-
1
-
-
0141886877
-
Niemann-Pick disease type C
-
DOI 10.1034/j.1399-0004.2003.00147.x
-
Vanier, M. T., and G. Millat. 2003. Niemann-Pick disease type C. Clin. Genet. 64: 269-281. (Pubitemid 37236127)
-
(2003)
Clinical Genetics
, vol.64
, Issue.4
, pp. 269-281
-
-
Vanier, M.T.1
Millat, G.2
-
2
-
-
77949469173
-
New therapies in the management of Niemann-Pick type C disease: Clinical utility of miglustat
-
Wraith, J. E., and J. Imrie. 2009. New therapies in the management of Niemann-Pick type C disease: clinical utility of miglustat. Ther. Clin. Risk Manag. 5: 877-887.
-
(2009)
Ther. Clin. Risk Manag.
, vol.5
, pp. 877-887
-
-
Wraith, J.E.1
Imrie, J.2
-
3
-
-
0024539791
-
The intracellular transport of low density lipoprotein-derived cholesterol is defective in Niemann-Pick type C fibroblasts
-
Liscum, L., R. M. Ruggiero, and J. R. Faust. 1989. The intracellular transport of low density lipoprotein-derived cholesterol is defective in Niemann-Pick type C fibroblasts. J. Cell Biol. 108: 1625-1636.
-
(1989)
J. Cell Biol.
, vol.108
, pp. 1625-1636
-
-
Liscum, L.1
Ruggiero, R.M.2
Faust, J.R.3
-
4
-
-
0023588096
-
Group c Niemann-Pick disease: Faulty regulation of low-density lipoprotein uptake and cholesterol storage in cultured fibroblasts
-
Pentchev, P. G., M. E. Comly, H. S. Kruth, T. Tokoro, J. Butler, J. Sokol, M. Filling-Katz, J. M. Quirk, D. C. Marshall, and S. Patel. 1987. Group C Niemann-Pick disease: faulty regulation of low-density lipoprotein uptake and cholesterol storage in cultured fibroblasts. FASEB J. 1: 40-45. (Pubitemid 18035324)
-
(1987)
FASEB Journal
, vol.1
, Issue.1
, pp. 40-45
-
-
Pentchev, P.G.1
Comly, M.E.2
Kruth, H.S.3
Tokoro, T.4
Butter, J.5
Sokol, J.6
Filling-Katz, M.7
Quirk, J.M.8
Marshall, D.C.9
Patel, S.10
Vanier, M.T.11
Brady, R.O.12
-
5
-
-
0000721551
-
A defect in cholesterol esterification in Niemann-Pick disease (type C) patients
-
Pentchev, P. G., M. E. Comly, H. S. Kruth, M. T. Vanier, D. A. Wenger, S. Patel, and R. O. Brady. 1985. A defect in cholesterol esterification in Niemann-Pick disease (type C) patients. Proc. Natl. Acad. Sci. USA. 82: 8247-8251.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 8247-8251
-
-
Pentchev, P.G.1
Comly, M.E.2
Kruth, H.S.3
Vanier, M.T.4
Wenger, D.A.5
Patel, S.6
Brady, R.O.7
-
6
-
-
0023850575
-
Type C Niemann-Pick disease. Lysosomal accumulation and defective intracellular mobilization of low density lipoprotein cholesterol
-
Sokol, J., J. Blanchette-Mackie, H. S. Kruth, N. K. Dwyer, L. M. Amende, J. D. Butler, E. Robinson, S. Patel, R. O. Brady, and M. E. Comly. 1988. Type C Niemann-Pick disease. Lysosomal accumulation and defective intracellular mobilization of low density lipoprotein cholesterol. J. Biol. Chem. 263: 3411-3417.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 3411-3417
-
-
Sokol, J.1
Blanchette-Mackie, J.2
Kruth, H.S.3
Dwyer, N.K.4
Amende, L.M.5
Butler, J.D.6
Robinson, E.7
Patel, S.8
Brady, R.O.9
Comly, M.E.10
-
7
-
-
0030863352
-
Niemann-Pick C1 disease gene: Homology to mediators of cholesterol homeostasis
-
DOI 10.1126/science.277.5323.228
-
Carstea, E. D., J. A. Morris, K. G. Coleman, S. K. Loftus, D. Zhang, C. Cummings, J. Gu, M. A. Rosenfeld, W. J. Pavan, D. B. Krizman, et al. 1997. Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis. Science. 277: 228-231. (Pubitemid 27446076)
-
(1997)
Science
, vol.277
, Issue.5323
, pp. 228-231
-
-
Carstea, E.D.1
Morris, J.A.2
Coleman, K.G.3
Loftus, S.K.4
Zhang, D.5
Cummings, C.6
Gu, J.7
Rosenfeld, M.A.8
Pavan, W.J.9
Krizman, D.B.10
Nagle, J.11
Polymeropoulos, M.H.12
Sturley, S.L.13
Ioannou, Y.A.14
Higgins, M.E.15
Comly, M.16
Cooney, A.17
Brown, A.18
Kaneski, C.R.19
Blanchette-Mackie, E.J.20
Dwyer, N.K.21
Neufeld, E.B.22
Chang, T.-Y.23
Liscum, L.24
Strauss III, J.F.25
Ohno, K.26
Zeigler, M.27
Carmi, R.28
Sokol, J.29
Markie, D.30
O'Neill, R.R.31
Van Diggelen, O.P.32
Elleder, M.33
Patterson, M.C.34
Brady, R.O.35
Vanier, M.T.36
Pentchev, P.G.37
Tagle, D.A.38
more..
-
8
-
-
26244438721
-
Niemann-Pick C disease: Use of denaturing high performance liquid chromatography for the detection of NPC1 and NPC2 genetic variations and impact on management of patients and families
-
Millat, G., N. Bailo, S. Molinero, C. Rodriguez, K. Chikh, and M. T. Vanier. 2005. Niemann-Pick C disease: use of denaturing high performance liquid chromatography for the detection of NPC1 and NPC2 genetic variations and impact on management of patients and families. Mol. Genet. Metab. 86: 220-232.
-
(2005)
Mol. Genet. Metab.
, vol.86
, pp. 220-232
-
-
Millat, G.1
Bailo, N.2
Molinero, S.3
Rodriguez, C.4
Chikh, K.5
Vanier, M.T.6
-
9
-
-
0034755958
-
Niemann-Pick disease type C: Spectrum of HE1 mutations and genotype/phenotype correlations in the NPC2 group
-
Millat, G., K. Chikh, S. Naureckiene, D. E. Sleat, A. H. Fensom, K. Higaki, M. Elleder, P. Lobel, and M. T. Vanier. 2001. Niemann-Pick disease type C: spectrum of HE1 mutations and genotype/phenotype correlations in the NPC2 group. Am. J. Hum. Genet. 69: 1013-1021.
-
(2001)
Am. J. Hum. Genet.
, vol.69
, pp. 1013-1021
-
-
Millat, G.1
Chikh, K.2
Naureckiene, S.3
Sleat, D.E.4
Fensom, A.H.5
Higaki, K.6
Elleder, M.7
Lobel, P.8
Vanier, M.T.9
-
10
-
-
0034704245
-
Identification of HE1 as the second gene of Niemann-Pick C disease
-
DOI 10.1126/science.290.5500.2298
-
Naureckiene, S., D. E. Sleat, H. Lackland, A. Fensom, M. T. Vanier, R. Wattiaux, M. Jadot, and P. Lobel. 2000. Identification of HE1 as the second gene of Niemann-Pick C disease. Science. 290: 2298-2301. (Pubitemid 32041569)
-
(2000)
Science
, vol.290
, Issue.5500
, pp. 2298-2301
-
-
Naureckiene, S.1
Sleat, D.E.2
Lacklan, H.3
Fensom, A.4
Vanier, M.T.5
Wattiaux, R.6
Jadot, M.7
Lobel, P.8
-
11
-
-
0034635356
-
Role of Niemann-Pick type C1 protein in intracellular trafficking of low density lipoprotein-derived cholesterol
-
Cruz, J. C., S. Sugii, C. Yu, and T. Y. Chang. 2000. Role of Niemann-Pick type C1 protein in intracellular trafficking of low density lipoprotein-derived cholesterol. J. Biol. Chem. 275: 4013-4021.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 4013-4021
-
-
Cruz, J.C.1
Sugii, S.2
Yu, C.3
Chang, T.Y.4
-
12
-
-
67549105629
-
Structure of N-terminal domain of NPC1 reveals distinct subdomains for binding and transfer of cholesterol
-
Kwon, H. J., L. Abi-Mosleh, M. L. Wang, J. Deisenhofer, J. L. Goldstein, M. S. Brown, and R. E. Infante. 2009. Structure of N-terminal domain of NPC1 reveals distinct subdomains for binding and transfer of cholesterol. Cell. 137: 1213-1224.
-
(2009)
Cell
, vol.137
, pp. 1213-1224
-
-
Kwon, H.J.1
Abi-Mosleh, L.2
Wang, M.L.3
Deisenhofer, J.4
Goldstein, J.L.5
Brown, M.S.6
Infante, R.E.7
-
13
-
-
0027976761
-
The Niemann-Pick C lesion and its relationship to the intracellular distribution and utilization of LDL cholesterol
-
Pentchev, P. G., R. O. Brady, E. J. Blanchette-Mackie, M. T. Vanier, E. D. Carstea, C. C. Parker, E. Goldin, and C. F. Roff. 1994. The Niemann-Pick C lesion and its relationship to the intracellular distribution and utilization of LDL cholesterol. Biochim. Biophys. Acta. 1225: 235-243.
-
(1994)
Biochim. Biophys. Acta.
, vol.1225
, pp. 235-243
-
-
Pentchev, P.G.1
Brady, R.O.2
Blanchette-Mackie, E.J.3
Vanier, M.T.4
Carstea, E.D.5
Parker, C.C.6
Goldin, E.7
Roff, C.F.8
-
14
-
-
0035940491
-
Accumulation of cholera toxin and GM1 ganglioside in the early endosome of niemann-pick C1-deficient cells
-
DOI 10.1073/pnas.221181998
-
Sugimoto, Y., H. Ninomiya, Y. Ohsaki, K. Higaki, J. P. Davies, Y. A. Ioannou, and K. Ohno. 2001. Accumulation of cholera toxin and GM1 ganglioside in the early endosome of Niemann-Pick C1-deficient cells. Proc. Natl. Acad. Sci. USA. 98: 12391-12396. (Pubitemid 33019956)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.22
, pp. 12391-12396
-
-
Sugimoto, Y.1
Ninomiya, H.2
Ohsaki, Y.3
Higaki, K.4
Davies, J.P.5
Ioannou, Y.A.6
Ohno, K.7
-
15
-
-
0035793562
-
Sterol-modulated glycolipid sorting occurs in niemann-pick C1 late endosomes
-
Zhang, M., N. K. Dwyer, E. B. Neufeld, D. C. Love, A. Cooney, M. Comly, S. Patel, H. Watari, J. F. Strauss 3rd, P. G. Pentchev, et al. 2001. Sterol-modulated glycolipid sorting occurs in niemann-pick C1 late endosomes. J. Biol. Chem. 276: 3417-3425.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3417-3425
-
-
Zhang, M.1
Dwyer, N.K.2
Neufeld, E.B.3
Love, D.C.4
Cooney, A.5
Comly, M.6
Patel, S.7
Watari, H.8
Strauss III, J.F.9
Pentchev, P.G.10
-
16
-
-
48549102737
-
Neuronal loss of Drosophila NPC1a causes cholesterol aggregation and age-progressive neurodegeneration
-
Phillips, S. E., E. A. Woodruff 3rd, P. Liang, M. Patten, and K. Broadie. 2008. Neuronal loss of Drosophila NPC1a causes cholesterol aggregation and age-progressive neurodegeneration. J. Neurosci. 28: 6569-6582.
-
(2008)
J. Neurosci.
, vol.28
, pp. 6569-6582
-
-
Phillips, S.E.1
Woodruff III, E.A.2
Liang, P.3
Patten, M.4
Broadie, K.5
-
17
-
-
0038158091
-
The transport of low density lipoprotein-derived cholesterol to the plasma membrane is defective in NPC1 cells
-
DOI 10.1074/jbc.M300488200
-
Wojtanik, K. M., and L. Liscum. 2003. The transport of low density lipoprotein-derived cholesterol to the plasma membrane is defective in NPC1 cells. J. Biol. Chem. 278: 14850-14856. (Pubitemid 36799812)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.17
, pp. 14850-14856
-
-
Wojtanik, K.M.1
Liscum, L.2
-
18
-
-
0030768084
-
Murine model of Niemann-Pick C disease: Mutation in a cholesterol homeostasis gene
-
DOI 10.1126/science.277.5323.232
-
Loftus, S. K., J. A. Morris, E. D. Carstea, J. Z. Gu, C. Cummings, A. Brown, J. Ellison, K. Ohno, M. A. Rosenfeld, D. A. Tagle, et al. 1997. Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene. Science. 277: 232-235. (Pubitemid 27446077)
-
(1997)
Science
, vol.277
, Issue.5323
, pp. 232-235
-
-
Loftus, S.K.1
Morris, J.A.2
Carstea, E.D.3
Gu, J.Z.4
Cummings, C.5
Brown, A.6
Ellison, J.7
Ohno, K.8
Rosenfeld, M.A.9
Tagle, D.A.10
Pentchev, P.G.11
Pavan, W.J.12
-
19
-
-
0031742639
-
Niemann-Pick C disease: Cholesterol handling gone awry
-
Morris, J. A., and E. D. Carstea. 1998. Niemann-Pick C disease: cholesterol handling gone awry. Mol. Med. Today. 4: 525-531.
-
(1998)
Mol. Med. Today.
, vol.4
, pp. 525-531
-
-
Morris, J.A.1
Carstea, E.D.2
-
20
-
-
0035142802
-
Neurons in Niemann-Pick disease type C accumulate gangliosides as well as unesterified cholesterol and undergo dendritic and axonal alterations
-
Zervas, M., K. Dobrenis, and S. U. Walkley. 2001. Neurons in Niemann-Pick disease type C accumulate gangliosides as well as unesterified cholesterol and undergo dendritic and axonal alterations. J. Neuropathol. Exp. Neurol. 60: 49-64.
-
(2001)
J. Neuropathol. Exp. Neurol.
, vol.60
, pp. 49-64
-
-
Zervas, M.1
Dobrenis, K.2
Walkley, S.U.3
-
21
-
-
3142774112
-
Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone
-
Griffin, L. D., W. Gong, L. Verot, and S. H. Mellon. 2004. Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone. Nat. Med. 10: 704-711.
-
(2004)
Nat. Med.
, vol.10
, pp. 704-711
-
-
Griffin, L.D.1
Gong, W.2
Verot, L.3
Mellon, S.H.4
-
22
-
-
36148978574
-
Drosophila Niemann-Pick type C-2 genes control sterol homeostasis and steroid biosynthesis: A model of human neurodegenerative disease
-
Huang, X., J. T. Warren, J. Buchanan, L. I. Gilbert, and M. P. Scott. 2007. Drosophila Niemann-Pick type C-2 genes control sterol homeostasis and steroid biosynthesis: a model of human neurodegenerative disease. Development. 134: 3733-3742.
-
(2007)
Development
, vol.134
, pp. 3733-3742
-
-
Huang, X.1
Warren, J.T.2
Buchanan, J.3
Gilbert, L.I.4
Scott, M.P.5
-
23
-
-
28844473468
-
A Drosophila model of the Niemann-Pick type C lysosome storage disease: Dnpc1a is required for molting and sterol homeostasis
-
Huang, X., K. Suyama, J. Buchanan, A. J. Zhu, and M. P. Scott. 2005. A Drosophila model of the Niemann-Pick type C lysosome storage disease: dnpc1a is required for molting and sterol homeostasis. Development. 132: 5115-5124.
-
(2005)
Development
, vol.132
, pp. 5115-5124
-
-
Huang, X.1
Suyama, K.2
Buchanan, J.3
Zhu, A.J.4
Scott, M.P.5
-
24
-
-
0024064517
-
Molecular biology of steroid hormone synthesis
-
Miller, W. L. 1988. Molecular biology of steroid hormone synthesis. Endocr. Rev. 9: 295-318.
-
(1988)
Endocr. Rev.
, vol.9
, pp. 295-318
-
-
Miller, W.L.1
-
25
-
-
0031024456
-
Transcriptional regulation of the CYP11A1 and ferredoxin genes
-
Chung, B. C., I. C. Guo, and S. J. Chou. 1997. Transcriptional regulation of the CYP11A1 and ferredoxin genes. Steroids. 62: 37-42.
-
(1997)
Steroids
, vol.62
, pp. 37-42
-
-
Chung, B.C.1
Guo, I.C.2
Chou, S.J.3
-
26
-
-
33644764857
-
Mutations of a Drosophila NPC1 gene confer sterol and ecdysone metabolic defects
-
Fluegel, M. L., T. J. Parker, and L. J. Pallanck. 2006. Mutations of a Drosophila NPC1 gene confer sterol and ecdysone metabolic defects. Genetics. 172: 185-196.
-
(2006)
Genetics
, vol.172
, pp. 185-196
-
-
Fluegel, M.L.1
Parker, T.J.2
Pallanck, L.J.3
-
27
-
-
40749148475
-
Endogenous and synthetic neurosteroids in treatment of Niemann-Pick Type C disease
-
Mellon, S. H., W. Gong, and M. D. Schonemann. 2008. Endogenous and synthetic neurosteroids in treatment of Niemann-Pick Type C disease. Brain Res. Rev. 57: 410-420.
-
(2008)
Brain Res. Rev.
, vol.57
, pp. 410-420
-
-
Mellon, S.H.1
Gong, W.2
Schonemann, M.D.3
-
28
-
-
71549134227
-
Oxidative stress in NPC1 deficient cells: Protective effect of allopregnanolone
-
Zampieri, S., S. H. Mellon, T. D. Butters, M. Nevyjel, D. F. Covey, B. Bembi, and A. Dardis. 2009. Oxidative stress in NPC1 deficient cells: protective effect of allopregnanolone. J. Cell. Mol. Med. 13: 3786-3796.
-
(2009)
J. Cell. Mol. Med.
, vol.13
, pp. 3786-3796
-
-
Zampieri, S.1
Mellon, S.H.2
Butters, T.D.3
Nevyjel, M.4
Covey, D.F.5
Bembi, B.6
Dardis, A.7
-
29
-
-
71849085133
-
Female infertility due to anovulation and defective steroidogenesis in NPC2 deficient mice
-
Busso, D., M. J. Onate-Alvarado, E. Balboa, S. Zanlungo, and R. D. Moreno. 2010. Female infertility due to anovulation and defective steroidogenesis in NPC2 deficient mice. Mol. Cell. Endocrinol. 315: 299-307.
-
(2010)
Mol. Cell. Endocrinol.
, vol.315
, pp. 299-307
-
-
Busso, D.1
Onate-Alvarado, M.J.2
Balboa, E.3
Zanlungo, S.4
Moreno, R.D.5
-
30
-
-
3042711799
-
Aberrant intracellular cholesterol transport disrupts pituitary and ovarian function
-
Gevry, N. Y., F. L. Lopes, S. Ledoux, and B. D. Murphy. 2004. Aberrant intracellular cholesterol transport disrupts pituitary and ovarian function. Mol. Endocrinol. 18: 1778-1786.
-
(2004)
Mol. Endocrinol.
, vol.18
, pp. 1778-1786
-
-
Gevry, N.Y.1
Lopes, F.L.2
Ledoux, S.3
Murphy, B.D.4
-
32
-
-
0034637440
-
Topological analysis of Niemann-Pick C1 protein reveals that the membrane orientation of the putative sterol-sensing domain is identical to those of 3-hydroxy-3-methylglutaryl-CoA reductase and sterol regulatory element binding protein cleavage-activating protein
-
Davies, J. P., and Y. A. Ioannou. 2000. Topological analysis of Niemann-Pick C1 protein reveals that the membrane orientation of the putative sterol-sensing domain is identical to those of 3-hydroxy-3-methylglutaryl-CoA reductase and sterol regulatory element binding protein cleavage-activating protein. J. Biol. Chem. 275: 24367-24374.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 24367-24374
-
-
Davies, J.P.1
Ioannou, Y.A.2
-
33
-
-
0036534286
-
The sterol-sensing domain: Multiple families, a unique role?
-
DOI 10.1016/S0168-9525(02)02640-9, PII S0168952502026409
-
Kuwabara, P. E., and M. Labouesse. 2002. The sterol-sensing domain: multiple families, a unique role? Trends Genet. 18: 193-201. (Pubitemid 34273740)
-
(2002)
Trends in Genetics
, vol.18
, Issue.4
, pp. 193-201
-
-
Kuwabara, P.E.1
Labouesse, M.2
-
34
-
-
73049111644
-
Zebrafish con/disp1 reveals multiple spatiotemporal requirements for Hedgehog-signaling in craniofacial development
-
Schwend, T., and S. C. Ahlgren. 2009. Zebrafish con/disp1 reveals multiple spatiotemporal requirements for Hedgehog-signaling in craniofacial development. BMC Dev. Biol. 9: 59.
-
(2009)
BMC Dev. Biol.
, vol.9
, pp. 59
-
-
Schwend, T.1
Ahlgren, S.C.2
-
35
-
-
77954712606
-
Zebrafish: Gaining popularity in lipid research
-
Holtta-Vuori, M., V. T. Salo, L. Nyberg, C. Brackmann, A. Enejder, P. Panula, and E. Ikonen. 2010. Zebrafish: gaining popularity in lipid research. Biochem. J. 429: 235-242.
-
(2010)
Biochem. J.
, vol.429
, pp. 235-242
-
-
Holtta-Vuori, M.1
Salo, V.T.2
Nyberg, L.3
Brackmann, C.4
Enejder, A.5
Panula, P.6
Ikonen, E.7
-
36
-
-
0036946974
-
Expression of zebrafish cyp11a1 as a maternal transcript and in yolk syncytial layer
-
Hsu, H. J., P. Hsiao, M. W. Kuo, and B. C. Chung. 2002. Expression of zebrafish cyp11a1 as a maternal transcript and in yolk syncytial layer. Gene Expr. Patterns. 2: 219-222.
-
(2002)
Gene Expr. Patterns
, vol.2
, pp. 219-222
-
-
Hsu, H.J.1
Hsiao, P.2
Kuo, M.W.3
Chung, B.C.4
-
37
-
-
31444453266
-
Pregnenolone stabilizes microtubules and promotes zebrafish embryonic cell movement
-
Hsu, H. J., M. R. Liang, C. T. Chen, and B. C. Chung. 2006. Pregnenolone stabilizes microtubules and promotes zebrafish embryonic cell movement. Nature. 439: 480-483.
-
(2006)
Nature
, vol.439
, pp. 480-483
-
-
Hsu, H.J.1
Liang, M.R.2
Chen, C.T.3
Chung, B.C.4
-
38
-
-
84981833876
-
A study of the mechanism of epiboly in the egg of Fundulus heteroclitus
-
Trinkaus, J. 1951. A study of the mechanism of epiboly in the egg of Fundulus heteroclitus. J. Exp. Zool. 118: 269-319.
-
(1951)
J. Exp. Zool.
, vol.118
, pp. 269-319
-
-
Trinkaus, J.1
-
39
-
-
0027497194
-
Ultraviolet irradiation impairs epiboly in zebrafish embryos: Evidence for a microtubule-dependent mechanism of epiboly
-
Strahle, U., and S. Jesuthasan. 1993. Ultraviolet irradiation impairs epiboly in zebrafish embryos: evidence for a microtubule-dependent mechanism of epiboly. Development. 119: 909-919. (Pubitemid 23337430)
-
(1993)
Development
, vol.119
, Issue.3
, pp. 909-919
-
-
Strahle, U.1
Jesuthasan, S.2
-
40
-
-
33745611527
-
Gastrulation in zebrafish-all just about adhesion?
-
Solnica-Krezel, L. 2006. Gastrulation in zebrafish-all just about adhesion? Curr. Opin. Genet. Dev. 16: 433-441.
-
(2006)
Curr. Opin. Genet. Dev.
, vol.16
, pp. 433-441
-
-
Solnica-Krezel, L.1
-
41
-
-
34249778979
-
Zebrafish gastrulation: Cell movements, signals, and mechanisms
-
Rohde, L. A., and C. P. Heisenberg. 2007. Zebrafish gastrulation: cell movements, signals, and mechanisms. Int. Rev. Cytol. 261: 159-192.
-
(2007)
Int. Rev. Cytol.
, vol.261
, pp. 159-192
-
-
Rohde, L.A.1
Heisenberg, C.P.2
-
42
-
-
0025269196
-
Cell movements during epiboly and gastrulation in zebrafish
-
Warga, R. M., and C. B. Kimmel. 1990. Cell movements during epiboly and gastrulation in zebrafish. Development. 108: 569-580.
-
(1990)
Development
, vol.108
, pp. 569-580
-
-
Warga, R.M.1
Kimmel, C.B.2
-
43
-
-
63449097615
-
A novel role for MAPKAPK2 in morphogenesis during zebrafish development
-
Holloway, B. A., S. Gomez de la Torre Canny, Y. Ye, D. C. Slusarski, C. M. Freisinger, R. Dosch, M. M. Chou, D. S. Wagner, and M. C. Mullins. 2009. A novel role for MAPKAPK2 in morphogenesis during zebrafish development. PLoS Genet. 5: e1000413.
-
(2009)
PLoS Genet.
, vol.5
-
-
Holloway, B.A.1
Gomez De La Torre Canny, S.2
Ye, Y.3
Slusarski, D.C.4
Freisinger, C.M.5
Dosch, R.6
Chou, M.M.7
Wagner, D.S.8
Mullins, M.C.9
-
44
-
-
15744401970
-
Conserved patterns of cell movements during vertebrate gastrulation
-
DOI 10.1016/j.cub.2005.03.016
-
Solnica-Krezel, L. 2005. Conserved patterns of cell movements during vertebrate gastrulation. Curr. Biol. 15: R213-R228. (Pubitemid 40413386)
-
(2005)
Current Biology
, vol.15
, Issue.6
-
-
Solnica-Krezel, L.1
-
45
-
-
77956872754
-
Poky/chuk/ikk1 is required for differentiation of the zebrafish embryonic epidermis
-
Fukazawa, C., C. Santiago, K. M. Park, W. J. Deery, S. Gomez de la Torre Canny, C. K. Holterhoff, and D. S. Wagner. 2010. Poky/chuk/ikk1 is required for differentiation of the zebrafish embryonic epidermis. Dev. Biol. 346: 272-283.
-
(2010)
Dev. Biol.
, vol.346
, pp. 272-283
-
-
Fukazawa, C.1
Santiago, C.2
Park, K.M.3
Deery, W.J.4
Gomez De La Torre Canny, S.5
Holterhoff, C.K.6
Wagner, D.S.7
-
46
-
-
57849091769
-
Maternal interferon regulatory factor 6 is required for the differentiation of primary superficial epithelia in Danio and Xenopus embryos
-
Sabel, J. L., C. d'Alencon, E. K. O'Brien, E. Van Otterloo, K. Lutz, T. N. Cuykendall, B. C. Schutte, D. W. Houston, and R. A. Cornell. 2009. Maternal interferon regulatory factor 6 is required for the differentiation of primary superficial epithelia in Danio and Xenopus embryos. Dev. Biol. 325: 249-262.
-
(2009)
Dev. Biol.
, vol.325
, pp. 249-262
-
-
Sabel, J.L.1
D'alencon, C.2
O'Brien, E.K.3
Van Otterloo, E.4
Lutz, K.5
Cuykendall, T.N.6
Schutte, B.C.7
Houston, D.W.8
Cornell, R.A.9
-
47
-
-
33746861920
-
Coordinated cell-shape changes control epithelial movement in zebrafish and Drosophila
-
Koppen, M., B. G. Fernandez, L. Carvalho, A. Jacinto, and C. P. Heisenberg. 2006. Coordinated cell-shape changes control epithelial movement in zebrafish and Drosophila. Development. 133: 2671-2681.
-
(2006)
Development
, vol.133
, pp. 2671-2681
-
-
Koppen, M.1
Fernandez, B.G.2
Carvalho, L.3
Jacinto, A.4
Heisenberg, C.P.5
-
48
-
-
0029045033
-
Stages of embryonic development of the zebrafish
-
Kimmel, C. B., W. W. Ballard, S. R. Kimmel, B. Ullmann, and T. F. Schilling. 1995. Stages of embryonic development of the zebrafish. Dev. Dyn. 203: 253-310.
-
(1995)
Dev. Dyn.
, vol.203
, pp. 253-310
-
-
Kimmel, C.B.1
Ballard, W.W.2
Kimmel, S.R.3
Ullmann, B.4
Schilling, T.F.5
-
50
-
-
34249680274
-
P53 activation by knockdown technologies
-
Robu, M. E., J. D. Larson, A. Nasevicius, S. Beiraghi, C. Brenner, S. A. Farber, and S. C. Ekker. 2007. P53 activation by knockdown technologies. PLoS Genet. 3: e78.
-
(2007)
PLoS Genet.
, vol.3
-
-
Robu, M.E.1
Larson, J.D.2
Nasevicius, A.3
Beiraghi, S.4
Brenner, C.5
Farber, S.A.6
Ekker, S.C.7
-
51
-
-
0027453569
-
Structure of the zebrafish snail1 gene and its expression in wildtype, spadetail and no tail mutant embryos
-
Thisse, C., B. Thisse, T. F. Schilling, and J. H. Postlethwait. 1993. Structure of the zebrafish snail1 gene and its expression in wildtype, spadetail and no tail mutant embryos. Development. 119: 1203-1215.
-
(1993)
Development
, vol.119
, pp. 1203-1215
-
-
Thisse, C.1
Thisse, B.2
Schilling, T.F.3
Postlethwait, J.H.4
-
53
-
-
0028344796
-
no tail (ntl) is the zebrafish homologue of the mouse T (Brachyury) gene
-
Schulte-Merker, S., F. J. van Eeden, M. E. Halpern, C. B. Kimmel, and C. Nusslein-Volhard. 1994. no tail (ntl) is the zebrafish homologue of the mouse T (Brachyury) gene. Development. 120: 1009-1015. (Pubitemid 24111563)
-
(1994)
Development
, vol.120
, Issue.4
, pp. 1009-1015
-
-
Schulte-Merker, S.1
Van Eeden, F.J.M.2
Halpern, M.E.3
Kimmel, C.B.4
Nusslein-Volhard, C.5
-
55
-
-
0031697445
-
Zebrafish paraxial protocadherin is a downstream target of spadetail involved in morphogenesis of gastrula mesoderm
-
Yamamoto, A., S. L. Amacher, S. H. Kim, D. Geissert, C. B. Kimmel, and E. M. De Robertis. 1998. Zebrafish paraxial protocadherin is a downstream target of spadetail involved in morphogenesis of gastrula mesoderm. Development. 125: 3389-3397.
-
(1998)
Development
, vol.125
, pp. 3389-3397
-
-
Yamamoto, A.1
Amacher, S.L.2
Kim, S.H.3
Geissert, D.4
Kimmel, C.B.5
De Robertis, E.M.6
-
56
-
-
0345020436
-
Ethanol impairs migration of the prechordal plate in the zebrafish embryo
-
DOI 10.1006/dbio.1998.8995
-
Blader, P., and U. Strahle. 1998. Ethanol impairs migration of the prechordal plate in the zebrafish embryo. Dev. Biol. 201: 185-201. (Pubitemid 28447213)
-
(1998)
Developmental Biology
, vol.201
, Issue.2
, pp. 185-201
-
-
Blader, P.1
Strahle, U.2
-
57
-
-
0346840376
-
-
Direct Data Submission
-
Thisse, B., S. Pflumio, M. Fürthauer, B. Loppin, V. Heyer, A. Degrave, R. Woehl, A. Lux, T. Steffan, X. Charbonnier, et al. 2001. Expression of the zebrafish genome during embryogenesis (NIH R01-RR15402). ZFIN Direct Data Submission (http://zfin.org).
-
(2001)
Expression of the Zebrafish Genome during Embryogenesis (NIH R01-RR15402)
-
-
Thisse, B.1
Pflumio, S.2
Fürthauer, M.3
Loppin, B.4
Heyer, V.5
Degrave, A.6
Woehl, R.7
Lux, A.8
Steffan, T.9
Charbonnier, X.10
-
58
-
-
33344459100
-
Spatiotemporal expression of zebrafish keratin 18 during early embryogenesis and the establishment of a keratin 18:RFP transgenic line
-
Wang, Y. H., Y. H. Chen, Y. J. Lin, and H. J. Tsai. 2006. Spatiotemporal expression of zebrafish keratin 18 during early embryogenesis and the establishment of a keratin 18:RFP transgenic line. Gene Expr. Patterns. 6: 335-339.
-
(2006)
Gene Expr. Patterns
, vol.6
, pp. 335-339
-
-
Wang, Y.H.1
Chen, Y.H.2
Lin, Y.J.3
Tsai, H.J.4
-
59
-
-
77951936055
-
The tight junction component Claudin e is required for zebrafish epiboly
-
Siddiqui, M., H. Sheikh, C. Tran, and A. E. Bruce. 2010. The tight junction component Claudin E is required for zebrafish epiboly. Dev. Dyn. 239: 715-722.
-
(2010)
Dev. Dyn.
, vol.239
, pp. 715-722
-
-
Siddiqui, M.1
Sheikh, H.2
Tran, C.3
Bruce, A.E.4
-
60
-
-
34648844185
-
An early requirement for maternal FoxH1 during zebrafish gastrulation
-
DOI 10.1016/j.ydbio.2007.07.011, PII S0012160607011864
-
Pei, W., H. Noushmehr, J. Costa, M. V. Ouspenskaia, A. G. Elkahloun, and B. Feldman. 2007. An early requirement for maternal FoxH1 during zebrafish gastrulation. Dev. Biol. 310: 10-22. (Pubitemid 47454606)
-
(2007)
Developmental Biology
, vol.310
, Issue.1
, pp. 10-22
-
-
Pei, W.1
Noushmehr, H.2
Costa, J.3
Ouspenskaia, M.V.4
Elkahloun, A.G.5
Feldman, B.6
-
61
-
-
0031238445
-
Expression de la cytokeratine 8 au cours du developpement du poisson zebre
-
DOI 10.1016/S0764-4469(97)84816-0
-
Imboden, M., C. Goblet, H. Korn, and S. Vriz. 1997. Cytokeratin 8 is a suitable epidermal marker during zebrafish development. C. R. Acad. Sci. III. 320: 689-700. (Pubitemid 27469736)
-
(1997)
Comptes Rendus de l'Academie des Sciences - Serie III
, vol.320
, Issue.9
, pp. 689-700
-
-
Imboden, M.1
Goblet, C.2
Korn, H.3
Vriz, S.4
-
62
-
-
33645554622
-
Retinoids signal directly to zebrafish endoderm to specify insulin-expressing beta-cells
-
Stafford, D., R. J. White, M. D. Kinkel, A. Linville, T. F. Schilling, and V. E. Prince. 2006. Retinoids signal directly to zebrafish endoderm to specify insulin-expressing beta-cells. Development. 133: 949-956.
-
(2006)
Development
, vol.133
, pp. 949-956
-
-
Stafford, D.1
White, R.J.2
Kinkel, M.D.3
Linville, A.4
Schilling, T.F.5
Prince, V.E.6
-
63
-
-
4544363682
-
Organization and function of microfilaments during late epiboly in zebrafish embryos
-
Cheng, J. C., A. L. Miller, and S. E. Webb. 2004. Organization and function of microfilaments during late epiboly in zebrafish embryos. Dev. Dyn. 231: 313-323.
-
(2004)
Dev. Dyn.
, vol.231
, pp. 313-323
-
-
Cheng, J.C.1
Miller, A.L.2
Webb, S.E.3
-
64
-
-
0033813196
-
The structure and function of the Niemann-Pick C1 protein
-
Ioannou, Y. A. 2000. The structure and function of the Niemann-Pick C1 protein. Mol. Genet. Metab. 71: 175-181.
-
(2000)
Mol. Genet. Metab.
, vol.71
, pp. 175-181
-
-
Ioannou, Y.A.1
-
65
-
-
23344445128
-
The sterol-sensing domain of the Niemann-Pick C1 (NPC1) protein regulates trafficking of low density lipoprotein cholesterol
-
Millard, E. E., S. E. Gale, N. Dudley, J. Zhang, J. E. Schaffer, and D. S. Ory. 2005. The sterol-sensing domain of the Niemann-Pick C1 (NPC1) protein regulates trafficking of low density lipoprotein cholesterol. J. Biol. Chem. 280: 28581-28590.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 28581-28590
-
-
Millard, E.E.1
Gale, S.E.2
Dudley, N.3
Zhang, J.4
Schaffer, J.E.5
Ory, D.S.6
-
66
-
-
4344637102
-
Binding between the Niemann-Pick C1 protein and a photoactivatable cholesterol analog requires a functional sterolsensing domain
-
Ohgami, N., D. C. Ko, M. Thomas, M. P. Scott, C. C. Chang, and T. Y. Chang. 2004. Binding between the Niemann-Pick C1 protein and a photoactivatable cholesterol analog requires a functional sterolsensing domain. Proc. Natl. Acad. Sci. USA. 101: 12473-12478.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 12473-12478
-
-
Ohgami, N.1
Ko, D.C.2
Thomas, M.3
Scott, M.P.4
Chang, C.C.5
Chang, T.Y.6
-
67
-
-
0032887393
-
Niemann-Pick C1 is a late endosome-resident protein that transiently associates with lysosomes and the trans-Golgi network
-
Higgins, M. E., J. P. Davies, F. W. Chen, and Y. A. Ioannou. 1999. Niemann-Pick C1 is a late endosome-resident protein that transiently associates with lysosomes and the trans-Golgi network. Mol. Genet. Metab. 68: 1-13.
-
(1999)
Mol. Genet. Metab.
, vol.68
, pp. 1-13
-
-
Higgins, M.E.1
Davies, J.P.2
Chen, F.W.3
Ioannou, Y.A.4
-
68
-
-
0033515560
-
The Niemann-Pick C1 protein resides in a vesicular compartment linked to retrograde transport of multiple lysosomal cargo
-
Neufeld, E. B., M. Wastney, S. Patel, S. Suresh, A. M. Cooney, N. K. Dwyer, C. F. Roff, K. Ohno, J. A. Morris, E. D. Carstea, et al. 1999. The Niemann-Pick C1 protein resides in a vesicular compartment linked to retrograde transport of multiple lysosomal cargo. J. Biol. Chem. 274: 9627-9635.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 9627-9635
-
-
Neufeld, E.B.1
Wastney, M.2
Patel, S.3
Suresh, S.4
Cooney, A.M.5
Dwyer, N.K.6
Roff, C.F.7
Ohno, K.8
Morris, J.A.9
Carstea, E.D.10
-
69
-
-
0019795691
-
Beta-Hydroxysterol distribution as determined by freeze-fracture cytochemistry
-
Friend, D. S., and E. L. Bearer. 1981. beta-Hydroxysterol distribution as determined by freeze-fracture cytochemistry. Histochem. J. 13: 535-546.
-
(1981)
Histochem. J.
, vol.13
, pp. 535-546
-
-
Friend, D.S.1
Bearer, E.L.2
-
70
-
-
0041700117
-
Cholesterol accumulation in NPC1-deficient neurons is ganglioside dependent
-
Gondre-Lewis, M. C., R. McGlynn, and S. U. Walkley. 2003. Cholesterol accumulation in NPC1-deficient neurons is ganglioside dependent. Curr. Biol. 13: 1324-1329.
-
(2003)
Curr. Biol.
, vol.13
, pp. 1324-1329
-
-
Gondre-Lewis, M.C.1
McGlynn, R.2
Walkley, S.U.3
-
71
-
-
0033694706
-
The role of the yolk syncytial layer in germ layer patterning in zebrafish
-
Chen, S., and D. Kimelman. 2000. The role of the yolk syncytial layer in germ layer patterning in zebrafish. Development. 127: 4681-4689.
-
(2000)
Development
, vol.127
, pp. 4681-4689
-
-
Chen, S.1
Kimelman, D.2
-
72
-
-
64549131800
-
Flamingo regulates epiboly and convergence/extension movements through cell cohesive and signalling functions during zebrafish gastrulation
-
Carreira-Barbosa, F., M. Kajita, V. Morel, H. Wada, H. Okamoto, A. Martinez Arias, Y. Fujita, S. W. Wilson, and M. Tada. 2009. Flamingo regulates epiboly and convergence/extension movements through cell cohesive and signalling functions during zebrafish gastrulation. Development. 136: 383-392.
-
(2009)
Development
, vol.136
, pp. 383-392
-
-
Carreira-Barbosa, F.1
Kajita, M.2
Morel, V.3
Wada, H.4
Okamoto, H.5
Martinez Arias, A.6
Fujita, Y.7
Wilson, S.W.8
Tada, M.9
-
73
-
-
0034012322
-
Autophagic and apoptotic types of programmed cell death exhibit different fates of cytoskeletal filaments
-
Bursch, W., K. Hochegger, L. Torok, B. Marian, A. Ellinger, and R. S. Hermann. 2000. Autophagic and apoptotic types of programmed cell death exhibit different fates of cytoskeletal filaments. J. Cell Sci. 113: 1189-1198.
-
(2000)
J. Cell Sci.
, vol.113
, pp. 1189-1198
-
-
Bursch, W.1
Hochegger, K.2
Torok, L.3
Marian, B.4
Ellinger, A.5
Hermann, R.S.6
-
74
-
-
38049073134
-
Genetic interactions between Drosophila melanogaster Atg1 and paxillin reveal a role for paxillin in autophagosome formation
-
Chen, G. C., J. Y. Lee, H. W. Tang, J. Debnath, S. M. Thomas, and J. Settleman. 2008. Genetic interactions between Drosophila melanogaster Atg1 and paxillin reveal a role for paxillin in autophagosome formation. Autophagy. 4: 37-45.
-
(2008)
Autophagy
, vol.4
, pp. 37-45
-
-
Chen, G.C.1
Lee, J.Y.2
Tang, H.W.3
Debnath, J.4
Thomas, S.M.5
Settleman, J.6
-
75
-
-
0345160562
-
Human cholesterol side-chain cleavage enzyme, P450scc: CDNA cloning, assignment of the gene to chromosome 15, and expression in the placenta
-
Chung, B. C., K. J. Matteson, R. Voutilainen, T. K. Mohandas, and W. L. Miller. 1986. Human cholesterol side-chain cleavage enzyme, P450scc: cDNA cloning, assignment of the gene to chromosome 15, and expression in the placenta. Proc. Natl. Acad. Sci. USA. 83: 8962-8966.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 8962-8966
-
-
Chung, B.C.1
Matteson, K.J.2
Voutilainen, R.3
Mohandas, T.K.4
Miller, W.L.5
-
76
-
-
33644911733
-
Steroidogenesis in zebrafish and mouse models
-
Hsu, H. J., N. C. Hsu, M. C. Hu, and B. C. Chung. 2006. Steroidogenesis in zebrafish and mouse models. Mol. Cell. Endocrinol. 248: 160-163.
-
(2006)
Mol. Cell. Endocrinol.
, vol.248
, pp. 160-163
-
-
Hsu, H.J.1
Hsu, N.C.2
Hu, M.C.3
Chung, B.C.4
-
78
-
-
34247402098
-
Glucocorticoids play a key role in circadian cell cycle rhythms
-
Dickmeis, T., K. Lahiri, G. Nica, D. Vallone, C. Santoriello, C. J. Neumann, M. Hammerschmidt, and N. S. Foulkes. 2007. Glucocorticoids play a key role in circadian cell cycle rhythms. PLoS Biol. 5: e78.
-
(2007)
PLoS Biol.
, vol.5
-
-
Dickmeis, T.1
Lahiri, K.2
Nica, G.3
Vallone, D.4
Santoriello, C.5
Neumann, C.J.6
Hammerschmidt, M.7
Foulkes, N.S.8
-
79
-
-
40949102164
-
Glucocorticoids alter craniofacial development and increase expression and activity of matrix metalloproteinases in developing zebrafish (Danio rerio)
-
Hillegass, J. M., C. M. Villano, K. R. Cooper, and L. A. White. 2008. Glucocorticoids alter craniofacial development and increase expression and activity of matrix metalloproteinases in developing zebrafish (Danio rerio). Toxicol. Sci. 102: 413-424.
-
(2008)
Toxicol. Sci.
, vol.102
, pp. 413-424
-
-
Hillegass, J.M.1
Villano, C.M.2
Cooper, K.R.3
White, L.A.4
-
80
-
-
0031763014
-
Hormone-inducible expression of secreted factors in zebrafish embryos
-
DOI 10.1046/j.1440-169x.1998.00396.x
-
de Graaf, M., D. Zivkovic, and J. Joore. 1998. Hormone-inducible expression of secreted factors in zebrafish embryos. Dev. Growth Differ. 40: 577-582. (Pubitemid 28555305)
-
(1998)
Development Growth and Differentiation
, vol.40
, Issue.6
, pp. 577-582
-
-
De Graaf, M.1
Zivkovic, D.2
Joore, J.3
-
81
-
-
12644273790
-
Neural degeneration mutants in the zebrafish, Danio rerio
-
Furutani-Seiki, M., Y. J. Jiang, M. Brand, C. P. Heisenberg, C. Houart, D. Beuchle, F. J. van Eeden, M. Granato, P. Haffter, M. Hammerschmidt, et al. 1996. Neural degeneration mutants in the zebrafish, Danio rerio. Development. 123: 229-239. (Pubitemid 27056750)
-
(1996)
Development
, vol.123
, pp. 229-239
-
-
Furutani-Seiki, M.1
Jiang, Y.-J.2
Brand, M.3
Heisenberg, C.-P.4
Houart, C.5
Beuchle, D.6
Van Eeden, F.J.M.7
Granato, M.8
Haffter, P.9
Hammerschmidt, M.10
Kane, D.A.11
Kelsh, R.N.12
Mullins, M.C.13
Odenthal, J.14
Nusslein-Volhard, C.15
-
82
-
-
0028075206
-
Microtubule arrays of the zebrafish yolk cell: Organization and function during epiboly
-
Solnica-Krezel, L., and W. Driever. 1994. Microtubule arrays of the zebrafish yolk cell: organization and function during epiboly. Development. 120: 2443-2455. (Pubitemid 24268819)
-
(1994)
Development
, vol.120
, Issue.9
, pp. 2443-2455
-
-
Solnica-Krezel, L.1
Driever, W.2
-
83
-
-
33646205000
-
Multiple corticosteroid receptors in fish: From old ideas to new concepts
-
Prunet, P., A. Sturm, and S. Milla. 2006. Multiple corticosteroid receptors in fish: from old ideas to new concepts. Gen. Comp. Endocrinol. 147: 17-23.
-
(2006)
Gen. Comp. Endocrinol.
, vol.147
, pp. 17-23
-
-
Prunet, P.1
Sturm, A.2
Milla, S.3
-
84
-
-
41549093691
-
Discovery of a functional glucocorticoid receptor beta-isoform in zebrafish
-
Schaaf, M. J., D. Champagne, I. H. van Laanen, D. C. van Wijk, A. H. Meijer, O. C. Meijer, H. P. Spaink, and M. K. Richardson. 2008. Discovery of a functional glucocorticoid receptor beta-isoform in zebrafish. Endocrinology. 149: 1591-1599.
-
(2008)
Endocrinology
, vol.149
, pp. 1591-1599
-
-
Schaaf, M.J.1
Champagne, D.2
Van Laanen, I.H.3
Van Wijk, D.C.4
Meijer, A.H.5
Meijer, O.C.6
Spaink, H.P.7
Richardson, M.K.8
-
85
-
-
71549129819
-
Expression analysis of steroid hormone receptor mRNAs during zebrafish embryogenesis
-
Pikulkaew, S., A. De Nadai, P. Belvedere, L. Colombo, and L. Dalla Valle. 2010. Expression analysis of steroid hormone receptor mRNAs during zebrafish embryogenesis. Gen. Comp. Endocrinol. 165: 215-220.
-
(2010)
Gen. Comp. Endocrinol.
, vol.165
, pp. 215-220
-
-
Pikulkaew, S.1
De Nadai, A.2
Belvedere, P.3
Colombo, L.4
Dalla Valle, L.5
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