-
1
-
-
0028349156
-
Nitric oxide synthases in mammals
-
Knowles RG, Moncada S: Nitric oxide synthases in mammals. Biochem J 1994; 298:249-58
-
(1994)
Biochem J
, vol.298
, pp. 249-258
-
-
Knowles, R.G.1
Moncada, S.2
-
2
-
-
0025883342
-
Nitric oxide: Physiology, pathophysiology, and pharmacology
-
Moncada S, Palmer RM, Higgs EA: Nitric oxide: Physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991; 43:109-42
-
(1991)
Pharmacol Rev
, vol.43
, pp. 109-142
-
-
Moncada, S.1
Palmer, R.M.2
Higgs, E.A.3
-
3
-
-
0027284439
-
The nitric oxide and cGMP signal transduction system: Regulation and mechanism of action
-
Schmidt HH, Lohmann SM, Walter U: The nitric oxide and cGMP signal transduction system: Regulation and mechanism of action. Biochim Biophys Acta 1993; 1178:153-75
-
(1993)
Biochim Biophys Acta
, vol.1178
, pp. 153-175
-
-
Schmidt, H.H.1
Lohmann, S.M.2
Walter, U.3
-
4
-
-
0027404913
-
Intracellular cyclic GMP receptor proteins
-
Lincoln TM, Cornwell TL: Intracellular cyclic GMP receptor proteins. FASEB J 1993; 7:328-38
-
(1993)
FASEB J
, vol.7
, pp. 328-338
-
-
Lincoln, T.M.1
Cornwell, T.L.2
-
5
-
-
0028802726
-
Cyclic nucleotide phosphodiesterases: Functional implications of multiple isoforms
-
Beavo JA: Cyclic nucleotide phosphodiesterases: Functional implications of multiple isoforms. Physiol Rev 1995; 75:725-48
-
(1995)
Physiol Rev
, vol.75
, pp. 725-748
-
-
Beavo, J.A.1
-
6
-
-
0032546924
-
Identification and characterization of a novel family of cyclic nucleotide phosphodiesterases
-
Soderling SH, Bayuga SJ, Beavo JA: Identification and characterization of a novel family of cyclic nucleotide phosphodiesterases. J Biol Chem 1998; 273:15553-8
-
(1998)
J Biol Chem
, vol.273
, pp. 15553-15558
-
-
Soderling, S.H.1
Bayuga, S.J.2
Beavo, J.A.3
-
7
-
-
0032546779
-
Isolation and characterization of PDE9A, a novel human cGMP-specific phosphodiesterase
-
Fisher D, Smith J, Pillar J, Denis SS, Cheng J: Isolation and characterization of PDE9A, a novel human cGMP-specific phosphodiesterase. J Biol Chem 1998; 273:15559-64
-
(1998)
J Biol Chem
, vol.273
, pp. 15559-15564
-
-
Fisher, D.1
Smith, J.2
Pillar, J.3
Denis, S.S.4
Cheng, J.5
-
8
-
-
0026327575
-
Ca/CaM-stimulated and cGMP-specific phosphodiesterases in vascular and non-vascular tissues
-
Ahn HS, Foster M, Cable M, Pitts BJR, Sybertz EJ: Ca/CaM-stimulated and cGMP-specific phosphodiesterases in vascular and non-vascular tissues. Adv Exp Med Biol 1991; 308:191-7
-
(1991)
Adv Exp Med Biol
, vol.308
, pp. 191-197
-
-
Ahn, H.S.1
Foster, M.2
Cable, M.3
Pitts, B.J.R.4
Sybertz, E.J.5
-
9
-
-
0027406998
-
M&B 22948, a cGMP phosphodiesterase inhibitor, is a pulmonary vasodilator in lambs
-
Braner DA, Fineman JR, Chang R, Soifer SJ: M&B 22948, a cGMP phosphodiesterase inhibitor, is a pulmonary vasodilator in lambs. Am J Physiol 1993; 264:H252-8
-
(1993)
Am J Physiol
, vol.264
-
-
Braner, D.A.1
Fineman, J.R.2
Chang, R.3
Soifer, S.J.4
-
10
-
-
0027167474
-
Influence of zaprinast on vascular tone and vasodilator responses in the cat pulmonary vascular bed
-
McMahon TJ, Ignarro LJ, Kadowitz PJ: Influence of zaprinast on vascular tone and vasodilator responses in the cat pulmonary vascular bed. J Appl Physiol 1993; 74:1704-11
-
(1993)
J Appl Physiol
, vol.74
, pp. 1704-1711
-
-
McMahon, T.J.1
Ignarro, L.J.2
Kadowitz, P.J.3
-
11
-
-
0031758015
-
Effect of DMPPO, a phosphodiesterase type 5 inhibitor, on hypoxic pulmonary hypertension in rats
-
Eddahibi S, Raffestin B, Le Monnier de Gouville AC, Adnot S: Effect of DMPPO, a phosphodiesterase type 5 inhibitor, on hypoxic pulmonary hypertension in rats. Br J Pharmacol 1998; 125:681-8
-
(1998)
Br J Pharmacol
, vol.125
, pp. 681-688
-
-
Eddahibi, S.1
Raffestin, B.2
Le Monnier De Gouville, A.C.3
Adnot, S.4
-
12
-
-
0030070656
-
Inhibition of cyclic 3′-5′-guanosine monophosphate-specific phosphodiesterase selectively vasodilates the pulmonary circulation in chronically hypoxic rats
-
Cohen AH, Hanson K, Morris K, Fouty B, McMurtry IF, Clarke W, Rodman DM: Inhibition of cyclic 3′-5′-guanosine monophosphate-specific phosphodiesterase selectively vasodilates the pulmonary circulation in chronically hypoxic rats. J Clin Invest 1996; 97:172-9
-
(1996)
J Clin Invest
, vol.97
, pp. 172-179
-
-
Cohen, A.H.1
Hanson, K.2
Morris, K.3
Fouty, B.4
McMurtry, I.F.5
Clarke, W.6
Rodman, D.M.7
-
13
-
-
0031979704
-
Dipyridamole potentiates pulmonary vasodilation induced by acetyl-choline and nitric oxide in the ovine fetus
-
Ziegler JW, Ivy DD, Fox JJ, Kinsella JP, Clarke WR, Abman SH: Dipyridamole potentiates pulmonary vasodilation induced by acetyl-choline and nitric oxide in the ovine fetus. Am J Respir Crit Care Med 1998; 157:1104-10
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 1104-1110
-
-
Ziegler, J.W.1
Ivy, D.D.2
Fox, J.J.3
Kinsella, J.P.4
Clarke, W.R.5
Abman, S.H.6
-
14
-
-
0028332080
-
The type III phosphodiesterase inhibitor milrinone and type V PDE inhibitor dipyridamole individually and synergistically reduce elevated pulmonary vascular resistance
-
Clarke WR, Uezono S, Chambers A, Doering EB: The type III phosphodiesterase inhibitor milrinone and type V PDE inhibitor dipyridamole individually and synergistically reduce elevated pulmonary vascular resistance. Pulm Pharmacol 1994; 7:81-9
-
(1994)
Pulm Pharmacol
, vol.7
, pp. 81-89
-
-
Clarke, W.R.1
Uezono, S.2
Chambers, A.3
Doering, E.B.4
-
15
-
-
0030004364
-
Cardiovascular effects of a novel, potent and selective phosphodiesterase 5 inhibitor, DMPPO: In vitro and in vivo characterization
-
Delpy E, Le Monnier de Gouville AC: Cardiovascular effects of a novel, potent and selective phosphodiesterase 5 inhibitor, DMPPO: In vitro and in vivo characterization. Br J Pharmacol 1996: 118:1377-84
-
(1996)
Br J Pharmacol
, vol.118
, pp. 1377-1384
-
-
Delpy, E.1
Le Monnier De Gouville, A.C.2
-
17
-
-
0029096763
-
Dipyridamole, a cGMP phosphodiesterase inhibitor, causes pulmonary vasodilation in the ovine fetus
-
Ziegler JW, Ivy DD, Fox JJ, Kinsella JP, Clarke WR, Abman SH: Dipyridamole, a cGMP phosphodiesterase inhibitor, causes pulmonary vasodilation in the ovine fetus. Am J Physiol 1995; 269:H473-9
-
(1995)
Am J Physiol
, vol.269
-
-
Ziegler, J.W.1
Ivy, D.D.2
Fox, J.J.3
Kinsella, J.P.4
Clarke, W.R.5
Abman, S.H.6
-
18
-
-
0028962935
-
Prolonged pulmonary vasodilator action of inhaled nitric oxide by zaprinast in awake lambs
-
Ichinose F, Adrie C, Hurford WE, Zapol WM: Prolonged pulmonary vasodilator action of inhaled nitric oxide by zaprinast in awake lambs. J Appl Physiol 1995; 78:1288-95
-
(1995)
J Appl Physiol
, vol.78
, pp. 1288-1295
-
-
Ichinose, F.1
Adrie, C.2
Hurford, W.E.3
Zapol, W.M.4
-
19
-
-
0031044878
-
Effective control of refractory pulmonary hypertension after cardiac operations
-
Fullerton DA, Jaggers J, Piedalue F, Grover FL, McIntyre RC Jr: Effective control of refractory pulmonary hypertension after cardiac operations. J Thorac Cardiovasc Surg 1997; 113:363-70
-
(1997)
J Thorac Cardiovasc Surg
, vol.113
, pp. 363-370
-
-
Fullerton, D.A.1
Jaggers, J.2
Piedalue, F.3
Grover, F.L.4
McIntyre R.C., Jr.5
-
20
-
-
0031762610
-
Effects of dipyridamole and inhaled nitric oxide in pediatric patients with pulmonary hypertension
-
Ziegler JW, Ivy DD, Wiggins JW, Kinsella JP, Clarke WR, Abman SH: Effects of dipyridamole and inhaled nitric oxide in pediatric patients with pulmonary hypertension. Am J Respir Crit Care Med 1998; 158:1388-95
-
(1998)
Am J Respir Crit Care Med
, vol.158
, pp. 1388-1395
-
-
Ziegler, J.W.1
Ivy, D.D.2
Wiggins, J.W.3
Kinsella, J.P.4
Clarke, W.R.5
Abman, S.H.6
-
21
-
-
0023653097
-
Dipyridamole
-
Fitzgerald GA: Dipyridamole. N Engl J Med 1987; 316:1247-57
-
(1987)
N Engl J Med
, vol.316
, pp. 1247-1257
-
-
Fitzgerald, G.A.1
-
22
-
-
0022637702
-
Mechanisms of the antiplatelet action of dipyridamole in whole blood: Modulation of adenosine concentration and activity
-
Gresele P, Arnout J, Deckmyn H, Vermylen J: Mechanisms of the antiplatelet action of dipyridamole in whole blood: Modulation of adenosine concentration and activity. Thromb Haemost 1986; 55:12-8
-
(1986)
Thromb Haemost
, vol.55
, pp. 12-18
-
-
Gresele, P.1
Arnout, J.2
Deckmyn, H.3
Vermylen, J.4
-
23
-
-
0030438222
-
Sildenafil, a novel effective oral therapy for male erectile dysfunction
-
Boolell M, Gepi-Attee S, Gingell JC, Allen MJ: Sildenafil, a novel effective oral therapy for male erectile dysfunction. Br J Urol 1996; 78:257-61
-
(1996)
Br J Urol
, vol.78
, pp. 257-261
-
-
Boolell, M.1
Gepi-Attee, S.2
Gingell, J.C.3
Allen, M.J.4
-
24
-
-
0030154874
-
Sildenafil: An orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction
-
Boolell M, Allen MJ, Ballard SA, Gepi-Attee S, Muirhead GJ, Naylor AM, Osterloh IH, Gingell C: Sildenafil: An orally active type 5 cyclic GMP-specific phosphodiesterase Inhibitor for the treatment of penile erectile dysfunction. Int J Impot Res 1996; 8:47-52
-
(1996)
Int J Impot Res
, vol.8
, pp. 47-52
-
-
Boolell, M.1
Allen, M.J.2
Ballard, S.A.3
Gepi-Attee, S.4
Muirhead, G.J.5
Naylor, A.M.6
Osterloh, I.H.7
Gingell, C.8
-
25
-
-
0033547738
-
Use of sildenafil (Viagra) in patients with cardiovascular disease
-
Cheitlin MD, Hutter AM, Brindis RG, Ganz P, Kaul S, Russell RO, Zusman RM: Use of sildenafil (Viagra) in patients with cardiovascular disease. Circulation 1999; 99:168-77
-
(1999)
Circulation
, vol.99
, pp. 168-177
-
-
Cheitlin, M.D.1
Hutter, A.M.2
Brindis, R.G.3
Ganz, P.4
Kaul, S.5
Russell, R.O.6
Zusman, R.M.7
-
27
-
-
0025979247
-
Hemodynamic profiles of prostaglandin El, isoproterenol, prostacyclin, and nifedipine in experimental porcine pulmonary hypertension
-
Prielipp RC, McLean R, Rosenthal MH, Pearl RG: Hemodynamic profiles of prostaglandin El, isoproterenol, prostacyclin, and nifedipine in experimental porcine pulmonary hypertension. Crit Care Med 1991; 19:60-7
-
(1991)
Crit Care Med
, vol.19
, pp. 60-67
-
-
Prielipp, R.C.1
McLean, R.2
Rosenthal, M.H.3
Pearl, R.G.4
-
28
-
-
0030780668
-
Development of an assay for the simultaneous determination of sildenafil (Viagra) and its metabolite (UK-103,320) using automated sequential trace enrichment of dialysates and high-performance liquid chromatography
-
Cooper JD, Muirhead DC, Taylor JE, Baker PR: Development of an assay for the simultaneous determination of sildenafil (Viagra) and its metabolite (UK-103,320) using automated sequential trace enrichment of dialysates and high-performance liquid chromatography. J Chromatogr B 1997; 701:87-95
-
(1997)
J Chromatogr B
, vol.701
, pp. 87-95
-
-
Cooper, J.D.1
Muirhead, D.C.2
Taylor, J.E.3
Baker, P.R.4
-
29
-
-
0028011050
-
Effects of inhaled nitric oxide on pulmonary hemodynamics and gas exchange in an ovine model of ARDS
-
Rovira I, Chen TY, Winkler M, Kawai N, Bloch KD, Zapol WM: Effects of inhaled nitric oxide on pulmonary hemodynamics and gas exchange in an ovine model of ARDS. J Appl Physiol 1994; 76:345-55
-
(1994)
J Appl Physiol
, vol.76
, pp. 345-355
-
-
Rovira, I.1
Chen, T.Y.2
Winkler, M.3
Kawai, N.4
Bloch, K.D.5
Zapol, W.M.6
-
30
-
-
0028074792
-
Cyclic nucleotide phosphodiesterases in the human lung
-
Dent G, Magnussen H, Rabe KF: Cyclic nucleotide phosphodiesterases in the human lung. Lung 1994; 172:129-46
-
(1994)
Lung
, vol.172
, pp. 129-146
-
-
Dent, G.1
Magnussen, H.2
Rabe, K.F.3
-
31
-
-
0032516296
-
Oral sildenafil in the treatment of erectile dysfunction
-
Goldstein I, Lue TF, Padma-Nathan H, Rosen RC, Steers WD, Wicker PA: Oral sildenafil in the treatment of erectile dysfunction. N Engl J Med 1998; 338:1397-404
-
(1998)
N Engl J Med
, vol.338
, pp. 1397-1404
-
-
Goldstein, I.1
Lue, T.F.2
Padma-Nathan, H.3
Rosen, R.C.4
Steers, W.D.5
Wicker, P.A.6
-
34
-
-
0032445219
-
Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and the activities of cyclic nucleotide phosphodiesterase isozymes
-
Ballard SA, Gingell JC, Tang K, Turner LA, Price ME, Naylor AM: Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and the activities of cyclic nucleotide phosphodiesterase isozymes. J Urol 1998; 159:2164-71
-
(1998)
J Urol
, vol.159
, pp. 2164-2171
-
-
Ballard, S.A.1
Gingell, J.C.2
Tang, K.3
Turner, L.A.4
Price, M.E.5
Naylor, A.M.6
-
35
-
-
0031818659
-
Endogenous neurotransmitters mediating penile errection
-
Naylor AM: Endogenous neurotransmitters mediating penile errection. Br J Urol 1998; 81:424-31
-
(1998)
Br J Urol
, vol.81
, pp. 424-431
-
-
Naylor, A.M.1
-
36
-
-
0026353632
-
Nitric oxide as a mediator of relaxation of the corpus cavernosum in response to nonadrenergic, noncholinergic neurotransmission
-
Rajfer J, Aronson WJ, Bush PA, Dorey FJ, Ignarro LJ: Nitric oxide as a mediator of relaxation of the corpus cavernosum in response to nonadrenergic, noncholinergic neurotransmission. N Engl J Med 1992; 326:90-4
-
(1992)
N Engl J Med
, vol.326
, pp. 90-94
-
-
Rajfer, J.1
Aronson, W.J.2
Bush, P.A.3
Dorey, F.J.4
Ignarro, L.J.5
-
37
-
-
0024316058
-
Atrial natriuretic factor-induced egression of cyclic guanosine 3′:5′-monophosphate in cultured vascular smooth muscle and endothelial cells
-
Hamet P, Pang SC, Tremblay J: Atrial natriuretic factor-induced egression of cyclic guanosine 3′:5′-monophosphate in cultured vascular smooth muscle and endothelial cells. J Biol Chem 1989; 264: 12364-9
-
(1989)
J Biol Chem
, vol.264
, pp. 12364-12369
-
-
Hamet, P.1
Pang, S.C.2
Tremblay, J.3
-
38
-
-
0024426035
-
Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium derived relaxing factor
-
Archer SL, Tolins JP, Raij L, Weir EK: Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium derived relaxing factor. Biochem Biophys Res Commun 1989; 164:1198-205
-
(1989)
Biochem Biophys Res Commun
, vol.164
, pp. 1198-1205
-
-
Archer, S.L.1
Tolins, J.P.2
Raij, L.3
Weir, E.K.4
-
39
-
-
0024263973
-
Augmentation of hypoxic pulmonary vasoconstriction in the isolated perfused rat lung by in vitro antagonists of endothelium-dependent relaxation
-
Brashers VL, Peach MJ, Rose CE Jr: Augmentation of hypoxic pulmonary vasoconstriction in the isolated perfused rat lung by in vitro antagonists of endothelium-dependent relaxation. J Clin Invest 1988; 82:1495-502
-
(1988)
J Clin Invest
, vol.82
, pp. 1495-1502
-
-
Brashers, V.L.1
Peach, M.J.2
Rose C.E., Jr.3
-
40
-
-
0025977583
-
Endothelium-derived relaxing factor inhibits hypoxlc pulmonary vasoconstriction in rats
-
Liu S, Crawley DE, Barnes PJ, Evans TW: Endothelium-derived relaxing factor inhibits hypoxlc pulmonary vasoconstriction in rats.Am Rev Respir Dis 1991; 143:32-7
-
(1991)
Am Rev Respir Dis
, vol.143
, pp. 32-37
-
-
Liu, S.1
Crawley, D.E.2
Barnes, P.J.3
Evans, T.W.4
-
41
-
-
0031891223
-
Selective pulmonary vasodilation induced by aerosolized zaprinast
-
Ichinose F, Adrie C, Hurford WE, Bloch KD, Zapol WM: Selective pulmonary vasodilation induced by aerosolized zaprinast. ANESTHESIOLOGY 1998; 88:410-6
-
(1998)
Anesthesiology
, vol.88
, pp. 410-416
-
-
Ichinose, F.1
Adrie, C.2
Hurford, W.E.3
Bloch, K.D.4
Zapol, W.M.5
-
42
-
-
0344157338
-
Selective pulmonary vasodilation by intravenous infusion of an ultrashort half-life nucleophile/nitric oxide adduct
-
Adrie C, Hirani WM, Holzmann A, Keefer L, Zapol WM, Hurford WE: Selective pulmonary vasodilation by intravenous infusion of an ultrashort half-life nucleophile/nitric oxide adduct. ANESTHESIOLOGY 1998; 88:190-5
-
(1998)
Anesthesiology
, vol.88
, pp. 190-195
-
-
Adrie, C.1
Hirani, W.M.2
Holzmann, A.3
Keefer, L.4
Zapol, W.M.5
Hurford, W.E.6
-
43
-
-
0026346162
-
Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock
-
Petros A, Bennett D, Vallance P: Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock. Lancet 1991; 338:1557-8
-
(1991)
Lancet
, vol.338
, pp. 1557-1558
-
-
Petros, A.1
Bennett, D.2
Vallance, P.3
-
44
-
-
0031975630
-
Effects of inhaled nitric oxide in patients with acute respiratory distress syndrome: Results of a randomized phase II trial
-
Dellinger RP, Zimmerman JL, Taylor RW, Straube RC, Hauser DL, Criner GJ, Davis KJ, Hyers TM, Papadakos P: Effects of inhaled nitric oxide in patients with acute respiratory distress syndrome: Results of a randomized phase II trial. Crit Care Med 1998; 26:15-23
-
(1998)
Crit Care Med
, vol.26
, pp. 15-23
-
-
Dellinger, R.P.1
Zimmerman, J.L.2
Taylor, R.W.3
Straube, R.C.4
Hauser, D.L.5
Criner, G.J.6
Davis, K.J.7
Hyers, T.M.8
Papadakos, P.9
-
45
-
-
0013655172
-
Inhaled nitric oxide and persistent pulmonary hypertension of the newborn
-
Roberts JD Jr, Fineman JR, Morin FC 3, Shaul PW, Rimar S, Schreiber MD, Polin RA, Zwass MS, Zayek MM, Gross I, Heymann MA, Zapol WM: Inhaled nitric oxide and persistent pulmonary hypertension of the newborn. N Engl J Med 1997; 336:605-10
-
(1997)
N Engl J Med
, vol.336
, pp. 605-610
-
-
Roberts J.D., Jr.1
Fineman, J.R.2
Morin F.C. III3
Shaul, P.W.4
Rimar, S.5
Schreiber, M.D.6
Polin, R.A.7
Zwass, M.S.8
Zayek, M.M.9
Gross, I.10
Heymann, M.A.11
Zapol, W.M.12
-
46
-
-
0027389250
-
Inhaled nitric oxide for the adult respiratory distress syndrome
-
Rossaint R, Falke KJ, Lopez F, Slama K, Pison U, Zapol WM: Inhaled nitric oxide for the adult respiratory distress syndrome. N Engl J Med 1993; 328:399-405
-
(1993)
N Engl J Med
, vol.328
, pp. 399-405
-
-
Rossaint, R.1
Falke, K.J.2
Lopez, F.3
Slama, K.4
Pison, U.5
Zapol, W.M.6
-
47
-
-
0030064790
-
Isolation and characterization of cDNAs corresponding to two human calcium, calmodulin-regulated, 3′,5′-cyclic nucleotide phosphodiesterases
-
Loughney K, Martins J, Harris EA, Sadhu K, Hicks JB, Sonnenburg WK, Beavo JA: Isolation and characterization of cDNAs corresponding to two human calcium, calmodulin-regulated, 3′,5′-cyclic nucleotide phosphodiesterases. J Biol Chem 1996; 271:796-806
-
(1996)
J Biol Chem
, vol.271
, pp. 796-806
-
-
Loughney, K.1
Martins, J.2
Harris, E.A.3
Sadhu, K.4
Hicks, J.B.5
Sonnenburg, W.K.6
Beavo, J.A.7
|