-
1
-
-
0017810263
-
Do mitochondria produce oxygen radicals in vivo?
-
Nohl, H. and Hegner, D. (1978) Do mitochondria produce oxygen radicals in vivo? Eur. J. Biochem. 82, 563-567.
-
(1978)
Eur. J. Biochem.
, vol.82
, pp. 563-567
-
-
Nohl, H.1
Hegner, D.2
-
2
-
-
0033525773
-
Mitochondrial diseases in man and mouse
-
Wallace, D. C. (1999) Mitochondrial diseases in man and mouse. Science 283, 1482-1488.
-
(1999)
Science
, vol.283
, pp. 1482-1488
-
-
Wallace, D.C.1
-
3
-
-
0034700807
-
Mitochondrial respiratory chain disorders: I. mitochondrial DNA defects
-
Leonard, J. V. and Schapira, A. H. (2000) Mitochondrial respiratory chain disorders: I. mitochondrial DNA defects. Lancet 355, 299-304.
-
(2000)
Lancet
, vol.355
, pp. 299-304
-
-
Leonard, J.V.1
Schapira, A.H.2
-
5
-
-
0142150051
-
Mitochondrial formation of reactive oxygen species
-
Turrens, J. F. (2003) Mitochondrial formation of reactive oxygen species. J. Physiol. 552, 335-344.
-
(2003)
J. Physiol.
, vol.552
, pp. 335-344
-
-
Turrens, J.F.1
-
6
-
-
0018776894
-
Hydroperoxide metabolism in mammalian organs
-
Chance, B., Sies, H. and Boveris, A. (1979) Hydroperoxide metabolism in mammalian organs. Physiol. Rev. 59, 527-605.
-
(1979)
Physiol. Rev.
, vol.59
, pp. 527-605
-
-
Chance, B.1
Sies, H.2
Boveris, A.3
-
7
-
-
4444297565
-
Mitochondria: are they the seat of senescence?
-
Fridovich, I. (2004) Mitochondria: are they the seat of senescence? Aging Cell 3, 13-16.
-
(2004)
Aging Cell
, vol.3
, pp. 13-16
-
-
Fridovich, I.1
-
8
-
-
0030969868
-
Superoxide production by the mitochondrial respiratory chain
-
Turrens, J. F. (1997) Superoxide production by the mitochondrial respiratory chain. Biosci. Rep. 17, 3-8.
-
(1997)
Biosci. Rep.
, vol.17
, pp. 3-8
-
-
Turrens, J.F.1
-
9
-
-
0032504657
-
Role of mitochondria in oxidative stress and ageing
-
Lenaz, G. (1998) Role of mitochondria in oxidative stress and ageing. Biochim. Biophys. Acta. Bioenerg. 1366, 53-67.
-
(1998)
Biochim. Biophys. Acta. Bioenerg.
, vol.1366
, pp. 53-67
-
-
Lenaz, G.1
-
10
-
-
0034626735
-
Oxidants, oxidative stress and the biology of ageing
-
Finkel, T. and Holbrook, N. J. (2000) Oxidants, oxidative stress and the biology of ageing. Nature 408, 239-247.
-
(2000)
Nature
, vol.408
, pp. 239-247
-
-
Finkel, T.1
Holbrook, N.J.2
-
11
-
-
0034306267
-
Mitochondria, oxygen free radicals, disease and ageing
-
Raha, S. and Robinson, B. H. (2000) Mitochondria, oxygen free radicals, disease and ageing. Trends Biochem. Sci. 25, 502-508.
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 502-508
-
-
Raha, S.1
Robinson, B.H.2
-
12
-
-
0142195820
-
Superoxide anion generation by the cytochrome bc1 complex
-
Sun, J. and Trumpower, B. L. (2003) Superoxide anion generation by the cytochrome bc1 complex. Arch. Biochem. Biophys. 419, 198-206.
-
(2003)
Arch. Biochem. Biophys.
, vol.419
, pp. 198-206
-
-
Sun, J.1
Trumpower, B.L.2
-
13
-
-
0037160091
-
Topology of superoxide production from different sites in the mitochondrial electron transport chain
-
St-Pierre, J., Buckingham, J. A., Roebuck, S. J. and Brand, M. D. (2002) Topology of superoxide production from different sites in the mitochondrial lectron transport chain. J. Biol. Chem. 277, 44784-44790.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 44784-44790
-
-
St-Pierre, J.1
Buckingham, J.A.2
Roebuck, S.J.3
Brand, M.D.4
-
14
-
-
33748957197
-
Mitochondrial complex I: structural and functional aspects
-
Lenaz, G., Fato, R., Genova, M. L., Bergamini, C., Bianchi, C. and Biondi, A. (2006) Mitochondrial complex I: structural and functional aspects. Biochim. iophys. Acta. 1757, 1406-1420.
-
(2006)
Biochim. Biophys. Acta.
, vol.1757
, pp. 1406-1420
-
-
Lenaz, G.1
Fato, R.2
Genova, M.L.3
Bergamini, C.4
Bianchi, C.5
Biondi, A.6
-
15
-
-
0035834789
-
A defect in the cytochrome b large subunit in complex II causes both superoxide anion overproduction and abnormal energy metabolism in Caenorhabditis elegans
-
Senoo-Matsuda, N., Yasuda, K., Tsuda, M., Ohkubo, T., Yoshimura, S., Nakazawa, H., Hartman, P. S. and Ishii, N. (2001) A defect in the cytochrome b large subunit in complex II causes both superoxide anion overproduction and abnormal energy metabolism in Caenorhabditis elegans. J. Biol. Chem. 276, 41553-1558.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 41553-41558
-
-
Senoo-Matsuda, N.1
Yasuda, K.2
Tsuda, M.3
Ohkubo, T.4
Yoshimura, S.5
Nakazawa, H.6
Hartman, P.S.7
Ishii, N.8
-
16
-
-
11244279161
-
A mutation in the SDHC gene of complex II increases oxidative stress, resulting in apoptosis and tumorigenesis
-
Ishii, T., Yasuda, K., Akatsuka, A., Hino, O., Hartman, P. S. and Ishii, N. (2005) A mutation in the SDHC gene of complex II increases oxidative stress, resulting in apoptosis and tumorigenesis. Cancer Res. 65, 203-209.
-
(2005)
Cancer Res
, vol.65
, pp. 203-209
-
-
Ishii, T.1
Yasuda, K.2
Akatsuka, A.3
Hino, O.4
Hartman, P.S.5
Ishii, N.6
-
17
-
-
76049086567
-
Contribution of the FAD and quinone binding sites to the production of reactive oxygen species from Ascaris suum mitochondrial complex II
-
Paranagama, M. P., Sakamoto, K., Amino, H., Awano, M., Miyoshi, H. and Kita, K. (2010) Contribution of the FAD and quinone binding sites to the production of reactive oxygen species from Ascaris suum mitochondrial complex II. Mitochondrion 10, 158-165.
-
(2010)
Mitochondrion
, vol.10
, pp. 158-165
-
-
Paranagama, M.P.1
Sakamoto, K.2
Amino, H.3
Awano, M.4
Miyoshi, H.5
Kita, K.6
-
18
-
-
28544446058
-
Mitochondrial tumour suppressors: a genetic and biochemical update
-
Gottlieb, E. and Tomlinson, I. P. (2005) Mitochondrial tumour suppressors: a genetic and biochemical update. Nat. Rev. Cancer 5, 857-866.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 857-866
-
-
Gottlieb, E.1
Tomlinson, I.P.2
-
19
-
-
34948890043
-
Mitochondrial uncoupling proteinswhat is their physiological role? Free Radic
-
Echtay, K. S. (2007) Mitochondrial uncoupling proteinswhat is their physiological role? Free Radic. Biol. Med. 43, 1351-1371.
-
(2007)
Biol. Med.
, vol.43
, pp. 1351-1371
-
-
Echtay, K.S.1
-
20
-
-
0032578458
-
Mitochondrial reactive oxygen species trigger hypoxia-induced transcription
-
Chandel, N. S., Maltepe, E., Goldwasser, E., Mathieu, C. E., Simon, M. C. and Schumacker, P. T. (1998) Mitochondrial reactive oxygen species trigger hypoxia-induced transcription. Proc. Natl. Acad. Sci. U.S.A. 95, 11715-11720.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 11715-11720
-
-
Chandel, N.S.1
Maltepe, E.2
Goldwasser, E.3
Mathieu, C.E.4
Simon, M.C.5
Schumacker, P.T.6
-
21
-
-
24144493814
-
Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing
-
Guzy, R. D., Hoyos, B., Robin, E., Chen, H., Liu, L., Mansfield, K. D., Simon, M. C., Hammerling, U. and Schumacker, P. T. (2005) Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing. Cell Metab. 1, 401-408.
-
(2005)
Cell Metab
, vol.1
, pp. 401-408
-
-
Guzy, R.D.1
Hoyos, B.2
Robin, E.3
Chen, H.4
Liu, L.5
Mansfield, K.D.6
Simon, M.C.7
Hammerling, U.8
Schumacker, P.T.9
-
22
-
-
64449087671
-
Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio
-
Emerling, B. M., Weinberg, F., Snyder, C., Burgess, Z., Mutlu, G. M., Viollet, B., Budinger, G. R. and Chandel, N. S. (2009) Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio. Free Radic. Biol. Med. 46, 1386-1391.
-
(2009)
Free Radic. Biol. Med.
, vol.46
, pp. 1386-1391
-
-
Emerling, B.M.1
Weinberg, F.2
Snyder, C.3
Burgess, Z.4
Mutlu, G.M.5
Viollet, B.6
Budinger, G.R.7
Chandel, N.S.8
-
23
-
-
0023235226
-
Reduced oxygen species, mutation, induction and cancer initiation
-
Vuillaume, M. (1987) Reduced oxygen species, mutation, induction and cancer initiation. Mutat. Res. 186, 43-72.
-
(1987)
Mutat. Res.
, vol.186
, pp. 43-72
-
-
Vuillaume, M.1
-
24
-
-
0031042807
-
Oxidative DNA damage in human cells: the influence of antioxidants and DNA repair
-
Collins, A. R., Duthie, S. J., Fillion, L., Gedik, C. M., Vaughan, N. and Wood, S. G. (1997) Oxidative DNA damage in human cells: the influence of ntioxidants and DNA repair. Biochem. Soc. Trans. 25, 326-331.
-
(1997)
Biochem. Soc. Trans.
, vol.25
, pp. 326-331
-
-
Collins, A.R.1
Duthie, S.J.2
Fillion, L.3
Gedik, C.M.4
Vaughan, N.5
Wood, S.G.6
-
25
-
-
0037411282
-
4-Hydroxy-2-nonenal: a product and mediator of oxidative stress
-
Uchida K. (2003) 4-Hydroxy-2-nonenal: a product and mediator of oxidative stress. Prog. Lipid Res. 42, 318-343.
-
(2003)
Prog. Lipid Res.
, vol.42
, pp. 318-343
-
-
Uchida, K.1
-
26
-
-
0023229496
-
Oxygen radicals and diseases
-
Cross, C. E., Halliwell, B., Borish, E. T., Pryor, W. A., Ames, B. N., Saul, R. L., McCord, J. M. and Harman, D. (1987) Oxygen radicals and diseases. nn. Intrern. Med. 107, 526-545.
-
(1987)
Ann. Intrern. Med.
, vol.107
, pp. 526-545
-
-
Cross, C.E.1
Halliwell, B.2
Borish, E.T.3
Pryor, W.A.4
Ames, B.N.5
Saul, R.L.6
McCord, J.M.7
Harman, D.8
-
27
-
-
27544484846
-
Are mitochondria critical in the pathogenesis of Alzheimer's disease?
-
Reddy, P. H. and Beal, M. F. (2005) Are mitochondria critical in the pathogenesis of Alzheimer's disease? Brain Res. Rev. 49, 618-632.
-
(2005)
Brain Res. Rev
, vol.49
, pp. 618-632
-
-
Reddy, P.H.1
Beal, M.F.2
-
28
-
-
33645879820
-
Oxidative damage and age-related functional declines
-
Martin, I. and Grotewiel, M. S. (2006) Oxidative damage and age-related functional declines. Mech. Ageing Dev. 127, 411-423.
-
(2006)
Mech. Ageing Dev.
, vol.127
, pp. 411-423
-
-
Martin, I.1
Grotewiel, M.S.2
-
29
-
-
32444433202
-
Free radicals, metals and antioxidants in oxidative stress-induced cancer
-
Valko, M., Rhodes, C. J., Moncol, J., Izakovic, M. and Mazur, M. (2006) Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem. iol. Interact. 160, 1-40.
-
(2006)
Chem. Biol. Interact.
, vol.160
, pp. 1-40
-
-
Valko, M.1
Rhodes, C.J.2
Moncol, J.3
Izakovic, M.4
Mazur, M.5
-
30
-
-
33749986298
-
Free radicals and antioxidants in normal physiological functions and human disease
-
Valko, M., Leibfritz, D., Moncol, J., Cronin, M. T., Mazur, M. and Telser, J. (2007) Free radicals and antioxidants in normal physiological functions and uman disease. Int. J. Biochem. Cell Biol. 39, 44-84.
-
(2007)
Int. J. Biochem. Cell Biol.
, vol.39
, pp. 44-84
-
-
Valko, M.1
Leibfritz, D.2
Moncol, J.3
Cronin, M.T.4
Mazur, M.5
Telser, J.6
-
31
-
-
0017295767
-
Characterization of the mitochondria of the free-living nematode Caenorhabditis elegans
-
Murfitt, R. R., Vogel, K. and Sanadi, D. R. (1976) Characterization of the mitochondria of the free-living nematode, Caenorhabditis elegans. Comp. Biochem. Physiol. B. 53, 423-430.
-
(1976)
Comp. Biochem. Physiol. B.
, vol.53
, pp. 423-430
-
-
Murfitt, R.R.1
Vogel, K.2
Sanadi, D.R.3
-
32
-
-
0026573893
-
The mitochondrial genomes of two nematodes
-
Okimoto, R., Macfarlane, J. L., Clary, D. O. and Wolstenholme, D. R. (1992) The mitochondrial genomes of two nematodes, Caenorhabditis elegans and scaris suum. Genetics 130, 471-498.
-
(1992)
Caenorhabditis elegans and Ascaris suum. Genetics
, vol.130
, pp. 471-498
-
-
Okimoto, R.1
Macfarlane, J.L.2
Clary, D.O.3
Wolstenholme, D.R.4
-
33
-
-
0032514466
-
A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes
-
Ishii, N., Fujii, M., Hartman, P. S., Tsuda, M., Yasuda, K., Senoo-Matsuda, N., Yanase, S., Ayusawa, D. and Suzuki, K. (1998) A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes. Nature 394, 694-697.
-
(1998)
Nature
, vol.394
, pp. 694-697
-
-
Ishii, N.1
Fujii, M.2
Hartman, P.S.3
Tsuda, M.4
Yasuda, K.5
Senoo-Matsuda, N.6
Yanase, S.7
Ayusawa, D.8
Suzuki, K.9
-
34
-
-
34748922899
-
A mev-1-like dominant-negative SdhC increases oxidative stress and reduces lifespan in Drosophila
-
Tsuda, M., Sugiura, T., Ishii, T., Ishii, N. and Aigaki, T.,(2007) A mev-1-like dominant-negative SdhC increases oxidative stress and reduces lifespan in rosophila. Biochem. Biophys. Res. Commun. 363, 342-346.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.363
, pp. 342-346
-
-
Tsuda, M.1
Sugiura, T.2
Ishii, T.3
Ishii, N.4
Aigaki, T.5
-
35
-
-
0025185977
-
A methyl viologen-sensitive mutant of the nematode Caenorhabditis elegans
-
Ishii, N., Takahashi, K., Tomita, S., Keino, T., Honda, S., Yoshino, K. and Suzuki, K. (1990) A methyl viologen-sensitive mutant of the nematode aenorhabditis elegans. Mutat. Res. 237, 165-171.
-
(1990)
Mutat. Res.
, vol.237
, pp. 165-171
-
-
Ishii, N.1
Takahashi, K.2
Tomita, S.3
Keino, T.4
Honda, S.5
Yoshino, K.6
Suzuki, K.7
-
36
-
-
0027467912
-
Oxygen-dependent perturbation of life span and aging rate in the nematode
-
Honda, S., Ishii, N., Suzuki, K. and Matsuo, M. (1993) Oxygen-dependent perturbation of life span and aging rate in the nematode. J. Gerontl. Ser. A Biol. ci. 48, B57-B61.
-
(1993)
J. Gerontl. Ser. A Biol. Sci.
, vol.48
-
-
Honda, S.1
Ishii, N.2
Suzuki, K.3
Matsuo, M.4
-
37
-
-
85047289687
-
Rate and magnitude of age pigment accumulation in the human myocardium
-
Strehler, B. L., Mark, D. D., Mildvan, A. S. and Gee, M. V. (1959) Rate and magnitude of age pigment accumulation in the human myocardium. J. Gerontl. 4, 257-264.
-
(1959)
J. Gerontl.
, vol.14
, pp. 257-264
-
-
Strehler, B.L.1
Mark, D.D.2
Mildvan, A.S.3
Gee, M.V.4
-
38
-
-
0016143131
-
Accumulation of lipofuscin in the myocardium of senile guinia pigs; dissolution and removal of lipofuscin following dimethylaminoethyl p-chloroohenoxyacetate administration. An electron microscopy study
-
Spoerri, P. E., Glass, P. and El Ghazzawi, E. (1974) Accumulation of lipofuscin in the myocardium of senile guinia pigs; dissolution and removal of lipofuscin following dimethylaminoethyl p-chloroohenoxyacetate administration. An electron microscopy study. Mech. Ageing Dev. 3, 311-321.
-
(1974)
Mech. Ageing Dev.
, vol.3
, pp. 311-321
-
-
Spoerri, P.E.1
Glass, P.2
El Ghazzawi, E.3
-
39
-
-
0025911829
-
Metal-catalyzed oxidation of proteins
-
Stadman, E. R. and Oliver, C. N. (1991) Metal-catalyzed oxidation of proteins. J. Biol. Chem. 266, 2005-2008.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 2005-2008
-
-
Stadman, E.R.1
Oliver, C.N.2
-
40
-
-
0026795635
-
Protein oxidation and aging
-
Stadman, E. R. (1992) Protein oxidation and aging. Science 257, 1220-1224.
-
(1992)
Science
, vol.257
, pp. 1220-1224
-
-
Stadman, E.R.1
-
41
-
-
0028228780
-
Rapid accumulation of fluorescent material with aging in an oxygen-sensitive mutant mev-1 of Caenorhabditis elegans
-
Hosokawa, H., Ishii, N., Ishida, H., Ichimori, K., Nakazawa, H. and Suzuki, K. (1994) Rapid accumulation of fluorescent material with aging in an oxygen-sensitive mutant mev-1 of Caenorhabditis elegans. Mech. Ageing Dev. 74, 161-170.
-
(1994)
Mech. Ageing Dev.
, vol.74
, pp. 161-170
-
-
Hosokawa, H.1
Ishii, N.2
Ishida, H.3
Ichimori, K.4
Nakazawa, H.5
Suzuki, K.6
-
42
-
-
0031904566
-
Effects of oxygen on protein carbonyl and aging in Caenorhabditis elegans mutants with long (age-1) and short (mev-1) life spans
-
Adachi, H., Fujiwara, Y. and Ishii, N. (1998) Effects of oxygen on protein carbonyl and aging in Caenorhabditis elegans mutants with long (age-1) and short (mev-1) life spans. J. Gerontol. Ser. A Biol. Sci. Med. Sci. 53, B240-B244.
-
(1998)
J. Gerontol. Ser. A Biol. Sci. Med. Sci.
, vol.53
-
-
Adachi, H.1
Fujiwara, Y.2
Ishii, N.3
-
43
-
-
0037820623
-
A complex II defect affects mitochondrial structure, leading to ced-3- and ced-4-dependent apoptosis and aging
-
Senoo-Matsuda, N., Hartman, P. S., Akatsuka, A., Yoshimura, S. and Ishii, N. (2003) A complex II defect affects mitochondrial structure, leading to ced-3- and ced-4-dependent apoptosis and aging. J. Biol. Chem. 278, 22031-22036.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 22031-22036
-
-
Senoo-Matsuda, N.1
Hartman, P.S.2
Akatsuka, A.3
Yoshimura, S.4
Ishii, N.5
-
44
-
-
0034994933
-
Mitochondrial mutations differentially affect aging, mutability and anesthetic sensitivity in Caenorhabditis elegans
-
Hartman, P. S, Ishii, N., Kayser, E. B., Morgan, P. G. and Sedensky, M. M. (2001) Mitochondrial mutations differentially affect aging, mutability and anesthetic sensitivity in Caenorhabditis elegans. Mech. Ageing Dev. 122, 1187-1201.
-
(2001)
Mech. Ageing Dev.
, vol.122
, pp. 1187-1201
-
-
Hartman, P.S.1
Ishii, N.2
Kayser, E.B.3
Morgan, P.G.4
Sedensky, M.M.5
-
45
-
-
0348150715
-
Architecture of succinate dehydrogenase and reactive oxygen species generation
-
Yankovskaya, V., Horsefield, R., Törnroth, S., Luna-Chavez, C., Miyoshi, H., Léger, C., Byrne, B., Cecchini, G. and Iwata, S. (2003) Architecture of succinate dehydrogenase and reactive oxygen species generation. Science 299, 700-704.
-
(2003)
Science
, vol.299
, pp. 700-704
-
-
Yankovskaya, V.1
Horsefield, R.2
Törnroth, S.3
Luna-Chavez, C.4
Miyoshi, H.5
Léger, C.6
Byrne, B.7
Cecchini, G.8
Iwata, S.9
-
46
-
-
0043269302
-
Function and structure of complex II of the respiratory chain
-
Cecchini, G. (2003) Function and structure of complex II of the respiratory chain. Annu. Rev. Biochem. 72, 77-109.
-
(2003)
Annu. Rev. Biochem.
, vol.72
, pp. 77-109
-
-
Cecchini, G.1
-
47
-
-
21244503033
-
Crystal structure of mitochondrial respiratory membrane protein complex II
-
Sun, F., Huo, X., Zhai, Y. A., Wang, A., Xu, J., Su, D., Bartlam, M. and Rao, Z. (2005) Crystal structure of mitochondrial respiratory membrane protein omplex II. Cell 121, 1043-1057.
-
(2005)
Cell
, vol.121
, pp. 1043-1057
-
-
Sun, F.1
Huo, X.2
Zhai, Y.A.3
Wang, A.4
Xu, J.5
Su, D.6
Bartlam, M.7
Rao, Z.8
-
48
-
-
0029159804
-
Mutation of a nuclear succinate dehydrogenase gene results in mitochondrial respiratory chain deficiency
-
Bourgeron, T., Rustin, P., Chretien, D., Birch-Machin, M., Bourgeois, M., Viegas-Péquignot, E., Munnich, A. and Rötig, A. (1995) Mutation of a nuclear succinate dehydrogenase gene results in mitochondrial respiratory chain deficiency. Nat. Genet. 11, 144-149.
-
(1995)
Nat. Genet.
, vol.11
, pp. 144-149
-
-
Bourgeron, T.1
Rustin, P.2
Chretien, D.3
Birch-Machin, M.4
Bourgeois, M.5
Viegas-Péquignot, E.6
Munnich, A.7
Rötig, A.8
-
49
-
-
0033983147
-
Progress in understanding structure-function relationships in respiratory chain complex II
-
Ackrell, B. A. (2000) Progress in understanding structure-function relationships in respiratory chain complex II. FEBS Lett. 466, 1-5.
-
(2000)
FEBS Lett
, vol.466
, pp. 1-5
-
-
Ackrell, B.A.1
-
50
-
-
0036805853
-
Cytopathies involving mitochondrial complex II
-
Ackrell, B. A. (2002) Cytopathies involving mitochondrial complex II. Mol. Aspects. Med. 23, 369-384.
-
(2002)
Mol. Aspects. Med.
, vol.23
, pp. 369-384
-
-
Ackrell, B.A.1
-
51
-
-
0034602950
-
Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma
-
Baysal, B. E., Ferrell, R. E., Willett-Brozick, J. E., Lawrence, E. C., Myssiorek, D., Bosch, A., van der Mey, A., Taschner, P. E., Rubinstein, W. S., Myers, E. N., Richard, C. W. 3rd, Cornelisse, C. J., Devilee, P. and Devlin, B. (2000) Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma. cience 287, 848-851.
-
(2000)
Science
, vol.287
, pp. 848-851
-
-
Baysal, B.E.1
Ferrell, R.E.2
Willett-Brozick, J.E.3
Lawrence, E.C.4
Myssiorek, D.5
Bosch, A.6
van der Mey, A.7
Taschner, P.E.8
Rubinstein, W.S.9
Myers, E.N.10
Richard 3rd, C.W.11
Cornelisse, C.J.12
Devilee, P.13
Devlin, B.14
-
52
-
-
0033767445
-
Mutations in SDHC cause autosomal dominant paraganglioma, type 3
-
Niemann, S. and Müller U. (2000) Mutations in SDHC cause autosomal dominant paraganglioma, type 3. Nat. Genet. 26, 268-270.
-
(2000)
Nat. Genet.
, vol.26
, pp. 268-270
-
-
Niemann, S.1
Müller, U.2
-
53
-
-
0034964421
-
Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma
-
Astuti, D., Latif, F., Dallol, A., Dahia, P. L., Douglas, F., George, E., Sköldberg, F., Husebye, E. S., Eng, C. and Maher, E. R. (2001) Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma. Am. J. Hum. Genet. 69, 49-54.
-
(2001)
Am. J. Hum. Genet.
, vol.69
, pp. 49-54
-
-
Astuti, D.1
Latif, F.2
Dallol, A.3
Dahia, P.L.4
Douglas, F.5
George, E.6
Sköldberg, F.7
Husebye, E.S.8
Eng, C.9
Maher, E.R.10
-
54
-
-
0035213138
-
The R22X mutation of the SDHD gene in hereditary paraganglioma abolishes the enzymatic activity of complex II in the mitochondrial respiratory chain and activates the hypoxia pathway
-
Gimenez-Roqueplo, A. P., Favier, J., Rustin, P., Mourad, J. J., Plouin, P. F., Corvol, P., Rötig, A. and Jeunemaitre, X. (2001) The R22X mutation of the SDHD gene in hereditary paraganglioma abolishes the enzymatic activity of complex II in the mitochondrial respiratory chain and activates the hypoxia pathway. Am. . Hum. Genet. 69, 1186-1197.
-
(2001)
Am. J. Hum. Genet
, vol.69
, pp. 1186-1197
-
-
Gimenez-Roqueplo, A.P.1
Favier, J.2
Rustin, P.3
Mourad, J.J.4
Plouin, P.F.5
Corvol, P.6
Rötig, A.7
Jeunemaitre, X.8
-
55
-
-
0036774422
-
Functional consequences of a SDHB gene mutation in an apparently sporadic pheochromocytoma
-
Gimenez-Roqueplo, A. P., Favier, J., Rustin, P., Rieubland, C., Kerlan, V., Plouin, P. F., Rötig, A. and Jeunemaitre, X. (2002) Functional consequences of a SDHB gene mutation in an apparently sporadic pheochromocytoma. J. Clin. Endocrinol. Metab. 87, 4771-4774.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 4771-4774
-
-
Gimenez-Roqueplo, A.P.1
Favier, J.2
Rustin, P.3
Rieubland, C.4
Kerlan, V.5
Plouin, P.F.6
Rötig, A.7
Jeunemaitre, X.8
-
56
-
-
19944433653
-
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase
-
Selak, M. A., Armour, S. M., MacKenzie, E. D., Boulahbel, H., Watson, D. G., Mansfield, K. D., Pan, Y., Simon, M. C., Thompson, C. B. and Gottlieb, E. (2005) Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase. Cancer Cell 7, 77-85.
-
(2005)
Cancer Cell
, vol.7
, pp. 77-85
-
-
Selak, M.A.1
Armour, S.M.2
MacKenzie, E.D.3
Boulahbel, H.4
Watson, D.G.5
Mansfield, K.D.6
Pan, Y.7
Simon, M.C.8
Thompson, C.B.9
Gottlieb, E.10
-
57
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza, G. L. (2003) Targeting HIF-1 for cancer therapy. Nat. Rev. Cancer 3, 721-732.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
58
-
-
0035834582
-
Correlation of functional and ultrastructural abnormalities of mitochondria in mouse heart carrying a pathogenic mutant mtDNA with a 4696-bp deletion
-
Nakada, K., Inoue, K., Chen, C. S., Nonaka, I., Goto, Y., Ogura, A. and Hayashi, J. I. (2001) Correlation of functional and ultrastructural abnormalities of mitochondria in mouse heart carrying a pathogenic mutant mtDNA with a 4696-bp deletion. Biochem. Biophys. Res. Commun. 288, 901-907.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.288
, pp. 901-907
-
-
Nakada, K.1
Inoue, K.2
Chen, C.S.3
Nonaka, I.4
Goto, Y.5
Ogura, A.6
Hayashi, J.I.7
-
59
-
-
0036890323
-
Complex II inactivation is lethal in the nematode Caenorhabditis elegans
-
Ichimiya, H., Huet, R. G., Hartman, P., Amino, H., Kita, K. and Ishii, N. (2002) Complex II inactivation is lethal in the nematode Caenorhabditis elegans. itochondrion 2, 191-198.
-
(2002)
Mitochondrion
, vol.2
, pp. 191-198
-
-
Ichimiya, H.1
Huet, R.G.2
Hartman, P.3
Amino, H.4
Kita, K.5
Ishii, N.6
-
60
-
-
77952312782
-
Cell growth of the mouse SDHC mutant cells was suppressed by apoptosis throughout mitochondrial pathway
-
Miyazawa, M., Ishii, T., Kirinashizawa, M., Yasuda, K., Hino, O., Hartman, P. S. and Ishii, N. (2008) Cell growth of the mouse SDHC mutant cells was suppressed by apoptosis throughout mitochondrial pathway. BioScience Trends 2, 22-30.
-
(2008)
BioScience Trends
, vol.2
, pp. 22-30
-
-
Miyazawa, M.1
Ishii, T.2
Kirinashizawa, M.3
Yasuda, K.4
Hino, O.5
Hartman, P.S.6
Ishii, N.7
-
61
-
-
78650018619
-
Mitochondrial reactive oxygen species generation by the SDHC V69E mutation causes low birth weight and neonatal growth retardation
-
Ishii, T., Miyazawa, M., Onodera, A., Yasuda, K., Kawabe, N., Kirinashizawa, M., Yoshimura, S., Maruyama, N., Hartman, P. S. and Ishii, N. (2011) Mitochondrial reactive oxygen species generation by the SDHC V69E mutation causes low birth weight and neonatal growth retardation. Mitochondrion 11, 155-65.
-
(2011)
Mitochondrion
, vol.11
, pp. 155-165
-
-
Ishii, T.1
Miyazawa, M.2
Onodera, A.3
Yasuda, K.4
Kawabe, N.5
Kirinashizawa, M.6
Yoshimura, S.7
Maruyama, N.8
Hartman, P.S.9
Ishii, N.10
-
62
-
-
0026720075
-
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
-
Gossen, M. and Bujard, H. (1992) Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. U.S.A. 9, 5547-5551.
-
(1992)
Proc. Natl. Acad. Sci. U. S. A.
, vol.89
, pp. 5547-5551
-
-
Gossen, M.1
Bujard, H.2
-
63
-
-
0029022369
-
Transcriptional activation by tetracyclines in mammalian cells
-
Gossen, M., Freundlieb, S., Bender, G., Muller, G., Hillen, W. and Bujard, H. (1995) Transcriptional activation by tetracyclines in mammalian cells. Science 68, 1766-1769.
-
(1995)
Science
, vol.268
, pp. 1766-1769
-
-
Gossen, M.1
Freundlieb, S.2
Bender, G.3
Muller, G.4
Hillen, W.5
Bujard, H.6
-
64
-
-
0032600013
-
A tetracycline controlled activation/repression system with increased potential for gene transfer into mammalian cells
-
Freundlieb, S., Schirra-Muller, C. and Bujard, H. (1999) A tetracycline controlled activation/repression system with increased potential for gene transfer into ammalian cells. J. Gene Med. 1, 4-12.
-
(1999)
J. Gene Med.
, vol.1
, pp. 4-12
-
-
Freundlieb, S.1
Schirra-Muller, C.2
Bujard, H.3
-
65
-
-
33645088922
-
Tight regulation of transgene expression by tetracycline-dependent activator and repressor in brain
-
Uchida, S., Sakai, S., Furuichi, T., Hosoda, H., Toyota, K., Ishii, T., Kitamoto, A., Sekine, M., Koike, K., Masushige, S., Murphy, G., Silva, A. J. and Kida, S. (2006) Tight regulation of transgene expression by tetracycline-dependent activator and repressor in brain. Genes Brain Behav. 5, 96-106.
-
(2006)
Genes Brain Behav
, vol.5
, pp. 96-106
-
-
Uchida, S.1
Sakai, S.2
Furuichi, T.3
Hosoda, H.4
Toyota, K.5
Ishii, T.6
Kitamoto, A.7
Sekine, M.8
Koike, K.9
Masushige, S.10
Murphy, G.11
Silva, A.J.12
Kida, S.13
-
66
-
-
0018749490
-
Role of superoxide dismutase in cancer: a review
-
Oberley, L. W. and Buettner, G. R. (1979) Role of superoxide dismutase in cancer: a review. Cancer Res. 39, 1141-1149.
-
(1979)
Cancer Res
, vol.39
, pp. 1141-1149
-
-
Oberley, L.W.1
Buettner, G.R.2
-
67
-
-
0019230916
-
Cell differentiation, aging and cancer: the possible roles of superoxide and superoxide dismutases
-
Oberley, L. W., Oberley, T. D. and Buettner, G. R. (1980) Cell differentiation, aging and cancer: the possible roles of superoxide and superoxide dismutases. ed. Hypotheses 6, 249-268.
-
(1980)
Med. Hypotheses
, vol.6
, pp. 249-268
-
-
Oberley, L.W.1
Oberley, T.D.2
Buettner, G.R.3
-
68
-
-
0024270397
-
Role of antioxidant enzymes in cell immortalization and transformation
-
Oberley, L. W. and Oberley, T. D. (1988) Role of antioxidant enzymes in cell immortalization and transformation. Mol. Cell. Biochem. 84, 147-153.
-
(1988)
Mol. Cell. Biochem.
, vol.84
, pp. 147-153
-
-
Oberley, L.W.1
Oberley, T.D.2
-
69
-
-
77955301066
-
The NADH-fumarate reductase system, a novel mitochondrial energy metabolism, is a new target for anticancer therapy in tumor microenvironments
-
Tomitsuka, E., Kita, K. and Esumi H. (2010) The NADH-fumarate reductase system, a novel mitochondrial energy metabolism, is a new target for anticancer therapy in tumor microenvironments. Ann. NY Acad. Sci. 1201, 44-49.
-
(2010)
Ann. NY Acad. Sci
, vol.1201
, pp. 44-49
-
-
Tomitsuka, E.1
Kita, K.2
Esumi, H.3
|