A mechanism for pituitary-resistance to thyroid hormone (PRTH) syndrome: A loss in cooperative coactivator contacts by thyroid hormone receptor (TR)β 2

Molecular Endocrinology

Volumn 25, Issue 7, 2011, Pages 1111-1125

  Lee, Sangho ^a,b   Young, Briana M ^a   Wan, Wei ^a,c   Chan, Ivan H ^a,d   Privalsky, Martin L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b EMORY UNIVERSITY   (United States)

^c TEXAS A AND M UNIVERSITY   (United States)

^d MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; LIOTHYRONINE; THYROID HORMONE RECEPTOR BETA; THYROID HORMONE RECEPTOR BETA 1; THYROID HORMONE RECEPTOR BETA 2; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; FEEDBACK SYSTEM; GENE MUTATION; GENETIC TRANSCRIPTION; HOMEOSTASIS; HORMONE BINDING; PITUITARY RESISTANCE TO THYROID HORMONE SYNDROME; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; THYROID DISEASE; WILD TYPE;

AMINO ACID MOTIFS; ARGININE; CELL LINE; GENES, REPORTER; HUMANS; IMMOBILIZED PROTEINS; LUCIFERASES; MUTATION, MISSENSE; NUCLEAR RECEPTOR COACTIVATOR 1; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; RESPONSE ELEMENTS; SURFACE PROPERTIES; THYROID HORMONE RECEPTORS BETA; THYROID HORMONE RESISTANCE SYNDROME; TRANSCRIPTION, GENETIC;

EID: 79959815855     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2010-0448     Document Type: Article

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