-
1
-
-
33846620183
-
Bone marrow phospho-STAT5 expression in non-CML chronic myeloproliferative disorders correlates with JAK2 V617F mutation and provides evidence of in vivo JAK2 activation
-
Aboudola S, Murugesan G, Szpurka H, Ramsingh G, Zhao X, Prescott N, Tubbs RR, et al. (2007) Bone marrow phospho-STAT5 expression in non-CML chronic myeloproliferative disorders correlates with JAK2 V617F mutation and provides evidence of in vivo JAK2 activation. Am J Surg Pathol 31:233-239
-
(2007)
Am J Surg Pathol
, vol.31
, pp. 233-239
-
-
Aboudola, S.1
Murugesan, G.2
Szpurka, H.3
Ramsingh, G.4
Zhao, X.5
Prescott, N.6
Tubbs, R.R.7
-
2
-
-
38849096990
-
Expression patterns and predictive value of phosphorylated AKT in early-stage breast cancer
-
Andre F, Nahta R, Conforti R, Boulet T, Aziz M, Yuan LX, Meslin F, et al. (2008) Expression patterns and predictive value of phosphorylated AKT in early-stage breast cancer. Ann Oncol 19:315-320
-
(2008)
Ann Oncol
, vol.19
, pp. 315-320
-
-
Andre, F.1
Nahta, R.2
Conforti, R.3
Boulet, T.4
Aziz, M.5
Yuan, L.X.6
Meslin, F.7
-
3
-
-
20444447110
-
Stability of phosphoprotein as a biological marker of tumor signaling
-
Baker AF, Dragovich T, Ihle NT, Williams R, Fenoglio-Preiser C, Powis G (2005) Stability of phosphoprotein as a biological marker of tumor signaling. Clin Cancer Res 11:4338-4340
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4338-4340
-
-
Baker, A.F.1
Dragovich, T.2
Ihle, N.T.3
Williams, R.4
Fenoglio-Preiser, C.5
Powis, G.6
-
4
-
-
33750452256
-
Signaling interactions of rapamycin combined with erlotinib in cervical carcinoma xenografts
-
Birle DC, Hedley DW (2006) Signaling interactions of rapamycin combined with erlotinib in cervical carcinoma xenografts. Mol Cancer Ther 5:2494-2502
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2494-2502
-
-
Birle, D.C.1
Hedley, D.W.2
-
5
-
-
33745869508
-
Apoptotic effect of ethyl-4-isothiocyanatobuta-noate is associated with DNA damage, proteasomal activity and induction of p53 and p21cip1/waf1
-
Bodo J, Jakubikova J, Chalupa I, Bartosova Z, Horakova K, Floch L, Sedlak J (2006) Apoptotic effect of ethyl-4-isothiocyanatobuta-noate is associated with DNA damage, proteasomal activity and induction of p53 and p21cip1/waf1. Apoptosis 11:1299-1310
-
(2006)
Apoptosis
, vol.11
, pp. 1299-1310
-
-
Bodo, J.1
Jakubikova, J.2
Chalupa, I.3
Bartosova, Z.4
Horakova, K.5
Floch, L.6
Sedlak, J.7
-
6
-
-
34948903802
-
Cytoplasmic localization of phosphorylated STAT5 in human acute myeloid leukemia is inversely correlated with Flt3-ITD
-
Bunting KD, Xie XY, Warshawsky I, Hsi ED (2007) Cytoplasmic localization of phosphorylated STAT5 in human acute myeloid leukemia is inversely correlated with Flt3-ITD. Blood 110:2775-2776
-
(2007)
Blood
, vol.110
, pp. 2775-2776
-
-
Bunting, K.D.1
Xie, X.Y.2
Warshawsky, I.3
Hsi, E.D.4
-
7
-
-
62649102843
-
Choice of fixative is crucial to successful immunohistochemical detection of phosphoproteins in paraffinembedded tumor tissues
-
Burns JA, Li Y, Cheney CA, Ou Y, Franlin-Pfeifer LL, Kuklin N, Zhang ZQ (2009) Choice of fixative is crucial to successful immunohistochemical detection of phosphoproteins in paraffinembedded tumor tissues. J Histochem Cytochem 57:257-264
-
(2009)
J Histochem Cytochem
, vol.57
, pp. 257-264
-
-
Burns, J.A.1
Li, Y.2
Cheney, C.A.3
Ou, Y.4
Franlin-Pfeifer, L.L.5
Kuklin, N.6
Zhang, Z.Q.7
-
8
-
-
0036469182
-
Luminescent quantum dots for multiplexed biological detection and imaging
-
Chan WC, Maxwell DJ, Gao X, Bailey RE, Han M, Nie S (2002) Luminescent quantum dots for multiplexed biological detection and imaging. Curr Opin Biotechnol 13:40-46
-
(2002)
Curr Opin Biotechnol
, vol.13
, pp. 40-46
-
-
Chan, W.C.1
Maxwell, D.J.2
Gao, X.3
Bailey, R.E.4
Han, M.5
Nie, S.6
-
10
-
-
33644677317
-
Coexpression, prognostic significance and predictive value of EGFR, EGFRvIII and phosphorylated EGFR in colorectal cancer
-
Cunningham MP, Essapen S, Thomas H, Green M, Lovell DP, Topham C, Marks C, et al. (2005) Coexpression, prognostic significance and predictive value of EGFR, EGFRvIII and phosphorylated EGFR in colorectal cancer. Int J Oncol 27:317-325
-
(2005)
Int J Oncol
, vol.27
, pp. 317-325
-
-
Cunningham, M.P.1
Essapen, S.2
Thomas, H.3
Green, M.4
Lovell, D.P.5
Topham, C.6
Marks, C.7
-
11
-
-
55049089416
-
A portrait of tissue phosphoprotein stability in the clinical tissue procurement process
-
Espina V, Edmiston KH, Heiby M, Pierobon M, Sciro M, Merritt B, Banks S, et al. (2008) A portrait of tissue phosphoprotein stability in the clinical tissue procurement process. Mol Cell Proteomics 7:1998-2018
-
(2008)
Mol Cell Proteomics
, vol.7
, pp. 1998-2018
-
-
Espina, V.1
Edmiston, K.H.2
Heiby, M.3
Pierobon, M.4
Sciro, M.5
Merritt, B.6
Banks, S.7
-
12
-
-
33846873429
-
Sorafenib in renal cell carcinoma
-
Flaherty KT (2007) Sorafenib in renal cell carcinoma. Clin Cancer Res 13:747s-752s
-
(2007)
Clin Cancer Res
, vol.13
-
-
Flaherty, K.T.1
-
13
-
-
34247610966
-
Divergent cytotoxic effects of PKC412 in combination with conventional antileukemic agents in FLT3 mutation-positive versus -negative leukemia cell lines
-
Furukawa Y, Vu HA, Akutsu M, Odgerel T, Izumi T, Tsunoda S, Matsuo Y, et al. (2007) Divergent cytotoxic effects of PKC412 in combination with conventional antileukemic agents in FLT3 mutation-positive versus -negative leukemia cell lines. Leukemia 21:1005-1014
-
(2007)
Leukemia
, vol.21
, pp. 1005-1014
-
-
Furukawa, Y.1
Vu, H.A.2
Akutsu, M.3
Odgerel, T.4
Izumi, T.5
Tsunoda, S.6
Matsuo, Y.7
-
14
-
-
3543022686
-
In vivo cancer targeting and imaging with semiconductor quantum dots
-
Gao X, Cui Y, Levenson RM, Chung LW, Nie S (2004) In vivo cancer targeting and imaging with semiconductor quantum dots. Nat Biotechnol 22:969-976
-
(2004)
Nat Biotechnol
, vol.22
, pp. 969-976
-
-
Gao, X.1
Cui, Y.2
Levenson, R.M.3
Chung, L.W.4
Nie, S.5
-
15
-
-
0041424802
-
Molecular profiling of single cells and tissue specimens with quantum dots
-
Gao X, Nie S (2003) Molecular profiling of single cells and tissue specimens with quantum dots. Trends Biotechnol 21:371-373
-
(2003)
Trends Biotechnol
, vol.21
, pp. 371-373
-
-
Gao, X.1
Nie, S.2
-
16
-
-
33846342579
-
High throughput quantification of protein expression of cancer antigens in tissue microarray using quantum dot nanocrystals
-
Ghazani AA, Lee JA, Klostranec J, Xiang Q, Dacosta RS,Wilson BC, Tsao MS, et al. (2006) High throughput quantification of protein expression of cancer antigens in tissue microarray using quantum dot nanocrystals. Nano Lett 6:2881-2886
-
(2006)
Nano Lett
, vol.6
, pp. 2881-2886
-
-
Ghazani, A.A.1
Lee, J.A.2
Klostranec, J.3
Xiang, Q.4
Dacosta, R.S.5
Wilson, B.C.6
Tsao, M.S.7
-
18
-
-
16444377912
-
Signal transduction pathways in androgen-dependent and -independent prostate cancer cell proliferation
-
Ghosh PM, Malik SN, Bedolla RG, Wang Y, Mikhailova M, Prihoda TJ, Troyer DA, et al. (2005) Signal transduction pathways in androgen-dependent and -independent prostate cancer cell proliferation. Endocr Relat Cancer 12:119-134
-
(2005)
Endocr Relat Cancer
, vol.12
, pp. 119-134
-
-
Ghosh, P.M.1
Malik, S.N.2
Bedolla, R.G.3
Wang, Y.4
Mikhailova, M.5
Prihoda, T.J.6
Troyer, D.A.7
-
20
-
-
23844521568
-
The protein kinase Cbeta-selective inhibitor, Enzastaurin (LY317615.HCl), suppresses signaling through the AKT pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma xenografts
-
Graff JR, McNulty AM, Hanna KR, Konicek BW, Lynch RL, Bailey SN, Banks C, et al. (2005) The protein kinase Cbeta-selective inhibitor, Enzastaurin (LY317615.HCl), suppresses signaling through the AKT pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma xenografts. Cancer Res 65:7462-7469
-
(2005)
Cancer Res
, vol.65
, pp. 7462-7469
-
-
Graff, J.R.1
McNulty, A.M.2
Hanna, K.R.3
Konicek, B.W.4
Lynch, R.L.5
Bailey, S.N.6
Banks, C.7
-
21
-
-
31844447885
-
Her-2/neu and EGFR tyrosine kinase activation predict the efficacy of trastuzuma b-based therapy in patients with metastatic breast cancer
-
Hudelist G, Kostler WJ, Czerwenka K, Kubista E, Attems J, Muller R, Gschwantler-Kaulich D, et al. (2006) Her-2/neu and EGFR tyrosine kinase activation predict the efficacy of trastuzuma b-based therapy in patients with metastatic breast cancer. Int J Cancer 118:1126-1134
-
(2006)
Int J Cancer
, vol.118
, pp. 1126-1134
-
-
Hudelist, G.1
Kostler, W.J.2
Czerwenka, K.3
Kubista, E.4
Attems, J.5
Muller, R.6
Gschwantler-Kaulich, D.7
-
22
-
-
0023651349
-
A thousand and one protein kinases
-
Hunter T (1987) A thousand and one protein kinases. Cell 50:823-829
-
(1987)
Cell
, vol.50
, pp. 823-829
-
-
Hunter, T.1
-
23
-
-
3242683662
-
Single cell profiling of potentiated phosphoprotein networks in cancer cells
-
Irish JM, Hovland R, Krutzik PO, Perez OD, Bruserud O, Gjertsen BT, Nolan GP (2004) Single cell profiling of potentiated phosphoprotein networks in cancer cells. Cell 118:217-228
-
(2004)
Cell
, vol.118
, pp. 217-228
-
-
Irish, J.M.1
Hovland, R.2
Krutzik, P.O.3
Perez, O.D.4
Bruserud, O.5
Gjertsen, B.T.6
Nolan, G.P.7
-
24
-
-
0037225720
-
Quantum dots finally come of age
-
Jovin TM (2003) Quantum dots finally come of age. Nat Biotechnol 21:32-33
-
(2003)
Nat Biotechnol
, vol.21
, pp. 32-33
-
-
Jovin, T.M.1
-
25
-
-
3442891477
-
Phosphorylation of Akt (Ser473) is an excellent predictor of poor clinical outcome in prostate cancer
-
Kreisberg JI, Malik SN, Prihoda TJ, Bedolla RG, Troyer DA, Kreisberg S, Ghosh PM (2004) Phosphorylation of Akt (Ser473) is an excellent predictor of poor clinical outcome in prostate cancer. Cancer Res 64:5232-5236
-
(2004)
Cancer Res
, vol.64
, pp. 5232-5236
-
-
Kreisberg, J.I.1
Malik, S.N.2
Prihoda, T.J.3
Bedolla, R.G.4
Troyer, D.A.5
Kreisberg, S.6
Ghosh, P.M.7
-
26
-
-
0028353097
-
Phosphorylation and dephosphorylation of protein in regulating cellular function
-
Kurosawa M (1994) Phosphorylation and dephosphorylation of protein in regulating cellular function. J Pharmacol Toxicol Methods 31:135-139
-
(1994)
J Pharmacol Toxicol Methods
, vol.31
, pp. 135-139
-
-
Kurosawa, M.1
-
27
-
-
0346095189
-
Rapid induction of IGF-IR signaling in normal and tumor tissue following intravenous injection of IGF-I in mice
-
Lee AV, Taylor ST, Greenall J, Mills JD, Tonge DW, Zhang P, George J, et al. (2003) Rapid induction of IGF-IR signaling in normal and tumor tissue following intravenous injection of IGF-I in mice. Horm Metab Res 35:651-655
-
(2003)
Horm Metab Res
, vol.35
, pp. 651-655
-
-
Lee, A.V.1
Taylor, S.T.2
Greenall, J.3
Mills, J.D.4
Tonge, D.W.5
Zhang, P.6
George, J.7
-
28
-
-
0742270981
-
Quantum dot ligands provide new insights into erbB/HER receptor-mediated signal transduction
-
Lidke DS, Nagy P, Heintzmann R, Arndt-Jovin DJ, Post JN, Grecco HE, Jares-Erijman EA, et al. (2004) Quantum dot ligands provide new insights into erbB/HER receptor-mediated signal transduction. Nat Biotechnol 22:198-203
-
(2004)
Nat Biotechnol
, vol.22
, pp. 198-203
-
-
Lidke, D.S.1
Nagy, P.2
Heintzmann, R.3
Arndt-Jovin, D.J.4
Post, J.N.5
Grecco, H.E.6
Jares-Erijman, E.A.7
-
29
-
-
0036554734
-
Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer
-
Malik SN, Brattain M, Ghosh PM, Troyer DA, Prihoda T, Bedolla R, Kreisberg JI (2002) Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer. Clin Cancer Res 8:1168-1171
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1168-1171
-
-
Malik, S.N.1
Brattain, M.2
Ghosh, P.M.3
Troyer, D.A.4
Prihoda, T.5
Bedolla, R.6
Kreisberg, J.I.7
-
30
-
-
34147144679
-
Targeting BRAFV600E in thyroid carcinoma: Therapeutic implications
-
Mitsiades CS, Negri J, McMullan C, McMillin DW, Sozopoulos E, Fanourakis G, Voutsinas G, et al. (2007) Targeting BRAFV600E in thyroid carcinoma: therapeutic implications. Mol Cancer Ther 6:1070-1078
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1070-1078
-
-
Mitsiades, C.S.1
Negri, J.2
McMullan, C.3
McMillin, D.W.4
Sozopoulos, E.5
Fanourakis, G.6
Voutsinas, G.7
-
31
-
-
0035117170
-
Quantitative comparison of anti-fading mounting media for confocal laser scanning microscopy
-
Ono M, Murakami T, Kudo A, Isshiki M, Sawada H, Segawa A (2001) Quantitative comparison of anti-fading mounting media for confocal laser scanning microscopy. J Histochem Cytochem 49:305-312
-
(2001)
J Histochem Cytochem
, vol.49
, pp. 305-312
-
-
Ono, M.1
Murakami, T.2
Kudo, A.3
Isshiki, M.4
Sawada, H.5
Segawa, A.6
-
32
-
-
33846936758
-
Prolonged exposure to FLT3 inhibitors leads to resistance via activation of parallel signaling pathways
-
Piloto O, Wright M, Brown P, Kim KT, Levis M, Small D (2007) Prolonged exposure to FLT3 inhibitors leads to resistance via activation of parallel signaling pathways. Blood 109:1643-1652
-
(2007)
Blood
, vol.109
, pp. 1643-1652
-
-
Piloto, O.1
Wright, M.2
Brown, P.3
Kim, K.T.4
Levis, M.5
Small, D.6
-
33
-
-
34447544253
-
BCR-ABL tyrosine kinase inhibitors for chronic myelogenous leukemia
-
Schiffer CA (2007) BCR-ABL tyrosine kinase inhibitors for chronic myelogenous leukemia. N Engl J Med 357:258-265
-
(2007)
N Engl J Med
, vol.357
, pp. 258-265
-
-
Schiffer, C.A.1
-
34
-
-
0035257549
-
Rationale for trastuzumab (Herceptin) in adjuvant breast cancer trials
-
Slamon D, Pegram M (2001) Rationale for trastuzumab (Herceptin) in adjuvant breast cancer trials. Semin Oncol 28(suppl 3):13-19
-
(2001)
Semin Oncol
, vol.28
, Issue.SUPPL. 3
, pp. 13-19
-
-
Slamon, D.1
Pegram, M.2
-
35
-
-
19944427559
-
Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412
-
Stone RM, DeAngelo DJ, Klimek V, Galinsky I, Estey E, Nimer SD, Grandin W, et al. (2005) Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412. Blood 105:54-60
-
(2005)
Blood
, vol.105
, pp. 54-60
-
-
Stone, R.M.1
DeAngelo, D.J.2
Klimek, V.3
Galinsky, I.4
Estey, E.5
Nimer, S.D.6
Grandin, W.7
-
36
-
-
55249101753
-
Quantum dots light up pathology
-
Tholouli E, Sweeney E, Barrow E, Clay V, Hoyland JA, Byers RJ (2008) Quantum dots light up pathology. J Pathol 216:275-285
-
(2008)
J Pathol
, vol.216
, pp. 275-285
-
-
Tholouli, E.1
Sweeney, E.2
Barrow, E.3
Clay, V.4
Hoyland, J.A.5
Byers, R.J.6
-
37
-
-
33947539700
-
Quantum dots for molecular pathology: Their time has arrived
-
True LD, Gao X (2007) Quantum dots for molecular pathology: their time has arrived. J Mol Diagn 9:7-11
-
(2007)
J Mol Diagn
, vol.9
, pp. 7-11
-
-
True, L.D.1
Gao, X.2
-
38
-
-
49649123534
-
Finding what is not there through the unfortunate binding the results: The Mendel effect
-
Wainer H (2006) Finding what is not there through the unfortunate binding the results: the Mendel effect. Chance 19:49-56
-
(2006)
Chance
, vol.19
, pp. 49-56
-
-
Wainer, H.1
-
39
-
-
34548559124
-
Detection of phospho-STAT5 in mast cells: A reliable phenotypic marker of systemic mast cell disease that reflects constitutive tyrosine kinase activation
-
Zuluaga TT, Hsieh FH, Bodo J, Dong HY, Hsi ED (2007) Detection of phospho-STAT5 in mast cells: a reliable phenotypic marker of systemic mast cell disease that reflects constitutive tyrosine kinase activation. Br J Haematol 139:31-40
-
(2007)
Br J Haematol
, vol.139
, pp. 31-40
-
-
Zuluaga, T.T.1
Hsieh, F.H.2
Bodo, J.3
Dong, H.Y.4
Hsi, E.D.5
|