A complex II defect affects mitochondrial structure, leading to ced-3- and ced-4-dependent apoptosis and aging

Journal of Biological Chemistry

Volumn 278, Issue 24, 2003, Pages 22031-22036

  Senoo Matsuda, Nanami ^a,b   Hartman, Philip S ^c   Akatsuka, Akira ^a   Yoshimura, Shinichi ^a   Ishii, Naoaki ^a  

^a TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KYOWA HAKKO KOGYO CO LTD   (Japan)

^c TEXAS CHRISTIAN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; MOLECULAR STRUCTURE; OXIDATION;

MITOCHONDRIA;

ENZYMES;

PROTEIN CYT 1; SUCCINATE DEHYDROGENASE (UBIQUINONE); SUPEROXIDE; UNCLASSIFIED DRUG;

AGING; ANIMAL CELL; APOPTOSIS; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; ELECTRON TRANSPORT; EMBRYO DEVELOPMENT; GENE; GENE MUTATION; HYPEROXIA; LIFESPAN; MEMBRANE POTENTIAL; MEV 1 GENE; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

AGING; ANIMALS; ANOXIA; ANTIBODIES, MONOCLONAL; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BLOTTING, WESTERN; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CALCIUM-BINDING PROTEINS; CASPASES; CYTOCHROMES; CYTOCHROMES B; IMMUNOHISTOCHEMISTRY; MEMBRANE POTENTIALS; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; MODELS, BIOLOGICAL; MUTATION; OXYGEN; PROTO-ONCOGENE PROTEINS; TIME FACTORS;

ANIMALIA; CAENORHABDITIS; CAENORHABDITIS ELEGANS;

EID: 0037820623     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M211377200     Document Type: Article

References (18)

1. Beckman, K. B., and Ames, B. N. (1999) Physiol. Rev. 78, 547-581
2. Finkel, T., and Holbrook, N. J. (2000) Nature 408, 239-247
3. Liu, Q. A., and Hengartner, M. C. (1999) Ann. N. Y. Acad. Sci. 887, 92-104
4. Meier, P., Finch, A., and Evan, C. (2000) Nature 407, 796-801
5. Morgan, J. A., and Hann M. G. (1999) Biochim. Biophys. Acta 1410, 125-145
6. Wallace, D. G. (1999) Science 283, 1482-1488
7. Ishii, N., Michikhiko, F., Hartman, P. S., Tsuda, M., Yasuda, K., Senoo-Matsuda, N., Yanases, S., Ayusawa, D., and Suzuki, K. (1998) Nature 394, 694-697
8. Ishii, N., Takahashi, K., Tornita, S., Keino, T., Honda, S., Yoshino, K., and Suzuki, K. (1990) Mutat. Res. 237, 165-171
9. Honda, S., Ishii, N., Suzuki, K., and Matsuo, M. (1993) J. Gerontol. 48, B57-B61
10. Adachi, H., Fujiwara, Y., and Ishii, N. (1998) J. Gerontol. 53A, B240-B244
11. Hosokawa, H., Ishii, N., Ishida, H., Ichimori, K., Nakazawa, H., and Suzuki, K. (1994) Mech. Ageing Dev. 74, 161-170
12. Senoo-Matsuda, N., Yasuda, K., Tsuda, M., Ohkubo T., Yoshimura, S., Nakazawa, H., Hartman, P. S., and Ishii, N. (2001) J. Biol. Chem. 276, 41553-41558
13. Brenner, S. (1974) Genetics 77, 71-94
14. Mitchell, D. H, Stiles, J. W., Satelli J., and Sanadi, D. R. (1979) J. Gerontol. 35, 28-36
15. Sulston, J. E., Schierenberg, E., White, J. G., and Thomson, N. (1983) Dev. Biol. 100, 64-119
16. Stadhouders, A. M., Jap, P. H. K., Winkler, H.-P., Eppenberger, H. M., and Wallimann, T. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 5089-5093
17. Gartner, A., Milstein, S., Ahmed, S., Hodgkin, J., and Hengartner, M. O. (2000) Mol. Cell 5, 435-443
18. Evan, G., and Littlewood, T. (1998) Science 281, 1317-1322