PEG-metronidazole conjugates: Synthesis, in vitro and in vivo properties

Farmaco

Volumn 60, Issue 9, 2005, Pages 783-788

  Bersani, Cinzia ^a   Berna, Manuela ^a   Pasut, Gianfranco ^a   Veronese, Francesco Maria ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Conjugation; Metronidazole; Pharmacokinetic; Poly(ethylene glycol)

Indexed keywords

ESTER DERIVATIVE; POLY(ETHYLENE GLYCOL) METRONIDAZOLE CONJUGATE; POLYETHYLENE DERIVATIVE; POLYMER; UNCLASSIFIED DRUG;

ACIDITY; ANIMAL EXPERIMENT; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; DEGRADATION; DRUG CONJUGATION; DRUG SOLUBILITY; DRUG SYNTHESIS; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; INTESTINE FLUID; LARGE INTESTINE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; SLOW DRUG RELEASE; SPECTROPHOTOMETER; STOMACH;

ANTIPROTOZOAL AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; METRONIDAZOLE; MOLECULAR WEIGHT; POLYETHYLENE GLYCOLS; SOLUBILITY; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 24944550067     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.farmac.2005.04.015     Document Type: Article

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