Development of a protective immunity against Ostertagia leptospicularis in trickle-infected sheep and parallel changes of serum gastrin, pepsinogen and antibody levels

Veterinary Journal

Volumn 157, Issue 2, 1999, Pages 148-159

  Hertzberg, H ^a   Schallig, H D F H ^b   Deplazes, P ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Antibody; Gastrin; IgA; IgG1; IgG2; Immunity; Ostertagia; Pepsinogen; Protection; Sheep

Indexed keywords

ANTHELMINTIC AGENT; ANTIBODY; FENBENDAZOLE; GASTRIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; PARASITE ANTIGEN; PEPSINOGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY BLOOD LEVEL; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FECES ANALYSIS; GASTRIN BLOOD LEVEL; IMMUNE RESPONSE; NONHUMAN; OSTERTAGIA; PARASITE SURVIVAL; PROTEIN BLOOD LEVEL; PROVOCATION TEST; SHEEP DISEASE; WORM INFECTION;

ANIMALIA; OSTERTAGIA; OSTERTAGIA LEPTOSPICULARIS; OVIS ARIES;

EID: 0032995213     PISSN: 10900233     EISSN: None     Source Type: Journal    
DOI: 10.1053/tvjl.1998.0307     Document Type: Article

References (29)

1. ANDERSON, N. (1979). Trichostrongylid infections of sheep in a winter rainfall region. II. Epizootiological studies in the western district of Victoria, 1967-1968. Australian Journal of Agricultural Research 24, 599-611.
2. ANDERSON, N., HANSKY, J. & TITCHEN, D.A. (1981). Effects of Ostertagia circumcincta infections on plasma gastrin in sheep. Parasitology 82, 401-10.
3. ARMOUR, J., JARRETT, W.F.H. & JENNINGS, F.W. (1966). Experimental Ostertagia circumcincta infections in sheep: development and pathogenesis of a single infection. American Journal of Veterinary Research 27, 1267-78.
4. BERGHEN, P., DORNY, P. & VERCRUYSSE, J. (1987). Evaluation of a simplified blood pepsinogen assay. American Journal of Veterinary Research 48, 664-9.
5. CARAYANNOPOULOS, L. & CAPRA, J.D. (1993). Immunoglobulins. In Fundamental Immunology, ed. W. Paul, pp. 284-311. New York: Raven Press.
6. ENGVALL, E. & PERLMANN, P. (1972). Enzyme-linked immunosorbent assay, ELISA III. Journal of Immunology 109, 129-135.
7. GAMBLE, H.R. & ZAJAC, A.M. (1992). Resistance of St. Croix lambs to Haemonchus contortus in experimentally and naturally acquired infections. Veterinary Parasitology 41, 211-25.
8. GILL, H.S., GRAY, G.D. WATSON, D.L. & HUSBAND, A.J. (1993). Isotype-specific antibody responses to Haemonchus contortus in genetically resistant sheep. Parasite Immunology 15, 61-7.
9. GORDON, J., BURD, P. & GALLI, S. (1990). Mast cells as a source of multifunctional cytokines. Immunology Today 11, 458-64.
10. HERTZBERG, H., KOHLER, L., DEPLAZES, P., HÄCKI, W.H. & ECKERT, J. (1995). Pathophysiological studies of sheep during the build-up of immunity against Ostertagia leptospicularis and after a challenge infection. Research in Veterinary Science 58, 14-9.
11. HONG, C., MICHEL, J.F. & LANCASTER, M.B. (1989). Development of protection and of self-cure in lambs infected daily with Ostertagia circumcincta. Veterinary Parasitology 31, 125-31.
12. LAWTON, D.E.B., REYNOLDS, G.W., HODGKINSON, S.M., POMROY, W.E. & SIMPSON, H.V. (1996). Infection of sheep with adult and larval Ostertagia circumcincta: effects on abomasal pH and serum gastrin and pepsinogen. International Journal for Parasitology 26, 1063-74.
13. LEHMANN, F.S., GOLODNER, E.H., WANG, J.Y., CHEN, M.C.Y., AVEDIAN, D., CALAM, J., WALSH, J.H., et al. (1996). Mononuclear cells and cytokines stimulate gastrin release from canine antral cells in primary culture. American Journal of Physiology 33, G783-8.
14. MOSTOFA, M. & MCKELLAR, Q.A. (1989). Effect of an antimuscarinic drug on the plasma pepsinogen activity of sheep infected with Ostertagia circumcincta. Research in Veterinary Science 47, 208-11.
15. PARKER, T.O. (1977). Technical description, R. N. Powell, Scientific Instruments, Yenora, NSW, Australia.
16. POWERS, K.G., WOOD, I.B., ECKERT, J., GIBSON, T. & SMITH, H.J. (1982). World association for the advancement of veterinary parasitology (WAAVP) Guidelines for evaluating the efficacy of anthelmintics in ruminants (bovine and ovine). Veterinary Parasitology 10, 265-84.
17. REYNOLDS, G.W., SIMPSON, H.V., CARR, D.H. & MCLEAY, L.M. (1991). Gastrin: its molecular forms and secretion in sheep. In Physiological aspects of digestion and metabolism in ruminants, eds Tsuda T., Sasaki Y. & Kawastrima R., pp. 63-87. New York: Academic Press.
18. SCHALLIG, H.D.F.H. & VAN LEEUWEN, M.A.W. (1997). Protective immunity to the blood-feeding nematode Haemonchus contortus induced by vaccination with parasite low molecular weight antigens. Parasitology 114, 293-9.
19. SCHALLIG, H.D.F.H., VAN LEEUWEN, M.A.W. & HENDRIKX, W.M.L. (1995). Isotype-specific serum antibody responses of sheep to Haemonchus contortus antigens. Veterinary Parasitology 56, 149-62.
20. SCHMIDT, U. (1971). Parasitologische Kotuntersuchung durch ein neues Verdünnungsverfahren. Tierärztliche Umschau 26, 229-30.
21. SEATON, D.S., JACKSON, F., SMITH, W.D. & ANGUS, K.W. (1989). Development of immunity to incoming radio-labelled larvae in lambs continuously infected with Ostertagia circumcincta. Research in Veterinary Science 46, 241-6.
22. SMITH, W.D., JACKSON, F., JACKSON, E. & WILLIAMS, J. (1983). Local immunity and Ostertagia circumcincta: changes in the gastric lymph of immune sheep after a challenge infection. Journal of Comparative Pathology 93, 479-88.
23. SMITH, W.D., JACKSON, F., JACKSON, E., WILLIAMS, J. & MILLER, H.R.P. (1984). Manifestations of resistance to ovine ostertagiasis associated with immunological responses in the gastric lymph. Journal of Comparative Pathology 94, 591-601.
24. SULGER BÜEL, E., ECKERT, J., HÄCKI, W.H., HAUSER, B. & LUTZ, H. (1984). Pathogenität von Ostertagia leptospicularis für Rind und Schaf. Zentralblatt für Veterinärmedizin B 31, 189-202.
25. URQUHART, G.M., JARRETT, W.F., JENNINGS, F.W., MCLNTYRE, W.I., MULLIGAN, W & SHARP, N.C. (1966). Immunity to Haemonchus contortus infection. Failure of x-irradiated larvae to immunize young lambs. American Journal of Veterinary Research 27, 1641-3.
26. VASSALLI, P. (1992). The pathophysiology of tumor necrosis factors. Annual Review of Immunology 10, 411-52.
27. WALSH, J.H. (1988). Peptides as regulators of gastric acid secretion. Annual Review of Physiology 50, 41-63.
28. WEIGERT, N., SCHAFFER, K., SCHUSDZIARRA, V., CLASSEN, M. & SCHEPP, W. (1996). Gastrin secretion from primary cultures of rabbit antral G cells: stimulation by inflammatory cytokines. Gastroenterology 110, 147-54.
29. WITZEL, L., HALTER, F., OLAH, A. & HÄCKI, W. (1977). Effects of prolonged metiamide medication on the fundic mucosa. A secretory and histomorphometric study in the rat. Gastroenterology 73, 797-803.