The Akt/GSK-3β pathway mediates flurbiprofen-induced neuroprotection against focal cerebral ischemia/reperfusion injury in rats

Biochemical and Biophysical Research Communications

Volumn 409, Issue 4, 2011, Pages 808-813

  Sun, Baozhu ^a,b   Chen, Lin ^a   Wei, Xinbing ^a   Xiang, Yanxiao ^a   Liu, Xiaoqian ^a   Zhang, Xiumei ^a  

^a SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Akt; Apoptosis; Flurbiprofen; GSK 3

Indexed keywords

FLURBIPROFEN AXETIL; GLYCOGEN SYNTHASE KINASE 3BETA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN PROTECTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL NECROSIS; NEUROLOGIC DISEASE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; BRAIN ISCHEMIA; CYTOPROTECTION; FLURBIPROFEN; GLYCOGEN SYNTHASE KINASE 3; MALE; NEUROPROTECTIVE AGENTS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; REPERFUSION INJURY;

RATTUS;

EID: 79959201790     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.05.095     Document Type: Article

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