A natural compound, methyl angolensate, induces mitochondrial pathway of apoptosis in Daudi cells

Investigational New Drugs

Volumn 29, Issue 4, 2011, Pages 583-592

  Chiruvella, Kishore K ^a   Raghavan, Sathees C ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

Antitumor drugs; Burkitt's lymphoma; Cancer therapeutics; Chemotherapy; Cytotoxicity; DNA damage; Double strand breaks

Indexed keywords

KU ANTIGEN; KU80 ANTIGEN; METHYLANGOLENSATE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NUCLEIC ACID BINDING PROTEIN; REACTIVE OXYGEN METABOLITE; TRITERPENOID; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BURKITT LYMPHOMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DAUDI CELL; DNA FRAGMENTATION; DOUBLE STRANDED DNA BREAK; DRUG CYTOTOXICITY; HUMAN; HUMAN CELL; LYMPHOMA CELL; LYMPHOMA CELL LINE; MEDICINAL PLANT; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; SOYMIDA FEBRIFUGA;

ANNEXIN A5; APOPTOSIS; BIOLOGICAL PRODUCTS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; DNA DAMAGE; DNA REPAIR ENZYMES; FLOW CYTOMETRY; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; PROPIDIUM; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TIME FACTORS; TRITERPENES; UP-REGULATION;

EID: 79959771156     PISSN: 01676997     EISSN: 15730646     Source Type: Journal    
DOI: 10.1007/s10637-010-9393-7     Document Type: Article

References (39)

1. Rowley JD (2001) Chromosome translocations: dangerous liaisons revisited. Nat Rev Cancer 1:245-250
2. Nambiar M, Kari V, Raghavan SC (2008) Chromosomal translocations in cancer. Biochim Biophys Acta 1786(2):139-152
3. Devesa SS, Fears T (1992) Non-Hodgkin's lymphoma time trends: United States and international data. Cancer Res 52(19 Suppl):5432s-5440s
4. Raghavan SC, Lieber MR (2006) DNA structures at chromosomal translocation sites. Bioessays 28(5):480-494 (Pubitemid 43668063)
5. Lieber MR, Yu K, Raghavan SC (2006) Roles of nonhomologous DNA end joining, V(D)J recombination, and class switch recombination in chromosomal translocations. DNA Repair (Amst) 5(9-10):1234-1245
6. Lieber MR (1993) in The Causes and Consequences of Chromosomal Translocations. Kirsch I (ed). CRC Press, p 239-275
7. Emmanouilides C, Jazirehi AR, Bonavida B (2002) Rituximab-mediated sensitization of B-non-Hodgkin's lymphoma (NHL) to cytotoxicity induced by paclitaxel, gemcitabine, and vinorelbine. Cancer Biother Radiopharm 17(6):621-630 (Pubitemid 36025943)
8. Cline JM, Hughes CL Jr (1998) Phytochemicals for the prevention of breast and endometrial cancer. Cancer Treat Res 94:107-134
9. Liby KT, Yore MM, Sporn MB (2007) Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer. Nat Rev Cancer 7(5):357-369 (Pubitemid 46652485)
10. Place AE et al (2003) The novel synthetic triterpenoid, CDDO-imidazolide, inhibits inflammatory response and tumor growth in vivo. Clin Cancer Res 9(7):2798-2806 (Pubitemid 36842126)
11. Chiruvella KK et al (2008) Methyl angolensate, a natural tetranortriterpenoid induces intrinsic apoptotic pathway in leukemic cells. FEBS Lett 582(29):4066-4076
12. Orisadipe A et al (2001) Spasmolytic activity of methyl angolensate: a triterpenoid isolated from Entandrophragma angolense. Biol Pharm Bull 24(4):364-367 (Pubitemid 32377603)
13. Penido C et al (2006) Inhibition of allergen-induced eosinophil recruitment by natural tetranortriterpenoids is mediated by the suppression of IL-5, CCL11/eotaxin and NFkappaB activation. Int Immunopharmacol 6(2):109-121 (Pubitemid 43054919)
14. Abdelgaleil SA, Hashinaga F, Nakatani M (2005) Antifungal activity of limonoids from Khaya ivorensis. Pest Manag Sci 61 (2):186-190 (Pubitemid 40115990)
15. Chiruvella KK et al (2007) Phytochemical and antimicrobial studies of methyl angolensate and luteolin-7-O-glucoside isolated from callus cultures of soymida febrifuga. Int J Biomed Sci 3:269-278
16. Gowda NR et al (2009) Synthesis and biological evaluation of novel 1-(4-methoxyphenethyl)-1H-benzimidazole-5-carboxylic acid derivatives and their precursors as antileukemic agents. Bioorg Med Chem Lett 19(16):4594-4600
17. Korzeniewski C, Callewaert DM (1983) An enzyme-release assay for natural cytotoxicity. J Immunol Methods 64(3):313-320 (Pubitemid 14243095)
18. Kavitha CV et al (2009) Novel derivatives of spirohydantoin induce growth inhibition followed by apoptosis in leukemia cells. Biochem Pharmacol 77(3):348-363
19. Shahabuddin MS et al (2009) A novel DNAintercalator, butylaminopyrimido[4′,5′:4,5]selenolo(2,3-b)quinoline, induces cell cycle arrest and apoptosis in leukemic cells. Invest New Drugs
20. Li ZX et al (2009) Curcumin induces apoptosis and inhibits growth of human Burkitt's lymphoma in xenograft mouse model. Mol Cells 27(3):283-289
21. Frankfurt OS, Krishan A (2003) Apoptosis-based drug screening and detection of selective toxicity to cancer cells. Anticancer Drugs 14(7):555-561 (Pubitemid 37083161)
22. Castrillo A et al (2001) Inhibition of the nuclear factor kappa B (NF-kappa B) pathway by tetracyclic kaurene diterpenes in macrophages. Specific effects on NF-kappa B-inducing kinase activity and on the coordinate activation of ERK and p38 MAPK. J Biol Chem 276(19):15854-15860
23. Lee JH et al (2002) Kaurane diterpene, kamebakaurin, inhibits NF-kappa B by directly targeting the DNA-binding activity of p50 and blocks the expression of antiapoptotic NF-kappa B target genes. J Biol Chem 277(21):18411-18420
24. Pulvertaft JV (1964) Cytology of Burkitt's Tumour (African Lymphoma). Lancet 1(7327):238-240
25. Lin YJ et al (2009) Puerariae radix isoflavones and their metabolites inhibit growth and induce apoptosis in breast cancer cells. Biochem Biophys Res Commun 378(4):683-688
26. Liu LF et al (2004) Action of solamargine on human lung cancer cells-enhancement of the susceptibility of cancer cells to TNFs. FEBS Lett 577(1-2):67-74
27. Reyes FJ et al (2006) (2Alpha, 3beta)-2, 3-dihydroxyolean-12-en-28-oic acid, a new natural triterpene from Olea europea, induces caspase dependent apoptosis selectively in colon adenocarcinoma cells. FEBS Lett 580(27):6302-6310 (Pubitemid 44794373)
28. Roy HK et al (2001) Polyethylene glycol induces apoptosis in HT-29 cells: potential mechanism for chemoprevention of colon cancer. FEBS Lett 496(2-3):143-146 (Pubitemid 32441815)
29. Michaelis M et al (2010) Anti-cancer effects of artesunate in a panel of chemoresistant neuroblastoma cell lines. Biochem Pharmacol 79(2):130-136
30. Kumar A et al (2008)Growth inhibition and induction of apoptosis in MCF-7 breast cancer cells by a new series of substituted-1, 3, 4-oxadiazole derivatives. Invest New Drugs 26(5):425-435
31. Kim SY et al (2007) Surfactin from Bacillus subtilis displays antiproliferative effect via apoptosis induction, cell cycle arrest and survival signaling suppression. FEBS Lett 581(5):865-871
32. Dassonneville L et al (2000) Cytotoxicity and cell cycle effects of the plant alkaloids cryptolepine and neocryptolepine: relation to drug-induced apoptosis. Eur J Pharmacol 409(1):9-18
33. Koopman G et al (1994) Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood 84(5):1415-1420 (Pubitemid 24273007)
34. Tan ML et al (2005) Methanolic extract of Pereskia bleo (Kunth) DC. (Cactaceae) induces apoptosis in breast carcinoma, T47-D cell line. J Ethnopharmacol 96(1-2):287-294 (Pubitemid 39575062)
35. Chung YM, Bae YS, Lee SY (2003) Molecular ordering of ROS production, mitochondrial changes, and caspase activation during sodium salicylate-induced apoptosis. Free Radic Biol Med 34 (4):434-442 (Pubitemid 36140168)
36. Ikai T et al (2006) Magnolol-induced apoptosis is mediated via the intrinsic pathway with release of AIF from mitochondria in U937 cells. Biol Pharm Bull 29(12):2498-2501 (Pubitemid 44885876)
37. Ohguchi K et al (2005) Vaticanol C-induced cell death is associated with inhibition of pro-survival signaling in HL60 human leukemia cell line. Biosci Biotechnol Biochem 69(2):353-356 (Pubitemid 40413257)
38. Nakagawa Yet al (2005) A potent apoptosis-inducing activity of a sesquiterpene lactone, arucanolide, in HL60 cells: a crucial role of apoptosis-inducing factor. J Pharmacol Sci 97(2):242-252
39. Deriano L et al (2005) Human chronic lymphocytic leukemia B cells can escape DNA damage-induced apoptosis through the nonhomologous end-joining DNA repair pathway. Blood 105 (12):4776-4783 (Pubitemid 40807303)