Butin (7,3′,4′-trihydroxydihydroflavone) reduces oxidative stress-induced cell death via inhibition of the mitochondria-dependent apoptotic pathway

International Journal of Molecular Sciences

Volumn 12, Issue 6, 2011, Pages 3871-3887

  Zhang, Rui ^a   Lee, In Kyung ^b   Piao, Mei Jing ^a   Kim, Ki Cheon ^a   Kim, Areum Daseul ^a   Kim, Hye Sun ^b   Chae, Sungwook ^c   Kim, Hee Sun ^d   Hyun, Jin Won ^a  

^a Jeju National University   (South Korea)

^b Seoul National University College of Medicine   (South Korea)

^c Korea Institute of Oriental Medicine (KIOM)   (South Korea)

^d Ewha Womans University School of Medicine   (South Korea)

Author keywords

Butin; Mitochondria dependent apoptotic pathway; Oxidative stress

Indexed keywords

7,3',4' TRIHYDROXYDIHYDROFLAVONE; CASPASE 3; CASPASE 9; CYTOCHROME C; FLAVONOID; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PROTEIN BAX; PROTEIN BCL 2; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; 8-OXO-7-HYDRODEOXYGUANOSINE; ANTIOXIDANT; BENZOPYRAN DERIVATIVE; BROMOCRIPTINE MESILATE; DEOXYGUANOSINE; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 4;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; CYTOSOL; DNA FRAGMENTATION; DRUG STRUCTURE; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; APOPTOSIS; CELL LINE; CHEMISTRY; CRICETULUS; DNA DAMAGE; DRUG EFFECTS; HAMSTER; METABOLISM; TOXICITY;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BENZOPYRANS; CELL LINE; CRICETINAE; CRICETULUS; CYTOCHROMES C; DEOXYGUANOSINE; DNA DAMAGE; HYDROGEN PEROXIDE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE KINASE 4; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-BCL-2; TRANSCRIPTION FACTOR AP-1;

EID: 79959698310     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms12063871     Document Type: Article

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