-
1
-
-
0029062054
-
Theophylline and selective phosphodiesterase inhibitors as antiinflammatory drugs in the treatment of bronchial asthma
-
BANNER, K. H. AND PAGE, C. P.: Theophylline and selective phosphodiesterase inhibitors as antiinflammatory drugs in the treatment of bronchial asthma. Eur. Resp. J. 66: 996-1000, 1995.
-
(1995)
Eur. Resp. J.
, vol.66
, pp. 996-1000
-
-
Banner, K.H.1
Page, C.P.2
-
2
-
-
0028802726
-
Cyclic nucleotide phosphodiesterases - Functional implications of multiple isoforms
-
BEAVO J. A.: Cyclic nucleotide phosphodiesterases - functional implications of multiple isoforms. Physiol. Rev. 75: 725-748, 1995.
-
(1995)
Physiol. Rev.
, vol.75
, pp. 725-748
-
-
Beavo, J.A.1
-
3
-
-
0026844552
-
Regulation and function of cyclic nucleotides
-
BENTLEY, J. K. AND BEAVO, J. A.: Regulation and function of cyclic nucleotides. Curr. Opin. Cell Biol. 4: 233-240, 1992.
-
(1992)
Curr. Opin. Cell Biol.
, vol.4
, pp. 233-240
-
-
Bentley, J.K.1
Beavo, J.A.2
-
4
-
-
0028574848
-
Molecular biology of the cyclic AMP-specific cyclic nucleotide phosphodiesterases: A diverse family of regulatory enzymes
-
BOLGER, G.: Molecular biology of the cyclic AMP-specific cyclic nucleotide phosphodiesterases: A diverse family of regulatory enzymes. Cellular Signalling 6: 851-859, 1994.
-
(1994)
Cellular Signalling
, vol.6
, pp. 851-859
-
-
Bolger, G.1
-
5
-
-
0027406998
-
M&B 22948, a cGMP phosphodiesterase inhibitor, is a pulmonary vasodilator in lambs
-
BRANER, D. A., FINEMAN, J. R., CHANG, R. AND SOIFER, S. J.: M&B 22948, a cGMP phosphodiesterase inhibitor, is a pulmonary vasodilator in lambs. Am. J. Physiol. 264: H252-H258, 1993.
-
(1993)
Am. J. Physiol.
, vol.264
-
-
Braner, D.A.1
Fineman, J.R.2
Chang, R.3
Soifer, S.J.4
-
6
-
-
77956840791
-
Isozyme-selective phosphodiesterase inhibitors as antiasthmatic agents
-
CHRISTENSEN, S. B. AND TORPHY, T. J.: Isozyme-selective phosphodiesterase inhibitors as antiasthmatic agents. Ann. Rep. Med. Chem. 29: 185-194, 1994.
-
(1994)
Ann. Rep. Med. Chem.
, vol.29
, pp. 185-194
-
-
Christensen, S.B.1
Torphy, T.J.2
-
7
-
-
0028332080
-
The type-III phosphodiesterase inhibitor milrinone and type-V PDE inhibitor dipyridamole individually and synergistically reduce elevated pulmonary vascular resistance
-
CLARKE, W. R., UEZONA, S., VILLACRES, E. C. AND STORM, D. R.: The type-III phosphodiesterase inhibitor milrinone and type-V PDE inhibitor dipyridamole individually and synergistically reduce elevated pulmonary vascular resistance. Pulm. Pharmacol. 7: 81-89, 1994.
-
(1994)
Pulm. Pharmacol.
, vol.7
, pp. 81-89
-
-
Clarke, W.R.1
Uezona, S.2
Villacres, E.C.3
Storm, D.R.4
-
8
-
-
0027535918
-
Investigation into the role of phosphodiesterase IV in bronchorelaxation, including studies with human bronchus
-
CORTIJO, J., Bou, J., BELETA, J., CARDEL'US, I., LLENAS, J., MORCILLO, E. AND GRISTWOOD, R. W.: Investigation into the role of phosphodiesterase IV in bronchorelaxation, including studies with human bronchus. Br. J. Pharmacol. 108: 562-568, 1993.
-
(1993)
Br. J. Pharmacol.
, vol.108
, pp. 562-568
-
-
Cortijo, J.1
Bou, J.2
Beleta, J.3
Cardel'us, I.4
Llenas, J.5
Morcillo, E.6
Gristwood, R.W.7
-
9
-
-
0028153381
-
Effect of inhibitors of nitric oxide release and action on vascular tone in isolated lungs of pig, sheep, dog and man
-
CREMONA, G., WOOD, A. M., HALL, L. W., BOWER, E. A. AND HIGENBOTTAM, T.: Effect of inhibitors of nitric oxide release and action on vascular tone in isolated lungs of pig, sheep, dog and man. J. Physiol. 481: 185-195, 1994.
-
(1994)
J. Physiol.
, vol.481
, pp. 185-195
-
-
Cremona, G.1
Wood, A.M.2
Hall, L.W.3
Bower, E.A.4
Higenbottam, T.5
-
10
-
-
0031028090
-
Challenge of human Jurkat T-cells with the adenylate cyclase activator forskolin elicits major changes in cAMP phosphodiesterase (PDE) expression by up-regulating and inducing PDE4D1 and PDE4D2 splice variants as well as down-regulating a novel PDE4A splice variant
-
ERDOGAN, S. AND HOUSLAY, M. D.: Challenge of human Jurkat T-cells with the adenylate cyclase activator forskolin elicits major changes in cAMP phosphodiesterase (PDE) expression by up-regulating and inducing PDE4D1 and PDE4D2 splice variants as well as down-regulating a novel PDE4A splice variant. Biochem. J. 321: 165-175, 1997.
-
(1997)
Biochem. J.
, vol.321
, pp. 165-175
-
-
Erdogan, S.1
Houslay, M.D.2
-
11
-
-
0027980209
-
Guanylyl cyclases - A family of receptor-linked enzymes
-
FULLE, H. J. AND GARBERS, D. L.: Guanylyl cyclases - a family of receptor-linked enzymes. Cell Biochem. Function 12: 157-165, 1994.
-
(1994)
Cell Biochem. Function
, vol.12
, pp. 157-165
-
-
Fulle, H.J.1
Garbers, D.L.2
-
12
-
-
0029055964
-
Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension
-
GIAID, A. AND SALEH, D.: Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension. New Eng. J. Med. 333: 214-221, 1995.
-
(1995)
New Eng. J. Med.
, vol.333
, pp. 214-221
-
-
Giaid, A.1
Saleh, D.2
-
13
-
-
0030248274
-
Phosphodiesterase 4 and tolerance to beta (2)-adrenoceptor agonists in asthma
-
GIEMBYCZ, M. A.: Phosphodiesterase 4 and tolerance to beta (2)-adrenoceptor agonists in asthma. Trends Pharmacol. Sci. 17: 331-336, 1996.
-
(1996)
Trends Pharmacol. Sci.
, vol.17
, pp. 331-336
-
-
Giembycz, M.A.1
-
14
-
-
0024306482
-
Inhibition and stimulation of photoreceptor phosphodiesterases by dipyridamole and M&B 22948
-
GILLESPIE, P. G. AND BEAVO, J. A.: Inhibition and stimulation of photoreceptor phosphodiesterases by dipyridamole and M&B 22948. Mol. Pharmacol. 36: 773-781, 1989.
-
(1989)
Mol. Pharmacol.
, vol.36
, pp. 773-781
-
-
Gillespie, P.G.1
Beavo, J.A.2
-
15
-
-
0015547186
-
Effects on the right ventricle, pulmonary vasculature, and carotid bodies of the rat of exposure to, and recovery from, simulated high altitude
-
HEATH, C., EDWARDS, M., WINSON, M AND SMITH, P.: Effects on the right ventricle, pulmonary vasculature, and carotid bodies of the rat of exposure to, and recovery from, simulated high altitude. Thorax 28: 24-28, 1973.
-
(1973)
Thorax
, vol.28
, pp. 24-28
-
-
Heath, C.1
Edwards, M.2
Winson, M.3
Smith, P.4
-
16
-
-
0018103315
-
Resolution of pulmonary hypertension and other features induced by chronic hypoxia in rats during complete and intermittent normoxia
-
HERGET, J., SUGGETT, A. J., LEACH, E. AND BARER, G. R.: Resolution of pulmonary hypertension and other features induced by chronic hypoxia in rats during complete and intermittent normoxia. Thorax 33: 468-473, 1978.
-
(1978)
Thorax
, vol.33
, pp. 468-473
-
-
Herget, J.1
Suggett, A.J.2
Leach, E.3
Barer, G.R.4
-
17
-
-
0028962935
-
Prolonged pulmonary vasodilator action of inhaled nitric oxide by zaprinast in awake lambs
-
ICHINOSE, F., ADRIE, C., HURFORD, W. E. AND ZAPOL, W. R.: Prolonged pulmonary vasodilator action of inhaled nitric oxide by zaprinast in awake lambs. J. Appl. Physiol. 78: 1288-1295, 1995.
-
(1995)
J. Appl. Physiol.
, vol.78
, pp. 1288-1295
-
-
Ichinose, F.1
Adrie, C.2
Hurford, W.E.3
Zapol, W.R.4
-
18
-
-
0028211799
-
Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats
-
ISAACSON, T. C., HAMPL, V., WEIR, E. K., NELSON, D. P. AND ARCHER, S. L.: Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats. J. Appl. Physiol. 76: 933-940, 1994.
-
(1994)
J. Appl. Physiol.
, vol.76
, pp. 933-940
-
-
Isaacson, T.C.1
Hampl, V.2
Weir, E.K.3
Nelson, D.P.4
Archer, S.L.5
-
19
-
-
0029925701
-
Targeting signal transduction for disease therapy
-
LEVITZKI, A.: Targeting signal transduction for disease therapy. Curr. Opin. Cell Biol. 8: 239-244, 1996.
-
(1996)
Curr. Opin. Cell Biol.
, vol.8
, pp. 239-244
-
-
Levitzki, A.1
-
22
-
-
0028844602
-
Effects of pulmonary hypertension on vasoconstrictor responses to endothelin-1 and sarafotoxin S6C and on inherent tone in rat pulmonary arteries
-
MACLEAN, M. R., MCCULLOCH, K. M. AND BAIRD, M.: Effects of pulmonary hypertension on vasoconstrictor responses to endothelin-1 and sarafotoxin S6C and on inherent tone in rat pulmonary arteries. J. Cardiovasc. Pharmacol. 26: 822-830, 1995.
-
(1995)
J. Cardiovasc. Pharmacol.
, vol.26
, pp. 822-830
-
-
Maclean, M.R.1
Mcculloch, K.M.2
Baird, M.3
-
23
-
-
0029911551
-
5-Hydroxytryptamine receptors mediating vasoconstriction in pulmonary arteries from control and pulmonary hypertensive rats
-
MACLEAN, M. R., SWEENEY, G., BAIRD, M., MCCULLOCH, K. M., HOUSLAY, M. AND MORECROFT, I.: 5-Hydroxytryptamine receptors mediating vasoconstriction in pulmonary arteries from control and pulmonary hypertensive rats. Br. J. Pharmacol. 119: 917-930, 1996.
-
(1996)
Br. J. Pharmacol.
, vol.119
, pp. 917-930
-
-
Maclean, M.R.1
Sweeney, G.2
Baird, M.3
Mcculloch, K.M.4
Houslay, M.5
Morecroft, I.6
-
24
-
-
0029146718
-
Diversity in cyclic nucleotide phosphodiesterase isoenzyme families
-
MANGANIELLO, V. C., MURATA, T., TAIRA, M., BELFRAGE, P. AND DEGERMAN, E.: Diversity in cyclic nucleotide phosphodiesterase isoenzyme families. Arch. Biochem. Biophy. 322: 1-13, 1995a.
-
(1995)
Arch. Biochem. Biophy.
, vol.322
, pp. 1-13
-
-
Manganiello, V.C.1
Murata, T.2
Taira, M.3
Belfrage, P.4
Degerman, E.5
-
25
-
-
0029075805
-
Type III cGMP-inhibited cyclic nucleotide phosphodiesterases (PDE3 gene family)
-
MANGANIELLO, V. C., TAIRA, M., DEGERMAN, E. AND BELFRAGE, P.: Type III cGMP-inhibited cyclic nucleotide phosphodiesterases (PDE3 gene family). Cell. Sig. 7: 445-455, 1995b.
-
(1995)
Cell. Sig.
, vol.7
, pp. 445-455
-
-
Manganiello, V.C.1
Taira, M.2
Degerman, E.3
Belfrage, P.4
-
26
-
-
0028231431
-
HIV and pulmonary hypertension - A review
-
MANI, S. AND SMITH, G. J. W.: HIV and pulmonary hypertension - a review. Southern Med. J. 87: 357-362, 1994.
-
(1994)
Southern Med. J.
, vol.87
, pp. 357-362
-
-
Mani, S.1
Smith, G.J.W.2
-
27
-
-
0019015257
-
A peripheral and an intrinsic enzyme constitute the cyclic AMP phosphodiesterase activity of rat liver plasma membranes
-
MARCHMONT, R. J. AND HOUSLAY, M. D.: A peripheral and an intrinsic enzyme constitute the cyclic AMP phosphodiesterase activity of rat liver plasma membranes. Biochem. J. 187: 381-392, 1980.
-
(1980)
Biochem. J.
, vol.187
, pp. 381-392
-
-
Marchmont, R.J.1
Houslay, M.D.2
-
28
-
-
0029962380
-
Rapid regulation of PDE-2 and PDE-4 cyclic AMP phosphodiesterase activity following ligation of the T-cell antigen receptor on thymocytes - Analysis using the selective inhibitors erythro-9-(2-hydroxy-3-nonyl)-adenine (EHNA) and rolipram
-
MICHIE, A. M., LOBBAN, M., HARNETT, M. M. AND HOUSLAY, M. D.: Rapid regulation of PDE-2 and PDE-4 cyclic AMP phosphodiesterase activity following ligation of the T-cell antigen receptor on thymocytes - analysis using the selective inhibitors erythro-9-(2-hydroxy-3-nonyl)-adenine (EHNA) and rolipram. Cell. Sig. 8: 97-110, 1996.
-
(1996)
Cell. Sig.
, vol.8
, pp. 97-110
-
-
Michie, A.M.1
Lobban, M.2
Harnett, M.M.3
Houslay, M.D.4
-
29
-
-
0029088562
-
Isozyme-selective inhibition of cGMP-stimulated cyclic-nucleotide phosphodiesterases by erythro-9-(2-hydroxy-3-nonyl) adenine
-
PODZUWEIT, T., NENNSTIEL, P. AND MULLER, A.: Isozyme-selective inhibition of cGMP-stimulated cyclic-nucleotide phosphodiesterases by erythro-9-(2-hydroxy-3-nonyl) adenine. Cell. Sig. 7: 733-738, 1995.
-
(1995)
Cell. Sig.
, vol.7
, pp. 733-738
-
-
Podzuweit, T.1
Nennstiel, P.2
Muller, A.3
-
30
-
-
0029942933
-
Cyclic nucleotide phosphodiesterases and vascular smooth muscle
-
POLSON, J. B. AND STRADA, S. J.: Cyclic nucleotide phosphodiesterases and vascular smooth muscle. Ann. Rev. Pharmacol. Toxicol. 36: 403-427, 1996.
-
(1996)
Ann. Rev. Pharmacol. Toxicol.
, vol.36
, pp. 403-427
-
-
Polson, J.B.1
Strada, S.J.2
-
31
-
-
0028365921
-
Identification of PDE isozymes in human pulmonary artery and effect of selective PDE inhibitors
-
RABE, K. F., TENOR, H., DENT, G., SCHUDT, C., NAKASHIMA, M. AND MAGNUSSEN, H.: Identification of PDE isozymes in human pulmonary artery and effect of selective PDE inhibitors. Am. J. Physiol. 266: L536-L543, 1994.
-
(1994)
Am. J. Physiol.
, vol.266
-
-
Rabe, K.F.1
Tenor, H.2
Dent, G.3
Schudt, C.4
Nakashima, M.5
Magnussen, H.6
-
32
-
-
0025228573
-
Effects of hypoxia on endothelium-dependent relaxation of rat pulmonary artery
-
RODMAN, D. M., YAMAGUCHI, T., HASUNUMA, K., O'BRIEN, R. F. AND MCMURTRY, I. F.: Effects of hypoxia on endothelium-dependent relaxation of rat pulmonary artery. Am. J. Physiol. 250: L207-214, 1990.
-
(1990)
Am. J. Physiol.
, vol.250
-
-
Rodman, D.M.1
Yamaguchi, T.2
Hasunuma, K.3
O'Brien, R.F.4
Mcmurtry, I.F.5
-
33
-
-
0029013020
-
Structural organization of pulmonary arteries in the rat lung
-
SASAKI, S. I., KOBAYASHI, N., DAMBARA, T., KIRA, S. AND SAKAI, T.: Structural organization of pulmonary arteries in the rat lung. Anat. Embryol. 191: 477-489, 1995.
-
(1995)
Anat. Embryol.
, vol.191
, pp. 477-489
-
-
Sasaki, S.I.1
Kobayashi, N.2
Dambara, T.3
Kira, S.4
Sakai, T.5
-
34
-
-
0025810398
-
Cyclic nucleotide-dependent protein kinases
-
SCOTT, J. D.: Cyclic nucleotide-dependent protein kinases. Pharmacol. Ther. 50: 123-145, 1991.
-
(1991)
Pharmacol. Ther.
, vol.50
, pp. 123-145
-
-
Scott, J.D.1
-
35
-
-
0027370627
-
Acute and prolonged hypoxia attenuate endothelial nitric oxide production in rat pulmonary arteries by different mechanisms
-
SHAUL, P. W., WELLS, L. B. AND HORNING, K. M.: Acute and prolonged hypoxia attenuate endothelial nitric oxide production in rat pulmonary arteries by different mechanisms. J. Cardiovasc. Pharmacol. 22: 819-827, 1993.
-
(1993)
J. Cardiovasc. Pharmacol.
, vol.22
, pp. 819-827
-
-
Shaul, P.W.1
Wells, L.B.2
Horning, K.M.3
-
36
-
-
0029995775
-
A comparison of pathophysiological changes during hypobaric and normobaric hypoxia in rats
-
SHEEDY, W., THOMPSON, J. S. AND MORICE, A. H.: A comparison of pathophysiological changes during hypobaric and normobaric hypoxia in rats. Resp. 63: 217-222, 1996.
-
(1996)
Resp.
, vol.63
, pp. 217-222
-
-
Sheedy, W.1
Thompson, J.S.2
Morice, A.H.3
-
37
-
-
0028979317
-
Induction of Ca2+/calmodulin-stimulated cyclic AMP phosphodiesterase (PDE1) activity in Chinese hamster ovary cells (CHO) by phorbol 12-myristate 13-acetate and by the selective overexpression of protein kinase C isoforms
-
SPENCE, S., RENA, G., SWEENEY, G. AND HOUSLAY, M. D.: Induction of Ca2+/calmodulin-stimulated cyclic AMP phosphodiesterase (PDE1) activity in Chinese hamster ovary cells (CHO) by phorbol 12-myristate 13-acetate and by the selective overexpression of protein kinase C isoforms. Biochem. J. 310: 975-982, 1995.
-
(1995)
Biochem. J.
, vol.310
, pp. 975-982
-
-
Spence, S.1
Rena, G.2
Sweeney, G.3
Houslay, M.D.4
-
38
-
-
0029992477
-
Complexity and diversity of mammalian adenylyl cyclases
-
SUNAHARA, R. K., DESSAUER, C. W. AND GILMAN, A. G.: Complexity and diversity of mammalian adenylyl cyclases. Ann. Rev. Pharmacol. Toxicol. 36: 461-480, 1996.
-
(1996)
Ann. Rev. Pharmacol. Toxicol.
, vol.36
, pp. 461-480
-
-
Sunahara, R.K.1
Dessauer, C.W.2
Gilman, A.G.3
-
39
-
-
0028824367
-
Contractile responses to sumatriptan in isolated bovine pulmonary artery rings: Relationship to tone and cyclic nucleotide levels
-
SWEENEY, G., TEMPLETON, A., CLAYTON, R. A., BAIRD, M., SHERIDAN, S., JOHNSTON, E. D. AND MACLEAN, M. R.: Contractile responses to sumatriptan in isolated bovine pulmonary artery rings: Relationship to tone and cyclic nucleotide levels. J. Cardiovasc. Pharmacol. 26: 751-760, 1995.
-
(1995)
J. Cardiovasc. Pharmacol.
, vol.26
, pp. 751-760
-
-
Sweeney, G.1
Templeton, A.2
Clayton, R.A.3
Baird, M.4
Sheridan, S.5
Johnston, E.D.6
Maclean, M.R.7
-
41
-
-
0015231739
-
Multiple cyclic nucleotide phosphodiesterase activities from rat brain
-
THOMPSON, W. J. AND APPLEMAN, M. M.: Multiple cyclic nucleotide phosphodiesterase activities from rat brain. Biochemistry 10: 311-316, 1971.
-
(1971)
Biochemistry
, vol.10
, pp. 311-316
-
-
Thompson, W.J.1
Appleman, M.M.2
-
42
-
-
0028808770
-
The cGMP phosphodiesterase inhibitor zaprinast enhances the effect of nitric oxide
-
THUSU, K. G., MORIN, F. C., RUSELL, J. A. AND STEINHORN, R. H.: The cGMP phosphodiesterase inhibitor zaprinast enhances the effect of nitric oxide. Am. J. Resp. Crit. Care Med. 152: 1605-1610, 1995.
-
(1995)
Am. J. Resp. Crit. Care Med.
, vol.152
, pp. 1605-1610
-
-
Thusu, K.G.1
Morin, F.C.2
Rusell, J.A.3
Steinhorn, R.H.4
-
43
-
-
0028171972
-
β-Adrenoceptors, cAMP and airway smooth muscle relaxation - Challenges to the dogma
-
TORPHY, T. J.: β-Adrenoceptors, cAMP and airway smooth muscle relaxation - challenges to the dogma. Trends Pharmacol. Sci. 15: 370-374, 1994.
-
(1994)
Trends Pharmacol. Sci.
, vol.15
, pp. 370-374
-
-
Torphy, T.J.1
-
44
-
-
0015882207
-
Pulmonary hypertension in disorders of the left heart. Observations on catheterisation material
-
TRELL, E.: Pulmonary hypertension in disorders of the left heart. Observations on catheterisation material. Scand. J. Clin. Lab. Invest. 31: 409-418, 1973.
-
(1973)
Scand. J. Clin. Lab. Invest.
, vol.31
, pp. 409-418
-
-
Trell, E.1
-
45
-
-
0028304046
-
Chronic hypoxic pulmonary hypertension - Cell biology to pathophysiology
-
VENDER, R. L.: Chronic hypoxic pulmonary hypertension - cell biology to pathophysiology. Chest 106: 236-243, 1994.
-
(1994)
Chest
, vol.106
, pp. 236-243
-
-
Vender, R.L.1
-
46
-
-
0025976871
-
Increased relaxation by felodipine on pulmonary artery from rats with monocrotaline-induced pulmonary hypertension does not reflect functional impairment of the endothelium
-
WANSTALL, J. C., O'DONNELL, S. R. AND KAY, C. S.: Increased relaxation by felodipine on pulmonary artery from rats with monocrotaline-induced pulmonary hypertension does not reflect functional impairment of the endothelium. Pulmonary Pharmacol. 4: 60-66, 1991.
-
(1991)
Pulmonary Pharmacol.
, vol.4
, pp. 60-66
-
-
Wanstall, J.C.1
O'Donnell, S.R.2
Kay, C.S.3
-
47
-
-
0028608979
-
Distribution of NOS in normoxic vs. hypoxic rat lung: Upregulation of NOS by chronic hypoxia
-
XUE, C., RENGASAMY, A., LE CRAS, T. D., KOBERNA, P. A., DAILEY, C. AND JOHNS, R. A.: Distribution of NOS in normoxic vs. hypoxic rat lung: Upregulation of NOS by chronic hypoxia. Am. J. Physiol. 267: L667-L678, 1994.
-
(1994)
Am. J. Physiol.
, vol.267
-
-
Xue, C.1
Rengasamy, A.2
Le Cras, T.D.3
Koberna, P.A.4
Dailey, C.5
Johns, R.A.6
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