메뉴 건너뛰기




Volumn 29, Issue 6, 2011, Pages 396-404

Potential role of P-gp for flavone-induced diminished apoptosis and increased adenoma size in the small intestine of APCmin/+ mice

Author keywords

Adenomatous polyposis coli; Apoptosis; Cleaved caspase; Flavone; Phosphoglycoprotein 170

Indexed keywords

APC PROTEIN; CASPASE 3; FLAVONE; MATRIX EXTRACELLULAR PHOSPHOGLYCOPROTEIN;

EID: 79958232077     PISSN: 07357907     EISSN: 15324192     Source Type: Journal    
DOI: 10.3109/07357907.2011.587071     Document Type: Article
Times cited : (5)

References (36)
  • 1
    • 75349101848 scopus 로고    scopus 로고
    • APC and its modifiers in colon cancer
    • Kwong LN, Dove WF. APC and its modifiers in colon cancer. Adv Exp Med Biol 2009;656:85-106.
    • (2009) Adv Exp Med Biol , vol.656 , pp. 85-106
    • Kwong, L.N.1    Dove, W.F.2
  • 2
    • 75349102009 scopus 로고    scopus 로고
    • The adenomatous polyposis coli tumor suppressor and Wnt signaling in the regulation of apoptosis
    • Benchabane H, Ahmed Y.The adenomatous polyposis coli tumor suppressor and Wnt signaling in the regulation of apoptosis. Adv Exp Med Biol 2009;656:75-84.
    • (2009) Adv Exp Med Biol , vol.656 , pp. 75-84
    • Benchabane, H.1    Ahmed, Y.2
  • 3
    • 69249222794 scopus 로고    scopus 로고
    • Newperspectives on APC control of cell fate and proliferation in colorectal cancer
    • Phelps RA, Broadbent TJ, StafforiniDM, JonesDA. Newperspectives on APC control of cell fate and proliferation in colorectal cancer. Cell Cycle 2009;8:2549-2556.
    • (2009) Cell Cycle , vol.8 , pp. 2549-2556
    • Phelps, R.A.1    Broadbent, T.J.2    Stafforini, D.M.3    Jones, D.A.4
  • 4
    • 41349091246 scopus 로고    scopus 로고
    • Wnt signaling inside the nucleus
    • DOI 10.1111/j.1349-7006.2007.00716.x
    • Shitashige M, Hirohashi S, Yamada T. Wnt signaling inside the nucleus. Cancer Sci 2008;99:631-637. (Pubitemid 351448063)
    • (2008) Cancer Science , vol.99 , Issue.4 , pp. 631-637
    • Shitashige, M.1    Hirohashi, S.2    Yamada, T.3
  • 5
    • 0034282519 scopus 로고    scopus 로고
    • Transactivation of the multidrug resistance 1 gene by T-cell factor 4/beta-catenin complex in early colorectal carcinogenesis
    • Yamada T, Takaoka AS, Naishiro Y, Hayashi R, Maruyama K, Maesawa C, Ochiai A, Hirohashi S. Transactivation of the multidrug resistance 1 gene by T-cell factor 4/beta-catenin complex in early colorectal carcinogenesis. Cancer Res 2000;60:4761-4766.
    • (2000) Cancer Res , vol.60 , pp. 4761-4766
    • Yamada, T.1    Takaoka, A.S.2    Naishiro, Y.3    Hayashi, R.4    Maruyama, K.5    Maesawa, C.6    Ochiai, A.7    Hirohashi, S.8
  • 6
    • 0028803728 scopus 로고
    • Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
    • Tsujii M, DuBois RN. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 1995;83:493-501.
    • (1995) Cell , vol.83 , pp. 493-501
    • Tsujii, M.1    Dubois, R.N.2
  • 7
    • 0032499771 scopus 로고    scopus 로고
    • The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis
    • Smyth MJ, Krasovskis E, Sutton VR, Johnstone RW. The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis. Proc Natl Acad Sci 1998;95:7024-7029.
    • (1998) Proc Natl Acad Sci , vol.95 , pp. 7024-7029
    • Smyth, M.J.1    Krasovskis, E.2    Sutton, V.R.3    Johnstone, R.W.4
  • 8
    • 0029126764 scopus 로고
    • MDR1/P-glycoprotein expression in colorectal cancer
    • Linn SC, Giaccone G. MDR1/P-glycoprotein expression in colorectal cancer. Eur J Cancer 1995;31A:1291-1294.
    • (1995) Eur J Cancer , vol.31 A , pp. 1291-1294
    • Linn, S.C.1    Giaccone, G.2
  • 10
    • 3543058843 scopus 로고    scopus 로고
    • Pleiotropic molecular effects of the pro-apoptotic dietary constituent flavone in human colon cancer cells identified by protein and mRNA expression profiling
    • DOI 10.1002/pmic.200300754
    • Herzog A, Kindermann B, Döring F, Daniel H, Wenzel U. Pleiotropic molecular effects of the pro-apoptotic dietary constituent flavone in human colon cancer cells identified by protein and mRNA expression profiling. Proteomics 2004;4:2455-2464. (Pubitemid 39025346)
    • (2004) Proteomics , vol.4 , Issue.8 , pp. 2455-2464
    • Herzog, A.1    Kindermann, B.2    Doring, F.3    Daniel, H.4    Wenzel, U.5
  • 11
    • 1242274490 scopus 로고    scopus 로고
    • Identification of biomarkers for the initiation of apoptosis in human preneoplastic colonocytes by proteome analysis
    • DOI 10.1002/ijc.11692
    • Herzog A, Kuntz S, Daniel H, Wenzel U. Identification of biomarkers for the initiation of apoptosis in human preneoplastic colonocytes by proteome analysis. Int J Cancer 2004;109:220-229. (Pubitemid 38240924)
    • (2004) International Journal of Cancer , vol.109 , Issue.2 , pp. 220-229
    • Herzog, A.1    Kuntz, S.2    Daniel, H.3    Wenzel, U.4
  • 12
    • 34547771684 scopus 로고    scopus 로고
    • The suppression of aberrant crypt multiplicity in colonic tissue of 1,2-dimethylhydrazine-treated C57BL/6J mice by dietary flavone is associated with an increased expression of Krebs cycle enzymes
    • DOI 10.1093/carcin/bgm040
    • Winkelmann I, Diehl D, Oesterle D, Daniel H, Wenzel U. The suppression of aberrant crypt multiplicity in colonic tissue of 1,2- dimethylhydrazine-treated C57BL/6J mice by dietary flavone is associated with an increased expression of Krebs cycle enzymes. Carcinogenesis 2007;28:1446-1454. (Pubitemid 47241794)
    • (2007) Carcinogenesis , vol.28 , Issue.7 , pp. 1446-1454
    • Diehl, D.1    Oesterle, D.2    Daniel, H.3    Wenzel, U.4
  • 13
    • 79251524210 scopus 로고    scopus 로고
    • Flavone induces changes in intermediary metabolism that prevent microadenoma formation in colonic tissue of carcinogen-treated mice
    • Winkelmann I,Diehl D, Oesterle D, Daniel D, Wenzel U. Flavone induces changes in intermediary metabolism that prevent microadenoma formation in colonic tissue of carcinogen-treated mice. Mol Nutr Food Res 2010;54:S184-S195.
    • (2010) Mol Nutr Food Res , vol.54
    • Winkelmann Idiehl, D.1    Oesterle, D.2    Daniel, D.3    Wenzel, U.4
  • 14
    • 11144258924 scopus 로고    scopus 로고
    • Activation of mitochondrial lactate uptake by flavone induces apoptosis in human colon cancer cells
    • DOI 10.1002/jcp.20129
    • Wenzel U, Schoberl K, Lohner K, Daniel H. Activation of mitochondrial lactate uptake by flavone-induced apoptosis in human colon cancer cells. J Cell Physiol 2005;202:379-390. (Pubitemid 40041308)
    • (2005) Journal of Cellular Physiology , vol.202 , Issue.2 , pp. 379-390
    • Wenzel, U.1    Schoberl, K.2    Lohner, K.3    Daniel, H.4
  • 15
    • 0023472472 scopus 로고
    • Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa
    • DOI 10.1016/0003-2697(87)90587-2
    • Schagger H, von Jagow G. Tricine-sodium dodecyl sulfatepolyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal Biochem 1987;166:368-379. (Pubitemid 18004907)
    • (1987) Analytical Biochemistry , vol.166 , Issue.2 , pp. 368-379
    • Schagger, H.1    Von Jagow, G.2
  • 16
    • 0033862088 scopus 로고    scopus 로고
    • Specificity of doxorubicin versus rhodamine-123 in assessing P-glycoprotein functionality in the LLC-PK1, LLC-PK1:MDR1 and Caco-2 cell lines
    • DOI 10.1016/S0928-0987(00)00097-X, PII S092809870000097X
    • van der Sandt IC, Blom-Roosemalen MC, de Boer AG, Breimer DD. Specificity of doxorubicin versus rhodamine-123 in assessing P-glycoprotein functionality in the LLC-PK1, LLC-PK1:MDR1 and Caco-2 cell lines. Eur J Pharm Sci 2000;11:207-214. (Pubitemid 30616443)
    • (2000) European Journal of Pharmaceutical Sciences , vol.11 , Issue.3 , pp. 207-214
    • Van Der Sandt, I.C.J.1    Blom-Roosemalen, M.C.M.2    De Boer, A.G.3    Breimer, D.D.4
  • 17
    • 53849141817 scopus 로고    scopus 로고
    • Involvement of P-glycoprotein, multi-drug resistance protein 2 and breast cancer resistance protein in the transport of belotecan and topotecan in Caco-2 and MDCKII cells
    • Li H, Jin HE, Kim W, Han YH, Kim DD, Chung, SJ, Shim, CK. Involvement of P-glycoprotein, multi-drug resistance protein 2 and breast cancer resistance protein in the transport of belotecan and topotecan in Caco-2 and MDCKII cells. Pharm Res 2008;25:2601-2612.
    • (2008) Pharm Res , vol.25 , pp. 2601-2612
    • Li, H.1    Jin, H.E.2    Kim, W.3    Han, Y.H.4    Kim, D.D.5    Chung, S.J.6    Shim, C.K.7
  • 18
    • 0033109776 scopus 로고    scopus 로고
    • Fluorescence spectral properties of the anticancer drug topotecan by steady-state and frequency domain fluorometry with one-photon and multi-photon excitation
    • Gryczynski I, Gryczynski Z, Lakowicz JR, Yang D, Burke TG. Fluorescence spectral properties of the anticancer drug topotecan by steady-state and frequency domain fluorometry with one-photon and multi-photon excitation. Photochem Photobiol 1999;69:421-428. (Pubitemid 129555303)
    • (1999) Photochemistry and Photobiology , vol.69 , Issue.4 , pp. 421-428
    • Gryczynski, I.1    Gryczynski, Z.2    Lakowicz, J.R.3    Yang, D.4    Burke, T.G.5
  • 20
    • 4344577385 scopus 로고    scopus 로고
    • Clinical management of hereditary colorectal cancer syndromes
    • DOI 10.1097/00001574-200401000-00008
    • Half EE, Bresalier RS. Clinical management of hereditary colorectal cancer syndromes. Curr Opin Gastroenterol 2004;20:32-42. (Pubitemid 39117955)
    • (2004) Current Opinion in Gastroenterology , vol.20 , Issue.1 , pp. 32-42
    • Half, E.E.1    Bresalier, R.S.2
  • 21
    • 77951630296 scopus 로고    scopus 로고
    • Primary prevention of colorectal cancer
    • Chan AT, Giovannucci EL. Primary prevention of colorectal cancer. Gastroenterology 2010;138:2029-2043.
    • (2010) Gastroenterology , vol.138 , pp. 2029-2043
    • Chan, A.T.1    Giovannucci, E.L.2
  • 24
    • 72149105299 scopus 로고    scopus 로고
    • Dietary flavonoids suppress azoxymethane-induced colonic preneoplastic lesions in male C57BL/KsJ-db/dbmice
    • Miyamoto S, Yasui Y, Ohigashi H, Tanaka T, Murakami A. Dietary flavonoids suppress azoxymethane-induced colonic preneoplastic lesions in male C57BL/KsJ-db/dbmice. Chem Biol Interact 2010;183:276-283.
    • (2010) Chem Biol Interact , vol.183 , pp. 276-283
    • Miyamoto, S.1    Yasui, Y.2    Ohigashi, H.3    Tanaka, T.4    Murakami, A.5
  • 25
    • 0034660863 scopus 로고    scopus 로고
    • Dietary flavone is a potent apoptosis inducer in human colon carcinoma cells
    • Wenzel U, Kuntz S, Brendel MD, Daniel H. Dietary flavone is a potent apoptosis inducer in human colon carcinoma cells. Cancer Res 2000;60:3823-3831. (Pubitemid 32204574)
    • (2000) Cancer Research , vol.60 , Issue.14 , pp. 3823-3831
    • Wenzel, U.1    Kuntz, S.2    Brendel, M.D.3    Daniel, H.4
  • 26
    • 0345735765 scopus 로고    scopus 로고
    • Nitric Oxide Levels in Human Preneoplastic Colonocytes Determine Their Susceptibility toward Antineoplastic Agents
    • DOI 10.1124/mol.64.6.1494
    • Wenzel U, Kuntz S, Daniel H. NO levels in human preneoplastic colonocytes determine their susceptibility towards anti-neoplastic agents. Mol Pharmacol 2003;64:1494-1502. (Pubitemid 37532238)
    • (2003) Molecular Pharmacology , vol.64 , Issue.6 , pp. 1494-1502
    • Wenzel, U.1    Kuntz, S.2    Daniel, H.3
  • 29
    • 25444448653 scopus 로고    scopus 로고
    • Involvement of adenomatous polyposis coli in colorectal tumorigenesis
    • Jaiswal AS, Balusu R, Narayan S. Involvement of adenomatous polyposis coli in colorectal tumorigenesis. Front Biosci 2005;10:1118-1134.
    • (2005) Front Biosci , vol.10 , pp. 1118-1134
    • Jaiswal, A.S.1    Balusu, R.2    Narayan, S.3
  • 35
    • 23444442691 scopus 로고    scopus 로고
    • Targeting the beta-catenin/APC pathway: A novel mechanism to explain the cyclooxygenase-2-independent anticarcinogenic effects of celecoxib in human colon carcinoma cells
    • DOI 10.1096/fj.04-3274fje
    • Maier TJ, Janssen A, Schmidt R, Geisslinger G, Grösch S. Targeting the beta-catenin/APC pathway: a novel mechanism to explain the cyclooxygenase-2-independent anticarcinogenic effects of celecoxib in human colon carcinoma cells. FASEB J 2005;19:1353-1355. (Pubitemid 41113747)
    • (2005) FASEB Journal , vol.19 , Issue.10 , pp. 1353-1355
    • Maier, T.J.1    Janssen, A.2    Schmidt, R.3    Geisslinger, G.4    Grosch, S.5
  • 36
    • 70349324516 scopus 로고    scopus 로고
    • Mutated K-ras (Asp12) promotes tumourigenesis in Apc (Min) mice more in the large than the small intestines, with synergistic effects between K-ras and Wnt pathways
    • Luo F, Brooks DG, Ye H, Hamoudi R, Poulogiannis G, Patek CE,Winton DJ, Arends MJ. Mutated K-ras (Asp12) promotes tumourigenesis in Apc (Min) mice more in the large than the small intestines, with synergistic effects between K-ras and Wnt pathways. Int J Exp Pathol 2009;90:558-574.
    • (2009) Int J Exp Pathol , vol.90 , pp. 558-574
    • Luo, F.1    Brooks, D.G.2    Ye, H.3    Hamoudi, R.4    Poulogiannis, G.5    Patek, C.E.6    Winton, D.J.7    Arends, M.J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.