Melt extrusion can bring new benefits to HIV therapy: The example of Kaletra® tablets

American Journal of Drug Delivery

Volumn 4, Issue 2, 2006, Pages 61-64

  Breitenbach, Jörg ^a  

^a ABBOTT GMBH AND CO KG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; LOPINAVIR PLUS RITONAVIR; POLYMER; PROTEINASE INHIBITOR; VERAPAMIL;

COMPRESSION; DISPERSION; DRUG BIOAVAILABILITY; DRUG FORMULATION; DRUG MANUFACTURE; DRUG SOLUBILITY; FOOD INTAKE; FREEZING; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; IMPLANT; MEDICAL TECHNOLOGY; MELT EXTRUSION; PRIORITY JOURNAL; REVIEW; STENT; SUSPENSION; TABLET;

EID: 33745929028     PISSN: 11759038     EISSN: 11759038     Source Type: Journal    
DOI: 10.2165/00137696-200604020-00001     Document Type: Review

References (8)

1. Breitenbach J, Lewis J. Two concepts, one technology: controlled release and solid dispersions with Meltrex. In: Rathbone MJ, Hadgraft J, Roberts MS, editors. Modified-release drug delivery technology. New York: Marcel Dekker, 2002: 125-33
2. Breitenbach J. Melt extrusion: from process to drug delivery technology. Eur J Pharm Biopharm 2002; 54: 107-17
3. Wood Mackenzie's Productview™. Edinburgh: Wood Mackenzie, 2005 Apr
4. Breitenbach J, Schrof W, Neumann J. Confocal raman-spectrocopy: analytical approach to solid dispersion systems and mapping of drugs. Pharm Res 1999; 16: 1109-13
5. Meltrex [online]. Available from URL: http://www.soliqs.com [Accessed 2006 Apr 5]
6. Cvetkovic RS, Goa KL. Lopinavir/ritonavir: a review of its use in the management of HIV infection. Drugs 2003; 63 (8): 769-802
7. Abbott Laboratories. Kaletra® (lopinavir/ritonavir) capsules [prescribing information; online]. Available from URL: http://www.rxabbott.com/ pdf/kaletrapi.pdf [Accessed 2006 Apr 13]
8. Abbott Laboratories. Kaletra® (lopinavir/ritonavir) tablets (lopinavir/ritonavir) oral solution [prescribing information; online]. Available from URL: http://www.rxabbott.com/pdf/kaletratabpi.pdf [Accessed 2006 Apr 13]