Liquid chromatographic-tandem mass spectrometry assay for quantitation of a novel antidiabetic S002-853 in rat plasma and its application to pharmacokinetic study

Biomedical Chromatography

Volumn 24, Issue 7, 2010, Pages 692-698

  Gautam, N ^a   Singh, R P ^a   Pratap, R ^a   Singh, S K ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Antidiabetic; Flavonoid; Pharmacokinetics; Rat plasma; Validation

Indexed keywords

BODY FLUIDS; ELECTROSPRAY IONIZATION; HIGH PRESSURE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; POSITIVE IONS; RATS;

ANTIDIABETIC; FLAVONOID; INTERNAL STANDARDS; ITS APPLICATIONS; LC-MS-MS; PHARMACOKINETIC STUDIES; RAT PLASMA; TANDEM MASS SPECTROMETRY; TANDEM-MASS SPECTROMETRY; VALIDATION;

PHARMACOKINETICS;

AMMONIUM ACETATE; ANTIDIABETIC AGENT; CENTCHROMAN; ETHER; FLAVANOID; METHANOL; SOO2 853; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG ABSORPTION; DRUG STABILITY; DRUG STRUCTURE; ENVIRONMENTAL TEMPERATURE; FREEZE THAWING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MALE; NONHUMAN; PH MEASUREMENT; RAT; TANDEM MASS SPECTROMETRY;

RATTUS;

EID: 77953488381     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1348     Document Type: Article

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