Clinical, virologic and phylogenetic features of hepatitis B infection in Iranian patients

World Journal of Gastroenterology

Volumn 14, Issue 35, 2008, Pages 5448-5453

  Bahramali, Golnaz ^a   Sadeghizadeh, Majid ^a   Amini Bavil Olyaee, Samad ^b   Alvaian, Seyed Moayed ^c   Behzad Behbahani, Abbas ^d   Adeli, Ahmad ^b   Aghasadeghi, Mohammad Reza ^b   Amini, Safieh ^b   Mahboudi, Fereidoun ^b  

^a TARBIAT MODARES UNIVERSITY   (Iran)

^b PASTEUR INSTITUTE OF IRAN   (Iran)

^c Tehran Hepatitis Center   (Iran)

^d SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Clinical and virologic features; Genetic variability; Hepatitis B virus; Phylogenetic analysis

Indexed keywords

ADENINE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; GUANINE; HEPATITIS B(E) ANTIBODY; HEPATITIS B(E) ANTIGEN; SERINE; THREONINE; HEPATITIS B CORE ANTIGEN; HEPATITIS B SURFACE ANTIGEN;

ADOLESCENT; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASIAN; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CHRONIC HEPATITIS; CLINICAL FEATURE; FEMALE; GENE AMPLIFICATION; GENE SEQUENCE; GENETIC VARIABILITY; GENOTYPE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; IRAN; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PROMOTER REGION; SEROLOGY; VIRAL GENETICS; VIROLOGY; VIRUS CARRIER; BLOOD; CROSS-SECTIONAL STUDY; GENETICS; HETEROZYGOTE; ISOLATION AND PURIFICATION; LIVER TUMOR; MIDDLE AGED; MUTATION; VIRUS GENE;

ADOLESCENT; ADULT; CARCINOMA, HEPATOCELLULAR; CARRIER STATE; CROSS-SECTIONAL STUDIES; FEMALE; GENES, VIRAL; HEPATITIS B; HEPATITIS B CORE ANTIGENS; HEPATITIS B E ANTIGENS; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; IRAN; LIVER CIRRHOSIS; LIVER NEOPLASMS; MALE; MIDDLE AGED; MUTATION; PHYLOGENY; YOUNG ADULT;

EID: 64849109230     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.14.5448     Document Type: Article

References (32)

1. Kao JH, Chen DS. Global control of hepatitis B virus infection. Lancet Infect Dis 2002; 2: 395-403
2. Hannoun C, Horal P, Lindh M. Long-term mutation rates in the hepatitis B virus genome. J Gen Virol 2000; 81: 75-83
3. Kidd-Ljunggren K, Miyakawa Y, Kidd AH. Genetic variability in hepatitis B viruses. J Gen Virol 2002; 83: 1267-1280
4. Kidd-Ljunggren K, Myhre E, Blackberg J. Clinical and serological variation between patients infected with different Hepatitis B virus genotypes. J Clin Microbiol 2004; 42: 5837-5841
5. Tacke F, Manns MP, Trautwein C. Influence of mutations in the hepatitis B virus genome on virus replication and drug resistance - implications for novel antiviral strategies. Curr Med Chem 2004; 11: 2667-2677
6. Chen CH, Lee CM, Hung CH, Hu TH, Wang JH, Wang JC, Lu SN, Changchien CS. Clinical significance and evolution of core promoter and precore mutations in HBeAg-positive patients with HBV genotype B and C: a longitudinal study. Liver Int 2007; 27: 806-815
7. Carman WF. S gene variation of HBV. Acta Gastroenterol Belg 2000; 63: 182-184
8. Verschuere V, Yap PS, Fevery J. Is HBV genotyping of clinical relevance? Acta Gastroenterol Belg 2005; 68: 233-236
9. Alavian SM. Ministry of Health in Iran Is Serious about Controlling Hepatitis B. Hep Mon 2007; 7: 3-5
10. Alavian SM, Fallahian F, Lankarani KB. The changing epidemiology of viral hepatitis B in Iran. J Gastrointestin Liver Dis 2007; 16: 403-406
11. Alizadeh AH, Ranjbar M, Ansari S, MirArab A, Alavian SM, Mohammad K, Adibi P, Sadri GH, Keramat F, Ardalan A, Arabi M, Gharekhani S, Ataei A, Amraei GR, Hosseinzadeh M, Hatami S, Zali M. Seroprevalence of hepatitis B in Nahavand, Islamic Republic of Iran. East Mediterr Health J 2006; 12: 528-537
12. Amini-Bavil-Olyaee S, Hosseini SY, Sabahi F, Alavian SM. Hepatitis B virus (HBV) genotype and YMDD motif mutation profile among patients infected with HBV and untreated with lamivudine. Int J Infect Dis 2008; 12: 83-87
13. Alavian SM, Keyvani H, Rezai M, Ashayeri N, Sadeghi HM. Preliminary report of hepatitis B virus genotype prevalence in Iran. World J Gastroenterol 2006; 12: 5211-5213
14. Amini-Bavil-Olyaee S, Sarrami-Forooshani R, Mahboudi F, Sabahi F, Adeli A, Noorinayer B, Azizi M, Reza Zali M. Genotype characterization and phylogenetic analysis of hepatitis B virus isolates from Iranian patients. J Med Virol 2005; 75: 227-234
15. Mojiri A, Behzad-Behbahani A, Saberifirozi M, Ardabili M, Beheshti M, Rahsaz M, Banihashemi M, Azarpira N, Geramizadeh B, Khadang B, Moaddeb A, Ghaedi M, Heidari T, Torab A, Salah A, Amirzadeh S, Jowkar Z, Mehrabani D, Amini-Bavil-Olyaee S, Dehyadegari MA. Hepatitis B virus genotypes in southwest Iran: molecular, serological and clinical outcomes. World J Gastroenterol 2008; 14: 1510-1513
16. Mohamadnejad M, Pourshams A, Malekzadeh R, Mohamadkhani A, Rajabiani A, Asgari AA, Alimohamadi SM, Razjooyan H, Mamar-Abadi M. Healthy ranges of serum alanine aminotransferase levels in Iranian blood donors. World J Gastroenterol 2003; 9: 2322-2324
17. Amini-Bavil-Olyaee S, Alavian SM, Adeli A, Sarrami-Forooshani R, Sabahi F, Sabouri E, Tavangar HR, Azizi M, Mahboudi F. Hepatitis B virus genotyping, core promoter, and precore/core mutations among Afghan patients infected with hepatitis B: a preliminary report. J Med Virol 2006; 78: 358-364
18. Kumar S, Tamura K, Nei M. MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment. Brief Bioinform 2004; 5: 150-163
19. Rozanov M, Plikat U, Chappey C, Kochergin A, Tatusova T. A web-based genotyping resource for viral sequences. Nucleic Acids Res 2004; 32: W654-W659
20. Amini-Bavil-Olyaee S, Sarrami-Forooshani R, Adeli A, Sabahi F, Abachi M, Azizi M, Mahboudi F. Complete genomic sequence and phylogenetic relatedness of hepatitis B virus isolates from Iran. J Med Virol 2005; 76: 318-326
21. McMahon BJ. Epidemiology and natural history of hepatitis B. Semin Liver Dis 2005; 25 Suppl 1: 3-8
22. Qirbi N, Hall AJ. Epidemiology of hepatitis B virus infection in the Middle East. East Mediterr Health J 2001; 7: 1034-1045
23. Kao JH. Hepatitis B viral genotypes: clinical relevance and molecular characteristics. J Gastroenterol Hepatol 2002; 17: 643-650
24. Kao JH, Chen PJ, Lai MY, Chen DS. Genotypes and clinical phenotypes of hepatitis B virus in patients with chronic hepatitis B virus infection. J Clin Microbiol 2002; 40: 1207-1209
25. Tseng TC, Kao JH. HBV genotype and clinical outcome of chronic hepatitis B: facts and puzzles. Gastroenterology 2008; 134: 1272-1273; author reply 1273
26. Mohebbi SR, Amini-Bavil-Olyaee S, Noorinayer B, Derakhshan F, Chiani M, Rostami Nejad M, Antikchi MH, Sabahi F, Zali MR. Hepatitis B virus molecular epidemiology in Iran. Clin Microbiol Infect 2008; 14: 858-866
27. Carman WF. The clinical significance of surface antigen variants of hepatitis B virus. J Viral Hepat 1997; 4 Suppl 1: 11-20
28. Tian Y, Xu Y, Zhang Z, Meng Z, Qin L, Lu M, Yang D. The amino Acid residues at positions 120 to 123 are crucial for the antigenicity of hepatitis B surface antigen. J Clin Microbiol 2007; 45: 2971-2978
29. Funk ML, Rosenberg DM, Lok AS. World-wide epidemiology of HBeAg-negative chronic hepatitis B and associated precore and core promoter variants. J Viral Hepat 2002; 9: 52-61
30. Chen CH, Lee CM, Lu SN, Changchien CS, Eng HL, Huang CM, Wang JH, Hung CH, Hu TH. Clinical significance of hepatitis B virus (HBV) genotypes and precore and core promoter mutations affecting HBV e antigen expression in Taiwan. J Clin Microbiol 2005; 43: 6000-6006
31. Brunetto MR, Oliveri F, Coco B, Leandro G, Colombatto P, Gorin JM, Bonino F. Outcome of anti-HBe positive chronic hepatitis B in alpha-interferon treated and untreated patients: a long term cohort study. J Hepatol 2002; 36: 263-270
32. Lindh M, Hannoun C, Dhillon AP, Norkrans G, Horal P. Core promoter mutations and genotypes in relation to viral replication and liver damage in East Asian hepatitis B virus carriers. J Infect Dis 1999; 179: 775-782