Evidence for balancing selection at the major histocompatibility complex in a free-living ruminant

Journal of Heredity

Volumn 89, Issue 4, 1998, Pages 289-294

  Paterson, S ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; BIODIVERSITY; BOVIDS; DNA FLANKING REGION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; IMMUNE RESPONSE; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ALLELES; ANIMALS; BASE SEQUENCE; DNA, COMPLEMENTARY; EXONS; GENES, MHC CLASS II; LINKAGE DISEQUILIBRIUM; MICROSATELLITE REPEATS; MOLECULAR SEQUENCE DATA; RUMINANTS; SELECTION (GENETICS); SEQUENCE HOMOLOGY, NUCLEIC ACID; SHEEP; VARIATION (GENETICS);

ANIMALIA; BOVIDAE; OVIS; OVIS ARIES;

EID: 0031815254     PISSN: 00221503     EISSN: None     Source Type: Journal    
DOI: 10.1093/jhered/89.4.289     Document Type: Article

References (45)

1. Allison AC, 1964 Polymorphism and natural selection in human populations. Cold Spring Harbor Symp Quant Biol 29:139-149.
2. Ammer H, Schwaiger FW, Kammerbauer C, Gomolka M, Arriens A, Lazary S, and Epplen JT, 1992. Exonic polymorphism versus intronic simple repeat hypervariability in MHC-DRB-genes. Immunogenetics 32:330-337.
3. Benacerraf B. 1981 Role of MHC gene products in immune regulation. Science 212:1229-1238.
4. Bishop JA, 1981 A neo-Darwinian approach to resistance: examples from mammals. In: Genetic consequences of man-made change (Bishop JA and Cook LM, eds).New York: Academic Press.
5. Bishop MD, Kappes SM, Keele JW, Stone RT, Sunden SLF, Hawkins GA, Toldo SS, Fries R, Grosz MD, Yoo JY, and Beattie CW, 1994. A genetic-linkage map for cattle. Genetics 136:619-639.
6. Blattman AN and Beh KJ, 1992. Dinucleotide repeat polymorphism within the ovine major histocompatibility complex. Anim Genet 23:392.
7. Brown JH, Jardetzky T, Gorga JC, Stern LJ, Strominger JL, and Wiley DC, 1993a. Crystal-structure of the class-II histocompatibility antigen HLA-DR1. J Cell Biochem 517:66-66.
8. Brown JH, Jardetzky TS, Gorga JC, Stern LJ, Urban RG, Strominger JL, and Wiley DC, 1993b. 3-dimensional structure of the human class-II histocompatibility antigen HLA-DR1. Nature 364:33-39.
9. Brown JH, Jardetzky T, Saper MA, Samraoui B, Bjorkman PJ, and Wiley DC, 1988. A hypothetical model of the foreign antigen site of class II histocompatibility molecules. Nature 332:845-850.
10. Bruford MW and Wayne RK, 1993. Microsatellites and their application to population genetic studies. Curr Opin Genet Dev 3:939-943.
11. Clutton-Brock TH, Price OF, Albon SD, and Jewell PA, 1991. Persistent instability and population regulation in Soay sheep. J Anim Ecol 60:593-608.
12. Clutton-Brock TH, Price OF, Albon SD, and Jewell PA, 1992. Early development and population fluctuations in Soay sheep. J Anim Ecol 61:381-396.
13. Crawford AM, Dodds KG, Ede AJ, Pierson CA, Montgomery GW, Garmonsway HG, Beattie AE, Davies K, Maddox JF, Kappes SW, Stone RT, Nguyen TC, Penty JM, Lord EA, Broom JE, Buitkamp J, Schwaiger W. Epplen JT, Matthew P, Matthews ME, Hulme DJ, Beh KJ, McGraw RA, and Beattie CW, 1995. An autosomal genetic-linkage map of the sheep genome. Genetics 140:703-724.
14. Doherty PC and Zinkernagel RM, 1975. Enhanced immunological surveillance in mice heterozygous at the H-2 gene complex. Nature 256:50-52.
15. Groth DM and Wetherall JD, 1994. Dinucleotide repeat polymorphism within the ovine major histocompatibility complex class I region. Anim Genet 25:61.
16. Guo SW and Thompson EA, 1992. Performing the exact test of Hardy-Weinberg proportion for multiple alleles. Biometrics 48:361-372.
17. Hamilton WD, 1980. Sex versus non-sex versus parasite. Oikos 35:282-290.
18. Hedrick PW, 1994. Evolutionary genetics of the major histocompatibility complex. Am Nat 143:945-964.
19. Hedrick PW and Thomson G, 1983. Evidence for balancing selection at HLA. Genetics 104:449-456.
20. Hill AVS, Allsopp CEM, Kwiatkowski D, Anstey NM, Twumasi P, Rowe PA, Bennett S, Brewster D, McMichael AJ, and Greenwood BM, 1991. Common West African HLA antigens are associated with protection from severe malaria. Nature 352:595-600.
21. Hughes AL, Hughes MK, Howell CY, and Nei M, 1994. Natural selection at the class II major histocompatibility complex loci of mammals. Phil Trans R Soc Lond B 345:359-367.
22. Hughes AL and Nei M, 1988. Pattern of nucleotide substitution at major histocompatibility complex class-I loci reveals overdominant selection. Nature 335:167-170.
23. Hughes AL and Nei M, 1989. Nucleotide substitution at major histocompatibiuty complex class-II loci - evidence for overdominant selection. Proc Natl Acad Sci USA 86:958-962.
24. Jewell PA, Milner C, and Morton Boyd J, 1974. Island survivors. London: Athlone Press.
25. Jones JS, Leith BH, and Rawlings P, 1977. Polymorphism in Cepea: a problem with too many solutions. Annu Rev Ecol Systemat 8:109-143.
26. Klein J, 1986. Natural history of the major histocompatibility complex. New York: John Wiley.
27. Klein J, Satta Y, Ohuigin C, and Takahata N, 1993a. The molecular descent of the major histocompatibility complex. Annu Rev Immunol 11:269-295.
28. Klein J, Takahata N, and Ayala FJ, 1993b. MHC polymorphism and human origins. Sci Am 269:78-83.
29. Kumar S, Tamura K, and Nei M, 1993. MEGA: molecular evolutionary genetic analysis. University Park, Pennsylvania: Pennsylvania State University; 11-12.
30. Mikko S and Andersson L, 1995a. Extensive MHC class II diversity in African and European cattle, Immunogenetics 42:408-413
31. Mikko S and Andersson L, 1995b. Low major histocompatibility complex class II diversity in European and North American moose. Proc Natl Acad Sci USA 92: 4259-4263.
32. Mikko S, Spencer M, Morris B, Stabile S, Basu T, Stormont C, and Andersson L, 1997. A comparative analysis of MHC DRB3 polymorphism in the American bison (Bison bison). J Hered 88:499-503.
33. Ohta T, 1982. Linkage disequilibrium due to random genetic drift in finite subdivided populations. Proc Natl Acad Sci USA 79:1940-1944.
34. Pemberton JM, Smith JA, Coulson TN, Marshall TC, Slate J, Paterson S, Albon SD, and Clutton-Brock TH, 1996. The maintenance of genetic polymorphism in small island populations: large mammals in the Hebrides. Phil Trans R Soc Lond B 351:745-752.
35. Potts WK, Manning CJ, and Wakeland EK, 1991. Mating patterns in seminatural populations of mice influenced by MHC genotype. Nature 352:619-621.
36. Potts WK, Manning CJ, and Wakeland EK, 1994. The role of infectious-disease, inbreeding and mating preferences in maintaining MHC genetic diversity - an experimental test. Phil Trans R Soc Lond B 346:369-378.
37. Raymond M and Rousset F, 1995. Genepop (version 1.2) - population genetics software for exact tests and ecumenicism. J Hered 86:248-249.
38. Sambrook J, Fritsch EF, and Maniatis T, 1989. Molecular cloning: a laboratory manual. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press.
39. Schwaiger FW, Buitkamp J, Weyers E, and Epplen JT, 1993a. Typing of artiodactyl MHC genes with the help of intronic simple repeated sequences. Mol Ecol 2:55-59.
40. Schwaiger FW, Weyers E, Buitkamp J, Ede AJ, Crawford A, and Epplen JT, 1994. Interdependent MHC-DRB exonplus-intron evolution in artiodactyls. Mol Biol Evol 11: 239-249.
41. Schwaiger FW, Weyers E, Epplen C, Brun J, Ruff G, Crawford A, and Epplen JT, 1993b. The paradox of MHC-DRB exon-intron evolution - alpha-helix and beta-sheet encoding regions diverge while hypervariable intronic simple repeats coevolve with beta-sheet codons. J Mol Evol 37:260-272.
42. van Delden W, 1982. The alcohol dehydrogenase polymorphism in Drosophila melanogaster. selection at an enzyme locus. Evol Biol 15:187-222.
43. Watterson GA, 1978. The homozygosity test of neutrality. Genetics 88:405-417.
44. Weir DW and Stewart J, 1993. Immunology. Edinburgh: Churchill Livingston.
45. Yuhki N and O'Brien SJ, 1997. Nature and origin of polymorphism in feline MHC class II DRA and DRB genes. J Immunol 158:2822-2833.