-
1
-
-
0001010573
-
The enzymatic phosphorylation of proteins
-
Burnett G, Kennedy EP: The enzymatic phosphorylation of proteins. J Biol Chem 1954; 211: 969-980.
-
(1954)
J Biol Chem
, vol.211
, pp. 969-980
-
-
Burnett, G.1
Kennedy, E.P.2
-
2
-
-
0142244231
-
Phosphorylation state-specific antibodies: Applications in investigative and diagnostic pathology
-
Mandell JW: Phosphorylation state-specific antibodies: applications in investigative and diagnostic pathology. Am J Pathol 2003; 163: 1687-1698.
-
(2003)
Am J Pathol
, vol.163
, pp. 1687-1698
-
-
Mandell, J.W.1
-
3
-
-
19944427133
-
The Janus kinases (Jaks)
-
Yamaoka K, Saharinen P, Pesu M, Holt VE 3rd, Silvennoinen O, O'Shea JJ: The Janus kinases (Jaks). Genome Biol 2004; 5: 253.
-
(2004)
Genome Biol
, vol.5
, pp. 253
-
-
Yamaoka, K.1
Saharinen, P.2
Pesu, M.3
Holt III, V.E.4
Silvennoinen, O.5
O'Shea, J.J.6
-
4
-
-
20144389913
-
The t(8;9)(p22;p24) is a recurrent abnormality in chronic and acute leukemia that fuses PCM1 to JAK2
-
DOI 10.1158/0008-5472.CAN-04-4263
-
Reiter A, Walz C, Watmore A, et al: The t(8; 9)(p22;p24) is a recurrent abnormality in chronic and acute leukemia that fuses PCM1 to JAK2. Cancer Res 2005; 65: 2662-2667. (Pubitemid 40490065)
-
(2005)
Cancer Research
, vol.65
, Issue.7
, pp. 2662-2667
-
-
Reiter, A.1
Walz, C.2
Watmore, A.3
Schoch, C.4
Blau, I.5
Schlegelberger, B.6
Berger, U.7
Telford, N.8
Aruliah, S.9
Yin, J.A.10
Vanstraelen, D.11
Barker, H.F.12
Taylor, P.C.13
O'Driscol, A.14
Benedetti, F.15
Rudolph, C.16
Kolb, H.-J.17
Hochhaus, A.18
Helmann, R.19
Chase, A.20
Cross, N.C.P.21
more..
-
5
-
-
17844383458
-
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
-
DOI 10.1038/nature03546
-
James C, Ugo V, Le Couedic JP, et al: A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 2005; 434: 1144-1148. (Pubitemid 40663494)
-
(2005)
Nature
, vol.434
, Issue.7037
, pp. 1144-1148
-
-
James, C.1
Ugo, V.2
Le, C.J.-P.3
Staerk, J.4
Delhommeau, F.5
Lacout, C.6
Garcon, L.7
Raslova, H.8
Berger, R.9
Bennaceur-Griscelli, A.10
Villeval, J.L.11
Constantinescu, S.N.12
Casadevall, N.13
Vainchenker, W.14
-
6
-
-
20244369569
-
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
-
DOI 10.1016/j.ccr.2005.03.023
-
Levine RL, Wadleigh M, Cools J, et al: Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 2005; 7: 387-397. (Pubitemid 40544655)
-
(2005)
Cancer Cell
, vol.7
, Issue.4
, pp. 387-397
-
-
Levine, R.L.1
Wadleigh, M.2
Cools, J.3
Ebert, B.L.4
Wernig, G.5
Huntly, B.J.P.6
Boggon, T.J.7
Wlodarska, I.8
Clark, J.J.9
Moore, S.10
Adelsperger, J.11
Koo, S.12
Lee, J.C.13
Gabriel, S.14
Mercher, T.15
D'Andrea, A.16
Frohling, S.17
Dohner, K.18
Marynen, P.19
Vandenberghe, P.20
Mesa, R.A.21
Tefferi, A.22
Griffin, J.D.23
Eck, M.J.24
Sellers, W.R.25
Meyerson, M.26
Golub, T.R.27
Lee, S.J.28
Gilliland, D.G.29
more..
-
7
-
-
33846620183
-
Bone marrow phospho-STAT5 expression in non-CML chronic myeloproliferative disorders correlates with JAK2 V617F mutation and provides evidence of in vivo JAK2 activation
-
DOI 10.1097/01.pas.0000213338.25111.d3, PII 0000047820070200000009
-
Aboudola S, Murugesan G, Szpurka H, et al: Bone marrow phospho-STAT5 expression in non-CML chronic myeloproliferative disorders correlates with JAK2 V617F mutation and provides evidence of in vivo JAK2 activation. Am J Surg Pathol 2007; 31: 233-239. (Pubitemid 46175024)
-
(2007)
American Journal of Surgical Pathology
, vol.31
, Issue.2
, pp. 233-239
-
-
Aboudola, S.1
Murugesan, G.2
Szpurka, H.3
Ramsingh, G.4
Zhao, X.5
Prescott, N.6
Tubbs, R.R.7
Maciejewski, J.P.8
Hsi, E.D.9
-
8
-
-
45049087999
-
Phospho-STAT5 expression pattern with the MPL W515L mutation is similar to that seen in chronic myeloproliferative disorders with JAK2 V617F
-
Gibson SE, Schade AE, Szpurka H, Bak B, Maciejewski JP, Hsi ED: Phospho-STAT5 expression pattern with the MPL W515L mutation is similar to that seen in chronic myeloproliferative disorders with JAK2 V617F. Hum Pathol 2008; 39: 1111-1114.
-
(2008)
Hum Pathol
, vol.39
, pp. 1111-1114
-
-
Gibson, S.E.1
Schade, A.E.2
Szpurka, H.3
Bak, B.4
Maciejewski, J.P.5
Hsi, E.D.6
-
9
-
-
0034605042
-
Essential role of signal transducer and activator of transcription (Stat)5a but not Stat5b for Flt3-dependent signaling
-
Zhang S, Fukuda S, Lee Y, et al: Essential role of signal transducer and activator of transcription (Stat)5a but not Stat5b for Flt3-dependent signaling. J Exp Med 2000; 192: 719-728.
-
(2000)
J Exp Med
, vol.192
, pp. 719-728
-
-
Zhang, S.1
Fukuda, S.2
Lee, Y.3
-
10
-
-
0034944794
-
Genomic structure of human FLT3: Implications for mutational analysis [1]
-
DOI 10.1046/j.1365-2141.2001.02821.x
-
Abu-Duhier FM, Goodeve AC, Wilson GA, Care RS, Peake IR, Reilly JT: Genomic structure of human FLT3: implications for mutational analysis. Br J Haematol 2001; 113: 1076-1077. (Pubitemid 32634779)
-
(2001)
British Journal of Haematology
, vol.113
, Issue.4
, pp. 1076-1077
-
-
Abu-Duhier, F.M.1
Goodeve, A.C.2
Wilson, G.A.3
Care, R.S.4
Peake, I.R.5
Reilly, J.T.6
-
11
-
-
0037097716
-
Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: Association with FAB subtypes and identification of subgroups with poor prognosis
-
DOI 10.1182/blood.V99.12.4326
-
Thiede C, Steudel C, Mohr B, et al: Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis. Blood 2002; 99: 4326-4335. (Pubitemid 34627197)
-
(2002)
Blood
, vol.99
, Issue.12
, pp. 4326-4335
-
-
Thiede, C.1
Steudel, C.2
Mohr, B.3
Schaich, M.4
Schakel, U.5
Platzbecker, U.6
Wermke, M.7
Bornhauser, M.8
Ritter, M.9
Neubauer, A.10
Ehninger, G.11
Illmer, T.12
-
12
-
-
16944365287
-
Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines
-
Yokota S, Kiyoi H, Nakao M, et al: Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies: a study on a large series of patients and cell lines. Leukemia 1997; 11: 1605-1609. (Pubitemid 27458595)
-
(1997)
Leukemia
, vol.11
, Issue.10
, pp. 1605-1609
-
-
Yokota, S.1
Kiyoi, H.2
Nakao, M.3
Iwai, T.4
Misawa, T.5
Okuda, T.6
Sonoda, Y.7
Abe, T.8
Kahsima, K.9
Matsuo, Y.10
Naoe, T.11
-
14
-
-
34948903802
-
Cytoplasmic localization of phosphorylated STAT5 in human acute myeloid leukemia is inversely correlated with Flt3-ITD [9]
-
DOI 10.1182/blood-2007-05-090969
-
Bunting KD, Xie XY, Warshawsky I, Hsi ED: Cytoplasmic localization of phosphorylated STAT5 in human acute myeloid leukemia is inversely correlated with Flt3-ITD. Blood 2007; 110: 2775-2776. (Pubitemid 47523213)
-
(2007)
Blood
, vol.110
, Issue.7
, pp. 2775-2776
-
-
Bunting, K.D.1
Xiu, Y.X.2
Warshawsky, I.3
Hsi, E.D.4
-
15
-
-
67651177529
-
Quantitative in situ detection of phosphoproteins in fixed tissues using quantum dot technology
-
Bodo J, Durkin L, Hsi ED: Quantitative in situ detection of phosphoproteins in fixed tissues using quantum dot technology. J Histochem Cytochem 2009; 57: 701-708.
-
(2009)
J Histochem Cytochem
, vol.57
, pp. 701-708
-
-
Bodo, J.1
Durkin, L.2
Hsi, E.D.3
-
16
-
-
34548559124
-
Detection of phospho-STAT5 in mast cells: A reliable phenotypic marker of systemic mast cell disease that reflects constitutive tyrosine kinase activation
-
DOI 10.1111/j.1365-2141.2007.06708.x
-
Zuluaga TT, Hsieh FH, Bodo J, Dong HY, Hsi ED: Detection of phospho-STAT5 in mast cells: a reliable phenotypic marker of systemic mast cell disease that reflects constitutive tyrosine kinase activation. Br J Haematol 2007; 139: 31-40. (Pubitemid 47389913)
-
(2007)
British Journal of Haematology
, vol.139
, Issue.1
, pp. 31-40
-
-
Zuluaga, T.T.1
Hsieh, F.H.2
Bodo, J.3
Dong, H.Y.4
Hsi, E.D.5
-
17
-
-
51849140016
-
Identification and validation of phospho-SRC, a novel and potential pharmacodynamic biomarker for dasatinib (SPRYCEL), a multi-targeted kinase inhibitor
-
Luo FR, Barrett YC, Yang Z, et al: Identification and validation of phospho-SRC, a novel and potential pharmacodynamic biomarker for dasatinib (SPRYCEL), a multi-targeted kinase inhibitor. Cancer Chemother Pharmacol 2008; 62: 1065-1074.
-
(2008)
Cancer Chemother Pharmacol
, vol.62
, pp. 1065-1074
-
-
Luo, F.R.1
Barrett, Y.C.2
Yang, Z.3
-
18
-
-
33645821453
-
Potent inhibition of platelet-derived growth factor-induced responses in vascular smooth muscle cells by BMS-354825 (dasatinib)
-
Chen Z, Lee FY, Bhalla KN, Wu J: Potent inhibition of platelet-derived growth factor-induced responses in vascular smooth muscle cells by BMS-354825 (dasatinib). Mol Pharmacol 2006; 69: 1527-1533.
-
(2006)
Mol Pharmacol
, vol.69
, pp. 1527-1533
-
-
Chen, Z.1
Lee, F.Y.2
Bhalla, K.N.3
Wu, J.4
-
19
-
-
31544459272
-
Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies
-
DOI 10.1158/0008-5472.CAN-05-2050
-
Schittenhelm MM, Shiraga S, Schroeder A, et al: Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies. Cancer Res 2006; 66: 473-481. (Pubitemid 43166056)
-
(2006)
Cancer Research
, vol.66
, Issue.1
, pp. 473-481
-
-
Schittenhelm, M.M.1
Shiraga, S.2
Schroeder, A.3
Corbin, A.S.4
Griffith, D.5
Lee, F.Y.6
Bokemeyer, C.7
Deininger, M.W.N.8
Druker, B.J.9
Heinrich, M.C.10
-
20
-
-
33745102555
-
Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias
-
DOI 10.1056/NEJMoa055229
-
Talpaz M, Shah NP, Kantarjian H, et al: Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias. N Engl J Med 2006; 354: 2531-2541. (Pubitemid 43882349)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.24
, pp. 2531-2541
-
-
Talpaz, M.1
Shah, N.P.2
Kantarjian, H.3
Donato, N.4
Nicoll, J.5
Paquette, R.6
Cortes, J.7
O'Brien, S.8
Nicaise, C.9
Bleickardt, E.10
Blackwood-Chirchir, M.A.11
Iyer, V.12
Chen, T.-T.13
Huang, F.14
Decillis, A.P.15
Sawyers, C.L.16
-
21
-
-
33745283618
-
The structure of dasatinib (BMS-354825) bound to activated ABL kinase domain elucidates its inhibitory activity against imatinib-resistant ABL mutants
-
DOI 10.1158/0008-5472.CAN-05-4187
-
Tokarski JS, Newitt JA, Chang CY, et al: The structure of dasatinib (BMS-354825) bound to activated ABL kinase domain elucidates its inhibitory activity against imatinib-resistant ABL mutants. Cancer Res 2006; 66: 5790-5797. (Pubitemid 43927133)
-
(2006)
Cancer Research
, vol.66
, Issue.11
, pp. 5790-5797
-
-
Tokarski, J.S.1
Newitt, J.A.2
Chang, C.Y.J.3
Cheng, J.D.4
Wittekind, M.5
Kiefer, S.E.6
Kish, K.7
Lee, F.Y.F.8
Borzillerri, R.9
Lombardo, L.J.10
Xie, D.11
Zhang, Y.12
Klei, H.E.13
-
22
-
-
62649102843
-
Choice of fixative is crucial to successful immunohistochemical detection of phosphoproteins in paraffin-embedded tumor tissues
-
Burns JA, Li Y, Cheney CA, et al: Choice of fixative is crucial to successful immunohistochemical detection of phosphoproteins in paraffin-embedded tumor tissues. J Histochem Cytochem 2009; 57: 257-264.
-
(2009)
J Histochem Cytochem
, vol.57
, pp. 257-264
-
-
Burns, J.A.1
Li, Y.2
Cheney, C.A.3
-
23
-
-
20444447110
-
Stability of phosphoprotein as a biological marker of tumor signaling
-
Baker AF, Dragovich T, Ihle NT, Williams R, Fenoglio-Preiser C, Powis G: Stability of phosphoprotein as a biological marker of tumor signaling. Clin Cancer Res 2005; 11: 4338-4340.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4338-4340
-
-
Baker, A.F.1
Dragovich, T.2
Ihle, N.T.3
Williams, R.4
Fenoglio-Preiser, C.5
Powis, G.6
-
24
-
-
55049089416
-
A portrait of tissue phosphoprotein stability in the clinical tissue procurement process
-
Espina V, Edmiston KH, Heiby M, et al: A portrait of tissue phosphoprotein stability in the clinical tissue procurement process. Mol Cell Proteomics 2008; 7: 1998-2018.
-
(2008)
Mol Cell Proteomics
, vol.7
, pp. 1998-2018
-
-
Espina, V.1
Edmiston, K.H.2
Heiby, M.3
-
25
-
-
0027493101
-
Phosphotyrosine-containing proteins are concentrated in differentiating cells during chicken embryonic development
-
Patstone G, Maher PA: Phosphotyrosine-containing proteins are concentrated in differentiating cells during chicken embryonic development. Growth Factors 1993; 9: 243-252. (Pubitemid 23310712)
-
(1993)
Growth Factors
, vol.9
, Issue.3
, pp. 243-252
-
-
Patstone, G.1
Maher, P.A.2
-
26
-
-
45549083112
-
Constitutive activation of signal transducers and activators of transcription predicts vorinostat resistance in cutaneous T-cell lymphoma
-
Fantin VR, Loboda A, Paweletz CP, et al: Constitutive activation of signal transducers and activators of transcription predicts vorinostat resistance in cutaneous T-cell lymphoma. Cancer Res 2008; 68: 3785-3794.
-
(2008)
Cancer Res
, vol.68
, pp. 3785-3794
-
-
Fantin, V.R.1
Loboda, A.2
Paweletz, C.P.3
-
27
-
-
36849065315
-
Global Survey of Phosphotyrosine Signaling Identifies Oncogenic Kinases in Lung Cancer
-
DOI 10.1016/j.cell.2007.11.025, PII S009286740701522X
-
Rikova K, Guo A, Zeng Q, et al: Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Cell 2007; 131: 1190-1203. (Pubitemid 350235027)
-
(2007)
Cell
, vol.131
, Issue.6
, pp. 1190-1203
-
-
Rikova, K.1
Guo, A.2
Zeng, Q.3
Possemato, A.4
Yu, J.5
Haack, H.6
Nardone, J.7
Lee, K.8
Reeves, C.9
Li, Y.10
Hu, Y.11
Tan, Z.12
Stokes, M.13
Sullivan, L.14
Mitchell, J.15
Wetzel, R.16
MacNeill, J.17
Ren, J.M.18
Yuan, J.19
Bakalarski, C.E.20
Villen, J.21
Kornhauser, J.M.22
Smith, B.23
Li, D.24
Zhou, X.25
Gygi, S.P.26
Gu, T.-L.27
Polakiewicz, R.D.28
Rush, J.29
Comb, M.J.30
more..
-
28
-
-
1642463417
-
Analysis of protein phosphorylation and cellular signaling events by flow cytometry: Techniques and clinical applications
-
DOI 10.1016/j.clim.2003.11.009, PII S1521661603003097
-
Krutzik PO, Irish JM, Nolan GP, Perez OD: Analysis of protein phosphorylation and cellular signaling events by flow cytometry: techniques and clinical applications. Clin Immunol 2004; 110: 206-221. (Pubitemid 38402001)
-
(2004)
Clinical Immunology
, vol.110
, Issue.3
, pp. 206-221
-
-
Krutzik, P.O.1
Irish, J.M.2
Nolan, G.P.3
Perez, O.D.4
-
29
-
-
21144445429
-
Phosphotyrosine proteomic study of interferon alpha signaling pathway using a combination of immunoprecipitation and immobilized metal affinity chromatography
-
DOI 10.1074/mcp.M400077-MCP200
-
Zheng H, Hu P, Quinn DF, Wang YK: Phosphotyrosine proteomic study of interferon alpha signaling pathway using a combination of immunoprecipitation and immobilized metal affinity chromatography. Mol Cell Proteomics 2005; 4: 721-730. (Pubitemid 40879601)
-
(2005)
Molecular and Cellular Proteomics
, vol.4
, Issue.6
, pp. 721-730
-
-
Zheng, H.1
Hu, P.2
Quinn, D.F.3
Wang, Y.K.4
-
30
-
-
0035116394
-
A practical approach for evaluating new antibodies in the clinical immunohistochemistry laboratory
-
Hsi ED: A practical approach for evaluating new antibodies in the clinical immunohistochemistry laboratory. Arch Pathol Lab Med 2001; 125: 289-294.
-
(2001)
Arch Pathol Lab Med
, vol.125
, pp. 289-294
-
-
Hsi, E.D.1
|