LC-MS/MS assay for quantification of a novel antidiabetic flavone derivative S002-857 in rat plasma, urine and feces: Application in pharmacokinetic studies

Chromatographia

Volumn 73, Issue 9-10, 2011, Pages 905-912

  Gautam, Nagsen ^a   Kushwaha, Hari Narayan ^a   Kumar, Hemant ^a   Pratap, Ram ^a   Singh, Shio Kumar ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Antidiabetic; Excretion; LC MS MS; Pharmacokinetics; S002 857

Indexed keywords

ACETONITRILE; AMMONIUM ACETATE; CENTCHROMAN; FLAVONE DERIVATIVE; S002 857; S002-857; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG FECES LEVEL; DRUG URINE LEVEL; ENVIRONMENTAL TEMPERATURE; FECES; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NONHUMAN; PLASMA; PRIORITY JOURNAL; RAT; URINALYSIS; URINE;

EID: 79958245100     PISSN: 00095893     EISSN: 16121112     Source Type: Journal    
DOI: 10.1007/s10337-011-1978-6     Document Type: Article

References (18)

1. Zhang SQ, Zhong XY, Chen GH, Lu WL, Zhang Q (2008) J Pharm Pharmacol 60:99-105
2. Siddharth NS (2001) J Diabetology 3:11
3. Larmer J (1985) Insulin and oral hypoglycemic drugs, glucogan. In: Gilman AG, Goodman LS, Rall TW, Murad F, (eds). The pharmacological basis of therapeutics, 7th edn. Macmillan, New York
4. Cook NC, Samman S (1996) J Nutr Biochem 7:66-76
5. Belinky PA, Aviram M, Mahmood S, Vaya J (1998) Free Radic Biol Med 24:1419-1429
6. Sharma B, Viswanath G, Salunke R, Roy P (2008) Food Chem 110(3): 697-705
7. Manach C, Donovan JL (2004) Free Radic Res 38:771-785
8. Shah VP, Midha KK, Dighe S, McGilveray IJ, Skelly JP, Yacobi A, Layloff T, Viswanathan CT, Cook CE, McDowall RD, Pittman KA, Spector S (1991) Eur J Drug Metab Pharmacokin 16:249-255
9. Jan WC, Lin LC, Don MJ, Chen CF, Tsai TH (2006) Biomed Chromatogr 20:1163-1171
10. Gautam N, Singh RP, Pratap R, Singh SK (2010) Biomed Chromatogr 24:692-698
11. Oswald S, Scheuch E, Cascorbi I, Siegmund W (2006) J Chromatogr B 830:143-150
12. Kostiainen R, Kotiaho T, Kuuranne T, Auriolo S (2003) J Mass Spectrom 38:357-372
13. Singh RP, Sabarinath S, Gautam N, Gupta RC, Singh SK (2009) J Chromatogr B 877:2074-2080
14. Suryawanshi S, Mehrotra N, Asthana RK, Gupta RC (2006) Rapid Commun Mass Spectrom 20:3761-3768
15. Xu W, Zhang Y, Yang M, Shen Z, Zhang X, Li H (2007) J Pharm Biomed Anal 45:667-672
16. Bi X, Meng Z, Dou G (2007) J Chromatogr B 850:199-205
17. Gautam N, Kushwaha HN, Pratap R, Singh SK (2010) J Pharm Pharmacol 62:604-609
18. Manach C, Donovan JL (2004) Free Radic Res 38:771-785