Synthesis of poly(ethylene glycol)-metaxalone conjugates and study of its controlled release in vitro

International Journal of Pharmaceutics

Volumn 332, Issue 1-2, 2007, Pages 125-131

  Zhang, Juan ^a   Fan, XiaoDong ^a   Liu, YiFeng ^b   Bo, Lan ^b   Liu, Xiang ^a  

^a NORTHWESTERN POLYTECHNICAL UNIVERSITY   (China)

^b NORTHWEST UNIVERSITY   (China)

Author keywords

Controlled release; Metaxalone; N Chloroacetyl metaxalone; Poly(ethylene glycol); Polymer prodrug

Indexed keywords

MACROGOL; MACROGOL 10000; MACROGOL 4000; MACROGOL 6000; METAXALONE;

ARTICLE; CONTROLLED RELEASE FORMULATION; DRUG CONJUGATION; DRUG HYDROLYSIS; DRUG SYNTHESIS; MOLECULAR WEIGHT; PRIORITY JOURNAL;

ACETIC ACIDS; BUFFERS; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; CHYMOTRYPSIN; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG STABILITY; HALF-LIFE; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; NEUROMUSCULAR AGENTS; OXAZOLIDINONES; POLYETHYLENE GLYCOLS; PRODRUGS; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 33846868640     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.09.039     Document Type: Article

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