메뉴 건너뛰기




Volumn 106, Issue 4, 2011, Pages 617-633

Desmoglein 2 mutant mice develop cardiac fibrosis and dilation

Author keywords

ARVC; Cardiomyopathy; Desmoglein 2; Desmosome; Mouse model

Indexed keywords

ATRIAL NATRIURETIC FACTOR; BRAIN NATRIURETIC PEPTIDE; CONNECTIVE TISSUE GROWTH FACTOR; DESMOGLEIN 2; GROWTH DIFFERENTIATION FACTOR 15; MYC PROTEIN;

EID: 79959731095     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-011-0175-y     Document Type: Article
Times cited : (69)

References (66)
  • 1
    • 36849060240 scopus 로고    scopus 로고
    • The molecular architecture of cadherins in native epidermal desmosomes
    • DOI 10.1038/nature05994, PII NATURE05994
    • A Al-Amoudi DC Diez MJ Betts AS Frangakis 2007 The molecular architecture of cadherins in native epidermal desmosomes Nature 450 832 837 (Pubitemid 350231314)
    • (2007) Nature , vol.450 , Issue.7171 , pp. 832-837
    • Al-Amoudi, A.1    Diez, D.C.2    Betts, M.J.3    Frangakis, A.S.4
  • 2
    • 42649092901 scopus 로고    scopus 로고
    • Mechanisms of disease: Molecular genetics of arrhythmogenic right ventricular dysplasia/cardiomyopathy
    • DOI 10.1038/ncpcardio1182, PII NCPCARDIO1182
    • MM Awad H Calkins DP Judge 2008 Mechanisms of disease: molecular genetics of arrhythmogenic right ventricular dysplasia/cardiomyopathy Nat Clin Pract Cardiovasc Med 5 258 267 (Pubitemid 351593909)
    • (2008) Nature Clinical Practice Cardiovascular Medicine , vol.5 , Issue.5 , pp. 258-267
    • Awad, M.M.1    Calkins, H.2    Judge, D.P.3
  • 6
    • 57149087666 scopus 로고    scopus 로고
    • Autoantibodies in the autoimmune disease pemphigus foliaceus induce blistering via p38 mitogen-activated protein kinase-dependent signaling in the skin
    • P Berkowitz M Chua Z Liu LA Diaz DS Rubenstein 2008 Autoantibodies in the autoimmune disease pemphigus foliaceus induce blistering via p38 mitogen-activated protein kinase-dependent signaling in the skin Am J Pathol 173 1628 1636
    • (2008) Am J Pathol , vol.173 , pp. 1628-1636
    • Berkowitz, P.1    Chua, M.2    Liu, Z.3    Diaz, L.A.4    Rubenstein, D.S.5
  • 7
    • 0037123593 scopus 로고    scopus 로고
    • C-cadherin ectodomain structure and implications for cell adhesion mechanisms
    • DOI 10.1126/science.1071559
    • TJ Boggon J Murray S Chappuis-Flament E Wong BM Gumbiner L Shapiro 2002 C-cadherin ectodomain structure and implications for cell adhesion mechanisms Science 296 1308 1313 (Pubitemid 34522784)
    • (2002) Science , vol.296 , Issue.5571 , pp. 1308-1313
    • Boggon, T.J.1    Murray, J.2    Chappuis-Flament, S.3    Wong, E.4    Gumbiner, B.M.5    Shapiro, L.6
  • 8
    • 0031874849 scopus 로고    scopus 로고
    • Improved properties of FLP recombinase evolved by cycling mutagenesis
    • DOI 10.1038/nbt0798-657
    • F Buchholz PO Angrand AF Stewart 1998 Improved properties of FLP recombinase evolved by cycling mutagenesis Nat Biotechnol 16 657 662 (Pubitemid 28334324)
    • (1998) Nature Biotechnology , vol.16 , Issue.7 , pp. 657-662
    • Buchholz, F.1    Angrand, P.-O.2    Stewart, A.F.3
  • 9
    • 58149132138 scopus 로고    scopus 로고
    • Arrhythmogenic right ventricular cardiomyopathy/dysplasia: An update
    • H Calkins F Marcus 2008 Arrhythmogenic right ventricular cardiomyopathy/dysplasia: an update Curr Cardiol Rep 10 367 375
    • (2008) Curr Cardiol Rep , vol.10 , pp. 367-375
    • Calkins, H.1    Marcus, F.2
  • 10
    • 0035833265 scopus 로고    scopus 로고
    • Multiple cadherin extracellular repeats mediate homophilic binding and adhesion
    • DOI 10.1083/jcb.200103143
    • S Chappuis-Flament E Wong LD Hicks CM Kay BM Gumbiner 2001 Multiple cadherin extracellular repeats mediate homophilic binding and adhesion J Cell Biol 154 231 243 (Pubitemid 34289291)
    • (2001) Journal of Cell Biology , vol.154 , Issue.1 , pp. 231-243
    • Chappuis-Flament, S.1    Wong, E.2    Hicks, L.D.3    Kay, C.M.4    Gumbiner, B.M.5
  • 11
    • 34250354415 scopus 로고    scopus 로고
    • Desmoglein versus non-desmoglein signaling in pemphigus acantholysis: Characterization of novel signaling pathways downstream of pemphigus vulgaris antigens
    • DOI 10.1074/jbc.M611365200
    • AI Chernyavsky J Arredondo Y Kitajima M Sato-Nagai SA Grando 2007 Desmoglein versus non-desmoglein signaling in pemphigus acantholysis: characterization of novel signaling pathways downstream of pemphigus vulgaris antigens J Biol Chem 282 13804 13812 (Pubitemid 47100562)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.18 , pp. 13804-13812
    • Chernyavsky, A.I.1    Arredondo, J.2    Kitajima, Y.3    Sato-Nagai, M.4    Grando, S.A.5
  • 13
    • 0030610137 scopus 로고    scopus 로고
    • 2+-dependent heterophilic interaction between desmosomal cadherins, desmoglein and desmocollin, contributes to cell-cell adhesion
    • DOI 10.1083/jcb.138.1.193
    • NA Chitaev SM Troyanovsky 1997 Direct Ca2+-dependent heterophilic interaction between desmosomal cadherins, desmoglein and desmocollin, contributes to cell-cell adhesion J Cell Biol 138 193 201 (Pubitemid 27337463)
    • (1997) Journal of Cell Biology , vol.138 , Issue.1 , pp. 193-201
    • Chitaev, N.A.1    Troyanovsky, S.M.2
  • 14
    • 0038380271 scopus 로고    scopus 로고
    • Phenotyping hypertrophy: Eschew obfuscation
    • DOI 10.1161/01.RES.0000077012.11088.BC
    • GW Dorn 2nd J Robbins PH Sugden 2003 Phenotyping hypertrophy: eschew obfuscation Circ Res 92 1171 1175 (Pubitemid 36723642)
    • (2003) Circulation Research , vol.92 , Issue.11 , pp. 1171-1175
    • Dorn II, G.W.1    Robbins, J.2    Sugden, P.H.3
  • 15
    • 1842857530 scopus 로고    scopus 로고
    • Loss of desmoglein 2 suggests essential functions for early embryonic development and proliferation of embryonal stem cells
    • L Eshkind Q Tian A Schmidt WW Franke R Windoffer RE Leube 2002 Loss of desmoglein 2 suggests essential functions for early embryonic development and proliferation of embryonal stem cells Eur J Cell Biol 81 592 598 (Pubitemid 35446792)
    • (2002) European Journal of Cell Biology , vol.81 , Issue.11 , pp. 592-598
    • Eshkind, L.1    Tian, Q.2    Schmidt, A.3    Franke, W.W.4    Windoffer, R.5    Leube, R.E.6
  • 16
    • 38549105509 scopus 로고    scopus 로고
    • Gene expression pattern in biomechanically stretched cardiomyocytes: Evidence for a stretch-specific gene program
    • DOI 10.1161/HYPERTENSIONAHA.107.098046, PII 0000426820080200000025
    • D Frank C Kuhn B Brors C Hanselmann M Ludde HA Katus N Frey 2008 Gene expression pattern in biomechanically stretched cardiomyocytes: evidence for a stretch-specific gene program Hypertension 51 309 318 (Pubitemid 351159944)
    • (2008) Hypertension , vol.51 , Issue.2 , pp. 309-318
    • Frank, D.1    Kuhn, C.2    Brors, B.3    Hanselmann, C.4    Ludde, M.5    Katus, H.A.6    Frey, N.7
  • 18
    • 33745848407 scopus 로고    scopus 로고
    • Suppression of canonical Wnt/β-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy
    • DOI 10.1172/JCI27751
    • E Garcia-Gras R Lombardi MJ Giocondo JT Willerson MD Schneider DS Khoury AJ Marian 2006 Suppression of canonical Wnt/beta-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy J Clin Invest 116 2012 2021 (Pubitemid 44033325)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.7 , pp. 2012-2021
    • Garcia-Gras, E.1    Lombardi, R.2    Giocondo, M.J.3    Willerson, J.T.4    Schneider, M.D.5    Khoury, D.S.6    Marian, A.J.7
  • 19
    • 39849097562 scopus 로고    scopus 로고
    • Desmosome structure, composition and function
    • DOI 10.1016/j.bbamem.2007.07.014, PII S0005273607002751
    • D Garrod M Chidgey 2008 Desmosome structure, composition and function Biochim Biophys Acta 1778 572 587 (Pubitemid 351317796)
    • (2008) Biochimica et Biophysica Acta - Biomembranes , vol.1778 , Issue.3 , pp. 572-587
    • Garrod, D.1    Chidgey, M.2
  • 21
    • 35348927451 scopus 로고    scopus 로고
    • Desmosomes: New perspectives on a classic
    • DOI 10.1038/sj.jid.5701015, PII 5701015
    • KJ Green CL Simpson 2007 Desmosomes: new perspectives on a classic J Invest Dermatol 127 2499 2515 (Pubitemid 47585074)
    • (2007) Journal of Investigative Dermatology , vol.127 , Issue.11 , pp. 2499-2515
    • Green, K.J.1    Simpson, C.L.2
  • 22
    • 34247266577 scopus 로고    scopus 로고
    • Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development
    • DOI 10.1152/physiolgenomics.00163.2006
    • MD Harrell S Harbi JF Hoffman J Zavadil WA Coetzee 2007 Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development Physiol Genomics 28 273 283 (Pubitemid 46708768)
    • (2007) Physiological Genomics , vol.28 , Issue.3 , pp. 273-283
    • Harrell, M.D.1    Harbi, S.2    Hoffman, J.F.3    Zavadil, J.4    Coetzee, W.A.5
  • 23
    • 0141865704 scopus 로고    scopus 로고
    • Untangling desmosomal knots with electron tomography
    • DOI 10.1126/science.1086957
    • W He P Cowin DL Stokes 2003 Untangling desmosomal knots with electron tomography Science 302 109 113 (Pubitemid 37210699)
    • (2003) Science , vol.302 , Issue.5642 , pp. 109-113
    • He, W.1    Cowin, P.2    Stokes, D.L.3
  • 24
    • 61349136209 scopus 로고    scopus 로고
    • Arrhythmogenic right ventricular cardiomyopathy/dysplasia: A not so rare "disease of the desmosome" with multiple clinical presentations
    • T Herren PA Gerber F Duru 2009 Arrhythmogenic right ventricular cardiomyopathy/dysplasia: a not so rare "disease of the desmosome" with multiple clinical presentations Clin Res Cardiol 98 141 158
    • (2009) Clin Res Cardiol , vol.98 , pp. 141-158
    • Herren, T.1    Gerber, P.A.2    Duru, F.3
  • 25
    • 49649084477 scopus 로고    scopus 로고
    • Pemphigus vulgaris IgG directly inhibit desmoglein 3-mediated transinteraction
    • WM Heupel D Zillikens D Drenckhahn J Waschke 2008 Pemphigus vulgaris IgG directly inhibit desmoglein 3-mediated transinteraction J Immunol 181 1825 1834
    • (2008) J Immunol , vol.181 , pp. 1825-1834
    • Heupel, W.M.1    Zillikens, D.2    Drenckhahn, D.3    Waschke, J.4
  • 29
    • 77952784059 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma activation attenuates cardiac fibrosis in type 2 diabetic rats: The effect of rosiglitazone on myocardial expression of receptor for advanced glycation end products and of connective tissue growth factor
    • SH Ihm K Chang HY Kim SH Baek HJ Youn KB Seung JH Kim 2010 Peroxisome proliferator-activated receptor-gamma activation attenuates cardiac fibrosis in type 2 diabetic rats: the effect of rosiglitazone on myocardial expression of receptor for advanced glycation end products and of connective tissue growth factor Basic Res Cardiol 105 399 407
    • (2010) Basic Res Cardiol , vol.105 , pp. 399-407
    • Ihm, S.H.1    Chang, K.2    Kim, H.Y.3    Baek, S.H.4    Youn, H.J.5    Seung, K.B.6    Kim, J.H.7
  • 32
  • 37
    • 0034798853 scopus 로고    scopus 로고
    • Characterisation of postnatal growth of the murine heart
    • DOI 10.1007/s004290100206
    • M Leu E Ehler JC Perriard 2001 Characterisation of postnatal growth of the murine heart Anat Embryol (Berl) 204 217 224 (Pubitemid 32938437)
    • (2001) Anatomy and Embryology , vol.204 , Issue.3 , pp. 217-224
    • Leu, M.1    Ehler, E.2    Perriard, J.-C.3
  • 38
    • 0031252296 scopus 로고    scopus 로고
    • Cre-mediated chromosome loss in mice
    • M Lewandoski GR Martin 1997 Cre-mediated chromosome loss in mice Nat Genet 17 223 225
    • (1997) Nat Genet , vol.17 , pp. 223-225
    • Lewandoski, M.1    Martin, G.R.2
  • 41
    • 0037651250 scopus 로고    scopus 로고
    • A friend within the heart: Natriuretic peptide receptor signaling
    • DOI 10.1172/JCI200318389
    • JD Molkentin 2003 A friend within the heart: natriuretic peptide receptor signaling J Clin Invest 111 1275 1277 (Pubitemid 36554695)
    • (2003) Journal of Clinical Investigation , vol.111 , Issue.9 , pp. 1275-1277
    • Molkentin, J.D.1
  • 42
    • 0029980542 scopus 로고    scopus 로고
    • Structural basis of calcium-induced E-cadherin rigidification and dimerization
    • DOI 10.1038/380360a0
    • B Nagar M Overduin M Ikura JM Rini 1996 Structural basis of calcium-induced E-cadherin rigidification and dimerization Nature 380 360 364 (Pubitemid 26097119)
    • (1996) Nature , vol.380 , Issue.6572 , pp. 360-364
    • Nagar, B.1    Overduin, M.2    Ikura, M.3    Rini, J.M.4
  • 43
    • 30744450770 scopus 로고    scopus 로고
    • The role of natriuretic peptides in cardioprotection
    • DOI 10.1016/j.cardiores.2005.10.001, PII S0008636305004724
    • T Nishikimi N Maeda H Matsuoka 2006 The role of natriuretic peptides in cardioprotection Cardiovasc Res 69 318 328 (Pubitemid 43098788)
    • (2006) Cardiovascular Research , vol.69 , Issue.2 , pp. 318-328
    • Nishikimi, T.1    Maeda, N.2    Matsuoka, H.3
  • 44
    • 0028956981 scopus 로고
    • Solution structure of the epithelial cadherin domain responsible for selective cell adhesion
    • M Overduin TS Harvey S Bagby KI Tong P Yau M Takeichi M Ikura 1995 Solution structure of the epithelial cadherin domain responsible for selective cell adhesion Science 267 386 389
    • (1995) Science , vol.267 , pp. 386-389
    • Overduin, M.1    Harvey, T.S.2    Bagby, S.3    Tong, K.I.4    Yau, P.5    Takeichi, M.6    Ikura, M.7
  • 46
    • 0024383949 scopus 로고
    • Regulation of desmosome assembly in epithelial cells: Kinetics of synthesis, transport, and stabilization of desmoglein I, a major protein of the membrane core domain
    • M Pasdar WJ Nelson 1989 Regulation of desmosome assembly in epithelial cells: kinetics of synthesis, transport, and stabilization of desmoglein I, a major protein of the membrane core domain J Cell Biol 109 163 177 (Pubitemid 19180128)
    • (1989) Journal of Cell Biology , vol.109 , Issue.1 , pp. 163-177
    • Pasdar, M.1    Nelson, W.J.2
  • 51
    • 35548997132 scopus 로고    scopus 로고
    • Role of Genetic Analysis in the Management of Patients With Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy
    • DOI 10.1016/j.jacc.2007.08.008, PII S0735109707026496
    • S Sen-Chowdhry P Syrris WJ McKenna 2007 Role of genetic analysis in the management of patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy J Am Coll Cardiol 50 1813 1821 (Pubitemid 350007965)
    • (2007) Journal of the American College of Cardiology , vol.50 , Issue.19 , pp. 1813-1821
    • Sen-Chowdhry, S.1    Syrris, P.2    McKenna, W.J.3
  • 54
    • 0031669940 scopus 로고    scopus 로고
    • Cellular mechanisms of cardiac hypertrophy
    • DOI 10.1007/s001090050275
    • PH Sugden A Clerk 1998 Cellular mechanisms of cardiac hypertrophy J Mol Med 76 725 746 (Pubitemid 28475168)
    • (1998) Journal of Molecular Medicine , vol.76 , Issue.11 , pp. 725-746
    • Sugden, P.H.1    Clerk, A.2
  • 56
    • 0028340969 scopus 로고
    • Expression and methylation of imprinted genes during in vitro differentiation of mouse parthenogenetic and androgenetic embryonic stem cell lines
    • P Szabo JR Mann 1994 Expression and methylation of imprinted genes during in vitro differentiation of mouse parthenogenetic and androgenetic embryonic stem cell lines Development 120 1651 1660 (Pubitemid 24175906)
    • (1994) Development , vol.120 , Issue.6 , pp. 1651-1660
    • Szabo, P.1    Mann, J.R.2
  • 57
    • 38949159633 scopus 로고    scopus 로고
    • Arrhythmogenic right ventricular cardiomyopathy/dysplasia
    • G Thiene D Corrado C Basso 2007 Arrhythmogenic right ventricular cardiomyopathy/dysplasia Orphanet J Rare Dis 2 45
    • (2007) Orphanet J Rare Dis , vol.2 , pp. 45
    • Thiene, G.1    Corrado, D.2    Basso, C.3
  • 59
    • 14844356653 scopus 로고    scopus 로고
    • Cadherin dimers in cell-cell adhesion
    • DOI 10.1016/j.ejcb.2004.12.009, PII S0171933504000500
    • S Troyanovsky 2005 Cadherin dimers in cell-cell adhesion Eur J Cell Biol 84 225 233 (Pubitemid 40353064)
    • (2005) European Journal of Cell Biology , vol.84 , Issue.2-3 , pp. 225-233
    • Troyanovsky, S.1
  • 60
    • 0032842425 scopus 로고    scopus 로고
    • Mechanism of cell-cell adhesion complex assembly
    • DOI 10.1016/S0955-0674(99)00021-6
    • SM Troyanovsky 1999 Mechanism of cell-cell adhesion complex assembly Curr Opin Cell Biol 11 561 566 (Pubitemid 29460396)
    • (1999) Current Opinion in Cell Biology , vol.11 , Issue.5 , pp. 561-566
    • Troyanovsky, S.M.1
  • 61
    • 33748753687 scopus 로고    scopus 로고
    • Arrhythmogenic right ventricular dysplasia, a cell adhesion cardiomyopathy: Insights into disease pathogenesis from preliminary genotype-phenotype assessment
    • DOI 10.1136/hrt.2005.081679
    • AA Tsatsopoulou NI Protonotarios WJ McKenna 2006 Arrhythmogenic right ventricular dysplasia, a cell adhesion cardiomyopathy: insights into disease pathogenesis from preliminary genotype-phenotype assessment Heart 92 1720 1723 (Pubitemid 44851308)
    • (2006) Heart , vol.92 , Issue.12 , pp. 1720-1723
    • Tsatsopoulou, A.A.1    Protonotarios, N.I.2    McKenna, W.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.