Rutin from Lonicera japonica inhibits myocardial ischemia/reperfusion-induced apoptosis in vivo and protects H9c2 cells against hydrogen peroxide-mediated injury via ERK1/2 and PI3K/Akt signals in vitro

Food and Chemical Toxicology

Volumn 47, Issue 7, 2009, Pages 1569-1576

  Jeong, Jae Ju ^a   Ha, Yu Mi ^a   Jin, Yong Chun ^b   Lee, Eun Ju ^c   Kim, Ju Sun ^c   Kim, Hye Jung ^a   Seo, Han Geuk ^a   Lee, Jae Heun ^a   Kang, Sam Sik ^c   Kim, Yeung Shik ^c   Chang, Ki Churl ^a  

^a Gyeongsang National University School of Medicine   (South Korea)

^b YANBIAN UNIVERSITY   (China)

^c Seoul National University   (South Korea)

Author keywords

aPI3kinase; Apoptosis; ERK1 2 pathway; Ischemia reperfusion injury; Oxidative stress; Rutin

Indexed keywords

CASPASE 3; HYDROGEN PEROXIDE; LIPOCORTIN 5; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; RUTOSIDE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; HEART; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; IN VITRO STUDY; IN VIVO STUDY; ISOLATION PROCEDURE; LONICERA JAPONICA; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANNEXIN A5; APOPTOSIS; BLOTTING, WESTERN; CELL LINE; CELL SURVIVAL; HEMODYNAMICS; HYDROGEN PEROXIDE; IN SITU NICK-END LABELING; LONICERA; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MYOCARDIAL REPERFUSION INJURY; OXIDANTS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; RUTIN; SIGNAL TRANSDUCTION; TETRAZOLIUM SALTS; THIAZOLES;

LONICERA JAPONICA; RATTUS;

EID: 67349157005     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2009.03.044     Document Type: Article

References (34)

1. Abe Y., Matsumoto S., Kito K., and Ueda N. Cloning and expression of a novel MAPKK-like protein kinase, lymphokine-activated killer T-cell-originated protein kinase, specifically expressed in the testis and activated lymphoid cells. J. Biol. Chem. 275 (2000) 1525-1531
2. Amaravadi R., and Thompson C.B. The survival kinases Akt and Pim as potential pharmacological targets. J. Clin. Invest. 115 (2005) 2618-2624
3. Day A.J., DuPont M.S., Ridley S., Rhodes M., Rhodes M.J., Morgan M.R., and Williamson G. Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver beta-glucosidase activity. FEBS Lett. 436 (1998) 71-75
4. 2 -induced damage and iron homeostasis in human cells. Free Radical Bio. Med. 43 (2007) 1165-1175
5. Fang S.H., Rao Y.K., and Tzeng Y.M. Anti-oxidant and inflammatory mediator's growth inhibitory effects of compounds isolated from Phyllanthus urinaria. J. Ethnopharmacol. 116 (2008) 333-340
6. Gottlieb R.A., and Engler R.L. Apoptosis in myocardial ischemia-reperfusion. Ann. NY. Acad. Sci. 30 (1999) 412-426
7. Halestrap A.P., Clarke S.J., and Javadov S.A. Mitochondrial permeability transition pore opening during myocardial reperfusion - a target for cardioprotection. Cardiovasc. Res. 61 (2004) 372-385
8. Heo J.M., Kim H.J., Ha Y.M., Park M.K., Kang Y.J., Lee Y.S., Seo H.G., Lee J.H., Yun-Choi H.S., and Chang K.C. YS 51, 1-(beta-naphtylmethyl)-6,7-dihydroxy-1,2,3,4,tetrahydroisoquinoline, protects endothelial cells against hydrogen peroxide-induced injury via carbon monoxide derived from heme oxygenase-1. Biochem. Pharmacol. 74 (2007) 1361-1370
9. Ikizler M., Erkasap N., Dernek S., Kural T., and Kaygisiz Z. Dietary polyphenol quercetin protects rat hearts during reperfusion: enhanced antioxidant capacity with chronic treatment. Anadolu Kardiyol Derg. 7 (2007) 404-410
10. Jennings R.B., Murry C.E., and Reimer K.A. Energy metabolism in preconditioned and control myocardium: effect of total ischemia. J. Mol. Cell Cardiol. 23 (1991) 1449-1458
11. Jin Y.C., Kim K.J., Kim Y.M., Ha Y.M., Kim H.J., Yun U.J., Bae K.H., Kim Y.S., Kang S.S., Seo H.G., Lee J.H., and Chang K.C. Anti-apoptotic effect of magnolol in myocardial ischemia and reperfusion injury requires extracellular signal-regulated kinase1/2 pathways in rat in vivo. Exp. Biol. Med. (Maywood) 233 (2008) 1280-1288
12. Jin Y.C., Kim W., Ha Y.M., Shin I.W., Sohn J.T., Kim H.J., Seo H.G., Lee J.H., and Chang K.C. Propofol limits rat myocardial ischemia and reperfusion injury with an associated reduction in apoptotic cell death in vivo. Vascul. Pharmacol. 50 (2008) 71-77
13. Kirshenbaum L.A., and de Moissac D. The bcl-2 gene product prevents programmed cell death of ventricular myocytes. Circulation 96 (1997) 1580-1585
14. Kolchin Iu.N., Maksiutina N.P., Balanda P.P., Luǐk A.I., Bulakh V.N., and Moǐbenko A.A. The cardioprotective action of quercetin in experimental occlusion and reperfusion of the coronary artery in dogs. Farmakol. Toksikol. 54 (1991) 20-23
15. Kühnau J. The flavonoids. A class of semi-essential food components: their role in human nutrition. World Rev. Nutr. Diet. 24 (1976) 117-191
16. Lanteri R., Acquaviva R., Di Giacomo C., Sorrenti V., Li, Destri G., Santangelo M., Vanella L., and Di Cataldo A. Rutin in rat liver ischemia/reperfusion injury: effect on DDAH/NOS pathway. Microsurgery 27 (2007) 245-251
17. Lao C.J., Lin J.G., Kuo J.S., Chao P.D., Cheng C.Y., Tang N.Y., and Hsieh C.L. Microglia, apoptosis and interleukin-1beta expression in the effect of Sophora japonica on cerebral infarct induced by ischemia-reperfusion in rats. Am. J. Chinese Med. 33 (2005) 425-438
18. Lee Y.S., Kang Y.J., Kim H.J., Park M.K., Seo H.G., Lee J.H., Yun-Choi H.S., and Chang K.C. Higenamine reduces apoptotic cell death by induction of heme oxygenase-1 in rat myocardial ischemia-reperfusion injury. Apoptosis 11 (2006) 1091-1100
19. Lemasters J.J., and Thurman R.G. The many facets of reperfusion injury. Gastroenterology 108 (1995) 1317-1320
20. Misao J., Hayakawa Y., Ohno M., Kato S., Fujiwara T., and Fujiwara H. Expression of bcl-2 protein, an inhibitor of apoptosis, and Bax, an accelerator of apoptosis, in ventricular myocytes of human hearts with myocardial infarction. Circulation 94 (1996) 1506-1512
21. Mullonkal C.J., and Toledo-Pereyra L.H. Akt in ischemia and reperfusion. J. Invest. Surg. 20 (2007) 195-203
22. Nizamutdinova I.T., Jin Y.C., Kim J.S., Yean M.H., Kang S.S., Kim Y.S., Lee J.H., Seo H.G., Kim H.J., and Chang K.C. Paeonol and paeoniflorin, the main active principles of Paeonia albiflora, protect the heart from myocardial ischemia/reperfusion injury in rats. Planta Med. 74 (2008) 14-18
23. Ortolani O., Caggiano M., Mannelli R., Gogliettino A., and Tufano R. Protection from ischemia-reperfusion damage in patients with stroke: the role of rutin and GSH. Transplant. P. 27 (1995) 2877-2878
24. Pechtelidou A., Beis I., and Gaitanaki C. Transient and sustained oxidative stress differentially activate the JNK1/2 pathway and apoptotic phenotype in H9c2 cells. Mol. Cell. Biochem. 309 (2008) 177-189
25. Singla D.K., Singla R.D., and McDonald D.E. Factors released from embryonic stem cells inhibit apoptosis in H9c2 cells through PI3K/Akt but not ERK pathway. Am. J. Physiol - Heart C 29 (2008) H907-H913
26. Sun D.I., Nizamutdinova I.T., Kim Y.M., Cai X.F., Lee J.J., Kang S.S., Kim Y.S., Kang K.M., Chai G.Y., Chang K.C., and Kim H.J. Bisacurone inhibits adhesion of inflammatory monocytes or cancer cells to endothelial cells through down-regulation of VCAM-1 expression. Int. Immunopharmacol. 8 (2008) 1272-1281
27. Tsoyi K., Park H.B., Kim Y.M., Chung J.I., Shin S.C., Shim H.J., Lee W.S., Seo H.G., Lee J.H., Chang K.C., and Kim H.J. Protective Effect of Anthocyanins from Black Soybean Seed Coats on UVB-Induced Apoptotic Cell Death in Vitro and in Vivo. J. Agr. Food Chem. 56 (2008) 10600-10605
28. Turner N.A., Xia F., Azhar G., Zhang X., Liu L., and Wei J.Y. Oxidative stress induces DNA fragmentation and caspase activation via the c-Jun NH2-terminal kinase pathway in H9c2 cardiac muscle cells. J. Mol. Cell Cardiol. 30 (1998) 1789-1801
29. Volate S.R., Davenport D.M., Muga S.J., and Wargovich M.J. Modulation of aberrant crypt foci and apoptosis by dietary herbal supplements (quercetin, curcumin, silymarin, ginseng and rutin). Carcinogenesis 26 (2005) 1450-1456
30. Wu H.C., Yeh Y.L., Kuo W.W., Huang S.K., Kuo W.H., Hsieh D.J., Wu C.L., Tsai C.H., Lee S.D., and Huang C.Y. P38 mitogen-activated protein kinase pathways are involved in the hypertrophy and apoptosis of cardiomyocytes induced by Porphyromonas gingivalis conditioned medium. Cell Biochem. Funct. 26 (2008) 246-255
31. Yamashita N., Hoshida S., Otsu K., Taniguchi N., Kuzuya T., and Hori M. Monophosphoryl lipid A provides biphasic cardioprotection against ischaemia-reperfusion injury in rat hearts. Brit. J. Pharmacol. 128 (1999) 412-418
32. Yue G.K. Retrieval of stratospheric aerosol size distributions and integral properties from simulated lidar backscatter measurements. Appl. Optics 39 (2000) 5446-5455
33. Zhao X., Geltinger C., Kishikawa S., Ohshima K., Murata T., Nomura N., Nakahara T., and Yokoyama K.K. Treatment of mouse melanoma cells with phorbol 12-myristate 13-acetate counteracts mannosylerythritol lipid-induced growth arrest and apoptosis. Cytotechnology 33 (2000) 123-130
34. Zhu X., Liu B., Zhou S., Chen Y.R., Deng Y., Zweier J.L., and He G. Ischemic preconditioning prevents in vivo hyperoxygenation in postischemic myocardium with preservation of mitochondrial oxygen consumption. Am. J. Physiol - Heart C 293 (2007) 1442-1450