Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice

Journal of Clinical Investigation

Volumn 118, Issue 11, 2008, Pages 3725-3737

  Fu, Jianxin ^a   Gerhardt, Holger ^b   McDaniel, J Michael ^a   Xia, Baoyun ^c   Liu, Xiaowei ^a   Ivanciu, Lacramioara ^a   Ny, Annelii ^d   Hermans, Karlien ^d   Silasi Mansat, Robert ^a   McGee, Samuel ^a   Nye, Emma ^b   Ju, Tongzhong ^c   Ramirez, Maria I ^e   Carmeliet, Peter ^d   Cummings, Richard D ^c   Lupu, Florea ^a   Xia, Lijun ^a,f  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF LEUVEN   (Belgium)

^e BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHYLOMICRON; GLYCAN DERIVATIVE; PODOPLANIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C1GALT1 GENE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ENDOTHELIUM CELL; FATTY LIVER; FEMALE; GENE INACTIVATION; HEMATOPOIETIC CELL; INTESTINE LYMPH; LYMPHANGIOGENESIS; MALE; MOUSE; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENE; VASCULAR DISEASE;

ANIMALS; CELLS, CULTURED; ENDOTHELIAL CELLS; FATTY LIVER; GALACTOSYLTRANSFERASES; LYMPHATIC VESSELS; MICE; MICE, TRANSGENIC; MICROVESSELS; TRANSGENES;

EID: 55849149808     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI36077     Document Type: Article

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