메뉴 건너뛰기




Volumn 54, Issue 1 SUPPL. 1, 2009, Pages

Updated Evidence-Based Treatment Algorithm in Pulmonary Arterial Hypertension

Author keywords

algorithm; evidence based treatment; pulmonary arterial hypertension

Indexed keywords

AMBRISENTAN; AMLODIPINE; ANTICOAGULANT AGENT; BERAPROST; BOSENTAN; CALCIUM CHANNEL BLOCKING AGENT; DIGOXIN; DILTIAZEM; DIURETIC AGENT; ILOPROST; NIFEDIPINE; NITRIC OXIDE; PROSTACYCLIN; SILDENAFIL; SITAXSENTAN; TADALAFIL; UNIPROST; WARFARIN;

EID: 67649588196     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2009.04.017     Document Type: Review
Times cited : (458)

References (57)
  • 1
    • 0026632785 scopus 로고
    • The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension
    • Rich S., Kaufmann E., and Levy P.S. The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension. N Engl J Med 327 (1992) 76-81
    • (1992) N Engl J Med , vol.327 , pp. 76-81
    • Rich, S.1    Kaufmann, E.2    Levy, P.S.3
  • 2
    • 0023238042 scopus 로고
    • High-dose calcium channel-blocking therapy for primary pulmonary hypertension: evidence for long-term reduction in pulmonary arterial pressure and regression of right ventricular hypertrophy
    • Rich S., and Brundage B.H. High-dose calcium channel-blocking therapy for primary pulmonary hypertension: evidence for long-term reduction in pulmonary arterial pressure and regression of right ventricular hypertrophy. Circulation 76 (1987) 135-141
    • (1987) Circulation , vol.76 , pp. 135-141
    • Rich, S.1    Brundage, B.H.2
  • 3
    • 0030024879 scopus 로고    scopus 로고
    • Clinical significance of the pulmonary vasodilator response during short-term infusion of prostacyclin in primary pulmonary hypertension
    • Raffy O., Azarian R., Brenot F., et al. Clinical significance of the pulmonary vasodilator response during short-term infusion of prostacyclin in primary pulmonary hypertension. Circulation 93 (1996) 484-488
    • (1996) Circulation , vol.93 , pp. 484-488
    • Raffy, O.1    Azarian, R.2    Brenot, F.3
  • 4
    • 0033537630 scopus 로고    scopus 로고
    • Vasodilator therapy for primary pulmonary hypertension in children
    • Barst R.J., Maislin G., and Fishman A.P. Vasodilator therapy for primary pulmonary hypertension in children. Circulation 99 (1999) 1197-1208
    • (1999) Circulation , vol.99 , pp. 1197-1208
    • Barst, R.J.1    Maislin, G.2    Fishman, A.P.3
  • 5
    • 20544448927 scopus 로고    scopus 로고
    • Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension
    • Sitbon O., Humbert M., Jaïs X., et al. Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension. Circulation 111 (2005) 3105-3111
    • (2005) Circulation , vol.111 , pp. 3105-3111
    • Sitbon, O.1    Humbert, M.2    Jaïs, X.3
  • 7
  • 8
    • 0030813510 scopus 로고    scopus 로고
    • The effect of anticoagulant therapy in primary and anorectic drug-induced pulmonary hypertension
    • Frank H., Mlczoch J., Huber K., Schuster E., Gurtner H.P., and Kneussl M. The effect of anticoagulant therapy in primary and anorectic drug-induced pulmonary hypertension. Chest 112 (1997) 714-721
    • (1997) Chest , vol.112 , pp. 714-721
    • Frank, H.1    Mlczoch, J.2    Huber, K.3    Schuster, E.4    Gurtner, H.P.5    Kneussl, M.6
  • 9
    • 33847388438 scopus 로고    scopus 로고
    • Anticoagulation in pulmonary arterial hypertension: a qualitative systematic review
    • Johnson S.R., Mehta S., and Granton J.T. Anticoagulation in pulmonary arterial hypertension: a qualitative systematic review. Eur Respir J 28 (2006) 999-1004
    • (2006) Eur Respir J , vol.28 , pp. 999-1004
    • Johnson, S.R.1    Mehta, S.2    Granton, J.T.3
  • 10
    • 0025356811 scopus 로고
    • Treatment of primary pulmonary hypertension with continuous intravenous prostacyclin (epoprostenol): results of a randomized trial
    • Rubin L.J., Mendoza J., Hood M., et al. Treatment of primary pulmonary hypertension with continuous intravenous prostacyclin (epoprostenol): results of a randomized trial. Ann Intern Med 112 (1990) 485-491
    • (1990) Ann Intern Med , vol.112 , pp. 485-491
    • Rubin, L.J.1    Mendoza, J.2    Hood, M.3
  • 11
    • 0030031888 scopus 로고    scopus 로고
    • A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension
    • Primary Pulmonary Hypertension Study Group
    • Barst R.J., Rubin L.J., Long W.A., et al., Primary Pulmonary Hypertension Study Group. A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. N Engl J Med 334 (1996) 296-301
    • (1996) N Engl J Med , vol.334 , pp. 296-301
    • Barst, R.J.1    Rubin, L.J.2    Long, W.A.3
  • 12
    • 17144452827 scopus 로고    scopus 로고
    • Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease: a randomized, controlled trial
    • Badesch D.B., Tapson V.F., McGoon M.D., et al. Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease: a randomized, controlled trial. Ann Intern Med 132 (2000) 425-434
    • (2000) Ann Intern Med , vol.132 , pp. 425-434
    • Badesch, D.B.1    Tapson, V.F.2    McGoon, M.D.3
  • 13
    • 0028915973 scopus 로고
    • Blade balloon atrial septostomy in patients with severe primary pulmonary hypertension
    • Kerstein D., Levy P.S., Hsu D.T., Hordof A.J., Gersony W.M., and Barst R.J. Blade balloon atrial septostomy in patients with severe primary pulmonary hypertension. Circulation 91 (1995) 2028-2035
    • (1995) Circulation , vol.91 , pp. 2028-2035
    • Kerstein, D.1    Levy, P.S.2    Hsu, D.T.3    Hordof, A.J.4    Gersony, W.M.5    Barst, R.J.6
  • 14
    • 0034817271 scopus 로고    scopus 로고
    • Atrial septostomy for pulmonary hypertension
    • Sandoval J., Rothman A., and Pulido T. Atrial septostomy for pulmonary hypertension. Clin Chest Med 22 (2001) 547-560
    • (2001) Clin Chest Med , vol.22 , pp. 547-560
    • Sandoval, J.1    Rothman, A.2    Pulido, T.3
  • 15
    • 2942541465 scopus 로고    scopus 로고
    • Interventional and surgical modalities of treatment for pulmonary arterial hypertension
    • Klepetko W., Mayer E., Sandoval J., et al. Interventional and surgical modalities of treatment for pulmonary arterial hypertension. J Am Coll Cardiol 43 (2004) 73S-80S
    • (2004) J Am Coll Cardiol , vol.43
    • Klepetko, W.1    Mayer, E.2    Sandoval, J.3
  • 16
    • 0032145492 scopus 로고    scopus 로고
    • Graded balloon dilation atrial septostomy in severe primary pulmonary hypertension: a therapeutic alternative for patients nonresponsive to vasodilator treatment
    • Sandoval J., Gaspar J., Pulido T., et al. Graded balloon dilation atrial septostomy in severe primary pulmonary hypertension: a therapeutic alternative for patients nonresponsive to vasodilator treatment. J Am Coll Cardiol 32 (1998) 297-304
    • (1998) J Am Coll Cardiol , vol.32 , pp. 297-304
    • Sandoval, J.1    Gaspar, J.2    Pulido, T.3
  • 17
    • 0035818316 scopus 로고    scopus 로고
    • Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study
    • Channick R.N., Simonneau G., Sitbon O., et al. Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study. Lancet 358 (2001) 1119-1123
    • (2001) Lancet , vol.358 , pp. 1119-1123
    • Channick, R.N.1    Simonneau, G.2    Sitbon, O.3
  • 18
    • 20244386797 scopus 로고    scopus 로고
    • Effects of the thromboxane synthetase inhibitor and receptor antagonist terbogrel in patients with primary pulmonary hypertension
    • Langleben D., Christman B.W., Barst R.J., et al. Effects of the thromboxane synthetase inhibitor and receptor antagonist terbogrel in patients with primary pulmonary hypertension. Am Heart J 143 (2002) E4
    • (2002) Am Heart J , vol.143
    • Langleben, D.1    Christman, B.W.2    Barst, R.J.3
  • 19
    • 0037086133 scopus 로고    scopus 로고
    • Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension: a double-blind, randomized, placebo-controlled trial
    • Treprostinil Study Group
    • Simonneau G., Barst R.J., Galiè N., et al., Treprostinil Study Group. Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension: a double-blind, randomized, placebo-controlled trial. Am J Respir Crit Care Med 165 (2002) 800-804
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 800-804
    • Simonneau, G.1    Barst, R.J.2    Galiè, N.3
  • 20
    • 0036569119 scopus 로고    scopus 로고
    • Effects of beraprost sodium, an oral prostacyclin analogue, in patients with pulmonary arterial hypertension: a randomized, double-blind, placebo-controlled trial
    • Arterial Pulmonary Hypertension and Beraprost European Trial (ALPHABET) Study Group
    • Galiè N., Humbert M., Vachiéry J.-L., et al., Arterial Pulmonary Hypertension and Beraprost European Trial (ALPHABET) Study Group. Effects of beraprost sodium, an oral prostacyclin analogue, in patients with pulmonary arterial hypertension: a randomized, double-blind, placebo-controlled trial. J Am Coll Cardiol 39 (2002) 1496-1502
    • (2002) J Am Coll Cardiol , vol.39 , pp. 1496-1502
    • Galiè, N.1    Humbert, M.2    Vachiéry, J.-L.3
  • 21
    • 0036682273 scopus 로고    scopus 로고
    • Inhaled iloprost in severe pulmonary hypertension
    • Aerosolized Iloprost Randomized Study Group
    • Olschewski H., Simonneau G., Galiè N., et al., Aerosolized Iloprost Randomized Study Group. Inhaled iloprost in severe pulmonary hypertension. N Engl J Med 347 (2002) 322-329
    • (2002) N Engl J Med , vol.347 , pp. 322-329
    • Olschewski, H.1    Simonneau, G.2    Galiè, N.3
  • 22
    • 0037149718 scopus 로고    scopus 로고
    • Bosentan therapy for pulmonary arterial hypertension
    • Bosentan Randomized Trial of Endothelin Antagonist Therapy Study Group
    • Rubin L.J., Badesch D.B., Barst R.J., et al., Bosentan Randomized Trial of Endothelin Antagonist Therapy Study Group. Bosentan therapy for pulmonary arterial hypertension. N Engl J Med 346 (2002) 896-903
    • (2002) N Engl J Med , vol.346 , pp. 896-903
    • Rubin, L.J.1    Badesch, D.B.2    Barst, R.J.3
  • 23
    • 0038037766 scopus 로고    scopus 로고
    • Beraprost therapy for pulmonary arterial hypertension
    • Beraprost Study Group
    • Barst R.J., McGoon M., McLaughlin V.V., et al., Beraprost Study Group. Beraprost therapy for pulmonary arterial hypertension. J Am Coll Cardiol 41 (2003) 2119-2125
    • (2003) J Am Coll Cardiol , vol.41 , pp. 2119-2125
    • Barst, R.J.1    McGoon, M.2    McLaughlin, V.V.3
  • 24
    • 1842530387 scopus 로고    scopus 로고
    • Clinical efficacy of sildenafil in primary pulmonary hypertension: a randomized, placebo-controlled, double-blind, crossover study
    • Sastry B.K., Narasimhan C., Reddy N.K., and Raju B.S. Clinical efficacy of sildenafil in primary pulmonary hypertension: a randomized, placebo-controlled, double-blind, crossover study. J Am Coll Cardiol 43 (2004) 1149-1153
    • (2004) J Am Coll Cardiol , vol.43 , pp. 1149-1153
    • Sastry, B.K.1    Narasimhan, C.2    Reddy, N.K.3    Raju, B.S.4
  • 25
    • 10744230817 scopus 로고    scopus 로고
    • Sitaxsentan therapy for pulmonary arterial hypertension
    • STRIDE-1 Study Group
    • Barst R.J., Langleben D., Frost A., et al., STRIDE-1 Study Group. Sitaxsentan therapy for pulmonary arterial hypertension. Am J Respir Crit Care Med 169 (2004) 441-447
    • (2004) Am J Respir Crit Care Med , vol.169 , pp. 441-447
    • Barst, R.J.1    Langleben, D.2    Frost, A.3
  • 26
    • 26444534291 scopus 로고    scopus 로고
    • Sildenafil citrate therapy for pulmonary arterial hypertension
    • Sildenafil Use in Pulmonary Arterial Hypertension (SUPER) Study Group
    • Galiè N., Ghofrani H.A., Torbicki A., et al., Sildenafil Use in Pulmonary Arterial Hypertension (SUPER) Study Group. Sildenafil citrate therapy for pulmonary arterial hypertension. N Engl J Med 353 (2005) 2148-2157
    • (2005) N Engl J Med , vol.353 , pp. 2148-2157
    • Galiè, N.1    Ghofrani, H.A.2    Torbicki, A.3
  • 27
    • 33746206340 scopus 로고    scopus 로고
    • Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study
    • Bosentan Randomized Trial of Endothelin Antagonist Therapy-5 (BREATHE-5) Investigators
    • Galiè N., Beghetti M., Gatzoulis M.A., et al., Bosentan Randomized Trial of Endothelin Antagonist Therapy-5 (BREATHE-5) Investigators. Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study. Circulation 114 (2006) 48-54
    • (2006) Circulation , vol.114 , pp. 48-54
    • Galiè, N.1    Beghetti, M.2    Gatzoulis, M.A.3
  • 28
    • 33646255654 scopus 로고    scopus 로고
    • Treatment of pulmonary arterial hypertension with the selective endothelin-A receptor antagonist sitaxsentan
    • STRIDE-2 Study Group
    • Barst R.J., Langleben D., Badesch D., et al., STRIDE-2 Study Group. Treatment of pulmonary arterial hypertension with the selective endothelin-A receptor antagonist sitaxsentan. J Am Coll Cardiol 47 (2006) 2049-2056
    • (2006) J Am Coll Cardiol , vol.47 , pp. 2049-2056
    • Barst, R.J.1    Langleben, D.2    Badesch, D.3
  • 29
    • 46449124591 scopus 로고    scopus 로고
    • Ambrisentan for the treatment of pulmonary arterial hypertension: results of the Ambrisentan in Pulmonary Arterial Hypertension, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Efficacy (ARIES) Study 1 and 2
    • Ambrisentan in Pulmonary Arterial Hypertension, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Efficacy Studies (ARIES) Group
    • Galiè N., Olschewski H., Oudiz R.J., et al., Ambrisentan in Pulmonary Arterial Hypertension, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Efficacy Studies (ARIES) Group. Ambrisentan for the treatment of pulmonary arterial hypertension: results of the Ambrisentan in Pulmonary Arterial Hypertension, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Efficacy (ARIES) Study 1 and 2. Circulation 117 (2008) 3010-3019
    • (2008) Circulation , vol.117 , pp. 3010-3019
    • Galiè, N.1    Olschewski, H.2    Oudiz, R.J.3
  • 30
    • 45249119855 scopus 로고    scopus 로고
    • Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): a double-blind, randomised controlled trial
    • Galiè N., Rubin L.J., Hoeper M., et al. Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): a double-blind, randomised controlled trial. Lancet 371 (2008) 2093-2100
    • (2008) Lancet , vol.371 , pp. 2093-2100
    • Galiè, N.1    Rubin, L.J.2    Hoeper, M.3
  • 31
    • 67649523052 scopus 로고    scopus 로고
    • Tadalafil therapy for pulmonary arterial hypertension
    • In press
    • Galiè N., Brundage B.H., Ghofrani A., et al. Tadalafil therapy for pulmonary arterial hypertension. Circulation (2009) In press
    • (2009) Circulation
    • Galiè, N.1    Brundage, B.H.2    Ghofrani, A.3
  • 32
    • 4544383466 scopus 로고    scopus 로고
    • Combination of bosentan with epoprostenol in pulmonary arterial hypertension: BREATHE-2
    • Humbert M., Barst R.J., Robbins I.M., et al. Combination of bosentan with epoprostenol in pulmonary arterial hypertension: BREATHE-2. Eur Respir J 24 (2004) 353-359
    • (2004) Eur Respir J , vol.24 , pp. 353-359
    • Humbert, M.1    Barst, R.J.2    Robbins, I.M.3
  • 34
    • 33847368988 scopus 로고    scopus 로고
    • Combining inhaled iloprost with bosentan in patients with idiopathic pulmonary arterial hypertension
    • Hoeper M.M., Leuchte H., Halank M., et al. Combining inhaled iloprost with bosentan in patients with idiopathic pulmonary arterial hypertension. Eur Respir J 28 (2006) 691-694
    • (2006) Eur Respir J , vol.28 , pp. 691-694
    • Hoeper, M.M.1    Leuchte, H.2    Halank, M.3
  • 35
    • 33845526777 scopus 로고    scopus 로고
    • Randomized study of adding inhaled iloprost to existing bosentan in pulmonary arterial hypertension
    • McLaughlin V.V., Oudiz R.J., Frost A., et al. Randomized study of adding inhaled iloprost to existing bosentan in pulmonary arterial hypertension. Am J Respir Crit Care Med 174 (2006) 1257-1263
    • (2006) Am J Respir Crit Care Med , vol.174 , pp. 1257-1263
    • McLaughlin, V.V.1    Oudiz, R.J.2    Frost, A.3
  • 36
    • 53849136180 scopus 로고    scopus 로고
    • TRIUMPH I: efficacy and safety of inhaled treprostinil sodium in patients with pulmonary arterial hypertension (PAH) (abstr)
    • McLaughlin V., Rubin L., Benza R., et al. TRIUMPH I: efficacy and safety of inhaled treprostinil sodium in patients with pulmonary arterial hypertension (PAH) (abstr). Am J Respir Crit Care Med 177 (2008) A965
    • (2008) Am J Respir Crit Care Med , vol.177
    • McLaughlin, V.1    Rubin, L.2    Benza, R.3
  • 37
    • 54549125950 scopus 로고    scopus 로고
    • Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: a randomized trial
    • PACES Study Group
    • Simonneau G., Rubin L.J., Galiè N., et al., PACES Study Group. Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: a randomized trial. Ann Intern Med 149 (2008) 521-530
    • (2008) Ann Intern Med , vol.149 , pp. 521-530
    • Simonneau, G.1    Rubin, L.J.2    Galiè, N.3
  • 38
    • 10044258461 scopus 로고    scopus 로고
    • Guidelines on diagnosis and treatment of pulmonary arterial hypertension. The Task Force on Diagnosis and Treatment of Pulmonary Arterial Hypertension of the European Society of Cardiology
    • Galiè N., Torbicki A., Barst R., et al. Guidelines on diagnosis and treatment of pulmonary arterial hypertension. The Task Force on Diagnosis and Treatment of Pulmonary Arterial Hypertension of the European Society of Cardiology. Eur Heart J 25 (2004) 2243-2278
    • (2004) Eur Heart J , vol.25 , pp. 2243-2278
    • Galiè, N.1    Torbicki, A.2    Barst, R.3
  • 39
    • 62749192201 scopus 로고    scopus 로고
    • A meta-analysis of randomized controlled trials in pulmonary arterial hypertension
    • Galiè N., Manes A., Negro L., et al. A meta-analysis of randomized controlled trials in pulmonary arterial hypertension. Eur Heart J 30 (2009) 394-403
    • (2009) Eur Heart J , vol.30 , pp. 394-403
    • Galiè, N.1    Manes, A.2    Negro, L.3
  • 40
    • 0031719459 scopus 로고    scopus 로고
    • The short-term effects of digoxin in patients with right ventricular dysfunction from pulmonary hypertension
    • Rich S., Seidlitz M., Dodin E., et al. The short-term effects of digoxin in patients with right ventricular dysfunction from pulmonary hypertension. Chest 114 (1998) 787-792
    • (1998) Chest , vol.114 , pp. 787-792
    • Rich, S.1    Seidlitz, M.2    Dodin, E.3
  • 41
    • 64849109410 scopus 로고    scopus 로고
    • ACCF/AHA clinical expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents
    • McLaughlin V.M., Archer S.A., Badesch D.B., et al. ACCF/AHA clinical expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents. J Am Coll Cardiol 53 (2009) 1573-1619
    • (2009) J Am Coll Cardiol , vol.53 , pp. 1573-1619
    • McLaughlin, V.M.1    Archer, S.A.2    Badesch, D.B.3
  • 42
    • 0035508410 scopus 로고    scopus 로고
    • Nocturnal oxygen therapy in patients with the Eisenmenger syndrome
    • Sandoval J., Aguirre J.S., Pulido T., et al. Nocturnal oxygen therapy in patients with the Eisenmenger syndrome. Am J Respir Crit Care Med 164 (2001) 1682-1687
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 1682-1687
    • Sandoval, J.1    Aguirre, J.S.2    Pulido, T.3
  • 43
    • 0022646182 scopus 로고
    • Effect of long term oxygen treatment at home in children with pulmonary vascular disease
    • Bowyer J.J., Busst C.M., Denison D.M., and Shinebourne E.A. Effect of long term oxygen treatment at home in children with pulmonary vascular disease. Br Heart J 55 (1986) 385-390
    • (1986) Br Heart J , vol.55 , pp. 385-390
    • Bowyer, J.J.1    Busst, C.M.2    Denison, D.M.3    Shinebourne, E.A.4
  • 44
    • 67649589485 scopus 로고    scopus 로고
    • Interventional and surgical modalities of treatment in pulmonary hypertension
    • Keogh A., Mayer E., Benza R.L., et al. Interventional and surgical modalities of treatment in pulmonary hypertension. J Am Coll Cardiol 54 Suppl S (2009) S67-S77
    • (2009) J Am Coll Cardiol , vol.54 , Issue.SUPPL. S
    • Keogh, A.1    Mayer, E.2    Benza, R.L.3
  • 45
    • 12244251412 scopus 로고    scopus 로고
    • Efficacy and safety of treprostinil: an epoprostenol analog for primary pulmonary hypertension
    • Treprostinil Study Group
    • McLaughlin V.V., Gaine S.P., Barst R.J., et al., Treprostinil Study Group. Efficacy and safety of treprostinil: an epoprostenol analog for primary pulmonary hypertension. J Cardiovasc Pharmacol 41 (2003) 293-299
    • (2003) J Cardiovasc Pharmacol , vol.41 , pp. 293-299
    • McLaughlin, V.V.1    Gaine, S.P.2    Barst, R.J.3
  • 46
    • 33645119109 scopus 로고    scopus 로고
    • Safety and efficacy of IV treprostinil for pulmonary arterial hypertension: a prospective, multicenter, open-label, 12-week trial
    • Tapson V.F., Gomberg-Maitland M., McLaughlin V.V., et al. Safety and efficacy of IV treprostinil for pulmonary arterial hypertension: a prospective, multicenter, open-label, 12-week trial. Chest 129 (2006) 683-688
    • (2006) Chest , vol.129 , pp. 683-688
    • Tapson, V.F.1    Gomberg-Maitland, M.2    McLaughlin, V.V.3
  • 47
    • 30444458863 scopus 로고    scopus 로고
    • Transition from intravenous epoprostenol to intravenous treprostinil in pulmonary hypertension
    • Gomberg-Maitland M., Tapson V.F., Benza R.L., et al. Transition from intravenous epoprostenol to intravenous treprostinil in pulmonary hypertension. Am J Respir Crit Care Med 172 (2005) 1586-1589
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 1586-1589
    • Gomberg-Maitland, M.1    Tapson, V.F.2    Benza, R.L.3
  • 48
    • 0031920988 scopus 로고    scopus 로고
    • Treatment of pulmonary hypertension with the continuous infusion of a prostacyclin analogue, iloprost
    • Higenbottam T.W., Butt A.Y., Dinh-Xaun A.T., Takao M., Cremona G., and Akamine S. Treatment of pulmonary hypertension with the continuous infusion of a prostacyclin analogue, iloprost. Heart 79 (1998) 175-179
    • (1998) Heart , vol.79 , pp. 175-179
    • Higenbottam, T.W.1    Butt, A.Y.2    Dinh-Xaun, A.T.3    Takao, M.4    Cremona, G.5    Akamine, S.6
  • 49
    • 0344837813 scopus 로고    scopus 로고
    • Effects of the oral endothelin-receptor antagonist bosentan on echocardiographic and Doppler measures in patients with pulmonary arterial hypertension
    • Galiè N., Hinderliter A.L., Torbicki A., et al. Effects of the oral endothelin-receptor antagonist bosentan on echocardiographic and Doppler measures in patients with pulmonary arterial hypertension. J Am Coll Cardiol 41 (2003) 1380-1386
    • (2003) J Am Coll Cardiol , vol.41 , pp. 1380-1386
    • Galiè, N.1    Hinderliter, A.L.2    Torbicki, A.3
  • 50
    • 33846083957 scopus 로고    scopus 로고
    • Sitaxsentan: a selective endothelin-A receptor antagonist, for the treatment of pulmonary arterial hypertension
    • Barst R.J. Sitaxsentan: a selective endothelin-A receptor antagonist, for the treatment of pulmonary arterial hypertension. Expert Opin Pharmacother 8 (2007) 95-109
    • (2007) Expert Opin Pharmacother , vol.8 , pp. 95-109
    • Barst, R.J.1
  • 51
    • 22844436819 scopus 로고    scopus 로고
    • Ambrisentan therapy for pulmonary arterial hypertension
    • Galiè N., Badesch D., Oudiz R., et al. Ambrisentan therapy for pulmonary arterial hypertension. J Am Coll Cardiol 46 (2005) 529-535
    • (2005) J Am Coll Cardiol , vol.46 , pp. 529-535
    • Galiè, N.1    Badesch, D.2    Oudiz, R.3
  • 52
    • 67649878048 scopus 로고    scopus 로고
    • Long-term ambrisentan therapy for pulmonary arterial hypertension in patients who previously received placebo in ARIES-1 or ARIES-2 (abstr)
    • McLaughlin V. Long-term ambrisentan therapy for pulmonary arterial hypertension in patients who previously received placebo in ARIES-1 or ARIES-2 (abstr). Am J Respir Crit Care Med 177 (2008) A697
    • (2008) Am J Respir Crit Care Med , vol.177
    • McLaughlin, V.1
  • 53
    • 38049089932 scopus 로고    scopus 로고
    • Mutual pharmacokinetic interactions between steady-state bosentan and sildenafil
    • Burgess G., Hoogkamer H., Collings L., and Dingemanse J. Mutual pharmacokinetic interactions between steady-state bosentan and sildenafil. Eur J Clin Pharmacol 64 (2008) 43-50
    • (2008) Eur J Clin Pharmacol , vol.64 , pp. 43-50
    • Burgess, G.1    Hoogkamer, H.2    Collings, L.3    Dingemanse, J.4
  • 55
    • 67649867283 scopus 로고    scopus 로고
    • No clinically relevant pharmacokinetic interactions between ambrisentan and tadalafil (abstr)
    • Spence R., Harrison B., Mandagere A., and Dufton C. No clinically relevant pharmacokinetic interactions between ambrisentan and tadalafil (abstr). Chest 134 (2008) 161002
    • (2008) Chest , vol.134 , pp. 161002
    • Spence, R.1    Harrison, B.2    Mandagere, A.3    Dufton, C.4
  • 56
    • 57449121379 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of ambrisentan in combination with sildenafil in healthy volunteers
    • Spence R., Mandagere A., Dufton C., and Venitz J. Pharmacokinetics and safety of ambrisentan in combination with sildenafil in healthy volunteers. J Clin Pharmacol 48 (2008) 1451-1459
    • (2008) J Clin Pharmacol , vol.48 , pp. 1451-1459
    • Spence, R.1    Mandagere, A.2    Dufton, C.3    Venitz, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.