The influence of MHC and immunoglobulins A and e on host resistance to gastrointestinal nematodes in sheep

Journal of Parasitology Research

Volumn 2011, Issue , 2011, Pages

  Lee, C Y ^a   Munyard, K A ^a   Gregg, K ^a   Wetherall, J D ^a   Stear, M J ^b   Groth, D M ^a  

^a CURTIN UNIVERSITY   (Australia)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHELMINTIC AGENT; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; MAJOR HISTOCOMPATIBILITY ANTIGEN;

ADAPTIVE IMMUNITY; ANTIBODY PRODUCTION; DRUG EFFECT; EOSINOPHILIA; GASTROINTESTINAL INFECTION; HEREDITY; HOST RESISTANCE; HUMORAL IMMUNITY; INFECTION RESISTANCE; INFECTION SENSITIVITY; INFESTATION; NEMATODE; NEMATODIASIS; NONHUMAN; PARASITE IMMUNITY; PRIORITY JOURNAL; REVIEW; SHEEP;

ANIMALIA; NEMATODA; OVIS ARIES;

EID: 79959187465     PISSN: 20900023     EISSN: 20900031     Source Type: Journal    
DOI: 10.1155/2011/101848     Document Type: Review

References (126)

1. Karlsson L. J. E., Greeff J. C., Selection response in fecal worm egg counts in the Rylington Merino parasite resistant flock Australian Journal of Experimental Agriculture 2006 46 6-7 809 811 (Pubitemid 43944666)
2. Kemper K. E., Palmer D. G., Liu S. M., Greeff J. C., Bishop S. C., Karlsson L. J. E., Reduction of faecal worm egg count, worm numbers and worm fecundity in sheep selected for worm resistance following artificial infection with Teladorsagia circumcincta and Trichostrongylus colubriformis Veterinary Parasitology 2010 171 238 246
3. Morris C. A., Watson T. G., Bisset S. A., Vlassoff A., Douch P. G. C., Gray G. D., Woolaston R. R., Eaton B. D., Breeding sheep in New Zealand for resistance or resilience to nematode parasites Breeding for Resistance to Infectious Diseases of Small Ruminants 2000 Canberra, Australia ACIAR Monograph 77 98
4. Woolaston R. R., Windon R. G., Selection of sheep for response to Trichostrongylus colubriformis colubriformis larvae: genetic parameters Animal Science 2001 73 1 41 48
5. McEwan J. C., Dodds K. G., Greer G. J., Genetic estimates for parasite resistance traits in sheep and their correlations with production traits New Zealand Journal of Zoology 1995 22 177
6. Bisset S. A., Vlassoff A., Morris C. A., Southey B. R., Baker R. L., Parker A. G. H., Heritability of and genetic correlations among faecal egg counts and productivity traits in Romney sheep New Zealand Journal of Agricultural Research 1992 35 51 58
7. Eady S. J., Woolaston R. R., Lewer R. P., Raadsma H. W., Swan A. A., Ponzoni R. W., Resistance to nematode parasites in Merino sheep: correlation with production traits Australian Journal of Agricultural Research 1998 49 8 1201 1211 (Pubitemid 28494515)
8. Bishop S. C., Bairden K., McKellar Q. A., Park M., Stear M. J., Genetic parameters for faecal egg count following mixed, natural, predominantly Ostertagia circumcincta infection and relationships with live weight in young lambs Animal Science 1996 63 3 423 428
9. Stear M. J., Bairden K., Duncan J. L., Holmes P. H., McKellar Q. A., Park M., Strain S., Murray M., How hosts control worms Nature 1997 389 6646 27
10. Bouix J., Krupinski J., Rzepecki R., Nowosad B., Skrzyzala I., Roborzynski M., Fudalewicz-Niemczyk W., Skalska M., Malczewski A., Gruner L., Genetic resistance to gastrointestinal nematode parasites in polish long-wool sheep International Journal for Parasitology 1998 28 11 1797 1804 (Pubitemid 28522217)
11. Stear M. J., Bishop S. C., Henderson N. G., Scott I., A key mechanism of pathogenesis in sheep infected with the nematode Teladorsagia circumcincta Animal Health Research Reviews 2003 4 1 45 52
12. Behnke J. M., Iraqi F., Menge D., Baker R. L., Gibson J., Wakelin D., Chasing the genes that control resistance to gastrointestinal nematodes Journal of Helminthology 2003 77 2 99 109 (Pubitemid 36622374)
13. Khan W. I., Physiological changes in the gastrointestinal tract and host protective immunity: learning from the mouse- Trichinella spiralis model Parasitology 2008 135 6 671 682 (Pubitemid 351733166)
14. Mulcahy G., O'Neill S., Donnelly S., Dalton J. P., Helminths at mucosal barriersinteraction with the immune system Advanced Drug Delivery Reviews 2004 56 6 853 868 (Pubitemid 38520103)
15. Acheson D. W. K., Luccioli S., Microbial-gut interactions in health and disease. Mucosal immune responses Best Practice and Research Clinical Gastroenterology 2004 18 387 404
16. Maizels R. M., Yazdanbakhsh M., Immune regulation by helminth parasites: cellular and molecular mechanisms Nature Reviews Immunology 2003 3 9 733 744 (Pubitemid 41070814)
17. Janeway C. A., Travers P., Walport M., Schlomchik M., Immunobiology: The Immune System in Health and Disease 2001 Edinburgh, UK Churchill Levingstone
18. Diez-Tascn C., Keane O. M., Wilson T., Zadissa A., Hyndman D. L., Baird D. B., McEwan J. C., Crawford A. M., Microarray analysis of selection lines from outbred populations to identify genes involved with nematode parasite resistance in sheep Physiological Genomics 2005 21 59 69 (Pubitemid 40898465)
19. MacKinnon K. M., Burton J. L., Zajac A. M., Notter D. R., Microarray analysis reveals difference in gene expression profiles of hair and wool sheep infected with Haemonchus contortus Veterinary Immunology and Immunopathology 2009 130 3-4 210 220
20. Keane O. M., Dodds K. G., Crawford A. M., McEwan J. C., Transcriptional profiling of Ovis aries identifies Ovar-DQA1 allele frequency differences between nematode-resistant and susceptible selection lines Physiological Genomics 2007 30 3 253 261 (Pubitemid 47296185)
21. Forrest R. H.J., Zhou H., Fang Q., Smyth A., Frampton C. M., Hickford J. G.H., No evidence for a universal association between variation in faecal egg count for a mixed field-challenge of gastrointestinal parasites and the presence of the Ovar-DQA1 null haplotype in sheep Veterinary Immunology and Immunopathology 2010 135 3-4 303 305
22. Paterson S., Wilson K., Pemberton J. M., Major histocompatibility complex variation associated with juvenile survival and parasite resistance in a large unmanaged ungulate population (Ovis aries L.) Proceedings of the National Academy of Sciences of the United States of America 1998 95 7 3714 3719 (Pubitemid 28173194)
23. Outteridge P. M., Andersson L., Douch P. G. C., Green R. S., Gwakisa P. S., Hohenhaus M. A., Mikko S., The PCR typing of MHC-DRB genes in the sheep using primers for an intronic microsatellite: application to nematode parasite resistance Immunology and Cell Biology 1996 74 4 330 336 (Pubitemid 26281466)
24. Schwaiger F. W., Gostomski D., Stear M. J., Duncan J. L., McKellar Q. A., Epplen J. T., Buitkamp J., An ovine major histocompatibility complex DRB1 allele is associated with low faecal egg counts following natural, predominantly Ostertagia circumcincta infection International Journal for Parasitology 1995 25 7 815 822
25. Sayers G., Good B., Hanrahan J. P., Ryan M., Angles J. M., Sweeney T., Major Histocompatibility Complex DRB1 gene: its role in nematode resistance in Suffolk and Texel sheep breeds Parasitology 2005 131 3 403 409 (Pubitemid 41277740)
26. Buitkamp J., Filmether P., Stear M. J., Epplen J. T., Class I and class II major histocompatibility complex alleles are associated with faecal egg counts following natural, predominantly Ostertagia ciucumcincta infection Parasitology Research 1996 82 8 693 696
27. Stear M. J., Belch A., Donskow-Schmelter K., Fitton L. A., Innocent G. T., Ishikane C., Mateus A., Murphy L., Rennie K., Smith A., Sayers G., Detection of genes with moderate effects on disease resistance using ovine mhc and resistance to nematodes as an example Veterinary Immunology and Immunopathology 2007 120 1-2 3 9 (Pubitemid 47464609)
28. Figueroa Castillo J. A., Medina R. D.M., Villalobos J. M.B., Gayosso-Vzquez A., Ulloa-Arvzu R., Rodrguez R. A., Ramrez H. P., Alonso Morales R. A., Association between major histocompatibility complex microsatellites, fecal egg count, blood packed cell volume and blood eosinophilia in Pelibuey sheep infected with Haemonchus contortus. Veterinary Parasitology. In press
29. Davies G., Stear M. J., Benothman M., Abuagob O., Kerr A., Mitchell S., Bishop S. C., Quantitative trait loci associated with parasitic infection in Scottish Blackface sheep Heredity 2006 96 3 252 258
30. Gutierrez-Espeleta G. A., Hedrick P. W., Kalinowski S. T., Garrigan D., Boyce W. M., Is the decline of desert bighorn sheep from infectious disease the result of low MHC variation? Heredity 2001 86 4 439 450 (Pubitemid 32745305)
31. Rodrigues R. M., Silva N. M., Gonalves A. L.R., Cardoso C. R., Alves R., Gonalves F. A., Beletti M. E., Ueta M. T., Silva J. S., Costa-Cruz J. M., Major histocompatibility complex (MHC) class II but not MHC class i molecules are required for efficient control of Strongyloides venezuelensis infection in mice Immunology 2009 128 1 e432 e441
32. Iraqi F. A., Behnke J. M., Menge D. M., Lowe A., Teale A. J., Gibson J. P., Baker L. R., Wakelin D., Chromosomal regions controlling resistance to gastro-intestinal nematode infections in mice Mammalian Genome 2003 14 3 184 191 (Pubitemid 36269803)
33. Behnke J. M., Iraqi F. A., Mugambi J. M., Clifford S., Nagda S., Wakelin D., Kemp S. J., Baker R. L., Gibson J. P., High resolution mapping of chromosomal regions controlling resistance to gastrointestinal nematode infections in an advanced intercross line of mice Mammalian Genome 2006 17 6 584 597
34. Froeschke G., Sommer S., MHC class II DRB variability and parasite load in the striped mouse (Rhabdomys pumilio) in the Southern Kalahari Molecular Biology and Evolution 2005 22 5 1254 1259 (Pubitemid 40577763)
35. Meyer-Lucht Y., Sommer S., MHC diversity and the association to nematode parasitism in the yellow-necked mouse (Apodemus flavicollis) Molecular Ecology 2005 14 7 2233 2243 (Pubitemid 40772435)
36. Schad J., Ganzhorn J. U., Sommer S., Parasite burden and constitution of major histocompatibility complex in the Malagasy mouse lemur, Microcebus murinus Evolution 2005 59 2 439 450 (Pubitemid 40356055)
37. Grencis R. K., Riedlinger J., Wakelin D., L3T4-positive T lymphoblasts are responsible for transfer of immunity to Trichinella spiralis in mice Immunology 1985 56 2 213 218 (Pubitemid 15231394)
38. Rotman H. L., Schnyder-Candrian S., Scott P., Nolan T. J., Schad G. A., Abraham D., IL-12 eliminates the Th-2 dependent protective immune response of mice to larval Strongyloides stercoralis Parasite Immunology 1997 19 1 29 39 (Pubitemid 27046945)
39. Gill H. S., Watson D. L., Brandon M. R., Monoclonal antibody to CD4 + T cells abrogates genetic resistance to Haemonchus contortus in sheep Immunology 1993 78 1 43 49 (Pubitemid 23035847)
40. Stear M. J., Strain S., Bishop S. C., How lambs control infection with Ostertagia circumcincta Veterinary Immunology and Immunopathology 1999 72 1-2 213 218
41. Stear M. J., Strain S., Bishop S. C., Mechanisms underlying resistance to nematode infection International Journal for Parasitology 1999 29 1 51 56 (Pubitemid 29042247)
42. Stear M. J., Bishop S. C., The curvilinear relationship between worm length and fecundity of Teladorsagia circumcincta International Journal for Parasitology 1999 29 5 777 780 (Pubitemid 29319750)
43. Wakelin D., Axford R. E. F., Bishop S. C., Nicholas F. W., Owen J. B., Rodent models of genetic resistance to parasite infections Breeding for Disease Resistance in Farm Animals 2000 2nd Wallingford, Wash, USA CAB International 107 126
44. Kanobana K., Ploeger H. W., Vervelde L., Immune expulsion of the trichostrongylid Cooperia oncophora is associated with increased eosinophilia and mucosal IgA International Journal for Parasitology 2002 32 11 1389 1398 (Pubitemid 35279178)
45. Inaba T., Sato H., Kamiya H., Monoclonal IgA antibody-mediated expulsion of Trichinella from the intestine of mice Parasitology 2003 126 6 591 598 (Pubitemid 36791780)
46. Wilkes C. P., Bleay C., Paterson S., Viney M. E., The immune response during a Strongyloides ratti infection of rats Parasite Immunology 2007 29 7 339 346 (Pubitemid 46944444)
47. Yanming S., Ruofeng Y., Muleke C. I., Guangwei Z., Lixin X., Xiangrui L., Vaccination of goats with recombinant galectin antigen induces partial protection against Haemonchus contortus infection Parasite Immunology 2007 29 6 319 326 (Pubitemid 46800459)
48. Matsuzawa K., Abe M., Shirakura T., Zhao W. H., Nakamura F., Spontaneous worm expulsion and intestinal IgA response in mice infected by Vampirolepis nana Parasitology International 2008 57 4 512 514
49. Stear M. J., Bishop S. C., Doligalska M., Duncan J. L., Holmes P. H., Irvine J., McCririe L., McKellar Q. A., Sinski E., Murray M., Regulation of egg production, worm burden, worm length and worm fecundity by host responses in sheep infected with Ostertagia circumcincta Parasite Immunology 1995 17 12 643 652 (Pubitemid 26043094)
50. Lamm M. E., Interaction of antigens and antibodies at mucosal surfaces Annual Review of Microbiology 1997 51 311 340 (Pubitemid 27433052)
51. Roach T. I. A., Else K. J., Wakelin D., McLaren D. J., Grencis R. K., Trichuris muris: antigen recognition and transfer of immunity in mice by IgA monoclonal antibodies Parasite Immunology 1991 13 1 1 12
52. Smith W. D., Jackson F., Jackson E., Williams J., Age immunity to Ostertagia circumcincta: comparison of the local immune responses of 4 12 and 10-month-old lambs Journal of Comparative Pathology 1985 95 2 235 245 (Pubitemid 15093263)
53. Stear M. J., Bairden K., Innocent G. T., Mitchell S., Strain S. A. J., Bishop S. C., The relationship between IgA activity against fourth-stage larvae and density-dependent effects on the number of fourth-stage larvae of Teladorsagia circumcincta in naturally infected sheep Parasitology 2004 129 363 369 (Pubitemid 39265617)
54. Halliday A. M., Routledge C. M., Smith S. K., Matthews J. B., Smith W. D., Parasite loss and inhibited development of Teladorsagia circumcincta in relation to the kinetics of the local IgA response in sheep Parasite Immunology 2007 29 8 425 434 (Pubitemid 47083928)
55. Dunsmore J. D., Retarded development of Ostertagia species in sheep Nature 1960 186 4729 986 987
56. Henderson N. G., Stear M. J., Eosinophil and IgA responses in sheep infected with Teladorsagia circumcincta Veterinary Immunology and Immunopathology 2006 112 1-2 62 66 (Pubitemid 43817198)
57. Strain S. A. J., Stear M. J., The influence of protein supplementation on the immune response to Haemonchus contortus Parasite Immunology 2001 23 10 527 531 (Pubitemid 32989537)
58. Amarante A. F. T., Bricarello P. A., Huntley J. F., Mazzolin L. P., Gomes J. C., Relationship of abomasal histology and parasite-specific immunoglobulin A with the resistance to Haemonchus contortus infection in three breeds of sheep Veterinary Parasitology 2005 128 1-2 99 107 (Pubitemid 40255879)
59. Martnez-Valladares M., Vara-Del Ro M. P., Cruz-Rojo M. A., Rojo-Vzquez F. A., Genetic resistance to Teladorsagia circumcincta: IgA and parameters at slaughter in Churra sheep Parasite Immunology 2005 27 6 213 218 (Pubitemid 41113488)
60. Strain S. A. J., Bishop S. C., Henderson N. G., Kerr A., McKellar Q. A., Mitchell S., Stear M. J., The genetic control of IgA activity against Teladorsagia circumcincta and its association with parasite resistance in naturally infected sheep Parasitology 2002 124 5 545 552 (Pubitemid 34522871)
61. Sinski E., Bairden K., Duncan J. L., Eisler M. C., Holmes P. H., McKellar Q. A., Murray M., Stear M. J., Local and plasma antibody responses to the parasitic larval stages of the abomasal nematode Ostertagia circumcincta Veterinary Parasitology 1995 59 2 107 118
62. Paterson S., Viney M. E., Host immune responses are necessary for density dependence in nematode infections Parasitology 2002 125 3 283 292
63. Chandler A. C., Experiments on resistance of rats to superinfection with the nematode, Nippostrongylus muris American Journal of Epidemiology 1932 16 3 750 782
64. Chandler A. C., Studies on the nature of immunity to intestinal helminths. I. The local nature of the immunity of white rats to Nippostrongylus infection American Journal of Epidemiology 1935 22 157 168
65. Chandler A. C., Studies on the nature of immunity to intestinal helminths. II. A study of the correlation between degree of resistance of white rats to Nippostrongylus and interval between infections American Journal of Epidemiology 1935 22 243 256
66. Chandler A. C., Studies on the nature of immunity to intestinal helminths. III. Renewal of growth and egg production in Nippostrongylus after transfer from immune to non-immune rats American Journal of Epidemiology 1936 23 46 54
67. Chandler A. C., Studies on the nature of immunity to intestinal helminths. IV. The inter-relationships between parenteral and intestinal immunity in rats infected with Nippostrongylus American Journal of Epidemiology 1936 24 129 144
68. Knox D. P., Redmond D. L., Newlands G. F., Skuce P. J., Pettit D., Smith W. D., The nature and prospects for gut membrane proteins as vaccine candidates for Haemonchus contortus and other ruminant trichostrongyloids International Journal for Parasitology 2003 33 11 1129 1137 (Pubitemid 37101461)
69. Ekoja S. e., Smith W. D., Antibodies from sheep immunized against Haemonchus contortus with H-gal-GP inhibit the haemoglobinase activity of this protase complex Parasite Immunology 2010 32 731 738
70. Bowles V. M., Brandon M. R., Meeusen E., Characterization of local antibody responses to the gastrointestinal parasite Haemonchus contortus Immunology 1995 84 4 669 674
71. Schallig H. D. F. H., Van Leeuwen M. A. W., Hendrikx W. M. L., Isotype-specific serum antibody responses of sheep to Haemonchus contortus antigens Veterinary Parasitology 1995 56 1-3 149 162
72. Gmez-Muoz M. T., Cuquerella M., Gmez-Iglesias L. A., Mndez S., Fernndez-Prez F. J., De La Fuente C., Alunda J. M., Serum antibody response of Castellana sheep to Haemonchus contortus infection and challenge: relationship to abomasal worm burdens Veterinary Parasitology 1999 81 4 281 293 (Pubitemid 29123925)
73. Hertzberg H., Schallig H. D. F. H., Deplazes P., Development of a protective immunity against Ostertagia leptospicularis in trickle-infected sheep and parallel changes of serum gastrin, pepsinogen and antibody levels Veterinary Journal 1999 157 2 148 159 (Pubitemid 29141351)
74. Murray M., Miller H. R. P., Jarrett W. F. H., The globule leukocyte and its derivation from the subepithelial mast cell Laboratory Investigation 1968 19 222 234
75. Huntley J. F., McGorum B., Newlands G. F. J., Miller H. R. P., Granulated intraepithelial lymphocytes: their relationship to mucosal mast cells and globule leucocytes in the rat Immunology 1984 53 3 525 535 (Pubitemid 14020559)
76. Van Egmond M., Damen C. A., Van Spriel A. B., Vidarsson G., Van Garderen E., Van De Winkel J. G. J., IgA and the IgA Fc receptor Trends in Immunology 2001 22 4 205 211 (Pubitemid 32673660)
77. Woof J. M., Ken M. A., The function of immunoglobulin A in immunity Journal of Pathology 2006 208 2 270 282 (Pubitemid 43126119)
78. Prussin C., Metcalfe D. D., IgE, mast cells, basophils, and eosinophils Journal of Allergy and Clinical Immunology 2003 111 2 S486 S494
79. De Andres B., Rakasz E., Hagen M., McCormik M. L., Mueller A. L., Elliot D., Metwali A., Sandor M., Britigan B. E., Weinstock J. V., Lynch R. G., Lack of Fc- receptors on murine eosinophils: implications for the functional significance of elevated IgE and eosinophils in parasitic infections Blood 1997 89 10 3826 3836 (Pubitemid 27227108)
80. Behm C. A., Ovington K. S., The role of eosinophils in parasitic helminth infections: insights from genetically modified mice Parasitology Today 2000 16 5 202 209 (Pubitemid 30216566)
81. Lawrence C. E., Is there a common mechanism of gastrointestinal nematode expulsion? Parasite Immunology 2003 25 5 271 281 (Pubitemid 38021457)
82. Schallig H. D. F. H., Van Leeuwen M. A. W., Cornelissen A. W. C. A., Protective immunity induced by vaccination with two Haemonchus contortus excretory secretory proteins in sheep Parasite Immunology 1997 19 10 447 453 (Pubitemid 27472924)
83. Schallig H. D. F. H., Immunological responses of sheep to Haemonchus contortus Parasitology 2000 120 S63 S72
84. Huntley J. F., Redmond J., Welfare W., Brennan G., Jackson F., Kooyman F., Vervelde L., Studies on the immunoglobulin E responses to Teladorsagia circumcincta in sheep: purification of a major high molecular weight allergen Parasite Immunology 2001 23 5 227 235 (Pubitemid 34205679)
85. Pernthaner A., Cole S. A., Morrison L., Hein W. R., Increased expression of interleukin-5 (IL-5), IL-13, and tumor necrosis factor alpha genes in intestinal lymph cells of sheep selected for enhanced resistance to nematodes during infection with Trichostrongylus colubriformis Infection and Immunity 2005 73 4 2175 2183 (Pubitemid 40470817)
86. Pernthaner A., Shaw R. J., McNeill M. M., Morrison L., Hein W. R., Total and nematode-specific IgE responses in intestinal lymph of genetically resistant and susceptible sheep during infection with Trichostrongylus colubriformis Veterinary Immunology and Immunopathology 2005 104 1-2 69 80 (Pubitemid 40127442)
87. Murphy L., Eckersall P. D., Bishop S. C., Pettit J. J., Huntley J. F., Burchmore R., Stear M. J., Genetic variation among lambs in peripheral IgE activity against the larval stages of Teladorsagia circumcincta Parasitology 2010 1 12
88. Shaw R. J., McNeill M. M., Maass D. R., Hein W. R., Barber T. K., Wheeler M., Morris C. A., Shoemaker C. B., Identification and characterisation of an aspartyl protease inhibitor homologue as a major allergen of Trichostrongylus colubriformis International Journal for Parasitology 2003 33 11 1233 1243 (Pubitemid 37101469)
89. Bisset S. A., Vlassoff A., Morris C. A., Southey B. R., Baker R. L., Parker A. G. H., Heritability of and genetic correlations among faecal egg counts and productivity traits in Romney sheep New Zealand Journal of Agricultural Research 1992 35 51 58
90. Stear M. J., Hetzel D. J. S., Brown S. C., Gershwin L. J., Mackinnon M. J., Nicholas F. W., The relationships among ecto- and endoparasite levels, Class I antigens of the bovine major histocompatibility system, immunoglobulin E levels and weight gain Veterinary Parasitology 1990 34 4 303 321 (Pubitemid 20099802)
91. Stear M. J., Murray M., Genetic resistance to parasitic disease: particularly of resistance in ruminants to gastrointestinal nematodes Veterinary Parasitology 1994 54 13 161 176 (Pubitemid 24294203)
92. Stear M. J., Fitton L., Innocent G. T., Murphy L., Rennie K., Matthews L., The dynamic influence of genetic variation on the susceptibility of sheep to gastrointestinal nematode infection Journal of the Royal Society Interface 2007 4 16 767 776 (Pubitemid 47523484)
93. Bishop S. C., Jackson F., Coop R. L., Stear M. J., Genetic parameters for resistance to nematode infections in Texel lambs and their utility in breeding programmes Animal Science 2004 78 2 185 194 (Pubitemid 38517077)
94. Stear M. J., Bairden K., Bishop S. C., Buitkamp J., Duncan J. L., Gettinby G., Mckellar Q. A., Park M., Parkins J. J., Reid S. W. J., Strain S., Murray M., The genetic basis of resistance to Ostertagia circumcincta in lambs Veterinary Journal 1997 154 2 111 119 (Pubitemid 127703013)
95. Stear M. J., Bishop S. C., Mallard B. A., Raadsma H., The sustainability, feasibility and desirability of breeding livestock for disease resistance Research in Veterinary Science 2001 71 1 1 7 (Pubitemid 33100036)
96. Stear M. J., Innocent G. T., Buitkamp J., The evolution and maintenance of polymorphism in the major histocompatibility complex Veterinary Immunology and Immunopathology 2005 108 1-2 53 57 (Pubitemid 41317066)
97. Stear M. J., Tierney T. J., Baldock F. C., Brown S. C., Nicholas F. W., Rudder T. H., Class I antigens of the bovine major histocompatibility system are weakly associated with variation in faecal worm egg counts in naturally infected cattle Animal Genetics 1988 19 2 115 122
98. Gasbarre L. C., Leighton E. A., Davies C. J., Influence of host genetics upon antibody responses against gastrointestinal nematode infections in cattle Veterinary Parasitology 1993 46 1-4 81 91
99. Beh K. J., Hulme D. J., Callaghan M. J., Leish Z., Lenane I., Windon R. G., Maddox J. F., A genome scan for quantitative trait loci affecting resistance to Trichostrongylus colubriformis in sheep Animal Genetics 2002 33 2 97 106 (Pubitemid 34293984)
100. Crawford A. M., Paterson K. A., Dodds K. G., Tascon C. D., Williamson P. A., Thomson M. R., Bisset S. A., Beattie A. E., Greer G. J., Green R. S., Wheeler R., Shaw R. J., Knowler K., McEwan J. C., Discovery of quantitative trait loci for resistance to parasitic nematode infection in sheep: I. Analysis of outcross pedigrees BMC Genomics 2006 7, article 178
101. Marshall K., Maddox J. F., Lee S. H., Zhang Y., Kahn L., Graser H. U., Gondro C., Walkden-Brown S. W., Van Der Werf J. H. J., Genetic mapping of quantitative trait loci for resistance to Haemonchus contortus in sheep Animal Genetics 2009 40 3 262 272
102. Wilton A. N., Cobain T. J., Dawkins R. L., Family studies of IgA deficiency Immunogenetics 1985 21 4 333 342 (Pubitemid 15025830)
103. Schaffer F. M., Palermos J., Zhu Z. B., Barger B. O., Cooper M. D., Volanakis J. E., Individuals with IgA deficiency and common variable immunodeficiency share polymorphisms of major histocompatibility complex class III genes Proceedings of the National Academy of Sciences of the United States of America 1989 86 20 8015 8019 (Pubitemid 19265310)
104. Reil A., Bein G., Machulla H. K. G., Sternberg B., Seyfarth M., High-resolution DNA typing in immunoglobulin A deficiency confirms a positive association with DRB10301, DQB102 haplotypes Tissue Antigens 1997 50 5 501 506 (Pubitemid 27458273)
105. Schroeder H. W., Zhu Z. B., March R. E., Campbell R. D., Berney S. M., Nedospasov S. A., Turetskaya R. L., Atkinson T. P., Go R. C. P., Cooper M. D., Volanakis J. E., Susceptibility locus for IgA deficiency and common variable immunodeficiency in the HLA-DR3, -B8, -A1 haplotypes Molecular Medicine 1998 4 2 72 86 (Pubitemid 28223947)
106. Cucca F., Zhu Z. B., Khanna A., Cossu F., Congia M., Badiali M., Lampis R., Frau F., De Virgiliis S., Cao A., Arnone M., Piras P., Campbell R. D., Cooper M. D., Volanakis J. E., Powis S. H., Evaluation of IgA deficiency in Sardinians indicates a susceptibility gene is encoded within the HLA class III region Clinical and Experimental Immunology 1998 111 1 76 80 (Pubitemid 28062780)
107. Matthews V. B., Witt C. S., French M. A. H., Machulla H. K. G., De La Concha E. G., Cheong K. Y., Vigil P., Hollingsworth P. N., Warr K. J., Christiansen F. T., Price P., Central MHC genes affect IgA levels in the human: reciprocal effects in IgA deficiency and IgA nephropathy Human Immunology 2002 63 5 424 433 (Pubitemid 34525076)
108. Volanakis J. E., Zhu Z. B., Schaffer F. M., Macon K. J., Palermos J., Barger B. O., Go R., Campbell R. D., Schroeder H. W., Cooper M. D., Major histocompatibility complex class III genes and susceptibility to immunoglobulin A deficiency and common variable immunodeficiency Journal of Clinical Investigation 1992 89 6 1914 1922
109. Olerup O., Smith C. I. E., Bjorkander J., Hammarstrom L., Shared HLA class II-associated genetic susceptibility and resistance, related to the HLA-DQB1 gene, in IgA deficiency and common variable immunodeficiency Proceedings of the National Academy of Sciences of the United States of America 1992 89 22 10653 10657
110. Voechovsk I., Cullen M., Carrington M., Hammarstrm L., Webster A. D. B., Fine mapping of IGAD1 in IgA deficiency and common variable immunodeficiency: identification and characterization of haplotypes shared by affected members of 101 multiple-case families Journal of Immunology 2000 164 8 4408 4416 (Pubitemid 30215105)
111. Kralovicova J., Hammarstrm L., Plebani A., Webster A. D. B., Vorechovsky I., Fine-scale mapping at IGAD1 and genome-wide genetic linkage analysis implicate HLA-DQ/DR as a major susceptibility locus in selective IgA deficiency and common variable immunodeficiency Journal of Immunology 2003 170 5 2765 2775 (Pubitemid 36245672)
112. Sekine H., Ferreira R. C., Pan-Hammarstrm Q., Graham R. R., Ziemba B., De Vries S. S., Liu J., Hippen K., Koeuth T., Ortmann W., Iwahori A., Elliott M. K., Offer S., Skon C., Du L., Novitzke J., Lee A. T., Zhao N., Tompkins J. D., Altshuler D., Gregersen P. K., Cunningham-Rundles C., Harris R. S., Her C., Nelson D. L., Hammarstrm L., Gilkeson G. S., Behrens T. W., Role for Msh5 in the regulation of Ig class switch recombination Proceedings of the National Academy of Sciences of the United States of America 2007 104 17 7193 7198 (Pubitemid 47186031)
113. Harfe B. D., Jinks-Robertson S., DNA mismatch repair and genetic instability Annual Review of Genetics 2000 34 359 399 (Pubitemid 32065926)
114. Surtees J. A., Argueso J. L., Alani E., Mismatch repair proteins: key regulators of genetic recombination Cytogenetic and Genome Research 2004 107 3-4 146 159 (Pubitemid 39370377)
115. Guikema J. E. J., Schrader C. E., Leus N. G. J., Ucher A., Linehan E. K., Werling U., Edelmann W., Stavnezer J., Reassessment of the role of Mut S homolog 5 in Ig class switch recombination shows lack of involvement in cis- and trans-switching Journal of Immunology 2008 181 12 8450 8459
116. Offer S. M., Pan-Hammarstrm Q., Hammarstrm L., Harris R. S., Unique DNA repair gene variations and potential associations with the primary antibody deficiency syndromes igAD and CVID PLoS ONE 2010 5 8
117. Pozo N. D., Medrano L. M., Cnit M. C., Fernndez-Arquero M., Ferreira A., Garca-Rodrguez M. C., de la Concha E. G., Urcelay E., Nez C., MSH5 is not a genetic predisposing factor for immunoglobulin A deficiency but marks the HLA-DRB10102 subgroup carrying susceptibility Human Immunology 2010 71 861 864
118. Wassom D. L., Kelly E. A. B., The role of the major histocompatibility complex in resistance to parasite infections Critical Reviews in Immunology 1990 10 1 31 52 (Pubitemid 20074274)
119. Kennedy M. W., Genetic control of the immune repertoire in nematode infections Parasitology Today 1989 5 10 316 324 (Pubitemid 19246975)
120. Dainichi T., Maekawa Y., Ishii K., Zhang T., Fawzy Nashed B., Sakai T., Takashima M., Himeno K., Nippocystatin, a cysteine protease inhibitor from Nippostrongylus brasiliensis, inhibits antigen processing and modulates antigen-specific immune response Infection and Immunity 2001 69 12 7380 7386 (Pubitemid 33086562)
121. Knight J. S., Baird D. B., Hein W. R., Pernthaner A., The gastrointestinal nmatode Tricostrongylus colubriformis down-regulates immune gene expression in migratory cells in afferent lymph BMC Immunology 2010 11, article 51
122. Wassom D. L., Krco C. J., David C. S., I-E expression and susceptibility to parasite infection Immunology Today 1987 8 2 39 43 (Pubitemid 17034657)
123. Keane O. M., Zadissa A., Wilson T., Hyndman D. L., Greer G. J., Baird D. B., McCulloch A. F., Crawford A. M., McEwan J. C., Gene expression profiling of Nave sheep genetically resistant and susceptible to gastrointestinal nematodes BMC Genomics 2006 7, article 42
124. Charbonnel N., Pemberton J., A long-term genetic survey of an ungulate population reveals balancing selection acting on MHC through spatial and temporal fluctuations in selection Heredity 2005 95 5 377 388 (Pubitemid 41548413)
125. Paterson S., Evidence for balancing selection at the major histocompatibility complex in a free-living ruminant Journal of Heredity 1998 89 4 289 294 (Pubitemid 28366920)
126. Beraldi D., McRae A. F., Gratten J., Pilkington J. G., Slate J., Visscher P. M., Pemberton J. M., Quantitative trait loci (QTL) mapping of resistance to strongyles and coccidia in the free-living Soay sheep (Ovis aries) International Journal for Parasitology 2007 37 1 121 129 (Pubitemid 44958561)