Docking studies and effects of syn-anti isomery of oximes derived from pyridine imidazol bicycled systems as potential human acetylcholinesterase reactivators

Journal of Applied Biomedicine

Volumn 9, Issue 3, 2011, Pages 163-171

  Guimarães, Ana Paula ^a,b   França, Tanos Celmar Costa ^a   Ramalho, Teodorico Castro ^b   Rennó, Magdalena Nascimento ^c   da Cunha, Elaine Fontes Ferreira ^b   Matos, Karina Silvia ^b   Mancini, Daiana Teixeira ^b   Kuča, Kamil ^d,e  

^a MILITARY INSTITUTE OF ENGINEERING   (Brazil)

^b FEDERAL UNIVERSITY OF LAVRAS   (Brazil)

^c FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^d UNIVERSITY OF DEFENCE   (Czech Republic)

^e UNIVERSITY HOSPITAL HRADEC KRALOVE   (Czech Republic)

Author keywords

Acetylcholinesterase; Docking studies; Neurotoxic agents; Oximes; Theoretical calculation

Indexed keywords

2 PRALIDOXIME; 3 PRALIDOXIME; 4 PRALIDOXIME; CHOLINESTERASE REACTIVATOR; IMIDAZOLE DERIVATIVE; OBIDOXIME; OXIME DERIVATIVE; PRALIDOXIME; PYRIDINE DERIVATIVE; TRIMEDOXIME; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG EFFECT; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENZYME ACTIVE SITE; ENZYME INHIBITION; ISOMERISM; MOLECULAR DOCKING;

EID: 79958851238     PISSN: 1214021X     EISSN: 12140287     Source Type: Journal    
DOI: 10.2478/v10136-009-0037-1     Document Type: Article

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