Is the decline of desert bighorn sheep from infectious disease the result of low MHC variation?

Heredity

Volumn 86, Issue 4, 2001, Pages 439-450

  Gutierrez Espeleta, Gustavo A ^a   Hedrick, Philip W ^a   Kalinowski, Steven T ^a   Garrigan, Daniel ^a   Boyce, Walter M ^b  

^a ARIZONA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adaptive variation; Heterozygosity; Phylogenetic tree; Substitution rate; Trans species polymorphism

Indexed keywords

AMINO ACID SUBSTITUTION; BINDING SITE; BREED; EUROPE; GENETIC POLYMORPHISM; GENETIC SELECTION; GENETIC SUSCEPTIBILITY; GENETIC VARIANCE; HERITABILITY; IMMUNE SYSTEM; MAJOR HISTOCOMPATIBILITY COMPLEX; NUCLEOTIDE SEQUENCE; POPULATION DYNAMICS; SHEEP;

DISEASE; GENETIC VARIATION; IMMUNOCOMPETENCE; POPULATION DECLINE;

AMINO ACID SEQUENCE; ANIMALS; ANIMALS, WILD; GENES, MHC CLASS II; HLA-D ANTIGENS; INFECTION; MICROSATELLITE REPEATS; MOLECULAR SEQUENCE DATA; POLYMORPHISM, GENETIC; POPULATION DYNAMICS; SEQUENCE ALIGNMENT; SHEEP; SHEEP DISEASES; VARIATION (GENETICS);

NORTH AMERICA;

BISON; BOS TAURUS; BOVIDAE; CAPRA HIRCUS; CERVIDAE; MAMMALIA; OVIS ARIES; OVIS CANADENSIS; VERTEBRATA;

EID: 0034887645     PISSN: 0018067X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2540.2001.00853.x     Document Type: Article

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