J. A., Leonard, W. J. (2005) Synergy of IL-21 and IL-15 in regulating CD8_ T-cell expansion and function. J. Exp. Med. 201, 139 -148.
-
(2005)
J. Exp. Med
, vol.201
, pp. 139-148
-
-
Zeng, R.1
Spolski, R.2
Finkelstein, S.E.3
Oh, S.4
Kovanen, P.E.5
Hinrichs, C.S.6
Pise-Masison, C.A.7
Radonovich, M.F.8
Brady, J.N.9
Restifo, N.P.10
Berzofsky, J.A.11
Leonard, W.J.12
-
37
-
-
0030846020
-
Cytotoxic T-lymphocyte cross-reactivity among different human immunodeficiency virus type 1 clades: Implications for vaccine development
-
Cao, H., Kanki, P., Sankale, J. L., Dieng-Sarr, A., Mazzara, G. P., Kalams, S. A., Korber, B., Mboup, S., Walker, B. D. (1997) Cytotoxic T-lymphocyte cross-reactivity among different human immunodeficiency virus type 1 clades: implications for vaccine development. J. Virol. 71, 8615- 8623.
-
(1997)
J. Virol
, vol.71
, pp. 8623
-
-
Cao, H.1
Kanki, P.2
Sankale, J.L.3
Dieng-Sarr, A.4
Mazzara, G.P.5
Kalams, S.A.6
Korber, B.7
Mboup, S.8
Walker, B.D.9
-
38
-
-
0028122380
-
Shutting down HIV
-
Koup, R. A., Ho, D. D. (1994) Shutting down HIV. Nature 370, 416.
-
(1994)
Nature
, vol.370
, pp. 416
-
-
Koup, R.A.1
Ho, D.D.2
-
39
-
-
0029116868
-
High levels of anti-human immunodeficiency virus type 1 (HIV-1) memory cytotoxic T-lymphocyte activity and low viral load are associated with lack of disease in HIV-1-infected long-term nonprogressors
-
Rinaldo, C., Huang, X. L., Fan, Z. F., Ding, M., Beltz, L., Logar, A., Panicali, D., Mazzara, G., Liebmann, J., Cottrill, M., et al. (1995) High levels of anti-human immunodeficiency virus type 1 (HIV-1) memory cytotoxic T-lymphocyte activity and low viral load are associated with lack of disease in HIV-1-infected long-term nonprogressors. J. Virol. 69, 5838 -5842.
-
(1995)
J. Virol
, vol.69
, pp. 5838-5842
-
-
Rinaldo, C.1
Huang, X.L.2
Fan, Z.F.3
Ding, M.4
Beltz, L.5
Logar, A.6
Panicali, D.7
Mazzara, G.8
Liebmann, J.9
Cottrill, M.10
-
40
-
-
0033524838
-
Control of viremia in simian immunodeficiency virus infection by CD8_ lymphocytes
-
Schmitz, J. E., Kuroda, M. J., Santra, S., Sasseville, V. G., Simon, M. A., Lifton, M. A., Racz, P., Tenner-Racz, K., Dalesandro, M., Scallon, B. J., Ghrayeb, J., Forman, M. A., Montefiori, D. C., Rieber, E. P., Letvin, N. L., Reimann, K. A. (1999) Control of viremia in simian immunodeficiency virus infection by CD8_ lymphocytes. Science 283, 857-860.
-
(1999)
Science
, vol.283
, pp. 857-860
-
-
Schmitz, J.E.1
Kuroda, M.J.2
Santra, S.3
Sasseville, V.G.4
Simon, M.A.5
Lifton, M.A.6
Racz, P.7
Tenner-Racz, K.8
Dalesandro, M.9
Scallon, B.J.10
Ghrayeb, J.11
Forman, M.A.12
Montefiori, D.C.13
Rieber, E.P.14
Letvin, N.L.15
Reimann, K.A.16
-
41
-
-
0033559648
-
Dramatic rise in plasma viremia after CD8+ T cell depletion in simian immunodeficiency virusinfected macaques
-
Jin, X., Bauer, D. E., Tuttleton, S. E., Lewin, S., Gettie, A., Blanchard, J., Irwin, C. E., Safrit, J. T., Mittler, J., Weinberger, L., Kostrikis, L. G., Zhang, L., Perelson, A. S., Ho, D. D. (1999) Dramatic rise in plasma viremia after CD8_ T cell depletion in simian immunodeficiency virusinfected macaques. J. Exp. Med. 189, 991-998.
-
(1999)
J. Exp. Med
, vol.189
, pp. 991-998
-
-
Jin, X.1
Bauer, D.E.2
Tuttleton, S.E.3
Lewin, S.4
Gettie, A.5
Blanchard, J.6
Irwin, C.E.7
Safrit, J.T.8
Mittler, J.9
Weinberger, L.10
Kostrikis, L.G.11
Zhang, L.12
Perelson, A.S.13
Ho, D.D.14
-
42
-
-
0030587823
-
IL-15 stimulates the expansion of AIDS virus-specific CTL1
-
Kanai, T., Thomas, E. K., Yasutomi, Y., Letvin, N. L. (1996) IL-15 stimulates the expansion of AIDS virus-specific CTL1. J. Immunol. 157, 3681- 3687.
-
(1996)
J. Immunol
, vol.157
, pp. 3687
-
-
Kanai, T.1
Thomas, E.K.2
Yasutomi, Y.3
Letvin, N.L.4
-
43
-
-
0037306895
-
IL-15 enhances survival and function of HIV-specific CD8+ T cells
-
Mueller, Y. M., Bojczuk, P. M., Halstead, E. S., Kim, A. H., Witek, J., Altman, J. D., Katsikis, P. D. (2003) IL-15 enhances survival and function of HIV-specific CD8_ T cells. Blood 101, 1024-1029.
-
(2003)
Blood
, vol.101
, pp. 1024-1029
-
-
Mueller, Y.M.1
Bojczuk, P.M.2
Halstead, E.S.3
Kim, A.H.4
Witek, J.5
Altman, J.D.6
Katsikis, P.D.7
-
44
-
-
10744226452
-
IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells
-
Klebanoff, C. A., Finkelstein, S. E., Surman, D. R., Lichtman, M. K., Gattinoni, L., Theoret, M. R., Grewal, N., Spiess, P. J., Antony, P. A., Palmer, D. C., Tagaya, Y., Rosenberg, S. A., Waldmann, T. A., Restifo, N. P. (2004) IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8_ T cells. Proc. Natl. Acad. Sci. USA 101, 1969-1974.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1969-1974
-
-
Klebanoff, C.A.1
Finkelstein, S.E.2
Surman, D.R.3
Lichtman, M.K.4
Gattinoni, L.5
Theoret, M.R.6
Grewal, N.7
Spiess, P.J.8
Antony, P.A.9
Palmer, D.C.10
Tagaya, Y.11
Rosenberg, S.A.12
Waldmann, T.A.13
Restifo, N.P.14
-
45
-
-
14544288632
-
CD4_ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation- induced cell death
-
Janssen, E. M., Droin, N. M., Lemmens, E. E., Pinkoski, M. J., Bensinger, S. J., Ehst, B. D., Griffith, T. S., Green, D. R., Schoenberger, S. P. (2005) CD4_ T-cell help controls CD8_ T-cell memory via TRAIL-mediated activation- induced cell death. Nature 434, 88-93.
-
(2005)
Nature
, vol.434
, pp. 88-93
-
-
Janssen, E.M.1
Droin, N.M.2
Lemmens, E.E.3
Pinkoski, M.J.4
Bensinger, S.J.5
Ehst, B.D.6
Griffith, T.S.7
Green, D.R.8
Schoenberger, S.P.9
-
46
-
-
0032876816
-
Death deflected: IL-15 inhibits TNF-α mediated apoptosis in fibroblasts by TRAF2 recruitment to the IL-15Rα chain
-
Bulfone-PauS, S., Bulanova, E., Pohl, T., Budagian, V., Durkop, H., Ruckert, R., Kunzendorf, U., Paus, R., Krause, H. (1999) Death deflected: IL-15 inhibits TNF-_-mediated apoptosis in fibroblasts by TRAF2 recruitment to the IL-15R_ chain. FASEB J. 13, 1575-1585.
-
(1999)
FASEB J
, vol.13
, pp. 1575-1585
-
-
Bulanova, E.1
Pohl, T.2
Budagian, V.3
Durkop, H.4
Ruckert, R.5
Kunzendorf, U.6
Paus, R.7
Krause, H.8
-
47
-
-
40449100795
-
IL-15 treatment during acute simian immunodeficiency virus (SIV) infection increases viral set point and accelerates disease progression despite the induction of stronger SIV-specific CD8_ T cell responses
-
Mueller, Y. M., Do, D. H., Altork, S. R., Artlett, C. M., Gracely, E. J., Katsetos, C. D., Legido, A., Villinger, F., Altman, J. D., Brown, C. R., Lewis, M. G., Katsikis, P. D. (2008) IL-15 treatment during acute simian immunodeficiency virus (SIV) infection increases viral set point and accelerates disease progression despite the induction of stronger SIV-specific CD8_ T cell responses. J. Immunol. 180, 350-360.
-
(2008)
J. Immunol
, vol.180
, pp. 350-360
-
-
Mueller, Y.M.1
Do, D.H.2
Altork, S.R.3
Artlett, C.M.4
Gracely, E.J.5
Katsetos, C.D.6
Legido, A.7
Villinger, F.8
Altman, J.D.9
Brown, C.R.10
Lewis, M.G.11
Katsikis, P.D.12
-
48
-
-
0031910034
-
Induction of HIV-1 replication by type 1-like cytokines, interleukin (IL)-12 and IL-15: Effect on viral transcriptional activation, cellular proliferation, and endogenous cytokine production
-
Al-Harthi, L., Roebuck, K. A., Landay, A. (1998) Induction of HIV-1 replication by type 1-like cytokines, interleukin (IL)-12 and IL-15: effect on viral transcriptional activation, cellular proliferation, and endogenous cytokine production. J. Clin. Immunol. 18, 124-131.
-
(1998)
J. Clin. Immunol
, vol.18
, pp. 124-131
-
-
Al-Harthi, L.1
Roebuck, K.A.2
Landay, A.3
-
49
-
-
77949565615
-
Plasma cytokine levels during acute HIV-1 infection predict HIV disease progression
-
Roberts, L., Passmore, J., Williamson, C., Little, F., Babell, L., Mlisana, K., Burgers, W., van Loggerenberg, F., Walzl, G., Djoba Siawaya, J., Karim, Q., Karim, S. (2010) Plasma cytokine levels during acute HIV-1 infection predict HIV disease progression. AIDS 24, 819-831.
-
(2010)
AIDS
, vol.24
, pp. 819-831
-
-
Roberts, L.1
Passmore, J.2
Williamson, C.3
Little, F.4
Babell, L.5
Mlisana, K.6
Burgers, W.7
van Loggerenberg, F.8
Walzl, G.9
Siawaya, J.D.10
Karim, Q.11
Karim, S.12
-
50
-
-
33947198681
-
Interleukin-15 but not interleukin-7 abrogates vaccine-induced decrease in virus level in simian immunodeficiency virus mac251-infected macaques
-
Hryniewicz, A., Price, D. A., Moniuszko, M., Boasso, A., Edghill-Spano, Y., West, S. M., Venzon, D., Vaccari, M., Tsai, W. P., Tryniszewska, E., Nacsa, J., Villinger, F., Ansari, A. A., Trindade, C. J., Morre, M., Brooks, D., Arlen, P., Brown, H. J., Kitchen, C. M., Zack, J. A., Douek, D. C., Shearer, G. M., Lewis, M. G., Koup, R. A., Franchini, G. (2007) Interleukin-15 but not interleukin-7 abrogates vaccine-induced decrease in virus level in simian immunodeficiency virus mac251-infected macaques. J. Immunol. 178, 3492-3504.
-
(2007)
J. Immunol
, vol.178
, pp. 3492-3504
-
-
Hryniewicz, A.1
Price, D.A.2
Moniuszko, M.3
Boasso, A.4
Edghill-Spano, Y.5
West, S.M.6
Venzon, D.7
Vaccari, M.8
Tsai, W.P.9
Tryniszewska, E.10
Nacsa, J.11
Villinger, F.12
Ansari, A.A.13
Trindade, C.J.14
Morre, M.15
Brooks, D.16
Arlen, P.17
Brown, H.J.18
Kitchen, C.M.19
Zack, J.A.20
Douek, D.C.21
Shearer, G.M.22
Lewis, M.G.23
Koup, R.A.24
Franchini, G.25
more..
-
51
-
-
61849154036
-
Coimmunization with IL-15 enhances cellular immune responses induced by a vif-deleted simian immunodeficiency virus proviral DNA vaccine and confers partial protection against vaginal challenge with SIVmac251
-
Dubie, R. A., Maksaereekul, S., Shacklett, B. L., Lemongello, D., Cole, K. S., Villinger, F., Blozis, S. A., Luciw, P. A., Sparger, E. E. (2009) Coimmunization with IL-15 enhances cellular immune responses induced by a vif-deleted simian immunodeficiency virus proviral DNA vaccine and confers partial protection against vaginal challenge with SIVmac251. Virology 386, 109-121.
-
(2009)
Virology
, vol.386
, pp. 109-121
-
-
Dubie, R.A.1
Maksaereekul, S.2
Shacklett, B.L.3
Lemongello, D.4
Cole, K.S.5
Villinger, F.6
Blozis, S.A.7
Luciw, P.A.8
Sparger, E.E.9
-
52
-
-
1342302808
-
Teaching tired T cells to fight HIV: Time to test IL-15 for immunotherapy?
-
Mastroianni, C. M., d'Ettorre, G., Forcina, G., Vullo, V. (2004) Teaching tired T cells to fight HIV: time to test IL-15 for immunotherapy? Trends Immunol. 25, 121-125.
-
(2004)
Trends Immunol
, vol.25
, pp. 121-125
-
-
Mastroianni, C.M.1
D'ettorre, G.2
Forcina, G.3
Vullo, V.4
-
53
-
-
10744233141
-
Interleukin-15 modulates interferon-γ and β chemokine production in patients with HIV infection: Implications for immune-based therapy
-
Forcina, G., D'Ettorre, G., Mastroianni, C. M., Carnevalini, M., Scorzolini, L., Ceccarelli, G., D'Agostino, C., Lichtner, M., Massetti, A. P., Vullo, V. (2004) Interleukin-15 modulates interferon-_ and _-chemokine production in patients with HIV infection: implications for immune-based therapy. Cytokine 25, 283-290.
-
(2004)
Cytokine
, vol.25
, pp. 283-290
-
-
Forcina, G.1
D'ettorre, G.2
Mastroianni, C.M.3
Carnevalini, M.4
Scorzolini, L.5
Ceccarelli, G.6
D'agostino, C.7
Lichtner, M.8
Massetti, A.P.9
Vullo, V.10
-
54
-
-
70449731193
-
High concentrations of interleukin 15 in breast milk are associated with protection against postnatal HIV transmission
-
Walter, J., Ghosh, M. K., Kuhn, L., Semrau, K., Sinkala, M., Kankasa, C., Thea, D. M., Aldrovandi, G. M. (2009) High concentrations of interleukin 15 in breast milk are associated with protection against postnatal HIV transmission. J. Infect. Dis. 200, 1498-1502.
-
(2009)
J. Infect. Dis
, vol.200
, pp. 1498-1502
-
-
Walter, J.1
Ghosh, M.K.2
Kuhn, L.3
Semrau, K.4
Sinkala, M.5
Kankasa, C.6
Thea, D.M.7
Aldrovandi, G.M.8
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