Cloning and characterization of porcine 4Ig-B7-H3: A potent inhibitor of porcine T-cell activation

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Chen, Weiwei ^b   Hou, Zhibo ^c   Li, Chunman ^c   Xiong, Sheng ^c   Liu, Henggui ^a  

^a INSTITUTE OF PLANT PROTECTION   (China)

^b BEIJING 302 HOSPITAL   (China)

^c JINAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ISOPROTEIN; T LYMPHOCYTE RECEPTOR; B7 ANTIGEN;

3' UNTRANSLATED REGION; 4IG B7 H3 GENE; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOT HYBRIDIZATION; EXPRESSED SEQUENCE TAG; GENE; GENETIC ANALYSIS; GENETIC DATABASE; LYMPHOCYTE FUNCTION; MOLECULAR CLONING; MOUSE; NONHUMAN; OPEN READING FRAME; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; T LYMPHOCYTE ACTIVATION; UPREGULATION; ANIMAL; CHEMISTRY; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; MOLECULAR GENETICS; SWINE; T LYMPHOCYTE;

MURINAE; MUS; SUS;

AMINO ACID SEQUENCE; ANIMALS; B7 ANTIGENS; LYMPHOCYTE ACTIVATION; MOLECULAR SEQUENCE DATA; PROTEIN ISOFORMS; SEQUENCE ALIGNMENT; SWINE; T-LYMPHOCYTES;

EID: 79959581352     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021341     Document Type: Article

References (47)

1. Alegre ML, Frauwirth KA, Thompson CB, (2001) T-cell regulation by CD28 and CTLA-4. Nat Rev Immunol 1: 220-228.
2. Dong C, Juedes AE, Temann UA, Shresta S, Allison JP, et al. (2001) ICOS co-stimulatory receptor is essential for T-cell activation and function. Nature 409: 97-101.
3. Tafuri A, Shahinian A, Bladt F, Yoshinaga SK, Jordana M, et al. (2001) ICOS is essential for effective T-helper-cell responses. Nature 409: 105-109.
4. Latchman Y, Wood CR, Chernova T, Chaudhary D, Borde M, et al. (2001) PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat Immunol 2: 261-268.
5. Selenko-Gebauer N, Majdic O, Szekeres A, Hofler G, Guthann E, et al. (2003) B7-H1 (programmed death-1 ligand) on dendritic cells is involved in the induction and maintenance of T cell anergy. J Immunol 170: 3637-3644.
6. Keir ME, Liang SC, Guleria I, Latchman YE, Qipo A, et al. (2006) Tissue expression of PD-L1 mediates peripheral T cell tolerance. J Exp Med 203: 883-895.
7. Sica GL, Choi IH, Zhu G, Tamada K, Wang SD, et al. (2003) B7-H4, a molecule of the B7 family, negatively regulates T cell immunity. Immunity 18: 849-861.
8. Krambeck AE, Thompson RH, Dong H, Lohse CM, Park ES, et al. (2006) B7-H4 expression in renal cell carcinoma and tumor vasculature: associations with cancer progression and survival. Proc Natl Acad Sci U S A 103: 10391-10396.
9. Yi KH, Chen L, (2009) Fine tuning the immune response through B7-H3 and B7-H4. Immunol Rev 229: 145-151.
10. Chapoval AI, Ni J, Lau JS, Wilcox RA, Flies DB, et al. (2001) B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production. Nat Immunol 2: 269-274.
11. Sun M, Richards S, Prasad DV, Mai XM, Rudensky A, et al. (2002) Characterization of mouse and human B7-H3 genes. J Immunol 168: 6294-6297.
12. Suh WK, Gajewska BU, Okada H, Gronski MA, Bertram EM, et al. (2003) The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses. Nat Immunol 4: 899-906.
13. Steinberger P, Majdic O, Derdak SV, Pfistershammer K, Kirchberger S, et al. (2004) Molecular characterization of human 4Ig-B7-H3, a member of the B7 family with four Ig-like domains. J Immunol 172: 2352-2359.
14. Ling V, Wu PW, Spaulding V, Kieleczawa J, Luxenberg D, et al. (2003) Duplication of primate and rodent B7-H3 immunoglobulin V- and C-like domains: divergent history of functional redundancy and exon loss. Genomics 82: 365-377.
15. Zhang G, Hou J, Shi J, Yu G, Lu B, et al. (2008) Soluble CD276 (B7-H3) is released from monocytes, dendritic cells and activated T cells and is detectable in normal human serum. Immunology 123: 538-546.
16. Prasad DV, Nguyen T, Li Z, Yang Y, Duong J, et al. (2004) Murine B7-H3 is a negative regulator of T cells. J Immunol 173: 2500-2506.
17. Castriconi R, Dondero A, Augugliaro R, Cantoni C, Carnemolla B, et al. (2004) Identification of 4Ig-B7-H3 as a neuroblastoma-associated molecule that exerts a protective role from an NK cell-mediated lysis. Proc Natl Acad Sci U S A 101: 12640-12645.
18. Luo L, Chapoval AI, Flies DB, Zhu G, Hirano F, et al. (2004) B7-H3 enhances tumor immunity in vivo by costimulating rapid clonal expansion of antigen-specific CD8+ cytolytic T cells. J Immunol 173: 5445-5450.
19. Zhang GB, Chen YJ, Shi Q, Ma HB, Ge Y, et al. (2004) Human recombinant B7-H3 expressed in E. coli enhances T lymphocyte proliferation and IL-10 secretion in vitro. Acta Biochim Biophys Sin (Shanghai) 36: 430-436.
20. Loos M, Hedderich DM, Ottenhausen M, Giese NA, Laschinger M, et al. (2009) Expression of the costimulatory molecule B7-H3 is associated with prolonged survival in human pancreatic cancer. BMC Cancer 9: 463.
21. Leitner J, Klauser C, Pickl WF, Stockl J, Majdic O, et al. (2009) B7-H3 is a potent inhibitor of human T-cell activation: No evidence for B7-H3 and TREML2 interaction. Eur J Immunol.
22. Zang X, Allison JP, (2007) The B7 family and cancer therapy: costimulation and coinhibition. Clin Cancer Res 13: 5271-5279.
23. Zang X, Thompson RH, Al-Ahmadie HA, Serio AM, Reuter VE, et al. (2007) B7-H3 and B7x are highly expressed in human prostate cancer and associated with disease spread and poor outcome. Proc Natl Acad Sci U S A 104: 19458-19463.
24. Davis TA, Craighead N, Williams AJ, Scadron A, June CH, et al. (1996) Primary porcine endothelial cells express membrane-bound B7-2 (CD86) and a soluble factor that co-stimulate cyclosporin A-resistant and CD28-dependent human T cell proliferation. Int Immunol 8: 1099-1111.
25. Maher SE, Karmann K, Min W, Hughes CC, Pober JS, et al. (1996) Porcine endothelial CD86 is a major costimulator of xenogeneic human T cells: cloning, sequencing, and functional expression in human endothelial cells. J Immunol 157: 3838-3844.
26. Faas SJ, Giannoni MA, Mickle AP, Kiesecker CL, Reed DJ, et al. (2000) Primary structure and functional characterization of a soluble, alternatively spliced form of B7-1. J Immunol 164: 6340-6348.
27. Jeon DH, Oh K, Oh BC, Nam DH, Kim CH, et al. (2007) Porcine PD-L1: cloning, characterization, and implications during xenotransplantation. Xenotransplantation 14: 236-242.
28. Plege A, Borns K, Baars W, Schwinzer R, (2009) Suppression of human T-cell activation and expansion of regulatory T cells by pig cells overexpressing PD-ligands. Transplantation 87: 975-982.
29. Peng JM, Tian ZJ, Liu HG, An TQ, Zhou YJ, et al. (2010) Cloning and identification of porcine programmed death 1. Vet Immunol Immunopathol 136: 157-162.
30. Agata Y, Kawasaki A, Nishimura H, Ishida Y, Tsubata T, et al. (1996) Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes. Int Immunol 8: 765-772.
31. Zhou YH, Chen YJ, Ma ZY, Xu L, Wang Q, et al. (2007) 4IgB7-H3 is the major isoform expressed on immunocytes as well as malignant cells. Tissue Antigens 70: 96-104.
32. Terzo EA, Alzueta M, Amorena B, de Andres DF, de la Lastra JM, (2005) Molecular cloning and mRNA tissue-expression of two isoforms of the ovine costimulatory molecule CD80 (B7-1). Vet Immunol Immunopathol 103: 9-19.
33. Zhang GB, Dong QM, Xu Y, Yu GH, Zhang XG, (2005) B7-H3: Another Molecule Marker for Mo-DCs? Cell Mol Immunol 2: 307-311.
34. Muthumani K, Choo AY, Shedlock DJ, Laddy DJ, Sundaram SG, et al. (2008) Human immunodeficiency virus type 1 Nef induces programmed death 1 expression through a p38 mitogen-activated protein kinase-dependent mechanism. J Virol 82: 11536-11544.
35. Gao Q, Wang XY, Qiu SJ, Yamato I, Sho M, et al. (2009) Overexpression of PD-L1 Significantly Associates with Tumor Aggressiveness and Postoperative Recurrence in Human Hepatocellular Carcinoma. Clin Cancer Res 15: 971-979.
36. Loos M, Giese NA, Kleeff J, Giese T, Gaida MM, et al. (2008) Clinical significance and regulation of the costimulatory molecule B7-H1 in pancreatic cancer. Cancer Lett.
37. Trabattoni D, Saresella M, Biasin M, Boasso A, Piacentini L, et al. (2003) B7-H1 is up-regulated in HIV infection and is a novel surrogate marker of disease progression. Blood 101: 2514-2520.
38. Barach YS, Lee JS, Zang X, (2010) T cell coinhibition in prostate cancer: new immune evasion pathways and emerging therapeutics. Trends Mol Med.
39. Lee H, Kim JH, Yang SY, Kong J, Oh M, et al. (2010) Peripheral blood gene expression of B7 and CD28 family members associated with tumor progression and microscopic lymphovascular invasion in colon cancer patients. J Cancer Res Clin Oncol 136: 1445-1452.
40. Zang X, Sullivan PS, Soslow RA, Waitz R, Reuter VE, et al. (2010) Tumor associated endothelial expression of B7-H3 predicts survival in ovarian carcinomas. Mod Pathol 23: 1104-1112.
41. Crispen PL, Sheinin Y, Roth TJ, Lohse CM, Kuntz SM, et al. (2008) Tumor cell and tumor vasculature expression of B7-H3 predict survival in clear cell renal cell carcinoma. Clin Cancer Res 14: 5150-5157.
42. Batista L, Pijoan C, Dee S, Olin M, Molitor T, et al. (2004) Virological and immunological responses to porcine reproductive and respiratory syndrome virus in a large population of gilts. Can J Vet Res 68: 267-273.
43. Allende R, Laegreid WW, Kutish GF, Galeota JA, Wills RW, et al. (2000) Porcine reproductive and respiratory syndrome virus: description of persistence in individual pigs upon experimental infection. J Virol 74: 10834-10837.
44. Botner A, Nielsen J, Bille-Hansen V, (1994) Isolation of porcine reproductive and respiratory syndrome (PRRS) virus in a Danish swine herd and experimental infection of pregnant gilts with the virus. Vet Microbiol 40: 351-360.
45. Wang S, Bajorath J, Flies DB, Dong H, Honjo T, et al. (2003) Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction. J Exp Med 197: 1083-1091.
46. Li JC, Lee DC, Cheung BK, Lau AS, (2005) Mechanisms for HIV Tat upregulation of IL-10 and other cytokine expression: kinase signaling and PKR-mediated immune response. FEBS Lett 579: 3055-3062.
47. Yoo J, Chang HH, Bae YH, Seong CN, Choe NH, et al. (2008) Monoclonal antibodies reactive with chicken interleukin-17. Vet Immunol Immunopathol 121: 359-363.