메뉴 건너뛰기




Volumn 50, Issue 10, 1998, Pages 1155-1160

Intestinal bacterial hydrolysis is required for the appearance of compound K in rat plasma after oral administration of ginsenoside Rb1 from Panax ginseng

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLUCOSIDASE; COMPOUND K; GINSENOSIDE; UNCLASSIFIED DRUG;

EID: 0031736410     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7158.1998.tb03327.x     Document Type: Article
Times cited : (284)

References (23)
  • 1
    • 0028226693 scopus 로고
    • Isolation of a human intestinal anaerobe, Bifidobacterium sp. strain SEN, capable of hydrolyzing sennosides to sennidins
    • Akao, T., Che, Q.-M., Kobashi, K., Yang, L., Hattori, M., Namba, T. (1994a) Isolation of a human intestinal anaerobe, Bifidobacterium sp. strain SEN, capable of hydrolyzing sennosides to sennidins. Appl. Environ. Microbiol. 60: 1041-1043
    • (1994) Appl. Environ. Microbiol. , vol.60 , pp. 1041-1043
    • Akao, T.1    Che, Q.-M.2    Kobashi, K.3    Yang, L.4    Hattori, M.5    Namba, T.6
  • 2
    • 0028559399 scopus 로고
    • Enzymic studies on the animal and intestinal bacterial metabolism of geniposide
    • Akao, T., Kobashi, K., Aburada, M. (1994b) Enzymic studies on the animal and intestinal bacterial metabolism of geniposide Biol. Pharm. Bull. 17: 1573-1576
    • (1994) Biol. Pharm. Bull. , vol.17 , pp. 1573-1576
    • Akao, T.1    Kobashi, K.2    Aburada, M.3
  • 3
    • 85009708837 scopus 로고    scopus 로고
    • 1 by intestinal bacteria, in rat plasma after the oral administration-measurement of compound K by enzyme immunoassay
    • 1 by intestinal bacteria, in rat plasma after the oral administration-measurement of compound K by enzyme immunoassay. Biol. Pharm. Bull. 21: 245-249
    • (1998) Biol. Pharm. Bull. , vol.21 , pp. 245-249
    • Akao, T.1    Kanaoka, M.2    Kobashi, K.3
  • 4
    • 0026087283 scopus 로고
    • Isolation of a human intestinal bacterium capable of transforming barbaloin to aloe-emodin anthrone
    • Che, Q.-M., Akao, T., Hattori, M., Namba, T., Kobashi, K. (1991) Isolation of a human intestinal bacterium capable of transforming barbaloin to aloe-emodin anthrone. Planta Med. 57: 15-19
    • (1991) Planta Med. , vol.57 , pp. 15-19
    • Che, Q.-M.1    Akao, T.2    Hattori, M.3    Namba, T.4    Kobashi, K.5
  • 5
    • 0030757369 scopus 로고    scopus 로고
    • Panax ginseng pharmacology: A nitric oxide link?
    • Gillis, C. N. (1997) Panax ginseng pharmacology: a nitric oxide link? Biochem. Pharmacol. 54: 1-8
    • (1997) Biochem. Pharmacol. , vol.54 , pp. 1-8
    • Gillis, C.N.1
  • 6
    • 0029840531 scopus 로고    scopus 로고
    • Main ginseng saponin metabolites formed by intestinal bacteria
    • Hasegawa, H., Sung, J.-H., Matsumiya, S., Uchiyama, M. (1996) Main ginseng saponin metabolites formed by intestinal bacteria. Planta Med. 62: 453-457
    • (1996) Planta Med. , vol.62 , pp. 453-457
    • Hasegawa, H.1    Sung, J.-H.2    Matsumiya, S.3    Uchiyama, M.4
  • 7
    • 0030864673 scopus 로고    scopus 로고
    • Role of human intestinal Prevotella oris in hydrolyzing ginseng saponins
    • Hasegawa, H., Sung, J.-H., Benno, Y. (1997) Role of human intestinal Prevotella oris in hydrolyzing ginseng saponins. Planta Med. 63: 436-440
    • (1997) Planta Med. , vol.63 , pp. 436-440
    • Hasegawa, H.1    Sung, J.-H.2    Benno, Y.3
  • 8
    • 0021957586 scopus 로고
    • Metabolism of glycyrrhizin by human intestinal flora. II. Isolation and characterization of human intestinal bacteria capable of metabolizing glycyrrhizin and related compounds
    • Hattori, M., Sakamoto, T., Yamagishi, T., Sakamoto, K., Kobashi, K., Namba, T. (1985) Metabolism of glycyrrhizin by human intestinal flora. II. Isolation and characterization of human intestinal bacteria capable of metabolizing glycyrrhizin and related compounds. Chem. Pharm. Bull. 33: 210-217
    • (1985) Chem. Pharm. Bull. , vol.33 , pp. 210-217
    • Hattori, M.1    Sakamoto, T.2    Yamagishi, T.3    Sakamoto, K.4    Kobashi, K.5    Namba, T.6
  • 10
    • 0000370568 scopus 로고
    • Metabolism of ginseng saponins, ginsenosides, by human intestinal flora
    • Kanaoka, M., Akao, T., Kobashi, K. (1994) Metabolism of ginseng saponins, ginsenosides, by human intestinal flora. J. Trad. Med. 11: 241-245
    • (1994) J. Trad. Med. , vol.11 , pp. 241-245
    • Kanaoka, M.1    Akao, T.2    Kobashi, K.3
  • 13
    • 0031451243 scopus 로고    scopus 로고
    • Enzymes responsible for the metabolism of saikosaponins from Eubacterium sp. A-44, a human intestinal anaerobe
    • Kida, H., Akao, T., Meselhy, M. R., Hattori, M. (1997) Enzymes responsible for the metabolism of saikosaponins from Eubacterium sp. A-44, a human intestinal anaerobe. Biol. Pharm. Bull. 20: 1274-1278
    • (1997) Biol. Pharm. Bull. , vol.20 , pp. 1274-1278
    • Kida, H.1    Akao, T.2    Meselhy, M.R.3    Hattori, M.4
  • 14
    • 0022451922 scopus 로고
    • Purification, characterization and reaction mechanism of novel arylsulphotransferase obtained from an anaerobic bacterium of human intestine
    • Kim, D.-H., Konishi, L., Kobashi, K. (1986) Purification, characterization and reaction mechanism of novel arylsulphotransferase obtained from an anaerobic bacterium of human intestine. Biochem. Biophys. Acta. 872: 33-41
    • (1986) Biochem. Biophys. Acta. , vol.872 , pp. 33-41
    • Kim, D.-H.1    Konishi, L.2    Kobashi, K.3
  • 15
    • 0022502851 scopus 로고
    • A novel type of arylsulphotransferase obtained from an anaerobic bacterium of human intestine
    • Kobashi, K., Fukaya, Y., Kim, D.-H., Akao, T., Takebe, S. (1986) A novel type of arylsulphotransferase obtained from an anaerobic bacterium of human intestine. Arch. Biochem. Biophys. 245: 537-539
    • (1986) Arch. Biochem. Biophys. , vol.245 , pp. 537-539
    • Kobashi, K.1    Fukaya, Y.2    Kim, D.-H.3    Akao, T.4    Takebe, S.5
  • 16
    • 0000081802 scopus 로고
    • A review of the biological and pharmacological activities of saponins
    • Lacaille-Dubois, M. A., Wagner, H. (1966) A review of the biological and pharmacological activities of saponins. Phytomedicine 2: 363-386
    • (1966) Phytomedicine , vol.2 , pp. 363-386
    • Lacaille-Dubois, M.A.1    Wagner, H.2
  • 21
    • 0000562916 scopus 로고
    • Chemistry and pharmacology of Panax
    • Wagner, H., Hikino, H., Farnsworth, N. R. (eds) Academic Press, New York
    • Shibata, S., Tanaka, O., Shoji, J., Saito, H. (1985) Chemistry and pharmacology of Panax. In: Wagner, H., Hikino, H., Farnsworth, N. R. (eds) Economic and Medical Plant Research. Vol. 1. Academic Press, New York, pp 217-284
    • (1985) Economic and Medical Plant Research , vol.1 , pp. 217-284
    • Shibata, S.1    Tanaka, O.2    Shoji, J.3    Saito, H.4
  • 23
    • 0029144131 scopus 로고
    • Purification and characterization of a geniposide-hydrolyzing β-glucosidase from Eubacterium sp. A-44, a strict anaerobe from human faeces
    • Yan, L., Akao, T., Kobashi, K. (1995) Purification and characterization of a geniposide-hydrolyzing β-glucosidase from Eubacterium sp. A-44, a strict anaerobe from human faeces. Biol. Pharm. Bull. 18: 1175-1178
    • (1995) Biol. Pharm. Bull. , vol.18 , pp. 1175-1178
    • Yan, L.1    Akao, T.2    Kobashi, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.