The lymphoma-associated NPM-ALK oncogene elicits a p16INK4a/pRb-dependent tumor-suppressive pathway

Blood

Volumn 117, Issue 24, 2011, Pages 6617-6626

  Martinelli, Paola ^a   Bonetti, Paola ^a   Sironi, Cristina ^a   Pruneri, Giancarlo ^a   Fumagalli, Caterina ^a   Raviele, Paola Rafaniello ^a   Volorio, Sara ^a   Pileri, Stefano ^b   Chiarle, Roberto ^c   McDuff, Fiona Kate Elizabeth ^d   Tusi, Betsabeh Khoramian ^a   Turner, Suzanne D ^d   Inghirami, Giorgio ^c   Pelicci, Pier Giuseppe ^a,e   Colombo, Emanuela ^a,e  

^a EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ARF PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; HISTONE DEMETHYLASE; ONCOPROTEIN; PROTEIN NPM ALK; PROTEIN P53; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CELL AGING; CELL CYCLE ARREST; CONTROLLED STUDY; DEMETHYLATION; DNA DAMAGE; FIBROBLAST; GENE ACTIVATION; GENE MUTATION; HEMATOPOIETIC STEM CELL; LARGE CELL LYMPHOMA; LEUKEMIA; MOUSE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; TRANSCRIPTION REGULATION; TRANSGENIC MOUSE; UPREGULATION;

EID: 79959231353     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-08-301135     Document Type: Article

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