메뉴 건너뛰기




Volumn 9, Issue 6, 2011, Pages 766-781

NFBD1/MDC1 regulates Cav1 and Cav2 independently of DNA damage and p53

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CAVEOLIN 1; CAVEOLIN 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN P53; SHORT HAIRPIN RNA;

EID: 79959193627     PISSN: 15417786     EISSN: 15573125     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-10-0317     Document Type: Article
Times cited : (10)

References (58)
  • 1
    • 0031046294 scopus 로고    scopus 로고
    • A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins
    • Bork P, Hofmann K, Bucher P, Neuwald AF, Altschul SF, Koonin EV. A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins. Faseb J 1997;11:68-76.
    • (1997) Faseb J , vol.11 , pp. 68-76
    • Bork, P.1    Hofmann, K.2    Bucher, P.3    Neuwald, A.F.4    Altschul, S.F.5    Koonin, E.V.6
  • 2
    • 0037424296 scopus 로고    scopus 로고
    • NFBD1/KIAA0170 is a chromatin-associated protein involved in DNA damage signaling pathways
    • DOI 10.1074/jbc.M211392200
    • Xu X, Stern DF. NFBD1/KIAA0170 is a chromatin-associated protein involved in DNA damage signaling pathways. J Biol Chem 2003;278:8795-803. (Pubitemid 36800637)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.10 , pp. 8795-8803
    • Xu, X.1    Sterns, D.F.2
  • 3
    • 0037468192 scopus 로고    scopus 로고
    • MDC1 is a mediator of the mammalian DNA damage checkpoint
    • DOI 10.1038/nature01446
    • Stewart GS, Wang B, Bignell CR, Taylor AM, Elledge SJ. MDC1 is a mediator of the mammalian DNA damage checkpoint. Nature 2003;421:961-6. (Pubitemid 36288029)
    • (2003) Nature , vol.421 , Issue.6926 , pp. 961-966
    • Stewart, G.S.1    Wang, B.2    Bigneli, C.R.3    Taylor, A.M.R.4    Elledge, S.J.5
  • 4
    • 0037458608 scopus 로고    scopus 로고
    • NFBD1, a novel nuclear protein with signature motifs of FHA and BRCT, and an internal 41-amino acid repeat sequence, is an early participant in DNA damage response
    • DOI 10.1074/jbc.M210749200
    • Shang YL, Bodero AJ, Chen PL. NFBD1, a novel nuclear protein with signature motifs of FHA and BRCT, and an internal 41-amino acid repeat sequence, is an early participant in DNA damage response. J Biol Chem 2003;278:6323-9. (Pubitemid 36800890)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.8 , pp. 6323-6329
    • Shang, Y.L.1    Bodero, A.J.2    Chen, P.-L.3
  • 6
    • 0037468232 scopus 로고    scopus 로고
    • MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways
    • DOI 10.1038/nature01447
    • Lou Z, Minter-Dykhouse K, Wu X, Chen J. MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways. Nature 2003;421:957-61. (Pubitemid 36288028)
    • (2003) Nature , vol.421 , Issue.6926 , pp. 957-961
    • Lou, Z.1    Minter-Dykhouse, K.2    Wu, X.3    Chen, J.4
  • 10
    • 42449086413 scopus 로고    scopus 로고
    • Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin
    • DOI 10.1083/jcb.200708210
    • Melander F, Bekker-Jensen S, Falck J, Bartek J, Mailand N, Lukas J. Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin. J Cell Biol 2008;181:213-26. (Pubitemid 351574548)
    • (2008) Journal of Cell Biology , vol.181 , Issue.2 , pp. 213-226
    • Melander, F.1    Bekker-Jensen, S.2    Falck, J.3    Bartek, J.4    Mailand, N.5    Lukas, J.6
  • 11
    • 48649100438 scopus 로고    scopus 로고
    • Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage
    • Chapman JR, Jackson SP. Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage. EMBO Rep 2008;9:795-801.
    • (2008) EMBO Rep , vol.9 , pp. 795-801
    • Chapman, J.R.1    Jackson, S.P.2
  • 12
    • 49649089537 scopus 로고    scopus 로고
    • MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks
    • Wu L, Luo K, Lou Z, Chen J. MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks. Proc Natl Acad Sci U S A 2008;105:11200-5.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 11200-11205
    • Wu, L.1    Luo, K.2    Lou, Z.3    Chen, J.4
  • 13
    • 0141780833 scopus 로고    scopus 로고
    • NFBD1/MDC1 regulates ionizing radiation-induced focus formation by DNA checkpoint signaling and repair factors
    • DOI 10.1096/fj.03-0310com
    • Xu X, Stern DF. NFBD1/MDC1 regulates ionizing radiation-induced focus formation by DNA checkpoint signaling and repair factors. Faseb J 2003;17:1842-8. (Pubitemid 37214778)
    • (2003) FASEB Journal , vol.17 , Issue.13 , pp. 1842-1848
    • Xu, X.1    Stern, D.F.2
  • 15
    • 2442444916 scopus 로고    scopus 로고
    • Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation
    • DOI 10.1038/sj.onc.1207447
    • Horejsi Z, Falck J, Bakkenist CJ, Kastan MB, Lukas J, Bartek J. Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation. Oncogene 2004;23:3122-7. (Pubitemid 38648203)
    • (2004) Oncogene , vol.23 , Issue.17 , pp. 3122-3127
    • Horejsi, Z.1    Falck, J.2    Bakkenist, C.J.3    Kastan, M.B.4    Lukas, J.5    Bartek, J.6
  • 16
    • 0142136826 scopus 로고    scopus 로고
    • Requirement of the MRN complex for ATM activation by DNA damage
    • DOI 10.1093/emboj/cdg541
    • Uziel T, Lerenthal Y, Moyal L, Andegeko Y, Mittelman L, Shiloh Y. Requirement of the MRN complex for ATM activation by DNA damage. Embo J 2003;22:5612-21. (Pubitemid 37279970)
    • (2003) EMBO Journal , vol.22 , Issue.20 , pp. 5612-5621
    • Uziel, T.1    Lerenthal, Y.2    Moyal, L.3    Andegeko, Y.4    Mittelman, L.5    Shiloh, Y.6
  • 18
    • 4544355447 scopus 로고    scopus 로고
    • Independent roles for nibrin and Mre11-Rad50 in the activation and function of Atm
    • DOI 10.1074/jbc.M404294200
    • Cerosaletti K, Concannon P. Independent Roles for Nibrin and Mre11-Rad50 in the Activation and Function of Atm. J Biol Chem 2004;279: 38813-9. (Pubitemid 39296040)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.37 , pp. 38813-38819
    • Cerosaletti, K.1    Concannon, P.2
  • 19
    • 17644409069 scopus 로고    scopus 로고
    • ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
    • DOI 10.1126/science.1108297
    • Lee JH, Paull TT. ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex. Science 2005;308:551-4. (Pubitemid 40570585)
    • (2005) Science , vol.308 , Issue.5721 , pp. 551-554
    • Lee, J.-H.1    Paull, T.T.2
  • 20
    • 1842431822 scopus 로고    scopus 로고
    • Direct Activation of the ATM Protein Kinase by the Mre11/Rad50/Nbs1 Complex
    • DOI 10.1126/science.1091496
    • Lee JH, Paull TT. Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex. Science 2004;304:93-6. (Pubitemid 38451463)
    • (2004) Science , vol.304 , Issue.5667 , pp. 93-96
    • Lee, J.-H.1    Paull, T.T.2
  • 21
    • 20744436198 scopus 로고    scopus 로고
    • ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1
    • DOI 10.1128/MCB.25.13.5363-5379.2005
    • You Z, Chahwan C, Bailis J, Hunter T, Russell P. ATM Activation and Its Recruitment to Damaged DNA Require Binding to the C Terminus of Nbs1. Mol Cell Biol 2005;25:5363-79. (Pubitemid 40853574)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.13 , pp. 5363-5379
    • You, Z.1    Chahwan, C.2    Bailis, J.3    Hunter, T.4    Russell, P.5
  • 22
    • 58849135489 scopus 로고    scopus 로고
    • Differential DNA damage signaling accounts for distinct neural apoptotic responses in ATLD and NBS
    • Shull ER, Lee Y, Nakane H, Stracker TH, Zhao J, Russell HR, et al. Differential DNA damage signaling accounts for distinct neural apoptotic responses in ATLD and NBS. Genes Dev 2009;23:171-80.
    • (2009) Genes Dev , vol.23 , pp. 171-180
    • Shull, E.R.1    Lee, Y.2    Nakane, H.3    Stracker, T.H.4    Zhao, J.5    Russell, H.R.6
  • 23
    • 52949109260 scopus 로고    scopus 로고
    • Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation
    • Buis J, Wu Y, Deng Y, Leddon J, Westfield G, Eckersdorff M, et al. Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation. Cell 2008;135:85-96.
    • (2008) Cell , vol.135 , pp. 85-96
    • Buis, J.1    Wu, Y.2    Deng, Y.3    Leddon, J.4    Westfield, G.5    Eckersdorff, M.6
  • 26
    • 77958009227 scopus 로고    scopus 로고
    • Quantitative proteomics of caveolin-1-regulated proteins: Characterization of polymerase i and transcript release factor/CAVIN-1 in endothelial cells
    • Dávalos A, Fernández-Hernando C, Sowa G, Derakhshan B, Lin MI, Lee JY, et al. Quantitative proteomics of caveolin-1-regulated proteins: characterization of polymerase i and transcript release factor/CAVIN-1 IN endothelial cells. Mol Cell Proteomics; 9:2109-24.
    • Mol Cell Proteomics , vol.9 , pp. 2109-2124
    • Dávalos, A.1    Fernández-Hernando, C.2    Sowa, G.3    Derakhshan, B.4    Lin, M.I.5    Lee, J.Y.6
  • 27
    • 56449084007 scopus 로고    scopus 로고
    • NFBD1/MDC1, 53BP1 and BRCA1 have both redundant and unique roles in the ATM pathway
    • Wilson KA, Stern DF. NFBD1/MDC1, 53BP1 and BRCA1 have both redundant and unique roles in the ATM pathway. Cell Cycle 2008;7:3584-94.
    • (2008) Cell Cycle , vol.7 , pp. 3584-3594
    • Wilson, K.A.1    Stern, D.F.2
  • 28
    • 52449102121 scopus 로고    scopus 로고
    • Repression of the SUMO-specific protease Senp1 induces p53-dependent premature senescence in normal human fibroblasts
    • Yates KE, Korbel GA, Shtutman M, Roninson IB, DiMaio D. Repression of the SUMO-specific protease Senp1 induces p53-dependent premature senescence in normal human fibroblasts. Aging Cell 2008;7:609-21.
    • (2008) Aging Cell , vol.7 , pp. 609-621
    • Yates, K.E.1    Korbel, G.A.2    Shtutman, M.3    Roninson, I.B.4    DiMaio, D.5
  • 29
    • 56949098754 scopus 로고    scopus 로고
    • Caveolin-1 negatively regulates TRAIL-induced apoptosis in human hepatocarcinoma cells
    • Zhao X, Liu Y, Ma Q, Wang X, Jin H, Mehrpour M, et al. Caveolin-1 negatively regulates TRAIL-induced apoptosis in human hepatocarcinoma cells. Biochem Biophys Res Commun 2009;378:21-6.
    • (2009) Biochem Biophys Res Commun , vol.378 , pp. 21-26
    • Zhao, X.1    Liu, Y.2    Ma, Q.3    Wang, X.4    Jin, H.5    Mehrpour, M.6
  • 30
    • 0029955714 scopus 로고    scopus 로고
    • The pCL vector system: Rapid production of helper-free, high-titer, recombinant retroviruses
    • Naviaux RK, Costanzi E, Haas M, Verma IM. The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses. J Virol 1996;70:5701-5. (Pubitemid 26240755)
    • (1996) Journal of Virology , vol.70 , Issue.8 , pp. 5701-5705
    • Naviaux, R.K.1    Costanzi, E.2    Haas, M.3    Verma, I.M.4
  • 32
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical bayes methods for assessing differential expression in microarray experiments
    • Article3
    • Smyth GK. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 2004;3:Article3.
    • (2004) Stat Appl Genet Mol Biol , vol.3
    • Smyth, G.K.1
  • 33
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Statist Soc B 1995;57:289-300.
    • (1995) J R Statist Soc B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 34
    • 2142647335 scopus 로고    scopus 로고
    • The biology of caveolae: Lessons from caveolin knockout mice and implications for human disease
    • Hnasko R, Lisanti MP. The biology of caveolae: lessons from caveolin knockout mice and implications for human disease. Mol Interv 2003;3:445-64.
    • (2003) Mol Interv , vol.3 , pp. 445-464
    • Hnasko, R.1    Lisanti, M.P.2
  • 35
    • 0032538790 scopus 로고    scopus 로고
    • Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade
    • Galbiati F, Volonte D, Engelman JA, Watanabe G, Burk R, Pestell RG, et al. Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade. Embo J 1998;17:6633-48. (Pubitemid 28521797)
    • (1998) EMBO Journal , vol.17 , Issue.22 , pp. 6633-6648
    • Galbiati, F.1    Volonte, D.2    Engelman, J.A.3    Watanabe, G.4    Burk, R.5    Pestell, R.G.6    Lisanti, M.P.7
  • 36
  • 37
    • 34948904709 scopus 로고    scopus 로고
    • Reexpression of caveolin-1 in endothelium rescues the vascular, cardiac, and pulmonary defects in global caveolin-1 knockout mice
    • DOI 10.1084/jem.20062340
    • Murata T, Lin MI, Huang Y, Yu J, Bauer PM, Giordano FJ, et al. Reexpression of caveolin-1 in endothelium rescues the vascular, cardiac, and pulmonary defects in global caveolin-1 knockout mice. J Exp Med 2007;204:2373-82. (Pubitemid 47529323)
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.10 , pp. 2373-2382
    • Murata, T.1    Lin, M.I.2    Huang, Y.3    Yu, J.4    Bauer, P.M.5    Giordano, F.J.6    Sessa, W.C.7
  • 39
    • 0029803093 scopus 로고    scopus 로고
    • Src Tyrosine Kinases, Galpha Subunits, and H-Ras Share a Common Membrane-anchored Scaffolding Protein, Caveolin
    • Li S, Couet J, Lisanti MP. Src Tyrosine Kinases, Galpha Subunits, and H-Ras Share a Common Membrane-anchored Scaffolding Protein, Caveolin. J Biol Chem 1996;271:29182-90.
    • (1996) J Biol Chem , vol.271 , pp. 29182-29190
    • Li, S.1    Couet, J.2    Lisanti, M.P.3
  • 40
    • 0029075372 scopus 로고
    • Evidence for a Regulated Interaction between Heterotrimeric G Proteins and Caveolin
    • Li S, Okamoto T, Chun M, Sargiacomo M, Casanova JE, Hansen SH, et al. Evidence for a Regulated Interaction between Heterotrimeric G Proteins and Caveolin. J Biol Chem 1995;270:15693-701.
    • (1995) J Biol Chem , vol.270 , pp. 15693-15701
    • Li, S.1    Okamoto, T.2    Chun, M.3    Sargiacomo, M.4    Casanova, J.E.5    Hansen, S.H.6
  • 43
    • 0032577647 scopus 로고    scopus 로고
    • Caveolin-mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo. A role for the caveolin-scaffolding domain
    • Engelman JA, Chu C, Lin A, et al. Caveolin-mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo. A role for the caveolin-scaffolding domain. FEBS Lett 1998;428:205-11.
    • (1998) FEBS Lett , vol.428 , pp. 205-211
    • Engelman, J.A.1    Chu, C.2    Lin, A.3
  • 45
    • 52049095769 scopus 로고    scopus 로고
    • Growth suppression of MCF-7 cancer cell-derived xenografts in nude mice by caveolin-1
    • Wu P, Wang X, Li F, Qi B, Zhu H, Liu S, et al. Growth suppression of MCF-7 cancer cell-derived xenografts in nude mice by caveolin-1. Biochem Biophys Res Commun 2008;376:215-20.
    • (2008) Biochem Biophys Res Commun , vol.376 , pp. 215-220
    • Wu, P.1    Wang, X.2    Li, F.3    Qi, B.4    Zhu, H.5    Liu, S.6
  • 47
    • 33749000596 scopus 로고    scopus 로고
    • The role of BRCA1 in transcriptional regulation and cell cycle control
    • DOI 10.1038/sj.onc.1209872, PII 1209872
    • Mullan PB, Quinn JE, Harkin DP. The role of BRCA1 in transcriptional regulation and cell cycle control. Oncogene 2006;25:5854-63. (Pubitemid 44453441)
    • (2006) Oncogene , vol.25 , Issue.43 , pp. 5854-5863
    • Mullan, P.B.1    Quinn, J.E.2    Harkin, D.P.3
  • 48
    • 35848935069 scopus 로고    scopus 로고
    • DNA damage response mediators MDC1 and 53BP1: Constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours
    • DOI 10.1038/sj.onc.1210553, PII 1210553
    • Bartkova J, Horejsí Z, Sehested M, Nesland JM, Rajpert-De Meyts E, Skakkebaek NE, et al. DNA damage response mediators MDC1 and 53BP1: constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours. Oncogene 2007;26:7414-22. (Pubitemid 350158716)
    • (2007) Oncogene , vol.26 , Issue.53 , pp. 7414-7422
    • Bartkova, J.1    Horejsi, Z.2    Sehested, M.3    Nesland, J.M.4    Rajpert-De, M.E.5    Skakkebaek, N.E.6    Stucki, M.7    Jackson, S.8    Lukas, J.9    Bartek, J.10
  • 50
    • 0037905722 scopus 로고    scopus 로고
    • Caveolin-1 and caveolin-2, together with three bone morphogenetic protein-related genes, may encode novel tumor suppressors down-regulated in sporadic follicular thyroid carcinogenesis
    • Aldred MA, Ginn-Pease ME, Morrison CD, Popkie AP, Gimm O, Hoang-Vu C, et al. Caveolin-1 and caveolin-2,together with three bone morphogenetic protein-related genes, may encode novel tumor suppressors down-regulated in sporadic follicular thyroid carcinogenesis. Cancer Res 2003;63:2864-71. (Pubitemid 36667158)
    • (2003) Cancer Research , vol.63 , Issue.11 , pp. 2864-2871
    • Aldred, M.A.1    Ginn-Pease, M.E.2    Morrison, C.D.3    Popkie, A.P.4    Gimm, O.5    Hoang-Vu, C.6    Krause, U.7    Dralle, H.8    Jhiang, S.M.9    Plass, C.10    Eng, C.11
  • 52
    • 0028953271 scopus 로고
    • Reduction of caveolin and caveolae in oncogenically transformed cells
    • Koleske AJ, Baltimore D, Lisanti MP. Reduction of caveolin and caveolae in oncogenically transformed cells. Proc Natl Acad Sci U S A 1995;92:1381-5.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 1381-1385
    • Koleske, A.J.1    Baltimore, D.2    Lisanti, M.P.3
  • 53
    • 67649794703 scopus 로고    scopus 로고
    • Oxidative stress is linked to ERK1/2-p16 signaling-mediated growth defect in ATM-deficient astrocytes
    • Kim J, Wong PK. Oxidative stress is linked to ERK1/2-p16 signaling-mediated growth defect in ATM-deficient astrocytes. J Biol Chem 2009;284:14396-404.
    • (2009) J Biol Chem , vol.284 , pp. 14396-14404
    • Kim, J.1    Wong, P.K.2
  • 54
    • 27944476980 scopus 로고    scopus 로고
    • ATM deficiency induces oxidative stress and endoplasmic reticulum stress in astrocytes
    • DOI 10.1038/labinvest.3700354, PII 3700354
    • Liu N, Stoica G, Yan M, Scofield VL, Qiang W, Lynn WS, et al. ATM deficiency induces oxidative stress and endoplasmic reticulum stress in astrocytes. Lab Invest 2005;85:1471-80. (Pubitemid 41662332)
    • (2005) Laboratory Investigation , vol.85 , Issue.12 , pp. 1471-1480
    • Liu, N.1    Stoica, G.2    Yan, M.3    Scofield, V.L.4    Qiang, W.5    Lynn, W.S.6    Wong, P.K.Y.7
  • 55
    • 2942726209 scopus 로고    scopus 로고
    • BRCA1 inhibits membrane estrogen and growth factor receptor signaling to cell proliferation in breast cancer
    • DOI 10.1128/MCB.24.13.5900-5913.2004
    • Razandi M, Pedram A, Rosen EM, Levin ER. BRCA1 inhibits membrane estrogen and growth factor receptor signaling to cell proliferation in breast cancer. Mol Cell Biol 2004;24:5900-13. (Pubitemid 38787974)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.13 , pp. 5900-5913
    • Razandi, M.1    Pedram, A.2    Rosen, E.M.3    Levin, E.R.4
  • 56
    • 42449153673 scopus 로고    scopus 로고
    • BRCA1 regulates caveolin-1 expression and inhibits cell invasiveness
    • Wang Y, Yu J, Zhan Q. BRCA1 regulates caveolin-1 expression and inhibits cell invasiveness. Biochem Biophys Res Commun 2008;370:201-6.
    • (2008) Biochem Biophys Res Commun , vol.370 , pp. 201-206
    • Wang, Y.1    Yu, J.2    Zhan, Q.3
  • 57
    • 0032504784 scopus 로고    scopus 로고
    • p19(ARF) links the tumour suppressor p53 to Ras [6]
    • DOI 10.1038/25870
    • Palmero I, Pantoja C, Serrano M. p19ARF links the tumour suppressor p53 to Ras. Nature 1998;395:125-6. (Pubitemid 28425643)
    • (1998) Nature , vol.395 , Issue.6698 , pp. 125-126
    • Palmero, I.1    Pantoja, C.2    Serrano, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.