Genetic mapping of quantitative trait loci for resistance to haemonchus contortus in sheep

Animal Genetics

Volumn 40, Issue 3, 2009, Pages 262-272

  Marshall, K ^a,c   Maddox, J F ^b   Lee, S H ^a   Zhang, Y ^a   Kahn, L ^a   Graser, H U ^a   Gondro, C ^a   Walkden Brown, S W ^a   Van Der Werf, J H J ^a  

^a UNIVERSITY OF NEW ENGLAND   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c INTERNATIONAL LIVESTOCK RESEARCH INSTITUTE   (Kenya)

Author keywords

Disease resistance; Genome scan; Haemonchus contortus; Linkage analysis; Linkage disequilibrium linkage analysis; Nematodes; Quantitative trait loci; Sheep

Indexed keywords

ANIMAL; ANIMAL DISEASE; ARTICLE; BREEDING; CHROMOSOME MAP; FECES; FEMALE; GASTROINTESTINAL DISEASE; GENETIC ASSOCIATION; GENETIC MARKER; GENETICS; GENOTYPE; HAEMONCHOSIS; HAEMONCHUS; IMMUNOLOGY; INNATE IMMUNITY; MALE; PARASITE IDENTIFICATION; PARASITOLOGY; PEDIGREE; QUANTITATIVE TRAIT LOCUS; SHEEP; SHEEP DISEASE;

ANIMALS; BREEDING; CHROMOSOME MAPPING; FECES; FEMALE; GASTROINTESTINAL DISEASES; GENETIC MARKERS; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HAEMONCHIASIS; HAEMONCHUS; IMMUNITY, INNATE; MALE; PARASITE EGG COUNT; PEDIGREE; QUANTITATIVE TRAIT LOCI; SHEEP; SHEEP DISEASES;

ANIMALIA; HAEMONCHUS CONTORTUS; NEMATODA; OVIS ARIES;

EID: 65649119717     PISSN: 02689146     EISSN: 13652052     Source Type: Journal    
DOI: 10.1111/j.1365-2052.2008.01836.x     Document Type: Article

References (45)

1. Albers G.A.A., Gray G.D., Piper L.R., Barker J.S.F., Le Jambre L.F. Barger I.A. (1987) The genetics of resistance and resilience to Haemonchus contortus infection in young merino sheep. International Journal of Parasitology 17, 1355 63. (Pubitemid 18013491)
2. Beh K.J., Hulme D.J., Callaghan M.J., Leish Z., Lenane I., Windon R.G. Maddox J.F. (2002) A genome scan for quantitative trait loci affecting resistance to Trichostrongylus colubriformis in sheep. Animal Genetics 33, 97 106. (Pubitemid 34293984)
3. Besier B. (2007) New anthelmintics for livestock: the time is right. Trends in Parasitology 23, 21 4.
4. Besier R.B. Love S.C.J. (2003) Anthelmintic resistance in sheep nematodes in Australia: the need for new approaches. Australian Journal for Experimental Agriculture 43, 1383 91. (Pubitemid 38171150)
5. Bisset S.A., Vlassnoff A., Douch P.G.C., Jonas W.E., West C.J. Green R.S. (1996) Nematode burdens and immunological responses following natural challenge in Romney lambs selectively bred for low or high faecal worm egg count. Veterinary Parasitology 61, 249 63. (Pubitemid 26027810)
6. Brown D.J., Huisman A.E., Swan A.A., Graser H.-U., Woolaston R.R., Ball A.J., Atkins K.D. Banks R.G. (2007) Genetic evaluation for the Australian sheep industry. Proceedings of the Association for the Advancement of Animal Breeding and Genetics 17, 187 94.
7. Cabaret J., Gasnier N. Jacquiet P. (1998) Faecal egg counts are representative of digestive-tract strongyle worm burdens in sheep and goats. Parasite 5, 137 42. (Pubitemid 128505051)
8. Churchill G.A. Doerge R.W. (1994) Empirical threshold values for quantitative trait loci mapping. Genetics 138, 963 71. (Pubitemid 24337818)
9. Coadwell W.J. Ward P.F. (1982) The use of faecal egg counts for estimating worm burdens in sheep infected with Haemonchus contortus. Parasitology 85, 251 6.
10. Crawford A.M., Paterson K.A., Dodds K.G. et al. (2006) Discovery of quantitative trait loci for resistance to parasitic nematode infection in sheep: I. Analysis of outcross pedigrees. BMC Genomics 7, 178 88. (Pubitemid 44468440)
11. Davies G., Stear M.J., Benothman M., Abuagob O., Kerr A., Mitchell S. Bishop S.C. (2006) Quantitative trait loci associated with parasitic infection in Scottish blackface sheep. Heredity 96, 252 8. (Pubitemid 43307941)
12. Feenstra B. Skovgaard I.M. (2004) A quantitative trait locus mixture model that avoids spurious LOD score peaks. Genetics 167, 959 65. (Pubitemid 38931880)
13. Georges M. Massey J. (1992) Polymorphic DNA Markers in Bovidae (World Intellectual Property Org., Geneva). WO Publication No 92/13102.
14. Gilmour A.R., Gogel B.J., Cullis B.R., Welham S.J. Thompson R. (2002) asreml User Guide Release 1.0. VSN International Ltd, Hemel Hempstead, UK.
15. Gray G.D., Woolaston R.R. Eaton B.T. (1995) Breeding for Resistance to Infectious Disease in Small Ruminants. Australian Center for International Agricultural Research (ACIAR) Monograph Series No. 34, Canberra.
16. Green P., Falls K. Crooks S. (1990) Documentation for cri-map, Version 2.4. Washington University of School of Medicine, St Louis, MO.
17. Henshall J.M. Goddard M.E. (1999) Multiple-trait mapping of quantitative trait loci after selective genotyping using logistic regression. Genetics 151, 885 94. (Pubitemid 29082952)
18. Kaplan R.M. (2004) Drug resistance in nematodes of veterinary importance: a status report. Trends in Parasitology 20, 477 81. (Pubitemid 39195057)
19. Kerr R.J. Henshall J.M. (2001) Composite interval mapping in half-sib analysis. Proceedings of the Association for the Advancement of Animal Breeding and Genetics 14, 401 4.
20. Kerr R.J., McLachlan G.M. Henshall J.M. (2005) Use of the EM algorithm to detect QTL affecting multiple-traits in an across half-sib family analysis. Genetics Selection and Evolution 37, 83 103. (Pubitemid 40078232)
21. Lander E.S. Botstein D. (1989) Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics 121, 185 99. (Pubitemid 19026331)
22. Lee S.H. van der Werf J.H.J. (2004) The efficiency of designs for fine-mapping of quantitative trait loci using combined linkage disequilibrium and linkage. Genetics Selection and Evolution 36, 145 61. (Pubitemid 38272283)
23. Lee S.H. van der Werf J.H.J. (2006a) Using dominance relationship coefficients based on linkage disequilibrium and linkage with a general complex pedigree to increase mapping resolution. Genetics 174, 1009 16. (Pubitemid 44656485)
24. Lee S.H. van der Werf J.H.J. (2006b) Simultaneous fine mapping of multiple closely linked quantitative trait loci using combined linkage disequilibrium and linkage with a general pedigree. Genetics 173, 2329 37. (Pubitemid 44285706)
25. Lee S.H. van der Werf J.H.J. (2006c) An efficient variance component approach implementing an average information REML suitable for combined LD and linkage mapping with a general complex pedigree. Genetics Selection and Evolution 38, 25 43. (Pubitemid 43075122)
26. Lee S.H., van der Werf J.H.J. Tier B. (2005) Combining the meiosis Gibbs sampler with the random walk approach for linkage and association studies with a general complex pedigree and multimarker loci. Genetics 171, 2063 72.
27. Lee S.H., van der Werf J.H.J. Kinghorn B.P. (2008) Using an evolutionary algorithm and parallel computing for haplotyping in a general complex pedigree with multiple marker loci. BMC Bioinformatics 9, 189.
28. Lord E., Davis G.H., Dodds K.G., Henry H.M., Lumsden J.M. Montgomery G.W. (1998) Identification of Booroola Carriers Using Microsatellite Markers. Proceedings of the 6th World Congress on Genetics Applied to Livestock Production 27, 19 22.
29. Love S.C.J., Neilson F.J.A., Biddle A.J. McKinnon R. (2003) Moxidectin-resistant Haemonchus contortus in sheep in northern New South Wales. Australian Veterinary Journal 81, 359 60. (Pubitemid 44139072)
30. Maddox J.F., Davies K.P., Crawford A.M. et al. (2001) An enhanced linkage map of the sheep genome comprising more than 1000 loci. Genome Research 11, 1275 89. (Pubitemid 32677303)
31. Marshall K., van der Werf J.H.J., Maddox J.F., Graser H.-U., Zhang Y., Walkden-Brown S.W. Kahn L. (2005) A genome scan for quantitative trait loci for resistance to the gastrointestinal parasite Haemonchus contortus in sheep. Proceedings of the Association for the Advancement of Animal Breeding and Genetics 16, 115 8.
32. Marshall K., Lee S.H., van der Werf J.H.J. (2006) Information sources in linkage disequilibrium - linkage mapping using half-sib designs. In : Proceedings of the 8th World Congress on Genetics Applied to Livestock Production, Comm. 21-09. Belo Horizonte, Brazil.
33. Meszaros S.A., Henshall J.M., Burgess S.K., Gray G.D. Tier B. (1999) Detection of a quantitative trait locus associated with a reduction in fecal egg count in merino sheep. Proceedings of the Association for the Advancement of Animal Breeding and Genetics 13, 211 4.
34. Meuwissen T.H.E. Goddard M.E. (2001) Prediction of identity by descent probabilities from marker-haplotypes. Genetics Selection and Evolution 33, 605 34. (Pubitemid 34072352)
35. Meuwissen T.H.E., Karlsen A., Lien S., Olsaker I. Goddard M.E. (2002) Fine mapping of a quantitative trait locus for twinning rate using combined linkage and linkage disequilibrium mapping. Genetics 161, 373 9. (Pubitemid 34564064)
36. Moreno C.R., Gruner L., Scala A. et al. (2006) QTL for Natural Resistance to Internal Parasites in two Designs Based on Natural and Experimental Conditions of Infection. In : Proceedings of the 8th World Congress on Genetics Applied to Livestock Production. Belo Horizonte, Brazil.
37. Morris C.A., Wheeler M., Watson T.G., Hosking B.C. Leathwick D.M. (2005) Direct and correlated responses to selection for high or low faecal nematode egg count in Perendale sheep. New Zealand Journal of Agricultural Research 48, 1 10. (Pubitemid 40670177)
38. Sackett D., Holmes P., Abbott K., Jephcott S. Barber M. (2006) Assessing the economic cost of endemic disease on the profitability of Australian beef cattle and sheep producers. Meat & Livestock Australia Ltd, North Sydney.
39. SAS (2004) SAS/STAT User's Guide. SAS Institute Inc., Cary, NC.
40. Sobel E. Lange K. (1996) Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics. The American Journal of Human Genetics 58, 1323 37. (Pubitemid 26153844)
41. Stear M.J., Bishop S.C., Doligalska M., Duncan J.L., Holmes P.H., Irvine J., McCririe L., McKellar Q.A., Sinski E. Murray M. (1995) Regulation of egg production, worm burden, worm length and worm fecundity by host responses in sheep infected with Ostertagia circumcincta. Parasite Immunology 17, 643 52. (Pubitemid 26043094)
42. Thompson E.A. Heath S.C. (1999) Estimation of conditional multilocus gene identity among relatives. In : Statistics in Molecular Biology and Genetics, IMS Lecture Notes (Ed. by F. Seillier-Moiseiwitsch pp. 95 113. Institute of Mathematical Statistics, American Mathematical Society, Providence, RI.
43. Visscher P.M., Thompson R. Haley C.S. (1996) Confidence intervals in QTL mapping by bootstrapping. Genetics 143, 1013 20. (Pubitemid 26001097)
44. Waghorn T.S., Leathwick D.M., Rhodes A.P., Lawrence K.E., Jackson R., Pomroy W.E., West D.M. Moffat J.R. (2006) Prevalence of anthelmintic resistance on sheep farms in New Zealand. New Zealand Veterinary Journal 54, 271 7. (Pubitemid 46064857)
45. Zeng Z.B. (1993) Theoretical basis for separation of multiple linked gene effects in mapping quantitative trait loci. Proceedings of the National Academy of Sciences of the United States of America 90, 10972 6.