Palladium-mediated annulation of vinyl aziridines with michael acceptors: Stereocontrolled synthesis of substituted pyrrolidines and its application in a formal synthesis of (-)-α-kainic acid

Angewandte Chemie - International Edition

Volumn 50, Issue 28, 2011, Pages 6370-6374

  Lowe, Martin A ^a   Ostovar, Mehrnoosh ^a   Ferrini, Serena ^a   Chen, C Chun ^a   Lawrence, Paul G ^a   Fontana, Francesco ^a   Calabrese, Andrew A ^b   Aggarwal, Varinder K ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

annulation; aziridines; palladium; pyrrolidines; synthetic methods

Indexed keywords

ANNULATION; AZIRIDINES; DIASTEREO-SELECTIVITY; FORMAL SYNTHESIS; KAINIC ACID; METHYL VINYL KETONES; MICHAEL ACCEPTORS; PYRROLIDINES; STEREOCONTROLLED SYNTHESIS; SYNTHETIC METHODS; SYNTHETIC UTILITY;

AMINO ACIDS; KETONES;

ORGANIC COMPOUNDS;

3 BUTEN 2 ONE; 3-BUTEN-2-ONE; ALKANONE; AZIRIDINE DERIVATIVE; KAINIC ACID; PALLADIUM; PYRROLIDINE DERIVATIVE;

ARTICLE; CATALYSIS; CHEMISTRY; CYCLIZATION; STEREOISOMERISM; SYNTHESIS;

AZIRIDINES; BUTANONES; CATALYSIS; CYCLIZATION; KAINIC ACID; PALLADIUM; PYRROLIDINES; STEREOISOMERISM;

EID: 79959748114     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201101389     Document Type: Article

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