메뉴 건너뛰기




Volumn 31, Issue 2, 1996, Pages 169-178

Chronic administration of eicosapentaenoic acid and docosahexaenoic acid as ethyl esters reduced plasma cholesterol and changed the fatty acid composition in rat blood and organs

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A DEHYDROGENASE; CHOLESTEROL; CORN OIL; DOCOSAHEXAENOIC ACID; FISH OIL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; ICOSAPENTAENOIC ACID; ICOSAPENTAENOIC ACID ETHYL ESTER; OMEGA 3 FATTY ACID; PALMITIC ACID; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

EID: 0030044691     PISSN: 00244201     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02522617     Document Type: Article
Times cited : (97)

References (71)
  • 1
    • 0020684821 scopus 로고
    • The Comparative Reductions of the Plasma Lipids and Lipoproteins by Dietary Polyunsaturated Fats: Salmon Oil Versus Vegetable Oils
    • Harris, W.S., Connor, W.E., and McMurry, M.P. (1983) The Comparative Reductions of the Plasma Lipids and Lipoproteins by Dietary Polyunsaturated Fats: Salmon Oil Versus Vegetable Oils, Metabolism 32, 179-184.
    • (1983) Metabolism , vol.32 , pp. 179-184
    • Harris, W.S.1    Connor, W.E.2    McMurry, M.P.3
  • 2
    • 0021821575 scopus 로고
    • Reduction of Plasma Lipids, Lipoproteins, and Apoproteins by Dietary Fish Oils in Patients with Hypertriglyceridemia
    • Philipson, B.E., Rothrock, D.W., Connor, W.E., Harris, W.S., and Illingsworth. R.D. (1985) Reduction of Plasma Lipids, Lipoproteins, and Apoproteins by Dietary Fish Oils in Patients with Hypertriglyceridemia, N. Engl. J. Med. 312, 1210-1216.
    • (1985) N. Engl. J. Med. , vol.312 , pp. 1210-1216
    • Philipson, B.E.1    Rothrock, D.W.2    Connor, W.E.3    Harris, W.S.4    Illingsworth, R.D.5
  • 3
    • 0021927927 scopus 로고
    • Reduced Triglyceride Formation from Long-Chain Polyenoic Fatty Acids in Rat Hepatocytes
    • Wong, S., Reardon, M., and Nestel, P. (1985) Reduced Triglyceride Formation from Long-Chain Polyenoic Fatty Acids in Rat Hepatocytes, Metabolism 34, 900-905.
    • (1985) Metabolism , vol.34 , pp. 900-905
    • Wong, S.1    Reardon, M.2    Nestel, P.3
  • 4
    • 0021933892 scopus 로고
    • Triglyceride-Lowering Effect of Marine Polyunsaturates in Patients with Hypertriglyceridemia
    • Sanders, T.A.B., Sullivan, D.R., Reeve, J., and Thompson, G.R. (1985) Triglyceride-Lowering Effect of Marine Polyunsaturates in Patients with Hypertriglyceridemia, Arteriosclerosis 5, 459-465.
    • (1985) Arteriosclerosis , vol.5 , pp. 459-465
    • Sanders, T.A.B.1    Sullivan, D.R.2    Reeve, J.3    Thompson, G.R.4
  • 5
    • 0028327342 scopus 로고
    • Omega-3 Fatty Acids. Current Status in Cardiovascular Medicine
    • Schmidt, E.B., and Dyerberg, J. (1994) Omega-3 Fatty Acids. Current Status in Cardiovascular Medicine, Drugs 47, 405-424.
    • (1994) Drugs , vol.47 , pp. 405-424
    • Schmidt, E.B.1    Dyerberg, J.2
  • 6
    • 0024334111 scopus 로고
    • Fish Oils and Plasma Lipid and Lipoprotein Metabolism in Humans: A Critical Review
    • Harris, W.S. (1989) Fish Oils and Plasma Lipid and Lipoprotein Metabolism in Humans: A Critical Review, J. Lipid Res. 30, 785-807.
    • (1989) J. Lipid Res. , vol.30 , pp. 785-807
    • Harris, W.S.1
  • 7
    • 0020456601 scopus 로고
    • Intrahepatic Assembly of Very Low Density Lipoproteins
    • Davis, R.A., and Boogaerts, J.R. (1982) Intrahepatic Assembly of Very Low Density Lipoproteins, J. Biol. Chem. 257, 10908-10913.
    • (1982) J. Biol. Chem. , vol.257 , pp. 10908-10913
    • Davis, R.A.1    Boogaerts, J.R.2
  • 8
    • 0021278243 scopus 로고
    • Suppression by Diets Rich in Fish Oil of Very Low Density Lipoprotein Production in Man
    • Nestel, P.J., Connor, W.E., Reardon, M.F., Connor, S., Wong, S., and Boston, R. (1984) Suppression by Diets Rich in Fish Oil of Very Low Density Lipoprotein Production in Man, J. Clin. Invest. 74, 82-89.
    • (1984) J. Clin. Invest. , vol.74 , pp. 82-89
    • Nestel, P.J.1    Connor, W.E.2    Reardon, M.F.3    Connor, S.4    Wong, S.5    Boston, R.6
  • 9
    • 0022899208 scopus 로고
    • Eicosapentaenoic Acid Inhibits Synthesis and Secretion of Triacylglycerols by Cultured Rat Hepatocytes
    • Nossen, J.Ø., Rustan, A.C., Gloppestad, S.H., Målbakken. S., and Drevon, C.A. (1986) Eicosapentaenoic Acid Inhibits Synthesis and Secretion of Triacylglycerols by Cultured Rat Hepatocytes, Biochim. Biophys. Acta 879, 56-65.
    • (1986) Biochim. Biophys. Acta , vol.879 , pp. 56-65
    • Nossen, J.Ø.1    Rustan, A.C.2    Gloppestad, S.H.3    Målbakken, S.4    Drevon, C.A.5
  • 10
    • 0021333269 scopus 로고
    • The Adaptive Effects of Dietary Fish and Safflower Oil on Lipid and Lipoprotein Metabolism in Perfused Rat Liver
    • Wong, S.H., Nestel, P.J., Trimble, R.P., Storer, G.B., Illman, R.J., and Topping, D.L. (1984) The Adaptive Effects of Dietary Fish and Safflower Oil on Lipid and Lipoprotein Metabolism in Perfused Rat Liver, Biochim. Biophys. Acta 792, 103-109.
    • (1984) Biochim. Biophys. Acta , vol.792 , pp. 103-109
    • Wong, S.H.1    Nestel, P.J.2    Trimble, R.P.3    Storer, G.B.4    Illman, R.J.5    Topping, D.L.6
  • 11
    • 0023103553 scopus 로고
    • Eicosapentaenoic Acid Inhibits the Secretion of Triacylglycerol and of Apoprotein B and the Binding of LDL in Hep G2 Cells
    • Wong, S., and Nestel, P.J. (1987) Eicosapentaenoic Acid Inhibits the Secretion of Triacylglycerol and of Apoprotein B and the Binding of LDL in Hep G2 Cells, Atherosclerosis 64, 139-146.
    • (1987) Atherosclerosis , vol.64 , pp. 139-146
    • Wong, S.1    Nestel, P.J.2
  • 12
    • 0024240921 scopus 로고
    • Inhibition of Apolipoprotein Secretion and Phosphatidate Phosphohydrolase Activity by Eicosapentaenoic and Docosahexaenoic Acids in the Perfused Rat Liver
    • Wong, S.H., and Marsh, J.B. (1988) Inhibition of Apolipoprotein Secretion and Phosphatidate Phosphohydrolase Activity by Eicosapentaenoic and Docosahexaenoic Acids in the Perfused Rat Liver, Metabolism 37, 1177-1181.
    • (1988) Metabolism , vol.37 , pp. 1177-1181
    • Wong, S.H.1    Marsh, J.B.2
  • 13
    • 0023662068 scopus 로고
    • Comparative Effects of Dietary Fish Oil and Carbohydrate on Plasma Lipids and Hepatic Activities of Phosphatidate Phosphohydrolase, Diacylglycerol Acyltransferase and Neutral Lipase Activities in the Rat
    • Marsh, J.B., Topping, D.L., and Nestel, P.J. (1987) Comparative Effects of Dietary Fish Oil and Carbohydrate on Plasma Lipids and Hepatic Activities of Phosphatidate Phosphohydrolase, Diacylglycerol Acyltransferase and Neutral Lipase Activities in the Rat, Biochim. Biophys. Acta, 922, 239-243.
    • (1987) Biochim. Biophys. Acta , vol.922 , pp. 239-243
    • Marsh, J.B.1    Topping, D.L.2    Nestel, P.J.3
  • 14
    • 0024215029 scopus 로고
    • Eicosapentaenoic Acid Reduces Hepatic Synthesis and Secretion of Triacylglycerol by Decreasing the Activity of Acyl-Coenzyme A:1,2-Diacylglycerol Acyltransferase
    • Rustan, A.C., Nossen, J.O., Christiansen, E.N., and Drevon, C.A. (1988) Eicosapentaenoic Acid Reduces Hepatic Synthesis and Secretion of Triacylglycerol by Decreasing the Activity of Acyl-Coenzyme A:1,2-Diacylglycerol Acyltransferase, J. Lipid Res. 29, 1417-1426.
    • (1988) J. Lipid Res. , vol.29 , pp. 1417-1426
    • Rustan, A.C.1    Nossen, J.O.2    Christiansen, E.N.3    Drevon, C.A.4
  • 15
    • 0025163360 scopus 로고
    • On the Effect of Peroxisomal β-Oxidation and Carnitine Palmitoyltransferase Activity by Eicosapentaenoic Acid in Liver and Heart from Rats
    • Aarsland, A., Lundquist, M., Børretsen, B., and Berge, R.K. (1990) On the Effect of Peroxisomal β-Oxidation and Carnitine Palmitoyltransferase Activity by Eicosapentaenoic Acid in Liver and Heart from Rats, Lipids 25, 546-548.
    • (1990) Lipids , vol.25 , pp. 546-548
    • Aarsland, A.1    Lundquist, M.2    Børretsen, B.3    Berge, R.K.4
  • 16
    • 0023929892 scopus 로고
    • Rapid Stimulation of Liver Palmitoyl-CoA Synthetase, Carnitine Palmitoyltransferase and Glycerophosphate Acyltransferase Compared to Peroxisomal β-Oxidation and Palmitoyl-CoA Hydrolase in Rats Fed High-Fat Diets
    • Berge, R.K., Nilsson, A., and Husøy, A.M. (1988) Rapid Stimulation of Liver Palmitoyl-CoA Synthetase, Carnitine Palmitoyltransferase and Glycerophosphate Acyltransferase Compared to Peroxisomal β-Oxidation and Palmitoyl-CoA Hydrolase in Rats Fed High-Fat Diets, Biochim. Biophys. Acta, 960, 417-426.
    • (1988) Biochim. Biophys. Acta , vol.960 , pp. 417-426
    • Berge, R.K.1    Nilsson, A.2    Husøy, A.M.3
  • 17
    • 0025870248 scopus 로고
    • Effect of n-3 Fatty Acids on the Key Enzymes Involved in Cholesterol and Triglyceride Turnover in Rat Liver
    • Al-Shurbaji, A., Larsson-Backström, C., Berglund, L., Eggertson, G., and Björkhem, I. (1991) Effect of n-3 Fatty Acids on the Key Enzymes Involved in Cholesterol and Triglyceride Turnover in Rat Liver, Lipids 26, 385-389.
    • (1991) Lipids , vol.26 , pp. 385-389
    • Al-Shurbaji, A.1    Larsson-Backström, C.2    Berglund, L.3    Eggertson, G.4    Björkhem, I.5
  • 18
    • 0026627936 scopus 로고
    • Evidence for Mechanisms of the Hypotriglyceridemic Effect of n-3 Polyunsaturated Fatty Acids
    • Surette, M.E., Whelan, J., Broughton, K.S., and Kinsella, J.E. (1992) Evidence for Mechanisms of the Hypotriglyceridemic Effect of n-3 Polyunsaturated Fatty Acids, Biochim. Biophys. Acta 1126, 199-205.
    • (1992) Biochim. Biophys. Acta , vol.1126 , pp. 199-205
    • Surette, M.E.1    Whelan, J.2    Broughton, K.S.3    Kinsella, J.E.4
  • 19
    • 0028123672 scopus 로고
    • Effect of Dietary Fish Oil on Blood Levels of Free Fatty Acids, Ketone Bodies and Triacylglycerol in Humans
    • Dagnelie, P.C., Rietveld, T., Swart, G.R., Stijnen. T., and van den Berg, J.W.O. (1994) Effect of Dietary Fish Oil on Blood Levels of Free Fatty Acids, Ketone Bodies and Triacylglycerol in Humans, Lipids 29, 41-4-5.
    • (1994) Lipids , vol.29 , pp. 41-45
    • Dagnelie, P.C.1    Rietveld, T.2    Swart, G.R.3    Stijnen, T.4    Van Den Berg, J.W.O.5
  • 20
    • 0005825963 scopus 로고
    • The Triglyceride-Lowering Effect of Omega-3 Fatty Acids. Is It all in Eicosapentaenoic Acid?
    • Berge, R.K. (1993) The Triglyceride-Lowering Effect of Omega-3 Fatty Acids. Is It all in Eicosapentaenoic Acid? Omega-3 News 1, 5-7.
    • (1993) Omega-3 News , vol.1 , pp. 5-7
    • Berge, R.K.1
  • 21
    • 0025935686 scopus 로고
    • Differential Effects of Fish Oil, Safflower Oil and Palm Oil on Fatty Acid Oxidation and Glycerolipid Synthesis in Rat Liver
    • Halminski, M.A., Marsh, J.B., and Harrison, E.H. (1991) Differential Effects of Fish Oil, Safflower Oil and Palm Oil on Fatty Acid Oxidation and Glycerolipid Synthesis in Rat Liver. J. Nutr. 121, 1554-1561.
    • (1991) J. Nutr. , vol.121 , pp. 1554-1561
    • Halminski, M.A.1    Marsh, J.B.2    Harrison, E.H.3
  • 22
    • 0027498292 scopus 로고
    • Docosahexaenoic Acid Shows No Triglyceride-Lowering Effects but Increases the Peroxisomal Fatty Acid Oxidation in Liver of Rats
    • Willumsen, N., Hexeberg, S., Skorve, J., Lundquist, M., and Berge, R.K. (1993) Docosahexaenoic Acid Shows No Triglyceride-Lowering Effects But Increases the Peroxisomal Fatty Acid Oxidation in Liver of Rats, J. Lipid Res. 34, 13-22.
    • (1993) J. Lipid Res. , vol.34 , pp. 13-22
    • Willumsen, N.1    Hexeberg, S.2    Skorve, J.3    Lundquist, M.4    Berge, R.K.5
  • 23
    • 0027185720 scopus 로고
    • The Hypotriglyceridemic Effect of Eicosapentaenoic Acid in Rats Is Reflected in Increased Mitochondrial Fatty Acid Oxidation Followed by Diminished Lipogenesis
    • Willumsen, N., Skorve, J., Hexeberg, S., Rustan, A.C., and Berge, R.K. (1993) The Hypotriglyceridemic Effect of Eicosapentaenoic Acid in Rats Is Reflected in Increased Mitochondrial Fatty Acid Oxidation Followed by Diminished Lipogenesis, Lipids 28, 683-690.
    • (1993) Lipids , vol.28 , pp. 683-690
    • Willumsen, N.1    Skorve, J.2    Hexeberg, S.3    Rustan, A.C.4    Berge, R.K.5
  • 24
    • 0025863712 scopus 로고
    • Metabolism of n-3 Polyunsaturated Fatty Acids by the Isolated Perfused Rat Liver
    • Zhang, Z.J., Wilcox, H.G., Elam, M.B., Castellani, L.W., and Heimberg, M. (1991) Metabolism of n-3 Polyunsaturated Fatty Acids by the Isolated Perfused Rat Liver, Lipids 26, 504-511.
    • (1991) Lipids , vol.26 , pp. 504-511
    • Zhang, Z.J.1    Wilcox, H.G.2    Elam, M.B.3    Castellani, L.W.4    Heimberg, M.5
  • 25
    • 0021961770 scopus 로고
    • 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase in Peroxisomes in Normal Rat Liver Cells
    • Keller, G.A., Barton, M.C., Shapiro, D.J., and Singer, S.J. (1985) 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase in Peroxisomes in Normal Rat Liver Cells, Proc. Natl. Acad. Sci. USA 82, 770-774.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 770-774
    • Keller, G.A.1    Barton, M.C.2    Shapiro, D.J.3    Singer, S.J.4
  • 26
    • 0023030829 scopus 로고
    • 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Localization in Rat Liver Peroxisomes and Microsomes of Control and Cholestyramine-Treated Animals: Quantitative Biochemical and Immunoelectron Microscopical Analyses
    • Keller, G.A., Pazirandeh, M., and Krisans, S. (1986) 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Localization in Rat Liver Peroxisomes and Microsomes of Control and Cholestyramine-Treated Animals: Quantitative Biochemical and Immunoelectron Microscopical Analyses, J. Cell Biol. 103, 875-886.
    • (1986) J. Cell Biol. , vol.103 , pp. 875-886
    • Keller, G.A.1    Pazirandeh, M.2    Krisans, S.3
  • 27
    • 0018260318 scopus 로고
    • Does Dietary Fat Influence Plasma Lipoprotein Structure?
    • Soutar, A. (1978) Does Dietary Fat Influence Plasma Lipoprotein Structure? Nature 273, 11-12.
    • (1978) Nature , vol.273 , pp. 11-12
    • Soutar, A.1
  • 28
    • 0028284556 scopus 로고
    • Inhibition of Hepatic Chylomicron Remnant Uptake by Gene Transfer of a Receptor Antagonist
    • Willnow, T.E., Sheng, Z., Ishibashi, S., and Herz, J. (1994) Inhibition of Hepatic Chylomicron Remnant Uptake by Gene Transfer of a Receptor Antagonist, Science 264, 1471-1474.
    • (1994) Science , vol.264 , pp. 1471-1474
    • Willnow, T.E.1    Sheng, Z.2    Ishibashi, S.3    Herz, J.4
  • 29
    • 0001665337 scopus 로고
    • Surface Location and High Affinity for Calcium of a 500-kd Liver Membrane Protein Closely Related to the LDL-Receptor suggest a Physiological Role as Lipoprotein Receptor
    • Herz, J., Hamann, U., Rogne, S., Myklebost, O., Gausepohl, H., and Stanley, K.K. (1988) Surface Location and High Affinity for Calcium of a 500-kd Liver Membrane Protein Closely Related to the LDL-Receptor suggest a Physiological Role as Lipoprotein Receptor, EMBO J. 7, 4119-4127.
    • (1988) EMBO J. , vol.7 , pp. 4119-4127
    • Herz, J.1    Hamann, U.2    Rogne, S.3    Myklebost, O.4    Gausepohl, H.5    Stanley, K.K.6
  • 30
    • 0018761890 scopus 로고
    • Active and Inactive Forms of 3-Hydroxy-3-Methylglutaryl-Coenzyme a Reductase in the Liver of the Rat
    • Brown, M.S., Goldstein, J.L., and Dietschy, J.M. (1979) Active and Inactive Forms of 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase in the Liver of the Rat. J. Biol. Chem. 254, 5144-5149.
    • (1979) J. Biol. Chem. , vol.254 , pp. 5144-5149
    • Brown, M.S.1    Goldstein, J.L.2    Dietschy, J.M.3
  • 31
    • 0026010925 scopus 로고
    • Inhibition of Acylcoenzyme A:Cholesterol Acyltransferase Activity by PD128042: Effect on Cholesterol Metabolism and Secretion in CaCo-2 Cells
    • Field, F.J., Albright, E., and Mathur, S. (1991) Inhibition of Acylcoenzyme A:Cholesterol Acyltransferase Activity by PD128042: Effect on Cholesterol Metabolism and Secretion in CaCo-2 Cells. Lipids 26, 1-8.
    • (1991) Lipids , vol.26 , pp. 1-8
    • Field, F.J.1    Albright, E.2    Mathur, S.3
  • 32
    • 0027245925 scopus 로고
    • On the Mechanism of the Hypolipidemic Effect of Sulfur-Substituted Hexadecanedioic Acid (3-Thiadicarboxylic acid) in Normolipidemic Rats
    • Skorve, J., Al-Shurbaji, A., Asiedu, D.K., Björkhem, I., Berglund, L., and Berge, R.K. (1993) On the Mechanism of the Hypolipidemic Effect of Sulfur-Substituted Hexadecanedioic Acid (3-Thiadicarboxylic acid) in Normolipidemic Rats, J. Lipid Res. 34, 1177-1185.
    • (1993) J. Lipid Res. , vol.34 , pp. 1177-1185
    • Skorve, J.1    Al-Shurbaji, A.2    Asiedu, D.K.3    Björkhem, I.4    Berglund, L.5    Berge, R.K.6
  • 33
    • 0024367848 scopus 로고
    • An Improved Pyrogallol Red-Molybdate Method for Determining Total Urinary Protein
    • Orsonneau, J.L., Douet, P., Massoubre, C., Lustenberger, P., and Bernard, S. (1989) An Improved Pyrogallol Red-Molybdate Method for Determining Total Urinary Protein, Clin. Chem. 35, 2233-2236.
    • (1989) Clin. Chem. , vol.35 , pp. 2233-2236
    • Orsonneau, J.L.1    Douet, P.2    Massoubre, C.3    Lustenberger, P.4    Bernard, S.5
  • 34
    • 0023277545 scopus 로고
    • Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate-Phenol-Chloroform Extraction
    • Chomczynski, P., and Sacchi, N. (1987) Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate-Phenol-Chloroform Extraction, Anal. Biochem. 162, 156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 35
    • 0021381028 scopus 로고
    • A Technique for Radiolabeling DNA Restriction Endonuclease Fragments to High Specific Activity
    • Feinberg, A.P., and Vogelstein, B. (1984) A Technique for Radiolabeling DNA Restriction Endonuclease Fragments to High Specific Activity, Anal. Biochem. 137, 266-267.
    • (1984) Anal. Biochem. , vol.137 , pp. 266-267
    • Feinberg, A.P.1    Vogelstein, B.2
  • 37
    • 0023885771 scopus 로고
    • Expression of Oncogenes in Thyroid Tumours: Coexpression of c-erB2/neu and c-erbB
    • Aasland, R., Lillehaug, J.R., Male, R., Josendal, O., Varhaug, I.E., and Kleppe, K. (1988) Expression of Oncogenes in Thyroid Tumours: Coexpression of c-erB2/neu and c-erbB, Br. J. Cancer 57, 358-364.
    • (1988) Br. J. Cancer , vol.57 , pp. 358-364
    • Aasland, R.1    Lillehaug, J.R.2    Male, R.3    Josendal, O.4    Varhaug, I.E.5    Kleppe, K.6
  • 40
    • 0026060744 scopus 로고
    • Peroxisomal Retroconversion of Docosahexaenoic Acid [22:6(n-3)] to Eicosapentaenoic Acid [20:5(n-3)] Studied in Isolated Rat Liver Cells
    • Grønn, M., Christensen, E., Hagve, T-A., and Christophersen, B.O.(1991) Peroxisomal Retroconversion of Docosahexaenoic Acid [22:6(n-3)] to Eicosapentaenoic Acid [20:5(n-3)] Studied in Isolated Rat Liver Cells, Biochim. Biophys. Acta 1081, 85-93.
    • (1991) Biochim. Biophys. Acta , vol.1081 , pp. 85-93
    • Grønn, M.1    Christensen, E.2    Hagve, T.-A.3    Christophersen, B.O.4
  • 41
    • 0026553298 scopus 로고
    • Effects of Dietary Purified Eicosapentaenoic Acid [20:5(n-3)] and Docosahexaenoic Acid [22:6(n-3)] on Fatty Acid Desaturation and Oxidation in Isolated Rat Liver Cells
    • Grønn, M., Christensen, E., Hagve, T.A., and Christophersen, B.O. (1992) Effects of Dietary Purified Eicosapentaenoic Acid [20:5(n-3)] and Docosahexaenoic Acid [22:6(n-3)] on Fatty Acid Desaturation and Oxidation in Isolated Rat Liver Cells, Biochim. Biophys. Acta. 1125, 35-43.
    • (1992) Biochim. Biophys. Acta. , vol.1125 , pp. 35-43
    • Grønn, M.1    Christensen, E.2    Hagve, T.A.3    Christophersen, B.O.4
  • 42
    • 0025841905 scopus 로고
    • The Metabolism of 7,10,33,16,19-Docosapentaenoic Acid to 4,7,10,13,16,19-Docosahexaenoic Acid in Rat Liver Is Independent of a 4-Desaturase
    • Voss, A., Reinhart, M., Sankarappa, S., and Sprecher, H. (1991) The Metabolism of 7,10,33,16,19-Docosapentaenoic Acid to 4,7,10,13,16,19-Docosahexaenoic Acid in Rat Liver Is Independent of a 4-Desaturase, J. Biol. Chem. 266, 19995-20000.
    • (1991) J. Biol. Chem. , vol.266 , pp. 19995-20000
    • Voss, A.1    Reinhart, M.2    Sankarappa, S.3    Sprecher, H.4
  • 43
    • 0023902209 scopus 로고
    • 6-Desaturase Activity in Liver Microsomes of Rats Fed Diets Enriched with Cholesterol and/or ω3 Fatty Acids
    • 6-Desaturase Activity in Liver Microsomes of Rats Fed Diets Enriched with Cholesterol and/or ω3 Fatty Acids, Biochem. J. 249, 351-356.
    • (1988) Biochem. J. , vol.249 , pp. 351-356
    • Garg, M.L.1    Sebokova, E.2    Thomson, A.B.3    Clandimn, M.T.4
  • 44
    • 0028171603 scopus 로고
    • α-Linolenic, Eicosapentaenoic and Docosahexaenoic Acids Affect Lipid Metabolism Differently in Rats
    • Ikeda, I., Wakamatsu, K., Inayoshi, A., Imaizumi, K., Sugano, M., and Yazawa, K. (1994) α-Linolenic, Eicosapentaenoic and Docosahexaenoic Acids Affect Lipid Metabolism Differently in Rats, J. Nutr. 124, 1898-1906.
    • (1994) J. Nutr. , vol.124 , pp. 1898-1906
    • Ikeda, I.1    Wakamatsu, K.2    Inayoshi, A.3    Imaizumi, K.4    Sugano, M.5    Yazawa, K.6
  • 45
    • 0027261298 scopus 로고
    • Regulatory Effects of Individual n-6 and n-3 Polyunsaturated Fatty Acids on LDL Transport in the Rat
    • Spady, D.K. (1993) Regulatory Effects of Individual n-6 and n-3 Polyunsaturated Fatty Acids on LDL Transport in the Rat, J. Lipid Res. 34, 1337-1346.
    • (1993) J. Lipid Res. , vol.34 , pp. 1337-1346
    • Spady, D.K.1
  • 46
    • 0022338088 scopus 로고
    • Metabolism and Effects on Platelet Function of the Purified Eicosapentaenoic and Docosahexaenoic Acids in Humans
    • Von Schacky, C., and Weber, P.C. (1985) Metabolism and Effects on Platelet Function of the Purified Eicosapentaenoic and Docosahexaenoic Acids in Humans, J. Clin. Invest. 76, 2446-2450.
    • (1985) J. Clin. Invest. , vol.76 , pp. 2446-2450
    • Von Schacky, C.1    Weber, P.C.2
  • 47
    • 0027021117 scopus 로고
    • Effects of Purified Eicosapentaenoic Acid Ethyl Ester on Plasma Lipoproteins in Primary Hypercholesterolemia
    • Nozaki, S., Matsuzawa, Y., Hirano, K.I., Sakai, N., Kubo, M., and Tarui, S. (1992) Effects of Purified Eicosapentaenoic Acid Ethyl Ester on Plasma Lipoproteins in Primary Hypercholesterolemia, Int. J. Vitam. Nutr. Res. 62, 256-260.
    • (1992) Int. J. Vitam. Nutr. Res. , vol.62 , pp. 256-260
    • Nozaki, S.1    Matsuzawa, Y.2    Hirano, K.I.3    Sakai, N.4    Kubo, M.5    Tarui, S.6
  • 48
    • 0021169911 scopus 로고
    • Differential Effects of Dietary Eicosapentaenoic and Docosahexaenoic Acids on Lowering of Triglyceride and Cholesterol Levels in the Serum of Rats on Hypercholesterolemic Diet
    • Kobatake, Y., Kuroda, K., Jinnouchi, H., Nishide, E., and Innami, S. (1984) Differential Effects of Dietary Eicosapentaenoic and Docosahexaenoic Acids on Lowering of Triglyceride and Cholesterol Levels in the Serum of Rats on Hypercholesterolemic Diet, J. Nutr. Sci. Vitaminol. Tokyo 30, 357-372.
    • (1984) J. Nutr. Sci. Vitaminol. Tokyo , vol.30 , pp. 357-372
    • Kobatake, Y.1    Kuroda, K.2    Jinnouchi, H.3    Nishide, E.4    Innami, S.5
  • 49
    • 0027078768 scopus 로고
    • Eicosapentaenoic Acid a Hypolipidemic Dose Enhances the Hepatic Antioxidant Defense in Mice
    • Demoz, A., Willumsen, N., and Berge, R.K. (1992). Eicosapentaenoic Acid a Hypolipidemic Dose Enhances the Hepatic Antioxidant Defense in Mice, Lipids 27, 968-971.
    • (1992) Lipids , vol.27 , pp. 968-971
    • Demoz, A.1    Willumsen, N.2    Berge, R.K.3
  • 50
    • 0025608989 scopus 로고
    • Fish Oil Fatty Acids Impair VLDL Assembly and/or Secretion by Cultured Rat Hepatocytes
    • Lang, C.A., and Davis, R.A. (1990) Fish Oil Fatty Acids Impair VLDL Assembly and/or Secretion by Cultured Rat Hepatocytes, J. Lipid Res. 31, 2079-2086.
    • (1990) J. Lipid Res. , vol.31 , pp. 2079-2086
    • Lang, C.A.1    Davis, R.A.2
  • 51
    • 0025116220 scopus 로고
    • The Differential Effect of Eicosapentaenoic Acid and Oleic Acid on Lipid Synthesis and VLDL Secretion in Rabbit Hepatocytes
    • Brenner, K., Sasaki, A., Gowen, D.R., Weaver, A., and Connor, W.E. (1990) The Differential Effect of Eicosapentaenoic Acid and Oleic Acid on Lipid Synthesis and VLDL Secretion in Rabbit Hepatocytes. Lipids 25, 534-540.
    • (1990) Lipids , vol.25 , pp. 534-540
    • Brenner, K.1    Sasaki, A.2    Gowen, D.R.3    Weaver, A.4    Connor, W.E.5
  • 52
    • 0024368071 scopus 로고
    • Effects of Eicosapentaenoic and Docosahexaenoic Acids on Apoprotein B mRNA and Secretion of Very Low Density Lipoprotein in HepG2 Cells
    • Wong, S.H., Fisher, E.A., and Marsh, J.B. (1989) Effects of Eicosapentaenoic and Docosahexaenoic Acids on Apoprotein B mRNA and Secretion of Very Low Density Lipoprotein in HepG2 Cells, Arteriosclerosis 9, 836-841.
    • (1989) Arteriosclerosis , vol.9 , pp. 836-841
    • Wong, S.H.1    Fisher, E.A.2    Marsh, J.B.3
  • 54
    • 0025764461 scopus 로고
    • Effect of 4,7,10,13,16,19-Docosahexaenoic Acid on Triglyceride Accumulation and Secretion in Rat Hepatocytes in Culture
    • Martin, L.J., Reaidi, G.B., Gavino, G.R., and Gavino, V.C. (1991) Effect of 4,7,10,13,16,19-Docosahexaenoic Acid on Triglyceride Accumulation and Secretion in Rat Hepatocytes in Culture, Lipids 26, 374-380.
    • (1991) Lipids , vol.26 , pp. 374-380
    • Martin, L.J.1    Reaidi, G.B.2    Gavino, G.R.3    Gavino, V.C.4
  • 55
    • 0018195638 scopus 로고
    • 22-Unsaturated Fatty Acids in Reducing Fatty Acid Synthesis in Isolated Rat Hepatocytes
    • 22-Unsaturated Fatty Acids in Reducing Fatty Acid Synthesis in Isolated Rat Hepatocytes, Biochim. Biophys. Acta 531, 133-140.
    • (1978) Biochim. Biophys. Acta , vol.531 , pp. 133-140
    • Yang, Y.T.1    Williams, M.A.2
  • 56
    • 0009017989 scopus 로고
    • Effects of Certain Pure Long Chain Polyunsaturated Fatty Acid Esters on the Blood Lipids of Man
    • Worne, H.E., and Smith, L.W. (1959) Effects of Certain Pure Long Chain Polyunsaturated Fatty Acid Esters on the Blood Lipids of Man, Am. J. Med. Sci. 237, 710-721.
    • (1959) Am. J. Med. Sci. , vol.237 , pp. 710-721
    • Worne, H.E.1    Smith, L.W.2
  • 57
    • 0024488180 scopus 로고
    • Effect of Oral Administration of Highly Purified Eicosapentaenoic Acid and Docosahexaenoic Acid on Platelet Function and Serum Lipids in Hyperlipidemic Patients
    • (Samuelsen, B., Wong, P.Y.-K., and Sun, F.F., eds.) Raven Press, New York
    • Hirai, A., Terano, T., Makuta, H., Ozawa, A., Fujita, T., Tamura, Y., and Yoshida, S. (1989) Effect of Oral Administration of Highly Purified Eicosapentaenoic Acid and Docosahexaenoic Acid on Platelet Function and Serum Lipids in Hyperlipidemic Patients, in Advances in Prostaglandin, Thromboxane, and Leukotriene Research (Samuelsen, B., Wong, P.Y.-K., and Sun, F.F., eds.) Vol. 19, pp. 627-630, Raven Press, New York.
    • (1989) Advances in Prostaglandin, Thromboxane, and Leukotriene Research , vol.19 , pp. 627-630
    • Hirai, A.1    Terano, T.2    Makuta, H.3    Ozawa, A.4    Fujita, T.5    Tamura, Y.6    Yoshida, S.7
  • 59
    • 0019855636 scopus 로고
    • Effect on Blood Lipids and Haemostasis of a Supplement of Cod-Liver Oil, Rich in Eicosapentaenoic and Docosahexaenoic Acids, in Healthy Young Men
    • Sanders, T.A.B., Vickers, M., and Haines, A.P. (1981) Effect on Blood Lipids and Haemostasis of a Supplement of Cod-Liver Oil, Rich in Eicosapentaenoic and Docosahexaenoic Acids, in Healthy Young Men, Clin. Sci 61, 317-324.
    • (1981) Clin. Sci , vol.61 , pp. 317-324
    • Sanders, T.A.B.1    Vickers, M.2    Haines, A.P.3
  • 61
    • 0021821575 scopus 로고
    • Reduction of Plasma Lipids, Lipoproteins and Apoproteins by Dietary Fish Oil in Patients with Hypertriglyceridemia
    • Phillipson, B.E., Rothroch, D.W., Connor, W.E., Harris, W.S., and Illingsworth, D.R. (1985) Reduction of Plasma Lipids, Lipoproteins and Apoproteins by Dietary Fish Oil in Patients with Hypertriglyceridemia, N. Engl. J. Med. 312, 1210-1216.
    • (1985) N. Engl. J. Med. , vol.312 , pp. 1210-1216
    • Phillipson, B.E.1    Rothroch, D.W.2    Connor, W.E.3    Harris, W.S.4    Illingsworth, D.R.5
  • 62
    • 0020571986 scopus 로고
    • The Effect of n-6 and n-3 Polyunsaturated Fatty Acids on Haemostasis, Blood Pressure, Bleeding Time, Hematology and Clinical Chemistry in Healthy Males
    • Mortensen, J.Z., Schmidt, E.B., Nielsen, A.H., and Dyerberg, J. (1983) The Effect of n-6 and n-3 Polyunsaturated Fatty Acids on Haemostasis, Blood Pressure, Bleeding Time, Hematology and Clinical Chemistry in Healthy Males, Thromb. Haemost. 50, 543-546.
    • (1983) Thromb. Haemost. , vol.50 , pp. 543-546
    • Mortensen, J.Z.1    Schmidt, E.B.2    Nielsen, A.H.3    Dyerberg, J.4
  • 63
    • 0019789469 scopus 로고
    • The Effect of Various Intakes of Omega-3 Fatty Acids on Blood Lipid Composition in Healthy Human Subjects
    • Bronsgeest-Schoute, H.C., Van Gent, C.M., Luten, G.B., and Ruiter, A. (1981) The Effect of Various Intakes of Omega-3 Fatty Acids on Blood Lipid Composition in Healthy Human Subjects, Am. J. Clin. Nutr. 34, 1752-1757.
    • (1981) Am. J. Clin. Nutr. , vol.34 , pp. 1752-1757
    • Bronsgeest-Schoute, H.C.1    Van Gent, C.M.2    Luten, G.B.3    Ruiter, A.4
  • 64
    • 0022452424 scopus 로고
    • Paradoxical Elevation of LDL Apoprotein B Levels in Hypertriglyceridaemic Patients and Normal Subjects Ingesting Fish Oil
    • Sullivan, D.R., Sanders, T.A.B., Trayner, I.M., and Thompson, G.R. (1986) Paradoxical Elevation of LDL Apoprotein B Levels in Hypertriglyceridaemic Patients and Normal Subjects Ingesting Fish Oil, Atherosclerosis 61, 129-134.
    • (1986) Atherosclerosis , vol.61 , pp. 129-134
    • Sullivan, D.R.1    Sanders, T.A.B.2    Trayner, I.M.3    Thompson, G.R.4
  • 65
    • 0026932050 scopus 로고
    • The Role of Peroxisomes in Cholesterol Metabolism
    • Krisans, S.K. (1992) The Role of Peroxisomes in Cholesterol Metabolism, Am. J. Respir. Cell Mol. Biol. 7, 358-364.
    • (1992) Am. J. Respir. Cell Mol. Biol. , vol.7 , pp. 358-364
    • Krisans, S.K.1
  • 66
    • 0024332088 scopus 로고
    • Biosynthesis of Dolichol by Rat Liver Peroxisomes
    • Appelkvist, E.L., and Kalén, A. (1989) Biosynthesis of Dolichol by Rat Liver Peroxisomes, Eur. J. Biochem. 185, 503-509.
    • (1989) Eur. J. Biochem. , vol.185 , pp. 503-509
    • Appelkvist, E.L.1    Kalén, A.2
  • 67
    • 0023624475 scopus 로고
    • Cholesterol Synthesis in Rat Liver Peroxisomes. Conversion of Mevalonic Acid to Cholesterol
    • Thompson, S.L., Burrows, R., Laub, R.J., and Krisans, S.K. (1987) Cholesterol Synthesis in Rat Liver Peroxisomes. Conversion of Mevalonic Acid to Cholesterol, J. Biol. Chem. 262, 17420-17425.
    • (1987) J. Biol. Chem. , vol.262 , pp. 17420-17425
    • Thompson, S.L.1    Burrows, R.2    Laub, R.J.3    Krisans, S.K.4
  • 68
    • 0027158039 scopus 로고
    • Differential Utilization of Eicosapentaenoic Acid and Docosahexaenoic Acid in Human Plasma
    • Hodge, J., Sanders, K., and Sinclair, A.J. (1993) Differential Utilization of Eicosapentaenoic Acid and Docosahexaenoic Acid in Human Plasma, Lipids 28, 525-531.
    • (1993) Lipids , vol.28 , pp. 525-531
    • Hodge, J.1    Sanders, K.2    Sinclair, A.J.3
  • 69
    • 0025120211 scopus 로고
    • Regulation of the Mevalonate Pathway
    • Goldstein, J.L., and Brown, M.S. (1990) Regulation of the Mevalonate Pathway, Nature 343, 425-430.
    • (1990) Nature , vol.343 , pp. 425-430
    • Goldstein, J.L.1    Brown, M.S.2
  • 70
    • 0023667096 scopus 로고
    • Fish Oil Down Regulates the Low-Density Lipoprotein Receptor and Up-Regulates the High-Density Lipoprotein Receptor of Rat Liver
    • Roach, P.D., Kanbouris, A.M., Trimble, R.P., Topping, D.L., and Nestel, P.J. (1987) Fish Oil Down Regulates the Low-Density Lipoprotein Receptor and Up-Regulates the High-Density Lipoprotein Receptor of Rat Liver, FEBS Lett. 222, 159-162.
    • (1987) FEBS Lett. , vol.222 , pp. 159-162
    • Roach, P.D.1    Kanbouris, A.M.2    Trimble, R.P.3    Topping, D.L.4    Nestel, P.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.