In vitro and in vivo study of poly(ethylene glycol) conjugated ibuprofen to extend the duration of action

Scientia Pharmaceutica

Volumn 79, Issue 2, 2011, Pages 359-373

  Nayak, Anjali ^a   Jain, Anurekha ^a  

^a B R NAHATA COLLEGE OF PHARMACY   (India)

Author keywords

Analgesic; Anti inflammatory; Conjugation; Ibuprofen; Poly(ethylene glycol)

Indexed keywords

4 DIMETHYLAMINOPYRIDINE; ACETIC ACID; BUFFER; DICYCLOHEXYLCARBODIIMIDE; IBUPROFEN; MACROGOL 4000;

ACID BASE CATALYSIS; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CATALYSIS; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG HYDROLYSIS; DRUG MECHANISM; DRUG RELEASE; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; ESTERIFICATION; FEMALE; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; MALE; MASS SPECTROMETRY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PAW EDEMA; PH; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; WRITHING TEST;

EID: 79959307994     PISSN: 00368709     EISSN: 22180532     Source Type: Journal    
DOI: 10.3797/scipharm.0911-07     Document Type: Article

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