Protective effect of Sivelestat in a porcine hepatectomy model prepared using an intermittent Pringle method

European Journal of Pharmacology

Volumn 587, Issue 1-3, 2008, Pages 248-252

  Shimoda, Mitsugi ^a   Iwasaki, Yoshimi ^a   Okada, Toshie ^a   Sawada, Tokihiko ^a   Kubota, Keiichi ^a  

^a DOKKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Intermittent Pringle maneuver; Ischemia reperfusion injury; Liver resection; Nitric oxide; Sivelestat; TNF

Indexed keywords

ASPARTATE AMINOTRANSFERASE; HYALURONIC ACID; INDUCIBLE NITRIC OXIDE SYNTHASE; LACTATE DEHYDROGENASE; LACTIC ACID; LEUKOCYTE ELASTASE; MESSENGER RNA; NITRATE; NITRIC OXIDE SYNTHASE; NITRITE; SIVELESTAT; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD CHEMISTRY; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DRUG EFFECT; DRUG MECHANISM; EXPERIMENTAL MODEL; EXPERIMENTAL PIG; HEART HEMODYNAMICS; HEART RATE; INHIBITION KINETICS; INTERNAL JUGULAR VEIN; LACTATE BLOOD LEVEL; LACTATE DEHYDROGENASE BLOOD LEVEL; LAPAROTOMY; LIVER; LIVER ISCHEMIA; LIVER PROTECTION; LIVER RESECTION; LIVER SINUSOID; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; REPERFUSION INJURY; SPLENIC VEIN; SYSTOLIC BLOOD PRESSURE; VEIN BYPASS;

ANIMALS; ASPARTATE AMINOTRANSFERASES; BLOOD PRESSURE; CELL LINE; ENZYME INHIBITORS; GLYCINE; HEART RATE; HEPATECTOMY; HEPATOCYTES; IN SITU NICK-END LABELING; LEUKOCYTE ELASTASE; LIPOPOLYSACCHARIDES; LIVER DISEASES; NITRIC OXIDE SYNTHASE TYPE II; REPERFUSION INJURY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SERINE PROTEINASE INHIBITORS; SULFONAMIDES; SWINE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 44149111592     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.02.064     Document Type: Article

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