-
2
-
-
0033623296
-
Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II a receptor member of the TGF-b family
-
Thomson JR, Machado RD, Pauciulo MW et al. Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-b family. J. Med. Genet. 37(10), 741-745 (2000
-
(2000)
J. Med. Genet.
, vol.37
, Issue.10
, pp. 741-745
-
-
Thomson, J.R.1
Machado, R.D.2
Pauciulo, M.W.3
-
3
-
-
0035163071
-
BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension
-
DOI 10.1086/316947
-
Machado RD, Pauciulo MW, Thomson JR et al. BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension. Am. J. Hum. Genet. 68(1), 92-102 (2001 (Pubitemid 32048364)
-
(2001)
American Journal of Human Genetics
, vol.68
, Issue.1
, pp. 92-102
-
-
Machado, R.D.1
Pauciulo, M.W.2
Thomson, J.R.3
Lane, K.B.4
Morgan, N.V.5
Wheeler, L.6
Phillips III, J.A.7
Newman, J.8
Williams, D.9
Galie, N.10
Manes, A.11
McNeil, K.12
Yacoub, M.13
Mikhail, G.14
Rogers, P.15
Corris, P.16
Humbert, M.17
Donnai, D.18
Martensson, G.19
Tranebjaerg, L.20
Loyd, J.E.21
Trembath, R.C.22
Nichols, W.C.23
more..
-
4
-
-
9144219585
-
Molecular and functional analysis identifies ALK-1 as the predominant cause of pulmonary hypertension related to hereditary haemorrhagic telangiectasia
-
Harrison RE, Flanagan JA, Sankelo M et al. Molecular and functional analysis identifies ALK-1 as the predominant cause of pulmonary hypertension related to hereditary haemorrhagic telangiectasia. J. Med. Genet. 40(12), 865-871 (2003 (Pubitemid 38117534)
-
(2003)
Journal of Medical Genetics
, vol.40
, Issue.12
, pp. 865-871
-
-
Harrison, R.E.1
Flanagan, J.A.2
Sankelo, M.3
Abdalla, S.A.4
Rowell, J.5
Machado, R.D.6
Elliott, C.G.7
Robbins, I.M.8
Olschewski, H.9
McLaughlin, V.10
Gruenig, E.11
Kermeen, F.12
Laitinen, T.13
Morrell, N.W.14
Halme, M.15
Raisanen-Sakolowski16
Trembath, R.C.17
-
5
-
-
0345059064
-
2B receptor loss of function mutation in a patient with fenfluramine-associated primary pulmonary hypertension
-
DOI 10.1016/j.cardiores.2003.09.015
-
Blanpain C, Le Poul E, Parma J et al. Serotonin 5-HT(2B) receptor loss of function mutation in a patient with fenfluramine-associated primary pulmonary hypertension. Cardiovasc. Res. 60(3), 518-528 (2003 (Pubitemid 37501109)
-
(2003)
Cardiovascular Research
, vol.60
, Issue.3
, pp. 518-528
-
-
Blanpain, C.1
Le Poul, E.2
Parma, J.3
Knoop, C.4
Detheux, M.5
Parmentier, M.6
Vassart, G.7
Abramowicz, M.J.8
-
6
-
-
34447566110
-
The burden of pulmonary hypertension
-
DOI 10.1183/09031936.00055407
-
Humbert M. The burden of pulmonary hypertension. Eur. Respir. J. 30(1), 1-2 (2007 (Pubitemid 47073996)
-
(2007)
European Respiratory Journal
, vol.30
, Issue.1
, pp. 1-2
-
-
Humbert, M.1
-
7
-
-
0025837793
-
Survival in patients with primary pulmonary hypertension results from a national prospective registry
-
D'Alonzo GE, Barst RJ, Ayres SM et al. Survival in patients with primary pulmonary hypertension. Results from a national prospective registry. Ann. Intern. Med. 115(5), 343-349 (1991
-
(1991)
Ann. Intern. Med.
, vol.115
, Issue.5
, pp. 343-349
-
-
D'Alonzo, G.E.1
Barst, R.J.2
Ayres, S.M.3
-
8
-
-
33646269035
-
Pulmonary arterial hypertension in France: Results from a national registry
-
Humbert M, Sitbon O, Chaouat A et al. Pulmonary arterial hypertension in France: results from a national registry. Am. J. Respir. Crit. Care Med. 173(9), 1023-1030 (2006
-
(2006)
Am. J. Respir. Crit. Care Med.
, vol.173
, Issue.9
, pp. 1023-1030
-
-
Humbert, M.1
Sitbon, O.2
Chaouat, A.3
-
10
-
-
77954758530
-
Survival in patients with idiopathic familial and anorexigen-associated pulmonary arterial hypertension in the modern management era
-
Humbert M, Sitbon O, Chaouat A et al. Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era. Circulation 122(2), 156-163 (2010
-
(2010)
Circulation
, vol.122
, Issue.2
, pp. 156-163
-
-
Humbert, M.1
Sitbon, O.2
Chaouat, A.3
-
11
-
-
77954759389
-
Predicting survival in pulmonary arterial hypertension: Insights from the registry to evaluate early and long-term pulmonary arterial hypertension disease management reveal
-
Benza RL, Miller DP, Gomberg-Maitland M et al. Predicting survival in pulmonary arterial hypertension: insights from the Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEALCirculation 122(2), 164-172 (2010).
-
(2010)
Circulation
, vol.122
, Issue.2
, pp. 164-172
-
-
Benza, R.L.1
Miller, D.P.2
Gomberg-Maitland, M.3
-
12
-
-
0026628265
-
An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension
-
Christman BW, McPherson CD, Newman JH et al. An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension. N. Engl. J. Med. 327(2), 70-75 (1992
-
(1992)
N. Engl. J. Med.
, vol.327
, Issue.2
, pp. 70-75
-
-
Christman, B.W.1
McPherson, C.D.2
Newman, J.H.3
-
13
-
-
0034047308
-
Sildenafil is a pulmonary vasodilator in awake lambs with acute pulmonary hypertension
-
Weimann J, Ullrich R, Hromi J et al. Sildenafil is a pulmonary vasodilator in awake lambs with acute pulmonary hypertension. Anesthesiology 92(6), 1702-1712 (2000 (Pubitemid 30412491)
-
(2000)
Anesthesiology
, vol.92
, Issue.6
, pp. 1702-1712
-
-
Weimann, J.1
Ullrich, R.2
Hromi, J.3
Fujino, Y.4
Clark, M.W.H.5
Bloch, K.D.6
Zapol, W.M.7
-
14
-
-
0035942990
-
Sildenafil inhibits hypoxia-induced pulmonary hypertension
-
Zhao L, Mason NA, Morrell NW et al. Sildenafil inhibits hypoxia-induced pulmonary hypertension. Circulation 104(4), 424-428 (2001 (Pubitemid 32678272)
-
(2001)
Circulation
, vol.104
, Issue.4
, pp. 424-428
-
-
Zhao, L.1
Mason, N.A.2
Morrell, N.W.3
Kojonazarov, B.4
Sadykov, A.5
Maripov, A.6
Mirrakhimov, M.M.7
Aldashev, A.8
Wilkins, M.R.9
-
15
-
-
0037149718
-
Bosentan therapy for pulmonary arterial hypertension
-
DOI 10.1056/NEJMoa012212
-
Rubin LJ, Badesch D, Barst RJ et al. Bosentan therapy for pulmonary arterial hypertension. N. Engl. J. Med. 346, 896-903 (2002 (Pubitemid 34984638)
-
(2002)
New England Journal of Medicine
, vol.346
, Issue.12
, pp. 896-903
-
-
Rubin, L.J.1
Badesch, D.B.2
Barst, R.J.3
Galie, N.4
Black, C.M.5
Keogh, A.6
Pulido, T.7
Frost, A.8
Roux, S.9
Leconte, I.10
Landzberg, M.11
Simonneau, G.12
-
16
-
-
46449124591
-
Ambrisentan for the treatment of pulmonary arterial hypertension
-
Galie N, Olschewski H, Oudiz RJ et al. Ambrisentan for the treatment of pulmonary arterial hypertension. Circulation 117, 3010-3019 (2008
-
(2008)
Circulation
, vol.117
, pp. 3010-3019
-
-
Galie, N.1
Olschewski, H.2
Oudiz, R.J.3
-
17
-
-
26444534291
-
Sildenafil citrate therapy for pulmonary arterial hypertension
-
DOI 10.1056/NEJMoa050010
-
Galie N, Ghofrani HA, Torbicki A et al. Sildenafil citrate therapy for pulmonary arterial hypertension. N. Engl. J. Med. 353, 2148-2157 (2005 (Pubitemid 41653106)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.20
, pp. 2148-2157
-
-
Galie, N.1
Ghofrani, H.A.2
Torbicki, A.3
Barst, R.J.4
Rubin, L.J.5
Badesch, D.6
Fleming, T.7
Parpia, T.8
Burgess, G.9
Branzi, A.10
Grimminger, F.11
Kurzyna, M.12
Simonneau, G.13
-
18
-
-
67649523052
-
Tadalafil therapy for pulmonary arterial hypertension
-
Galie N, Brundage BH, Ghofrani HA et al. Tadalafil therapy for pulmonary arterial hypertension. Circulation 119, 2894-2903 (2009
-
(2009)
Circulation
, vol.119
, pp. 2894-2903
-
-
Galie, N.1
Brundage, B.H.2
Ghofrani, H.A.3
-
19
-
-
62749192201
-
A meta-analysis of randomized controlled trials in pulmonary arterial hypertension
-
Galié N, Manes A, Negro L, Palazzini M, Bacchi-Reggiani ML, Branzi A. A meta-analysis of randomized controlled trials in pulmonary arterial hypertension. Eur. Heart J. 30(4), 394-403 (2009
-
(2009)
Eur. Heart J.
, vol.30
, Issue.4
, pp. 394-403
-
-
Galié, N.1
Manes, A.2
Negro, L.3
Palazzini, M.4
Bacchi-Reggiani, M.L.5
Branzi, A.6
-
20
-
-
0030031888
-
A comparison of continuous intravenous epoprostenol prostacyclin with conventional therapy for primary pulmonary hypertension the primary pulmonary hypertension study group
-
Barst RJ, Rubin LJ, Long WA et al. A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. The Primary Pulmonary Hypertension Study Group. N. Engl. J. Med. 334(5), 296-302 (1996
-
(1996)
N. Engl. J. Med.
, vol.334
, Issue.5
, pp. 296-302
-
-
Barst, R.J.1
Rubin, L.J.2
Long, W.A.3
-
21
-
-
67649588196
-
Updated evidence-based treatment algorithm in pulmonary arterial hypertension
-
Barst RJ, Gibbs JS, Ghofrani HA et al. Updated evidence-based treatment algorithm in pulmonary arterial hypertension. J. Am. Coll. Cardiol. 54(Suppl. 1), S78-S84 (2009
-
(2009)
J. Am. Coll. Cardiol.
, vol.54
, Issue.1
-
-
Barst, R.J.1
Gibbs, J.S.2
Ghofrani, H.A.3
-
22
-
-
66549127501
-
ACCF/AHA 2009 expert consensus document on pulmonary hypertension
-
A report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: developed in collaboration with the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association.
-
McLaughlin VV, Archer SL, Badesch DB et al. ACCF/AHA 2009 expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: developed in collaboration with the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association. Circulation 119(16), 2250-2294 (2009
-
(2009)
Circulation
, vol.119
, Issue.16
, pp. 2250-2294
-
-
McLaughlin, V.V.1
Archer, S.L.2
Badesch, D.B.3
-
23
-
-
4544383466
-
Combination of bosentan with epoprostenol in pulmonary arterial hypertension: BREATHE-2
-
DOI 10.1183/09031936.04.00028404
-
Humbert M, Barst RJ, Robbins IM et al. Combination of Bosentan with Epoprostenol in Pulmonary Arterial Hypertension: breathe-2. Eur. Respir. J. 24, 353-359 (2004 (Pubitemid 39232254)
-
(2004)
European Respiratory Journal
, vol.24
, Issue.3
, pp. 353-359
-
-
Humbert, M.1
Barst, R.J.2
Robbins, I.M.3
Channick, R.N.4
Galie, N.5
Boonstra, A.6
Rubin, L.J.7
Horn, E.M.8
Manes, A.9
Simonneau, G.10
-
24
-
-
33845526777
-
Randomized study of adding inhaled iloprost to existing bosentan in pulmonary arterial hypertension
-
DOI 10.1164/rccm.200603-358OC
-
Mclaughlin VV, Oudiz RJ, Frost A et al. Randomized study of adding inhaled iloprost to existing bosentan in pulmonary arterial hypertension. Am. J. Respir. Crit. Care Med. 174, 1257-1263 (2006 (Pubitemid 44924827)
-
(2006)
American Journal of Respiratory and Critical Care Medicine
, vol.174
, Issue.11
, pp. 1257-1263
-
-
McLaughlin, V.V.1
Oudiz, R.J.2
Frost, A.3
Tapson, V.F.4
Murali, S.5
Channick, R.N.6
Badesch, D.B.7
Barst, R.J.8
Hsu, H.H.9
Rubin, L.J.10
-
25
-
-
77952301237
-
Addition of inhaled treprostinil to oral therapy for pulmonary arterial hypertension: A randomized controlled clinical trial
-
Mclaughlin VV, Benza RL, Rubin LJ et al. Addition of inhaled treprostinil to oral therapy for pulmonary arterial hypertension: a randomized controlled clinical trial. J. Am. Coll. Cardiol. 55, 1915-1922 (2010
-
(2010)
J. Am. Coll. Cardiol.
, vol.55
, pp. 1915-1922
-
-
Mclaughlin, V.V.1
Benza, R.L.2
Rubin, L.J.3
-
26
-
-
23744496842
-
Bosentan improves exercise tolerance and Tei index in patients with pulmonary hypertension and prostanoid therapy
-
DOI 10.1378/chest.128.2.709
-
Seyfarth HJ, Pankau H, Hammerschmidt S, Schauer J, Wirtz H, Winkler J. Bosentan improves exercise tolerance and tei index in patients with pulmonary hypertension and prostanoid therapy. Chest 128, 709-713 (2005 (Pubitemid 41140500)
-
(2005)
Chest
, vol.128
, Issue.2
, pp. 709-713
-
-
Seyfarth, H.-J.1
Pankau, H.2
Hammerschmidt, S.3
Schauer, J.4
Wirtz, H.5
Winkler, J.6
-
27
-
-
54549125950
-
Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: A randomized trial
-
Simonneau G, Rubin LJ, Galie N et al. Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: a randomized trial. Ann. Intern. Med. 149, 521-530 (2008
-
(2008)
Ann. Intern. Med.
, vol.149
, pp. 521-530
-
-
Simonneau, G.1
Rubin, L.J.2
Galie, N.3
-
28
-
-
0026722911
-
Molecular biology of the natriuretic peptides and their receptors
-
Koller KJ, Goeddel DV. Molecular biology of the natriuretic peptides and their receptors. Circulation 86(4), 1081-1088 (1992
-
(1992)
Circulation
, vol.86
, Issue.4
, pp. 1081-1088
-
-
Koller, K.J.1
Goeddel, D.V.2
-
29
-
-
19444363531
-
Biology of natriuretic peptides and their receptors
-
DOI 10.1016/j.peptides.2004.09.024, PII S0196978105000781
-
Pandey KN. Biology of natriuretic peptides and their receptors. Peptides 26(6), 901-932 (2005 (Pubitemid 40725366)
-
(2005)
Peptides
, vol.26
, Issue.SPEC. ISS. 6
, pp. 901-932
-
-
Pandey, K.N.1
-
30
-
-
0000707453
-
Nitric oxide activates guanylate cyclase and increases guanosine 3':5'-cyclic monophosphate levels in various tissue preparations
-
DOI 10.1073/pnas.74.8.3203
-
Arnold WP, Mittal CK, Katsuki S, Murad F. Nitric oxide activates guanylate cyclase and increases guanosine 3́:5́-cyclic monophosphate levels in various tissue preparations. Proc. Natl. Acad. Sci. USA 74(8), 3203-3207 (1977 (Pubitemid 8180317)
-
(1977)
Proceedings of the National Academy of Sciences of the United States of America
, vol.74
, Issue.8
, pp. 3203-3207
-
-
Arnold, W.P.1
Mittal, C.K.2
Katsuki, S.3
Murad, F.4
-
31
-
-
33847410021
-
The nitric oxide/cGMP signaling pathway in pulmonary hypertension
-
DOI 10.1016/j.ccm.2006.12.002, PII S0272523106001298, Pulmonary Arterial Hypertension
-
Klinger JR. The nitric oxide/cGMP signaling pathway in pulmonary hypertension. Clin. Chest Med. 28(1), 143-167 (2007 (Pubitemid 46343758)
-
(2007)
Clinics in Chest Medicine
, vol.28
, Issue.1
, pp. 143-167
-
-
Klinger, J.R.1
-
32
-
-
0027418979
-
Inhaled nitric oxide selectively reverses human hypoxic pulmonary vasoconstriction without causing systemic vasodilation
-
Frostell CG, Blomqvist H, Hedenstierna G, Lundberg J, Zapol WM. Inhaled nitric oxide selectively reverses human hypoxic pulmonary vasoconstriction without causing systemic vasodilation. Anesthesiology 78(3), 427-435 (1993 (Pubitemid 23090476)
-
(1993)
Anesthesiology
, vol.78
, Issue.3
, pp. 427-435
-
-
Frostell, C.G.1
Blomqvist, H.2
Hedenstierna, G.3
Lundberg, J.4
Zapol, W.M.5
-
33
-
-
0028910249
-
Evidence that nitric oxide from the endothelium attenuates inherent tone in isolated pulmonary arteries from rats with hypoxic pulmonary hypertension
-
Wanstall JC, Hughes IE, O'Donnell SR. Evidence that nitric oxide from the endothelium attenuates inherent tone in isolated pulmonary arteries from rats with hypoxic pulmonary hypertension. Br. J. Pharmacol. 114(1), 109-114 (1995
-
(1995)
Br. J. Pharmacol.
, vol.114
, Issue.1
, pp. 109-114
-
-
Wanstall, J.C.1
Hughes, I.E.2
O'Donnell, S.R.3
-
34
-
-
0028316708
-
Brain natriuretic peptide: Possible role in the modulation of hypoxic pulmonary hypertension
-
Hill NS, Klinger JR, Warburton RR, Pietras L, Wrenn DS. Brain natriuretic peptide: possible role in the modulation of hypoxic pulmonary hypertension. Am. J. Physiol. 266(3 Pt 1), L308-L315 (1994
-
(1994)
Am. J. Physiol.
, vol.266
, Issue.1-3
-
-
Hill, N.S.1
Klinger, J.R.2
Warburton, R.R.3
Pietras, L.4
Wrenn, D.S.5
-
35
-
-
0036082790
-
Targeted disruption of the gene for natriuretic peptide receptor-A worsens hypoxia-induced cardiac hypertrophy
-
Klinger JR, Warburton RR, Pietras L et al. Targeted disruption of the gene for natriuretic peptide receptor-A worsens hypoxia-induced cardiac hypertrophy. Am. J. Physiol. Heart Circulation Physiol. 282(1), H58-H65 (2002 (Pubitemid 34654134)
-
(2002)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.282
, Issue.1
-
-
Klinger, J.R.1
Warburton, R.R.2
Pietras, L.3
Oliver, P.4
Fox, J.5
Smithies, O.6
Hill, N.S.7
-
36
-
-
0033537488
-
NPR-A-deficient mice show increased susceptibility to hypoxia-induced pulmonary hypertension
-
Zhao L, Long L, Morrell NW, Wilkins MR. NPR-A-Deficient mice show increased susceptibility to hypoxia-induced pulmonary hypertension. Circulation 99(5), 605-607 (1999 (Pubitemid 29077357)
-
(1999)
Circulation
, vol.99
, Issue.5
, pp. 605-607
-
-
Zhao, L.1
Long, L.2
Morrell, N.W.3
Wilkins, M.R.4
-
37
-
-
33750057013
-
Renal hyporesponsiveness to brain natriuretic peptide: Both generation and renal activity of cGMP are decreased in patients with pulmonary hypertension
-
DOI 10.1016/j.peptides.2006.05.023, PII S0196978106002622
-
Charloux A, Chaouat A, Piquard F, Brandenberger G, Weitzenblum E, Geny B. Renal hyporesponsiveness to brain natriuretic peptide: both generation and renal activity of cGMP are decreased in patients with pulmonary hypertension. Peptides 27(11), 2993-2999 (2006 (Pubitemid 44584406)
-
(2006)
Peptides
, vol.27
, Issue.11
, pp. 2993-2999
-
-
Charloux, A.1
Chaouat, A.2
Piquard, F.3
Brandenberger, G.4
Weitzenblum, E.5
Geny, B.6
-
38
-
-
0030714983
-
Decreased nitric oxide in the exhaled air of patients with systemic sclerosis with pulmonary hypertension
-
Kharitonov SA, Cailes JB, Black CM, du Bois RM, Barnes PJ. Decreased nitric oxide in the exhaled air of patients with systemic sclerosis with pulmonary hypertension. Thorax 52(12), 1051-1055 (1997 (Pubitemid 27515784)
-
(1997)
Thorax
, vol.52
, Issue.12
, pp. 1051-1055
-
-
Kharitonov, S.A.1
Cailes, J.B.2
Black, C.M.3
Du Bois, R.M.4
Barnes, P.J.5
-
39
-
-
21344459311
-
Molecular properties of mammalian proteins that interact with cGMP: Protein kinases, cation channels, phosphodiesterases, and multi-drug anion transporters
-
Francis SH, Blount MA, Zoraghi R, Corbin JD. Molecular properties of mammalian proteins that interact with cGMP: protein kinases, cation channels, phosphodiesterases, and multi-drug anion transporters. Front. Biosci. 10, 2097-2117 (2005 (Pubitemid 40908915)
-
(2005)
Frontiers in Bioscience
, vol.10
, Issue.SUPPL. 1
, pp. 2097-2117
-
-
Francis, S.H.1
Blount, M.A.2
Zoraghi, R.3
Corbin, J.D.4
-
40
-
-
36349033482
-
Phosphodiesterase type 5: Expanding roles in cardiovascular regulation
-
DOI 10.1161/CIRCRESAHA.107.162511, PII 0000301220071126000006
-
Kass DA, Champion HC, Beavo JA. Phosphodiesterase type 5: expanding roles in cardiovascular regulation. Circulation Res. 101(11), 1084-1095 (2007 (Pubitemid 350146434)
-
(2007)
Circulation Research
, vol.101
, Issue.11
, pp. 1084-1095
-
-
Kass, D.A.1
Champion, H.C.2
Beavo, J.A.3
-
41
-
-
0034862256
-
Invited review: cGMP-dependent protein kinase signaling mechanisms in smooth muscle: From the regulation of tone to gene expression
-
Lincoln TM, Dey N, Sellak H. Invited review: cGMP-dependent protein kinase signaling mechanisms in smooth muscle: from the regulation of tone to gene expression. J. Appl. Physiol. 91, 1421-1430 (2001). (Pubitemid 32803941)
-
(2001)
Journal of Applied Physiology
, vol.91
, Issue.3
, pp. 1421-1430
-
-
Lincoln, T.M.1
Dey, N.2
Sellak, H.3
-
42
-
-
0034108626
-
Phosphorylation of phosphodiesterase-5 by cyclic nucleotide-dependent protein kinase alters its catalytic and allosteric cGMP-binding activities
-
DOI 10.1046/j.1432-1327.2000.01297.x
-
Corbin JD, Turko IV, Beasley A, Francis SH. Phosphorylation of phosphodiesterase-5 by cyclic nucleotide-dependent protein kinase alters its catalytic and allosteric cGMP-binding activities. Eur. J. Biochem. 267, 2760-2767 (2000 (Pubitemid 30304274)
-
(2000)
European Journal of Biochemistry
, vol.267
, Issue.9
, pp. 2760-2767
-
-
Corbin, J.D.1
Turko, I.V.2
Beasley, A.3
Francis, S.H.4
-
43
-
-
31144433061
-
Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents
-
DOI 10.1016/j.pharmthera.2005.07.003, PII S0163725805001580
-
Lugnier C. Cyclic nucleotide phosphodiesterase (PDE) superfamily: a new target for the development of specific therapeutic agents. Pharmacol. Ther. 109(3), 366-398 (2006 (Pubitemid 43132818)
-
(2006)
Pharmacology and Therapeutics
, vol.109
, Issue.3
, pp. 366-398
-
-
Lugnier, C.1
-
44
-
-
77950287263
-
Cyclic nucleotide phosphodiesterases PDE and peptide motifs
-
Keravis T, Lugnier C. Cyclic nucleotide phosphodiesterases (PDE) and peptide motifs. Curr. Pharm. Des. 16(9), 1114-1125 (2010
-
(2010)
Curr. Pharm. Des.
, vol.16
, Issue.9
, pp. 1114-1125
-
-
Keravis, T.1
Lugnier, C.2
-
45
-
-
4644232338
-
Differences in hemodynamic and oxygenation responses to three different phosphodiesterase-5 inhibitors in patients with pulmonary arterial hypertension: A randomized prospective study
-
DOI 10.1016/j.jacc.2004.06.060, PII S0735109704013622
-
Ghofrani HA, Voswinckel R, Reichenberger F et al. Differences in hemodynamic and oxygenation responses to three different phosphodiesterase-5 inhibitors in patients with pulmonary arterial hypertension: a randomized prospective study. J. Am. Coll. Cardiol. 44(7), 1488-1496 (2004 (Pubitemid 39303954)
-
(2004)
Journal of the American College of Cardiology
, vol.44
, Issue.7
, pp. 1488-1496
-
-
Ghofrani, H.A.1
Voswinckel, R.2
Reichenberger, F.3
Olschewski, H.4
Haredza, P.5
Karadas, B.6
Schermuly, R.T.7
Weissmann, N.8
Seeger, W.9
Grimminger, F.10
-
46
-
-
0035962999
-
Expression of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in mouse tissues and cell lines using an antibody against the enzyme amino-terminal domain
-
DOI 10.1016/S0167-4889(01)00086-6, PII S0167488901000866
-
Giordano D, De Stefano ME, Citro G, Modica A, Giorgi M. Expression of cGMP-binding cGMP-specific phosphodiesterase (PDE-5) in mouse tissues and cell lines using an antibody against the enzyme amino-terminal domain. Biochim. Biophys. Acta. 1539, 16-27 (2001 (Pubitemid 32522866)
-
(2001)
Biochimica et Biophysica Acta - Molecular Cell Research
, vol.1539
, Issue.1-2
, pp. 16-27
-
-
Giordano, D.1
De Stefano, M.E.2
Citro, G.3
Modica, A.4
Giorgi, M.5
-
47
-
-
0030733082
-
Phosphodiesterase isoforms in the pulmonary arterial circulation of the rat: Changes in pulmonary hypertension
-
Maclean MR, Johnston ED, Mcculloch KM, Pooley L, Houslay MD, Sweeney G. Phosphodiesterase isoforms in the pulmonary arterial circulation of the rat: changes in pulmonary hypertension. J. Pharmacol. Exp. Ther. 283(2), 619-624 (1997 (Pubitemid 27514618)
-
(1997)
Journal of Pharmacology and Experimental Therapeutics
, vol.283
, Issue.2
, pp. 619-624
-
-
Maclean, M.R.1
Johnston, E.D.2
Mcculloch, K.M.3
Pooley, L.4
Houslay, M.D.5
Sweeney, G.6
-
48
-
-
0031767180
-
Chronic pulmonary hypertension increases fetal lung cGMP phosphodiesterase activity
-
Hanson KA, Ziegler JW, Rybalkin SD, Miller JW, Abman SH, Clarke WR. Chronic pulmonary hypertension increases fetal lung cGMP phosphodiesterase activity. Am. J. Physiol. 275, L931-L941 (1998
-
(1998)
Am. J. Physiol.
, vol.275
-
-
Hanson, K.A.1
Ziegler, J.W.2
Rybalkin, S.D.3
Miller, J.W.4
Abman, S.H.5
Clarke, W.R.6
-
49
-
-
12144286644
-
Clinical and haemodynamic effects of sildenafil in pulmonary hypertension: Acute and mid-term effects
-
DOI 10.1016/j.ehj.2004.01.013
-
Mikhail GW, Prasad SK, Li W et al. Clinical and haemodynamic effects of sildenafil in pulmonary hypertension: acute and mid-term effects. Eur. Heart J. 25, 431-436 (2004 (Pubitemid 38391526)
-
(2004)
European Heart Journal
, vol.25
, Issue.5
, pp. 431-436
-
-
Mikhail, G.W.1
Prasad, S.K.2
Li, W.3
Rogers, P.4
Chester, A.H.5
Bayne, S.6
Stephens, D.7
Khan, M.8
Gibbs, J.S.R.9
Evans, T.W.10
Mitchell, A.11
Yacoub, M.H.12
Gatzoulis, M.A.13
-
50
-
-
2942546140
-
Nitric oxide pathway and phosphodiesterase inhibitors in pulmonary arterial hypertension
-
DOI 10.1016/j.jacc.2004.02.031, PII S0735109704004401
-
Ghofrani HA, Pepke-Zaba J, Barbera JA et al. Nitric oxide pathway and phosphodiesterase inhibitors in pulmonary arterial hypertension. J. Am. Coll. Cardiol. 43, 68S-72S (2004 (Pubitemid 38759720)
-
(2004)
Journal of the American College of Cardiology
, vol.43
, Issue.SUPPL. 12
-
-
Ghofrani, H.A.1
Pepke-Zaba, J.2
Barbera, J.A.3
Channick, R.4
Keogh, A.M.5
Gomez-Sanchez, M.A.6
Kneussl, M.7
Grimminger, F.8
-
51
-
-
0037150158
-
Oral sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary arterial hypertension: Comparison with inhaled nitric oxide
-
DOI 10.1161/01.CIR.0000016641.12984.DC
-
Michelakis E, Tymchak W, Lien D, Webster L, Hashimoto K, Archer S. Oral sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary arterial hypertension: comparison with inhaled nitric oxide. Circulation 105(20), 2398-2403 (2002 (Pubitemid 34556392)
-
(2002)
Circulation
, vol.105
, Issue.20
, pp. 2398-2403
-
-
Michelakis, E.1
Tymchak, W.2
Lien, D.3
Webster, L.4
Hashimoto, K.5
Archer, S.6
-
52
-
-
12744261229
-
Sildenafil inhibits altitude-induced hypoxemia and pulmonary hypertension
-
Richalet JP, Gratadour P, Robach P et al. Sildenafil inhibits altitude-induced hypoxemia and pulmonary hypertension. Am. J. Respir. Crit. Care Med. 171(3), 275-281 (2005
-
(2005)
Am. J. Respir. Crit. Care Med.
, vol.171
, Issue.3
, pp. 275-281
-
-
Richalet, J.P.1
Gratadour, P.2
Robach, P.3
-
53
-
-
9144250478
-
Synergistic effects of ANP and sildenafil on cGMP levels and amelioration of acute hypoxic pulmonary hypertension
-
Preston IR, Hill NS, Gambardella LS, Warburton RR, Klinger JR. Synergistic effects of ANP and sildenafil on cGMP levels and amelioration of acute hypoxic pulmonary hypertension. Exp. Biol. Med. 229(9), 920-925 (2004 (Pubitemid 39539377)
-
(2004)
Experimental Biology and Medicine
, vol.229
, Issue.9
, pp. 920-925
-
-
Preston, I.R.1
Hill, N.S.2
Gambardella, L.S.3
Warburton, R.R.4
Klinger, J.R.5
-
54
-
-
33344459746
-
Pulmonary hemodynamic responses to brain natriuretic peptide and sildenafil in patients with pulmonary arterial hypertension
-
DOI 10.1378/chest.129.2.417
-
Klinger JR, Thaker S, Houtchens J, Preston IR, Hill NS, Farber HW. Pulmonary hemodynamic responses to brain natriuretic peptide and sildenafil in patients with pulmonary arterial hypertension. Chest 129(2), 417-425 (2006 (Pubitemid 43289864)
-
(2006)
Chest
, vol.129
, Issue.2
, pp. 417-425
-
-
Klinger, J.R.1
Thaker, S.2
Houtchens, J.3
Preston, I.R.4
Hill, N.S.5
Farber, H.W.6
-
55
-
-
18744399352
-
Pulmonary hypertension: Inhaled nitric oxide, sildenafil and natriuretic peptides
-
DOI 10.1016/j.coph.2004.12.008, PII S1471489205000457
-
Steiner MK, Preston IR, Klinger JR, Hill NS. Pulmonary hypertension: inhaled nitric oxide, sildenafil and natriuretic peptides. Curr. Opin. Pharmacol. 5(3), 245-250 (2005 (Pubitemid 40674246)
-
(2005)
Current Opinion in Pharmacology
, vol.5
, Issue.SPEC. ISS. 3
, pp. 245-250
-
-
Steiner, M.K.1
Preston, I.R.2
Klinger, J.R.3
Hill, N.S.4
-
56
-
-
0009920266
-
IC351 enhances nitric oxide-mediated relaxation of human arterial and trabecular penile smooth muscle
-
Angulo J, Gadau M, Fernandez A et al. IC351 enhances nitric oxide-mediated relaxation of human arterial and trabecular penile smooth muscle. Diabetologia 44(S1), A295 (2001
-
(2001)
Diabetologia
, vol.44
, Issue.S1
-
-
Angulo, J.1
Gadau, M.2
Fernandez, A.3
-
57
-
-
0033199357
-
Sildenafil viagra and ophthalmology
-
Marmor MF, Kessler R. Sildenafil (Viagra) and ophthalmology. Surv. Ophthalmol. 44(2), 153-162 (1999
-
(1999)
Surv. Ophthalmol.
, vol.44
, Issue.2
, pp. 153-162
-
-
Marmor, M.F.1
Kessler, R.2
-
59
-
-
0037451871
-
Design, synthesis and biological activity of β-carboline-based type-5 phosphodiesterase inhibitors
-
DOI 10.1016/S0960-894X(03)00159-8
-
Maw GN, Allerton CM, Gbekor E, Million WA. Design, synthesis and biological activity of b-carboline-based type-5 phosphodiesterase inhibitors. Bioorg. Med. Chem. Lett. 13(8), 1425-1428 (2003 (Pubitemid 36369181)
-
(2003)
Bioorganic and Medicinal Chemistry Letters
, vol.13
, Issue.8
, pp. 1425-1428
-
-
Maw, G.N.1
Allerton, C.M.N.2
Gbekor, E.3
Million, W.A.4
-
60
-
-
18744409801
-
Phosphodiesterase 11 (PDE11) regulation of spermatozoa physiology
-
DOI 10.1038/sj.ijir.3901307
-
Wayman C, Phillips S, Lunny C et al. Phosphodiesterase 11 (PDE-11) regulation of spermatozoa physiology. Int. J. Impot. Res. 17(3), 216-223 (2005 (Pubitemid 40675501)
-
(2005)
International Journal of Impotence Research
, vol.17
, Issue.3
, pp. 216-223
-
-
Wayman, C.1
Phillips, S.2
Lunny, C.3
Webb, T.4
Fawcett, L.5
Baxendale, R.6
Burgess, G.7
-
61
-
-
33644925565
-
Tadalafil pharmacokinetics in healthy subjects
-
DOI 10.1111/j.1365-2125.2005.02553.x
-
Forgue ST, Patterson BE, Bedding AW et al. Tadalafil pharmacokinetics in healthy subjects. Br. J. Clin. Pharmacol. 61(3), 280-288 (2006 (Pubitemid 43382627)
-
(2006)
British Journal of Clinical Pharmacology
, vol.61
, Issue.3
, pp. 280-288
-
-
Forgue, S.T.1
Patterson, B.E.2
Bedding, A.W.3
Payne, C.D.4
Phillips, D.L.5
Wrishko, R.E.6
Mitchell, M.I.7
-
62
-
-
4043144910
-
®) in men with erectile dysfunction
-
DOI 10.1016/j.eururo.2004.04.026, PII S0302283804002374
-
Skoumal R, Chen J, Kula K et al. Efficacy and treatment satisfaction with on-demand tadalafil (Cialis) in men with erectile dysfunction. Eur. Urol. 46(3), 362-369 (2004 (Pubitemid 39078572)
-
(2004)
European Urology
, vol.46
, Issue.3
, pp. 362-369
-
-
Skoumal, R.1
Chen, J.2
Kula, K.3
Breza, J.4
Calomfirescu, N.5
Basson, B.R.6
Kopernicky, V.7
-
63
-
-
33747694337
-
Prospective, randomized, open-label, fixed-dose, crossover study to establish preference of patients with erectile dysfunction after taking the three PDE-5 inhibitors
-
DOI 10.1111/j.1743-6109.2006.00297.x
-
Tolrá JR, Campaña JM, Ciutat LF, Miranda EF. Prospective, randomized, open-label, fixed-dose, crossover study to establish preference of patients with erectile dysfunction after taking the three PDE-5 inhibitors. J. Sex Med. 3(5), 901-909 (2006 (Pubitemid 44269546)
-
(2006)
Journal of Sexual Medicine
, vol.3
, Issue.5
, pp. 901-909
-
-
Tolra, J.R.1
Campana, J.M.C.2
Ciutat, L.F.3
Miranda, E.F.4
-
64
-
-
10744233302
-
Chronic sildenafil treatment inhibits monocrotaline-induced pulmonary hypertension in rats
-
Schermuly RT, Kreisselmeier KP, Ghofrani HA et al. Chronic sildenafil treatment inhibits monocrotaline-induced pulmonary hypertension in rats. Am. J. Respir. Crit. Care Med. 169(1), 39-45 (2004 (Pubitemid 38233887)
-
(2004)
American Journal of Respiratory and Critical Care Medicine
, vol.169
, Issue.1
, pp. 39-45
-
-
Schermuly, R.T.1
Kreisselmeier, K.P.2
Ghofrani, H.A.3
Yilmaz, H.4
Butrous, G.5
Ermert, L.6
Ermert, M.7
Weissmann, N.8
Rose, F.9
Guenther, A.10
Walmrath, D.11
Seeger, W.12
Grimminger, F.13
-
66
-
-
0034241419
-
Sildenafil as a selective pulmonary vasodilator in childhood primary pulmonary hypertension
-
Abrams D, Schulze-Neick I, Magee AG. Sildenafil as a selective pulmonary vasodilator in childhood primary pulmonary hypertension. Heart 84(2), E4 (2000
-
(2000)
Heart
, vol.84
, Issue.2
-
-
Abrams, D.1
Schulze-Neick, I.2
Magee, A.G.3
-
67
-
-
0036583457
-
Sildenafil in the management of primary pulmonary hypertension
-
Singh B, Gupta R, Punj V et al. Sildenafil in the management of primary pulmonary hypertension. Indian Heart J. 54(3), 297-300 (2002 (Pubitemid 34987816)
-
(2002)
Indian Heart Journal
, vol.54
, Issue.3
, pp. 297-300
-
-
Singh, B.1
Gupta, R.2
Punj, V.3
Ghose, T.4
Sapra, R.5
Grover, D.N.6
Kaul, U.7
-
68
-
-
0037152092
-
Sildenafil for treatment of lung fibrosis and pulmonary hypertension: A randomised controlled trial
-
DOI 10.1016/S0140-6736(02)11024-5
-
Ghofrani HA, Wiedemann R, Rose F et al. Sildenafil for treatment of lung fibrosis and pulmonary hypertension: a randomised controlled trial. Lancet 360(9337), 895-900 (2002 (Pubitemid 35283832)
-
(2002)
Lancet
, vol.360
, Issue.9337
, pp. 895-900
-
-
Ghofrani, H.A.1
Wiedemann, R.2
Rose, F.3
Schermuly, R.T.4
Olschewski, H.5
Weissmann, N.6
Gunther, A.7
Walmrath, D.8
Seeger, W.9
Grimminger, F.10
-
69
-
-
0037446982
-
Sildenafil for long-term treatment of nonoperable chronic thromboembolic pulmonary hypertension
-
DOI 10.1164/rccm.200210-1157BC
-
Ghofrani HA, Schermuly RT, Rose F et al. Sildenafil for long-term treatment of nonoperable chronic thromboembolic pulmonary hypertension. Am. J. Respir. Crit. Care Med. 167(8), 1139-1141 (2003 (Pubitemid 36459662)
-
(2003)
American Journal of Respiratory and Critical Care Medicine
, vol.167
, Issue.8
, pp. 1139-1141
-
-
Ghofrani, H.A.1
Schermuly, R.T.2
Rose, F.3
Wiedemann, R.4
Kohstall, M.G.5
Kreckel, A.6
Olschewski, H.7
Weissmann, N.8
Enke, B.9
Ghofrani, S.10
Seeger, W.11
Grimminger, F.12
-
70
-
-
1842530387
-
Clinical efficacy of sildenafil in primary pulmonary hypertension: A randomized, placebo-controlled, double-blind, crossover study
-
DOI 10.1016/j.jacc.2003.10.056, PII S0735109704001056
-
Sastry BK, Narasimhan C, Reddy NK, Raju BS. Clinical efficacy of sildenafil in primary pulmonary hypertension: a randomized, placebo-controlled, double-blind, crossover study. J. Am. Coll. Cardiol. 43(7), 1149-1153 (2004 (Pubitemid 38452588)
-
(2004)
Journal of the American College of Cardiology
, vol.43
, Issue.7
, pp. 1149-1153
-
-
Sastry, B.K.S.1
Narasimhan, C.2
Reddy, N.K.3
Raju, B.S.4
-
71
-
-
7244247157
-
Tadalafil in primary pulmonary arterial hypertension [5]
-
Palmieri EA, Affuso F, Fazio S, Lembo D. Tadalafil in primary pulmonary arterial hypertension. Ann. Intern. Med. 141(9), 743-744 (2004 (Pubitemid 39434855)
-
(2004)
Annals of Internal Medicine
, vol.141
, Issue.9
, pp. 743-744
-
-
Palmieri, E.A.1
Affuso, F.2
Fazio, S.3
Lembo, D.4
-
72
-
-
33750553816
-
Phosphodiesterase-5 inhibitor in eisenmenger syndrome: A preliminary observational study
-
DOI 10.1161/CIRCULATIONAHA.105.603001, PII 0000301720061024000006
-
Mukhopadhyay S, Sharma M, Ramakrishnan S et al. Phosphodiesterase-5 inhibitor in Eisenmenger syndrome: a preliminary observational study. Circulation 114(17), 1807-1810 (2006 (Pubitemid 44673355)
-
(2006)
Circulation
, vol.114
, Issue.17
, pp. 1807-1810
-
-
Mukhopadhyay, S.1
Sharma, M.2
Ramakrishnan, S.3
Yusuf, J.4
Gupta, M.D.5
Bhamri, N.6
Trehan, V.7
Tyagi, S.8
-
73
-
-
37749007190
-
Oral tadalafil in pulmonary artery hypertension: A prospective study
-
Aggarwal P, Patial RK, Negi PC, Marwaha R. Oral tadalafil in pulmonary artery hypertension: a prospective study. Indian Heart J. 59(4), 329-335 (2007
-
(2007)
Indian Heart J.
, vol.59
, Issue.4
, pp. 329-335
-
-
Aggarwal, P.1
Patial, R.K.2
Negi, P.C.3
Marwaha, R.4
-
74
-
-
37749036842
-
Efficacy and safety of PDE-5 inhibitor tadalafil in pulmonary arterial hypertension
-
Bharani A, Patel A, Saraf J, Jain A, Mehrotra S, Lunia B. Efficacy and safety of PDE-5 inhibitor tadalafil in pulmonary arterial hypertension. Indian Heart J. 59(4), 323-328 (2007).
-
(2007)
Indian Heart J.
, vol.59
, Issue.4
, pp. 323-328
-
-
Bharani, A.1
Patel, A.2
Saraf, J.3
Jain, A.4
Mehrotra, S.5
Lunia, B.6
-
75
-
-
78650326930
-
Treatment options for paediatric pulmonary arterial hypertension
-
Berger RM, Bonnet D. Treatment options for paediatric pulmonary arterial hypertension. Eur. Respir. Rev. 19(118), 321-330 (2010
-
(2010)
Eur. Respir. Rev.
, vol.19
, Issue.118
, pp. 321-330
-
-
Berger, R.M.1
Bonnet, D.2
-
76
-
-
79953683400
-
Pulmonary arterial hypertension: A comparison between children and adults
-
Barst RJ, Ertel SI, Beghetti M, Ivy DD. Pulmonary arterial hypertension: a comparison between children and adults. Eur. Respir. J. 37(3), 665-677 (2011
-
(2011)
Eur. Respir. J.
, vol.37
, Issue.3
, pp. 665-677
-
-
Barst, R.J.1
Ertel, S.I.2
Beghetti, M.3
Ivy, D.D.4
-
77
-
-
79959766667
-
Tadalafil in geriatric patients with pulmonary arterial hypertension
-
Arneson C, McDevitt S, Klinger JR. Tadalafil in geriatric patients with pulmonary arterial hypertension. Chest 138, 367A (2010
-
(2010)
Chest
, vol.138
-
-
Arneson, C.1
McDevitt, S.2
Klinger, J.R.3
-
78
-
-
52549116511
-
Pulmonary embolism after tadalafil ingestion
-
Chen HC, Wang CS, Chuang SH, Wang CY. Pulmonary embolism after tadalafil ingestion. Pharm. World Sci. 30(5), 610-612 (2008
-
(2008)
Pharm. World Sci.
, vol.30
, Issue.5
, pp. 610-612
-
-
Chen, H.C.1
Wang, C.S.2
Chuang, S.H.3
Wang, C.Y.4
-
79
-
-
0033899475
-
Branch retinal artery occlusion; Another complication of sildenafil
-
Tripathi A, O'Donnell NP. Branch retinal artery occlusion; another complication of sildenafil. Br. J. Ophthalmol. 84(8), 934-935 (2000 (Pubitemid 30599114)
-
(2000)
British Journal of Ophthalmology
, vol.84
, Issue.8
, pp. 934-935
-
-
Tripathi, A.1
O'Donnell, N.P.2
-
80
-
-
23944435538
-
Association of combined nonarteritic anterior ischemic optic neuropathy (NAION) and obstruction of cilioretinal artery with overdose of Viagra®
-
DOI 10.1089/jop.2005.21.315
-
Akash R, Hrishikesh D, Amith P, Sabah S. Case report: association of combined nonarteritic anterior ischemic optic neuropathy (NAION) and obstruction of cilioretinal artery with overdose of Viagra. J. Ocul. Pharmacol. Ther. 21(4), 315-317 (2005 (Pubitemid 41192902)
-
(2005)
Journal of Ocular Pharmacology and Therapeutics
, vol.21
, Issue.4
, pp. 315-317
-
-
Akash, R.1
Hrishikesh, D.2
Amith, P.3
Sabah, S.4
-
81
-
-
21244463854
-
Tadalafil-associated anterior ischaemic optic neuropathy [19]
-
DOI 10.1038/sj.eye.6701614
-
Peter NM, Singh MV, Fox PD. Tadalafil-associated anterior ischaemic optic neuropathy. Eye (Lond.) 19(6), 715-717 (2005 (Pubitemid 40895504)
-
(2005)
Eye
, vol.19
, Issue.6
, pp. 715-717
-
-
Peter, N.M.1
Singh, M.V.2
Fox, P.D.3
-
82
-
-
14944356005
-
Recurrent visual field defect and ischemic optic neuropathy associated with tadalafil rechallenge
-
DOI 10.1001/archopht.123.3.400
-
Bollinger K, Lee MS. Recurrent visual field defect and ischemic optic neuropathy associated with tadalafil rechallenge. Arch. Ophthalmol. 123(3), 400-401 (2005 (Pubitemid 41007591)
-
(2005)
Archives of Ophthalmology
, vol.123
, Issue.3
, pp. 400-401
-
-
Bollinger, K.1
Lee, M.S.2
-
83
-
-
61349114187
-
Sildenafil-and tadalafil-associated optic neuropathy: Implications for men after prostate cancer treatment
-
McKoy JM, Bolden CR, Samaras A, Raisch DW, Chandler K, Bennett CL. Sildenafil-and tadalafil-associated optic neuropathy: implications for men after prostate cancer treatment. Community Oncol. 6(2), 78-80 (2009
-
(2009)
Community Oncol.
, vol.6
, Issue.2
, pp. 78-80
-
-
McKoy, J.M.1
Bolden, C.R.2
Samaras, A.3
Raisch, D.W.4
Chandler, K.5
Bennett, C.L.6
-
84
-
-
58149345209
-
Vision disorders and phosphodiesterase type 5 inhibitors: A review of the evidence to date
-
Laties AM. Vision disorders and phosphodiesterase type 5 inhibitors: a review of the evidence to date. Drug Safety 32(1), 1-18 (2009
-
(2009)
Drug Safety
, vol.32
, Issue.1
, pp. 1-18
-
-
Laties, A.M.1
-
85
-
-
21144437393
-
Sildenafil versus Endothelin Receptor Antagonist for Pulmonary Hypertension (SERAPH) study
-
DOI 10.1164/rccm.200410-1411OC
-
Wilkins MR, Paul GA, Strange JW et al. Sildenafil versus Endothelin Receptor Antagonist for Pulmonary Hypertension (SERAPH) study. Am. J. Respir. Crit. Care Med. 171(11), 1292-1297 (2005 (Pubitemid 40740738)
-
(2005)
American Journal of Respiratory and Critical Care Medicine
, vol.171
, Issue.11
, pp. 1292-1297
-
-
Wilkins, M.R.1
Paul, G.A.2
Strange, J.W.3
Tunariu, N.4
Gin-Sing, W.5
Banya, W.A.6
Westwood, M.A.7
Stefanidis, A.8
Ng, L.L.9
Pennell, D.J.10
Mohiaddin, R.H.11
Nihoyannopoulos, P.12
Gibbs, J.S.R.13
-
86
-
-
79959711799
-
Relationship between dosing and common adverse events with tadalafil in patients with pulmonary arterial hypertension
-
Berman RE, Arneson C, Golden G. Relationship between dosing and common adverse events with tadalafil in patients with pulmonary arterial hypertension. Chest 138, 352A (2010
-
(2010)
Chest
, vol.138
-
-
Berman, R.E.1
Arneson, C.2
Golden, G.3
-
87
-
-
0037006966
-
Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension
-
Ghofrani HA, Wiedemann R, Rose F et al. Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension. Ann. Intern. Med. 136, 515-522 (2002 (Pubitemid 34252285)
-
(2002)
Annals of Internal Medicine
, vol.136
, Issue.7
, pp. 515-522
-
-
Ghofrani, H.A.1
Wiedemann, R.2
Rose, F.3
Olschewski, H.4
Schermuly, R.T.5
Weissmann, N.6
Seeger, W.7
Grimminger, F.8
-
88
-
-
0037868048
-
Oral sildenafil as long-term adjunct therapy to inhaled iloprost in severe pulmonary arterial hypertension
-
DOI 10.1016/S0735-1097(03)00555-2
-
Ghofrani HA, Rose F, Schermuly RT et al. Oral sildenafil as long-term adjunct therapy to inhaled iloprost in severe pulmonary arterial hypertension. J. Am. Coll. Cardiol. 42(1), 158-164 (2003 (Pubitemid 36760778)
-
(2003)
Journal of the American College of Cardiology
, vol.42
, Issue.1
, pp. 158-164
-
-
Ghofrani, H.A.1
Rose, F.2
Schermuly, R.T.3
Olschewski, H.4
Wiedemann, R.5
Kreckel, A.6
Weissmann, N.7
Ghofrani, S.8
Enke, B.9
Seeger, W.10
Grimminger, F.11
-
89
-
-
41849103027
-
Pharmacokinetic interaction between tadalafil and bosentan in healthy male subjects
-
DOI 10.1177/0091270008315315
-
Wrishko RE, Dingemanse J, Yu A, Darstein C, Phillips DL, Mitchell MI. Pharmacokinetic interaction between tadalafil and bosentan in healthy male subjects. J. Clin. Pharmacol. 48(5), 610-618 (2008 (Pubitemid 351503516)
-
(2008)
Journal of Clinical Pharmacology
, vol.48
, Issue.5
, pp. 610-618
-
-
Wrishko, R.E.1
Dingemanse, J.2
Yu, A.3
Darstein, C.4
Phillips, D.L.5
Mitchell, M.I.6
-
90
-
-
70849086064
-
No clinically relevant pharmacokinetic and safety interactions of ambrisentan in combination with tadalafil in healthy volunteers
-
Spence R, Mandagere A, Harrison B, Dufton C, Boinpally R. No clinically relevant pharmacokinetic and safety interactions of ambrisentan in combination with tadalafil in healthy volunteers. J. Pharm. Sci. 98(12), 4962-4974 (2009).
-
(2009)
J. Pharm. Sci.
, vol.98
, Issue.12
, pp. 4962-4974
-
-
Spence, R.1
Mandagere, A.2
Harrison, B.3
Dufton, C.4
Boinpally, R.5
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