Effect of ginsenoside Rb1 and compound K in chronic oxazolone-induced mouse dermatitis

International Immunopharmacology

Volumn 5, Issue 7-8, 2005, Pages 1183-1191

  Shin, Yong Wook ^a   Bae, Eun Ah ^a   Kim, Sung Soo ^b   Lee, Young Chul ^b   Kim, Dong Hyun ^a  

^a Kyung Hee University   (South Korea)

^b Korea Food Research Institute   (South Korea)

Author keywords

Compound K; COX 2; Ginseng; IL 1 ; Interferon ; Oxazolone induced dermatitis

Indexed keywords

20 O BETA DEXTRO GLUCOPYRANOSYLPROTOPANAXADIOL; CYCLOOXYGENASE 2; GAMMA INTERFERON; GINSENOSIDE RB 1; INTERLEUKIN 1BETA; INTERLEUKIN 4; MESSENGER RNA; OXAZOLONE; PROTOPANAXADIOL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DERMATITIS; DRUG ACTIVITY; DRUG MECHANISM; DRUG POTENCY; EAR; FEMALE; HELPER CELL; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PSORIASIS; RNA ANALYSIS;

ANIMALS; CELL LINE; CHRONIC DISEASE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DERMATITIS, CONTACT; DINOPROSTONE; FEMALE; GINSENOSIDES; MACROPHAGES; MEMBRANE PROTEINS; MICE; MICE, INBRED ICR; NITRIC OXIDE; OXAZOLONE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PSORIASIS; RNA, MESSENGER;

EID: 19544386842     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2005.02.016     Document Type: Article

References (29)

1. L.M. Austin, M. Ozawa, T. Kikuchi, I.B. Walters, and J.G. Krueger The majority of epidermal T cells in psoriasis vulgaris lesions can produce type 1 cytokines, interferon-r, interleukin-2, and tumor necrosis factor-a, defining Tc1 (cytotoxic T lymphocyte) and Th1 effector populations: a type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients J Invest Dermatol 113 1999 752 759
2. B.J. Nicoloff The cytokine network in psoriasis Arch Dermatol 127 1991 871 884
3. J.-M. Ovigne, B.S. Baker, D.W. Brown, A.V. Powles, and L. Fry Epidermal CD8+ T cells in chronic plaque psoriasis are Tc1 cells producing heterogeneous levels of interferon-gamma Exp Dermatol 10 2001 168 174
4. G.L. Hernandez, O.V. Volpert, M.A. Iniguez, E. Lorenzo, S. Martinez-Martinez, and R. Grau Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: roles of the nuclear factor of activated T cells and cyclooxygenase 2 J Exp Med 193 2001 607 620
5. W.H. Boechncke, M. Kock, K. Hardt-Weinelt, M. Wolter, and R. Kaufmann The SCID-hu xenogenic transplantation model allows screening of anti-psoriatic drugs Arch Dermatol Res 291 1999 104 106
6. N.J. Reynolds, J.J. Voorhees, and G.H. Fisher Cyclosporine A inhibits 12-O-tetradecanoyl-phorbol-13-acetate-induced cutaneous inflammation in severe combined immunodeficient mice that lack functional lymphocytes Br J Dermatol 139 1998 16 22
7. Y. Fujii, H. Takeuchi, K. Tanaka, S. Sakuma, Y. Ohkubo, and S. Mutoh Effects of FK-506 (tacrolimus hydrate) on chronic oxazolone-induced dermatitis in rats Eur J Pharmacol 456 2002 115 121
8. N. Tanaka, O. Tanaka, and S. Shibata Chemical studies on the oriental plant drugs: XXVIII. Saponins and sapogenins of ginseng; stereochemistry of sapogenin of ginsenoside Rb1, Rb2 and Rc Chem Pharm Bull 20 1972 1212 1216
9. J.Y. Wu, B.H. Gardner, C.I. Murphy, J.R. Seals, C.R. Kensil, and J. Recchia Saponin adjuvant enhancement of antigen-specific immune responses to an experimental HIV-1 vaccine J Immunol 148 1992 1519 1525
10. M. Mochizuki, C.Y. Yoo, K. Matsuzawa, K. Sato, I. Saiki, and S. Tono-oka Inhibitory effect of tumor metastasis in mice by saponins, ginsenoside Rb2, 20(R)- and 20(S)-ginsenoside Rg3, of Red ginseng Biol Pharm Bull 18 1995 1197 1202
11. C. Wakabayashi, H. Hasegawa, J. Murata, and I. Saiki In vivo antimetastatic action of ginseng protopanaxadiol saponins is based on their intestinal bacterial metabolites after oral administration Oncol Res 9 1998 411 417
12. E.A. Bae, M.J. Han, M.K. Choo, S.Y. Park, and D.H. Kim Metabolism of 20(S)- and 20(R)-ginsenoside Rg3 by human intestinal bacteria and its relation to in vitro biological activities Biol Pharm Bull 25 2002 58 63
13. T. Akao, H. Kida, M. Kanaoka, M. Hattori, and K. Kobashi Intestinal bacterial hydrolysis is required for the appearance of compound K in rat plasma after oral administration of ginsenoside Rb1 from Panax ginseng J Pharm Pharmacol 50 1988 1155 1160
14. H. Hasegawa, J.H. Sung, and Y. Benno Role of human intestinal Prevotella oris in hydrolyzing Ginseng saponis Planta Med 63 1997 436 440
15. S.J. Lee, J.H. Sung, S.J. Lee, C.K. Moon, and B.H. Lee Antitumor activity of a novel ginseng saponin metabolite in human pulmonary adenocarcinoma cells resistant to cisplatin Cancer Lett 144 1999 39 43
16. M.K. Choo, E.K. Park, M.J. Han, and D.H. Kim Antiallergic activity of ginseng and its ginsenoside Planta Med 69 2003 518 522
17. E.K. Park, M.K. Choo, M.J. Han, and D.H. Kim Ginsensodide Rh1 possesses antiallergic and anti-inflammatory activities Int Arch Allergy Immunol 133 2004 113 120
18. Y.S. Chi, H. Lim, H. Park, and H.P. Kim Effect of wogonin, a plant flavone from Scutellariae radix, on skin inflammation: in vivo regulation of inflammation-associated gene expression Biochem Pharmacol 66 2003 1271 1278
19. S.Y. Ryu, M.H. Ock, and K.M. Kim Yomogin inhibits the degranulation of mast cells and the production of nitric oxide in activate in activated RAW 264.7 cells Planta Med 66 2000 171 173
20. M. Schafer-Korting, M.H. Schmid, and H.C. Korting Topical glucocorticoids with improved risk-benefit ratio Drug Safety 14 1996 375 385
21. S. Sakuma, Y. Higashi, N. Sato, T. Sasakawa, T. Sengoku, and Y. Ohkubo Tacrolimus suppressed the production of cytokines involved in atopic dermatitis by direct stimulation of human PBMC system (Comparison with steroids) Int Immunopharmacol 1 2001 1219 1226
22. E.S. Friedman, N. LaNatra, and M.J. Stiller NSAIDs in dermatologic therapy: review and preview J Cutan Med Surg 6 2002 449 459
23. T. Akao, M. Kanaoka, and K. Kobashi Appearance of compound K, a major metabolite of ginsenoside Rb1 by intestinal bacteria, in rat plasma after oral administration-measurement of compound K by enzyme immunoassay Biol Pharm Bull 21 1988 245 249
24. E.A. Bae, S.Y. Park, and D.H. Kim Constitutive β-glucosidases hydrolyzing ginsenoside Rb1 and Rb2 from human intestinal bacteria Biol Pharm Bull 23 2000 1481 1485
25. S.A. Abd-El-Aleem, M.W. Feguson, I. Appleton, A. Bhowmick, C.N. McCollum, and G.W. Ireland Expression of cyclooxygenase isoforms in normal human skin and chromic venous ulcers J Pathol 195 2001 616 623
26. D. Bruch-Gerharz, K. Fehsel, C. Suschek, G. Michel, T. Ruzicka, and V. Kolba-Bachofen A proinflammatory activity of interleukin-8 in human skin: expression of the inducible nitric oxide synthase in psoriatic lesions and cultured keratinocytes J Exp Med 184 1996 2007 2012
27. D. Bruch-Gerharz, T. Ruzicka, and V. Kolb-Bachofen Nitric oxide in human skin: current status and future prospects J Invest Dermatol 110 1998 1 7
28. J.Y. Lee, J.W. Shin, K.S. Chun, K.K. Park, W.Y. Chung, and Y.J. Bang Antitumor promotional effects of a novel intestinal bacterial metabolite (IH-901) derived from the protopanaxadiol-type ginsenosides in mouse skin Carcinogenesis 26 2005 359 367
29. Y.J. Surh, J.Y. Lee, K.J. Choi, and S.R. K Effects of selected ginsenosides on phorbol ester-induced expression of cyclooxygenase-2 and activation of NF-kappa B and ERK1/2 in mouse skin Ann N Y Acad Sci 973 2002 396 401