In-situ absorption, protein binding and pharmacokinetic studies of S002-853, a novel antidiabetic and antidyslipidaemic flavone derivative in rats

Journal of Pharmacy and Pharmacology

Volumn 62, Issue 5, 2010, Pages 604-609

  Gautam, Nagsen ^a   Kushwaha, Hari Narayan ^a   Pratap, Ram ^a   Singh, Shio Kumar ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

In situ absorption; Pharmacokinetics; Protein binding; Rat plasma; S002 853

Indexed keywords

ANTIDIABETIC AGENT; ANTILIPEMIC AGENT; FLAVONE DERIVATIVE; S 002 853; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG HALF LIFE; DRUG STRUCTURE; GASTROINTESTINAL ABSORPTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; PLASMA PROTEIN BINDING; RAT; SINGLE DRUG DOSE; TANDEM MASS SPECTROMETRY; ULTRAVIOLET SPECTROSCOPY;

EID: 84940542297     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.62.05.0007     Document Type: Article

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