Glucocorticoids alter craniofacial development and increase expression and activity of matrix metalloproteinases in developing Zebrafish (Danio rerio)

Toxicological Sciences

Volumn 102, Issue 2, 2008, Pages 413-424

  Hillegass, Jedd M ^a,b   Villano, Caren M ^a,b   Cooper, Keith R ^a,b   White, Lori A ^a,b,c  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c The State University of New Jersey   (United States)

Author keywords

Development; Glucocorticoids; Matrix metalloproteinases; RU486; Zebrafish

Indexed keywords

COLLAGENASE 3; DEXAMETHASONE; GELATINASE A; GELATINASE B; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; MATRIX METALLOPROTEINASE; MESSENGER RNA; MIFEPRISTONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIODEGRADATION; CELL MIGRATION; CONTROLLED STUDY; CRANIOFACIAL MALFORMATION; DRUG MECHANISM; EMBRYO; EMBRYO DEVELOPMENT; FERTILIZATION; GENE EXPRESSION; IN SITU HYBRIDIZATION; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TERATOGENESIS;

ANIMALS; CRANIOFACIAL ABNORMALITIES; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; EMBRYO, NONMAMMALIAN; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLUCOCORTICOIDS; HORMONE ANTAGONISTS; HYDROCORTISONE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MIFEPRISTONE; RECEPTORS, GLUCOCORTICOID; ZEBRAFISH; ZEBRAFISH PROTEINS;

DANIO RERIO;

EID: 40949102164     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfn010     Document Type: Article

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