메뉴 건너뛰기




Volumn 43, Issue 7, 2011, Pages 458-463

A novel mechanism for decreasing plasma lipid level from imidazoline I-1 receptor activation in high fat diet-fed mice

Author keywords

cholesterol; efaroxan; imidazoline receptor; rilmenidine; triglyceride

Indexed keywords

CHOLESTEROL; EFAROXAN; FARNESOID X RECEPTOR; HIGH DENSITY LIPOPROTEIN; IMIDAZOLINE I1 RECEPTOR; LOW DENSITY LIPOPROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; RILMENIDINE; TRIACYLGLYCEROL;

EID: 79958771832     PISSN: 00185043     EISSN: 14394286     Source Type: Journal    
DOI: 10.1055/s-0031-1275325     Document Type: Article
Times cited : (12)

References (38)
  • 1
    • 0024160877 scopus 로고
    • Banting lecture 1988. Role of insulin resistance in human disease
    • Reaven GM. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 1988; 37: 1595-1607
    • (1988) Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.M.1
  • 2
    • 55449137033 scopus 로고    scopus 로고
    • Triglycerides and risk for coronary artery disease
    • McBride P. Triglycerides and risk for coronary artery disease. Curr Atheroscler Rep 2008; 10: 386-390
    • (2008) Curr Atheroscler Rep , vol.10 , pp. 386-390
    • McBride, P.1
  • 4
    • 0034200828 scopus 로고    scopus 로고
    • Identification and characterization of I1 imidazoline receptors: Their role in blood pressure regulation
    • Bousquet P. Identification and characterization of I1 imidazoline receptors: their role in blood pressure regulation. Am J Hypertens 2000; 13: 84S-88S
    • (2000) Am J Hypertens , vol.13
    • Bousquet, P.1
  • 5
    • 0030639995 scopus 로고    scopus 로고
    • 1-imidazoline receptor: From binding site to therapeutic target in cardiovascular disease
    • Ernsberger P, Friedman JE, Koletsky RJ. The I1-imidazoline receptor: from binding site to therapeutic target in cardiovascular disease. J Hypertens Suppl 1997; 15: S9-S23 (Pubitemid 27089314)
    • (1997) Journal of Hypertension, Supplement , vol.15 , Issue.1
    • Ernsberger, P.1
  • 7
    • 77951499084 scopus 로고    scopus 로고
    • Activation of imidazoline I2B receptors is linked with AMP kinase pathway to increase glucose uptake in cultured C2C12 cells
    • Lui TN, Tsao CW, Huang SY, Chang CH, Cheng JT. Activation of imidazoline I2B receptors is linked with AMP kinase pathway to increase glucose uptake in cultured C2C12 cells. Neurosci Lett 2010; 474: 144-147
    • (2010) Neurosci Lett , vol.474 , pp. 144-147
    • Lui, T.N.1    Tsao, C.W.2    Huang, S.Y.3    Chang, C.H.4    Cheng, J.T.5
  • 8
    • 0034890832 scopus 로고    scopus 로고
    • Biological significance of agmatine, an endogenous ligand at imidazoline binding sites
    • Raasch W, Schafer U, Chun J, Dominiak P. Biological significance of agmatine, an endogenous ligand at imidazoline binding sites. Br J Pharmacol 2001; 133: 755-780 (Pubitemid 32751786)
    • (2001) British Journal of Pharmacology , vol.133 , Issue.6 , pp. 755-780
    • Raasch, W.1    Schafer, U.2    Chun, J.3    Dominiak, P.4
  • 9
    • 0035851188 scopus 로고    scopus 로고
    • Orphan nuclear receptors as eLiXiRs and FiXeRs of sterol metabolism
    • Lu TT, Repa JJ, Mangelsdorf DJ. Orphan nuclear receptors as eLiXiRs and FiXeRs of sterol metabolism. J Biol Chem 2001; 276: 37735-37738
    • (2001) J Biol Chem , vol.276 , pp. 37735-37738
    • Lu, T.T.1    Repa, J.J.2    Mangelsdorf, D.J.3
  • 10
    • 0036851863 scopus 로고    scopus 로고
    • The liver X receptor gene team: Potential new players in atherosclerosis
    • DOI 10.1038/nm1102-1243
    • Repa JJ, Mangelsdorf DJ. The liver X receptor gene team: potential new players in atherosclerosis. Nat Med 2002; 8: 1243-1248 (Pubitemid 35373555)
    • (2002) Nature Medicine , vol.8 , Issue.11 , pp. 1243-1248
    • Repa, J.J.1    Mangelsdorf, D.J.2
  • 11
    • 26244441014 scopus 로고    scopus 로고
    • The Farnesoid X receptor: A molecular link between bile acid and lipid and glucose metabolism
    • Claudel T, Staels B, Kuipers F. The Farnesoid X receptor: a molecular link between bile acid and lipid and glucose metabolism. Arterioscler Thromb Vasc Biol 2005; 25: 2020-2030
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 2020-2030
    • Claudel, T.1    Staels, B.2    Kuipers, F.3
  • 16
    • 65649122273 scopus 로고    scopus 로고
    • Effects of exercise training on hepatic microsomal triglyceride transfer protein content in rats
    • Chapados NA, Seelaender M, Levy E, Lavoie JM. Effects of exercise training on hepatic microsomal triglyceride transfer protein content in rats. Horm Metab Res 2009; 41: 287-393
    • (2009) Horm Metab Res , vol.41 , pp. 287-393
    • Chapados, N.A.1    Seelaender, M.2    Levy, E.3    Lavoie, J.M.4
  • 17
    • 34547791216 scopus 로고    scopus 로고
    • Hypolipidemic effects and mechanisms of Panax notoginseng on lipid profile in hyperlipidemic rats
    • DOI 10.1016/j.jep.2007.06.022, PII S0378874107003121
    • Ji W, Gong BQ. Hypolipidemic effects and mechanisms of Panax notoginseng on lipid profile in hyperlipidemic rats. J Ethnopharmacol 2007; 113: 318-324 (Pubitemid 47239259)
    • (2007) Journal of Ethnopharmacology , vol.113 , Issue.2 , pp. 318-324
    • Ji, W.1    Gong, B.Q.2
  • 18
    • 0141828972 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors, fatty acid oxidation, steatohepatitis and hepatocarcinogenesis
    • DOI 10.2174/1566524033479537
    • Yu S, Rao S, Reddy JK. Peroxisome proliferator-activated receptors, fatty acid oxidation, steatohepatitis and hepatocarcinogenesis. Curr Mol Med 2003; 3: 561-572 (Pubitemid 37168598)
    • (2003) Current Molecular Medicine , vol.3 , Issue.6 , pp. 561-572
    • Yu, S.1    Rao, S.2    Reddy, J.K.3
  • 19
    • 77957871769 scopus 로고    scopus 로고
    • Transcriptional regulation of human and rat hepatic lipid metabolism by the grapefruit flavonoid naringenin: Role of PPARalpha, PPAR-gamma and LXRalpha
    • Goldwasser J, Cohen PY, Yang E, Balaguer P, Yarmush ML, Nahmias Y. Transcriptional regulation of human and rat hepatic lipid metabolism by the grapefruit flavonoid naringenin: role of PPARalpha, PPAR-gamma and LXRalpha. PLoS One 2010; 5: e12399
    • (2010) PLoS One , vol.5
    • Goldwasser, J.1    Cohen, P.Y.2    Yang, E.3    Balaguer, P.4    Yarmush, M.L.5    Nahmias, Y.6
  • 21
    • 77954385136 scopus 로고    scopus 로고
    • Peroxisome proliferator activated receptor alpha (PPARalpha) and PPAR gamma coactivator (PGC-1alpha) induce carnitine palmitoyltransferase IA (CPT-1A) via independent gene elements
    • Song S, Attia RR, Connaughton S, Niesen MI, Ness GC, Elam MB, Hori RT, Cook GA, Park EA. Peroxisome proliferator activated receptor alpha (PPARalpha) and PPAR gamma coactivator (PGC-1alpha) induce carnitine palmitoyltransferase IA (CPT-1A) via independent gene elements . Mol Cell Endocrinol 2010; 325: 54-63
    • (2010) Mol Cell Endocrinol , vol.325 , pp. 54-63
    • Song, S.1    Attia, R.R.2    Connaughton, S.3    Niesen, M.I.4    Ness, G.C.5    Elam, M.B.6    Hori, R.T.7    Cook, G.A.8    Park, E.A.9
  • 22
    • 77955296892 scopus 로고    scopus 로고
    • Resistance to high-fat diet-induced obesity and insulin resistance in mice with very long-chain acyl-CoA dehydrogenase deficiency
    • Zhang D, Christianson J, Liu ZX, Tian L, Choi CS, Neschen S, Dong J, Wood PA, Shulman GI. Resistance to high-fat diet-induced obesity and insulin resistance in mice with very long-chain acyl-CoA dehydrogenase deficiency. Cell Metab 2010; 11: 402-411
    • (2010) Cell Metab , vol.11 , pp. 402-411
    • Zhang, D.1    Christianson, J.2    Liu, Z.X.3    Tian, L.4    Choi, C.S.5    Neschen, S.6    Dong, J.7    Wood, P.A.8    Shulman, G.I.9
  • 24
    • 0037414757 scopus 로고    scopus 로고
    • Natural structural variants of the nuclear receptor farnesoid X receptor affect transcriptional activation
    • DOI 10.1074/jbc.M209505200
    • Zhang Y, Kast-Woelbern HR, Edwards PA. Natural structural variants of the nuclear receptor farnesoid X receptor affect transcriptional activation. J Biol Chem 2003; 278: 104-110 (Pubitemid 36043550)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.1 , pp. 104-110
    • Zhang, Y.1    Kast-Woelbern, H.R.2    Edwards, P.A.3
  • 25
    • 0034664729 scopus 로고    scopus 로고
    • Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis
    • Sinal CJ, Tohkin M, Miyata M, Ward JM, Lambert G, Gonzalez FJ. Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. Cell 2000; 102: 731-744
    • (2000) Cell , vol.102 , pp. 731-744
    • Sinal, C.J.1    Tohkin, M.2    Miyata, M.3    Ward, J.M.4    Lambert, G.5    Gonzalez, F.J.6
  • 26
    • 0036164154 scopus 로고    scopus 로고
    • BAREing it all: The adoption of LXR and FXR and their roles in lipid homeostasis
    • Edwards PA, Kast HR, Anisfeld AM. BAREing it all: the adoption of LXR and FXR and their roles in lipid homeostasis. J Lipid Res 2002; 43: 2-12 (Pubitemid 34117211)
    • (2002) Journal of Lipid Research , vol.43 , Issue.1 , pp. 2-12
    • Edwards, P.A.1    Kast, H.R.2    Anisfeld, A.M.3
  • 28
    • 0034791544 scopus 로고    scopus 로고
    • Farnesoid X-activated receptor induces apolipoprotein C-II transcription: A molecular mechanism linking plasma triglyceride levels to bile acids
    • DOI 10.1210/me.15.10.1720
    • Kast HR, Nguyen CM, Sinal CJ, Jones SA, Laffitte BA, Reue K, Gonzalez FJ, Willson TM, Edwards PA. Farnesoid X-activated receptor induces apolipoprotein C-II transcription: a molecular mechanism linking plasma triglyceride levels to bile acids. Mol Endocrinol 2001; 15: 1720-1728 (Pubitemid 32939302)
    • (2001) Molecular Endocrinology , vol.15 , Issue.10 , pp. 1720-1728
    • Kast, H.R.1    Nguyen, C.M.2    Sinal, C.J.3    Jones, S.A.4    Laffitte, B.A.5    Reue, K.6    Gonzalez, F.J.7    Willson, T.M.8    Edwards, P.A.9
  • 29
    • 0942279602 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXR
    • DOI 10.1101/gad.1138104
    • Zhang Y, Castellani LW, Sinal CJ, Gonzalez FJ, Edwards PA. Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXR. Genes Dev 2004; 18: 157-169 (Pubitemid 38141784)
    • (2004) Genes and Development , vol.18 , Issue.2 , pp. 157-169
    • Zhang, Y.1    Castellani, L.W.2    Sinal, C.J.3    Gonzalez, F.J.4    Edwards, P.A.5
  • 30
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • DOI 10.1172/JCI200215593
    • Horton JD, Goldstein JL, Brown MS. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest 2002; 109: 1125-1131 (Pubitemid 34496588)
    • (2002) Journal of Clinical Investigation , vol.109 , Issue.9 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 31
    • 0025248437 scopus 로고
    • Lipoprotein ApoC-II activation of lipoprotein lipase. Modulation by apolipoprotein A-IV
    • Goldberg IJ, Scheraldi CA, Yacoub LK, Saxena U, Bisgaier CL. Lipoprotein ApoC-II activation of lipoprotein lipase. Modulation by apolipoprotein A-IV. J Biol Chem 1990; 265: 4266-4272
    • (1990) J Biol Chem , vol.265 , pp. 4266-4272
    • Goldberg, I.J.1    Scheraldi, C.A.2    Yacoub, L.K.3    Saxena, U.4    Bisgaier, C.L.5
  • 32
    • 0028817459 scopus 로고
    • Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase. A potential mechanism for the hypolipidemic action of fibrates
    • Staels B, Vu-Dac N, Kosykh VA, Saladin R, Fruchart JC, Dallongeville J, Auwerx J. Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase. A potential mechanism for the hypolipidemic action of fibrates. J Clin Invest 1995; 95: 705-712
    • (1995) J Clin Invest , vol.95 , pp. 705-712
    • Staels, B.1    Vu-Dac, N.2    Kosykh, V.A.3    Saladin, R.4    Fruchart, J.C.5    Dallongeville, J.6    Auwerx, J.7
  • 34
    • 34548819619 scopus 로고    scopus 로고
    • Versatility in ligand recognition by LDL receptor family proteins: Advances and frontiers
    • DOI 10.1016/j.sbi.2007.08.017, PII S0959440X07001248
    • Blacklow SC. Versatility in ligand recognition by LDL receptor family proteins: advances and frontiers. Curr Opin Struct Biol 2007; 17: 419-426 (Pubitemid 47451775)
    • (2007) Current Opinion in Structural Biology , vol.17 , Issue.4 , pp. 419-426
    • Blacklow, S.C.1
  • 35
    • 0003042048 scopus 로고
    • Mevinolin, an inhibitor of cholesterol synthesis, induces mRNA for low density lipoprotein receptor in livers of hamsters and rabbits
    • Ma PT, Gil G, Südhof TC, Bilheimer DW, Goldstein JL, Brown MS. Mevinolin, an inhibitor of cholesterol synthesis, induces mRNA for low density lipoprotein receptor in livers of hamsters and rabbits. Proc Natl Acad Sci U S A 1986; 83: 8370-8374
    • (1986) Proc Natl Acad Sci U S A , vol.83 , pp. 8370-8374
    • Ma, P.T.1    Gil, G.2    Südhof, T.C.3    Bilheimer, D.W.4    Goldstein, J.L.5    Brown, M.S.6
  • 36
    • 0000716338 scopus 로고
    • Mevinolin and colestipol stimulate receptor-mediated clearance of low density lipoprotein from plasma in familial hypercholesterolemia heterozygotes
    • Bilheimer DW, Grundy SM, Brown MS, Goldstein JL. Mevinolin and colestipol stimulate receptor-mediated clearance of low density lipoprotein from plasma in familial hypercholesterolemia heterozygotes. Proc Natl Acad Sci USA 1983; 80: 4124-4128
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 4124-4128
    • Bilheimer, D.W.1    Grundy, S.M.2    Brown, M.S.3    Goldstein, J.L.4
  • 37
    • 0032589139 scopus 로고    scopus 로고
    • Homologous regulation of the alpha2C-adrenoceptor subtype in human hepatocarcinoma, HepG2
    • DOI 10.1038/sj.bjp.0702269
    • Cayla C, Schaak S, Roquelaine C, Gales C, Quinchon F, Paris H. Homologous regulation of the alpha2C-adrenoceptor subtype in human hepatocarcinoma, HepG2. Br J Pharmacol 1999; 126: 69-78 (Pubitemid 29041745)
    • (1999) British Journal of Pharmacology , vol.126 , Issue.1 , pp. 69-78
    • Cayla, C.1    Schaak, S.2    Roquelaine, C.3    Gales, C.4    Quinchon, F.5    Paris, H.6
  • 38
    • 37349106003 scopus 로고    scopus 로고
    • Human cholesterol metabolism and therapeutic molecules
    • DOI 10.1113/expphysiol.2007.035147
    • Charlton-Menys V, Durrington PN. Human cholesterol metabolism and therapeutic molecules. Exp Physiol 2008; 93: 27-42 (Pubitemid 350293976)
    • (2008) Experimental Physiology , vol.93 , Issue.1 , pp. 27-42
    • Charlton-Menys, V.1    Durrington, P.N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.